scholarly journals Protocol for Chinese Herbal Medicines Decoction Treatment of Angina Pectoris: a Systematic Review With Bayesian Network Meta-analysis

2021 ◽  
Author(s):  
Nan Li ◽  
Wentai Pang ◽  
Fengwen Yang ◽  
Bo Pang ◽  
Xinyao Jin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Angina Pectoris ◽  
Herbal Medicine ◽  
Bayesian Network ◽  
Meta Analysis ◽  
Herbal Medicines ◽  
Cochrane Library ◽  
China National Knowledge Infrastructure ◽  
Chinese Herbal Medicines ◽  
Chinese Herbal

Abstract Background Angina pectoris (AP) is the primary symptom of coronary heart disease. Evidence has shown Chinese herbal medicines can bring benefits to patients suffering from AP. There are many kinds of herbal medicines. However, the difference between them has not been systematically analysed. It is uncertain which one is better. For comparison and ranking, a systematic review and network meta-analysis is needed. Methods We will search for the following 6 electronic databases: China Biological Medicine DataBase(CBM), China National Knowledge Infrastructure(CNKI), WanFang Database, PubMed, Embase and the Cochrane Library, from inception to May 2021. Randomized controlled trials, which aim to assess the efficacy and safety of 5 kinds of Chinese herbal medicine for AP will be included. The outcomes include reduction of AP, improvement of the electrocardiogram and adverse events. The study screening and data extraction will be presented by 2 researchers. The risk of bias will be assessed according to the Cochrane handbook. A Bayesian network meta-analysis will be performed to compare the efficacy of 5 Chinese herbal medicines. Surface under the cumulative rank curve value will be calculated to rank the efficacy of each herbal medicine.DiscussionOur protocol will be expected that the results of this study will provide evidence for Clinical Practice Guideline, clinical decisions, and development of proprietary Chinese medicines.Systematic review registrationPROSPERO registration number: CRD42019146185.

scholarly journals Efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of angina pectoris of coronary heart disease: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Shuang Wang ◽  
◽  
Aidong Liu ◽  
Zhilei Wang ◽  
Yue Zhang
Keyword(s):  
Systematic Review ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Angina Pectoris ◽  
Herbal Medicine ◽  
Chinese Herbal Medicine ◽  
Meta Analysis ◽  
Biomedical Literature ◽  
Efficacy And Safety ◽  
Chinese Herbal

Review question / Objective: This study is the protocol for a systematic review to evaluate the Efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of angina pectoris of coronary heart disease: a systematic review and meta-analysis. we conducted a systematic review and meta-analysis of published randomized clinical trials (RCTs) of such combined therapy in the treatment of angina pectoris of coronary heart disease, It provides a reliable scientific basis for clinicians to use this approach to treat angina pectoris of coronary heart disease. Information sources: We conducted a systematic search for relevant documents in the Chinese and English databases, and the search time is limited to November 23, 2021. The following eight databases are included : PubMed,EMBASE, Web of Science, The Cochrane Library, Chinese Biomedical Literature Database (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang Database.Relevant journals were searched to trace the references included in the study. Other resources will be searched if necessary.

scholarly journals Efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of primary liver cancer: A protocol for systematic review and meta-analysis

2021 ◽  
Author(s):  
Dong Shen ◽  
◽  
Zhuang Xiong ◽  
Yangyang Liu ◽  
Yan Leng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Herbal Medicine ◽  
Liver Cancer ◽  
Chinese Herbal Medicine ◽  
Primary Liver Cancer ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Efficacy And Safety ◽  
Chinese Herbal ◽  
Treatment Information

Review question / Objective: The aim of this systematic review is to valuate the efficacy and safety of acupuncture combined with Chinese herbal medicine in the treatment of primary liver cancer inform clinical practice. To this end, the proposed systematic review will address the following question: Which is the best choice to effective in improving The short-term curative effect is effective, the quality of life is stable, and the survival rate of patients is six months/one year in patients with primary liver cancer, acupuncture combined with Chinese herbal medicine or the best supportive treatment? Information sources: We will search the following databases: PubMed, Web of Science, Embase, AMED, Cochrane Library, CNKI, VIP, CBM, and Wanfang. Additionally, we will manually search all reference lists from relevant systematic reviews to find other eligible studies. We will exclude all conference records, reviews, meta-analyses, newspapers, guides, letters and other documents. When the full text or the required information in the analysis process was missing, the author of the studies was contacted for data.

scholarly journals Efficacy and safety of Chinese herbal medicine combined with Sorafenib in the treatment of primary liver cancer: A protocol for systematic review and meta-analysis

2021 ◽  
Author(s):  
Dong Shen ◽  
◽  
Zhuang Xiong ◽  
Yangyang Liu ◽  
Yan Leng ◽  
...  
Keyword(s):  
Systematic Review ◽  
Herbal Medicine ◽  
Liver Cancer ◽  
Chinese Herbal Medicine ◽  
Primary Liver Cancer ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Publication Date ◽  
Efficacy And Safety ◽  
Chinese Herbal

