scholarly journals Isolated Progressive Enlargement of Head Mass as the First Symptom: A Rare Case Report of Cranial Metastasis of Hepatocellular Carcinoma and Literature Review

2021 ◽  
Author(s):  
Yuan-yuan Liu ◽  
Zhi-hua Zhou ◽  
Shuai Hu ◽  
Xin Su ◽  
jinxu zhou
Keyword(s):  
Hepatocellular Carcinoma ◽  
Rare Case ◽  
Life Quality ◽  
Surgical Excision ◽  
Parietal Bone ◽  
Primary Hepatocellular Carcinoma ◽  
Intracranial Metastasis ◽  
Skull Metastasis ◽  
Painless Mass ◽  
Progressive Enlargement

Abstract Background: This article presents a rare case of skull metastasis of primary hepatocellular carcinoma that manifests the isolated progressive enlargement of the head mass as the first symptom. Case presentation:A 65-year-old female patient presented an isolated painless mass in the head, which grew rapidly over the last month. Head CT revealed a 6.4 cm×5.6cm osteolytic destruction in the right parietal bone. MRI further revealed that the occupation was significantly enhanced in the T1 reinforced phase. The patient underwent total surgical resection. Postoperative pathology confirmed that the head mass was the skull metastasis from hepatocellular carcinoma (HCC). Conclusion: The case of skull metastasis from primary hepatocellular carcinoma is rare, and HCC patient with intracranial metastasis tends to have a rather poor prognosis. Surgical excision of the metastatic mass and radiotherapy can improve the life quality and prolong the survival time of the patient.

scholarly journals A rare case of cranial metastasis from an initial presentation of hepatocellular carcinoma

2020 ◽  
Vol 8 (8) ◽  
pp. 3088
Author(s):  
Chetan Kalal ◽  
Adinath Wagh ◽  
Atif Patel ◽  
Harshad Joshi ◽  
Ravindra Surude ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Rare Case ◽  
Parietal Bone ◽  
Initial Presentation ◽  
Cross Sectional ◽  
Detailed History ◽  
Cross Sectional Imaging ◽  
History Of ◽  
Sectional Imaging ◽  
Cranial Metastasis

Cranial metastases from hepatocellular carcinoma (HCC) has been seldom reported. Reported herein is the case of a painless parietal bone mass as an initial presentation of HCC in a 63-year-old female patient who was subsequently diagnosed to have HCV related cirrhosis. The biopsy from cranial lesion was confirmatory of HCC on immunohistochemistry. The patient had no known history of chronic liver disease. The presented diagnosis was made through detailed history, laboratory parameters and cross sectional imaging.

scholarly journals S2778 Rare Case of Skull Metastasis From Recurrent Hepatocellular Carcinoma

2021 ◽  
Vol 116 (1) ◽  
pp. S1158-S1159
Author(s):  
Soumya Shekhar ◽  
Sudha Kodali ◽  
David Victor ◽  
Akshay Shetty
Keyword(s):  
Hepatocellular Carcinoma ◽  
Rare Case ◽  
Skull Metastasis ◽  
Recurrent Hepatocellular Carcinoma

scholarly journals Solitary Skull Metastasis as Initial Manifestation of Hepatocellular Carcinoma – A Case Report

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Ellyda MN ◽  
Mohd Shafie A
Keyword(s):  
Hepatocellular Carcinoma ◽  
Clinical Manifestations ◽  
Metastatic Lesion ◽  
Primary Hepatocellular Carcinoma ◽  
Primary Malignancy ◽  
Initial Manifestation ◽  
Skull Metastasis ◽  
Skull