The aim of this systematic review is to compare Chinese herbal medicine combined with Sorafenib in terms of efficacy and acceptability in the primary liver cancer to better inform clinical practice. To this end, the proposed systematic review will address the following question: Which is the best choice to reduce Efficacy and safety in Patients with primary liver cancer, Chinese herbal medicine combined with Sorafenib or Sorafenib.this systematic review and meta-analysis will evaluate the efficacy and Sorafenib combined with Chinese herbal medicine in the treatment of PLC. Information sources: We will search the following databases from inception up to September 8, 2021: PubMed, Web of Science, Embase, AMED, Cochrane Library, CNKI, VIP, CBM, and Wanfang. There will be no restrictions regarding publication date or language. We will apply a combination of medical keywords and words, including "Sorafenib", "Chinese herbal medicine" and "primary liver cancer". Additionally, we will manually search all reference lists from relevant systematic reviews to find other eligible studies.

scholarly journals The Effect of Chinese Herbal Medicine Gualouxiebaibanxia Decoction for the Treatment of Angina Pectoris: A Systematic Review

2016 ◽  
Vol 2016 ◽  
pp. 1-14 ◽  
Author(s):  
Wei Liu ◽  
Xingjiang Xiong ◽  
Xiaochen Yang ◽  
Fuyong Chu ◽  
Hongxu Liu
Keyword(s):  
Systematic Review ◽  
Angina Pectoris ◽  
Herbal Medicine ◽  
Methodological Quality ◽  
Clinical Evidence ◽  
Meta Analysis ◽  
Beneficial Effects ◽  
Chinese Herbal ◽  
The Poor

We systematically assess the current clinical evidence of Gualouxiebaibanxia (GLXBBX) decoction for the treatment of angina pectoris (AP). We included RCTs testing GLXBBX against conventional drugs and GLXBBX combined with conventional drugs versus conventional drugs. 19 RCTs involving 1730 patients were finally identified, and the methodological quality was evaluated as generally low. The results of the meta-analysis showed that GLXBBX alone had significant effect on improving angina symptoms (RR: 1.24, 95% CI 1.14 to 1.35;P<0.00001), ECG (RR: 1.28[1.13,1.44];P<0.0001), and HDL-C (MD: 0.56[0.54,0.58];P<0.00001) compared with anti-arrhythmic drugs. A significant improvement in angina symptoms (RR: 1.17[1.12,1.22];P<0.00001) and ECG (RR = 1.22; 95% CI =[1.14,1.30];P<0.00001) was observed for GLXBBX plus conventional drugs when compared with conventional drugs. Eight trials reported adverse events without serious adverse effects. GLXBBX appears to have beneficial effects on improvement of ECG and reduction of angina symptoms in participants with AP. However, the evidence remains weak due to the poor methodological quality of the included studies. More rigorous trials are needed to confirm the results.

scholarly journals Effect of somatometric parameters on the prevalence and severity of varicocele: a systematic review and meta-analysis

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Runqing Li ◽  
Junjie Liu ◽  
Yushan Li ◽  
Quanxian Wang
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Cochrane Library ◽  
China National Knowledge Infrastructure ◽  
Random Effects Models ◽  
Knowledge Infrastructure ◽  
Regression Test ◽  
Mean Differences ◽  
Q Statistic ◽  
The Relationship

Abstract Background Published studies have shown contradictory results regarding the relationship between somatometric parameters and varicoceles. We performed a systematic review and meta-analysis to investigate the possible effects of age, height, weight, and body mass index (BMI) on the presence and severity of varicoceles. Methods Databases including EMBASE, MEDLINE, PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), Web of Science, and Google Scholar were systematically searched to identify relevant articles published up to March 2020. Two researchers independently identified eligible articles and extracted data. Cochran’s Q statistic and I2 statistics were used to assess heterogeneity. Meta-analysis was performed using StataSE 12.0 software (StataCorp LP, USA). Random-effects models were used to obtain the weighted mean differences (WMDs) and 95% confidence intervals (CIs). Publication bias was assessed using Begg’s funnel plot and Egger’s regression test. Results The search strategy produced 272 articles, of which 18 articles were eligible according to the inclusion/exclusion criteria. A total of 56,325 patients with varicocele and 1,334,694 patients without varicocele were included in the meta-analysis to evaluate the effect of somatometric parameters on the presence and severity of varicocele. The overall results demonstrated that the presence of varicoceles was significantly associated with height (WMD = 1.41, 95% CI = 1.07 to 1.74, P < 0.001) and inversely correlated with BMI (WMD = − 1.35, 95% CI = -1.67 to − 1.03, P < 0.001) but not with age (WMD = -0.93, 95% CI = -2.19 to 0.33, P = 0.149) or weight (WMD = 0.24, 95% CI = -2.24 to 2.72, P = 0.850). The severity of varicocele was inversely correlated with increased BMI but not with age. Conclusion The presence of varicoceles was significantly associated with height and inversely correlated with BMI.

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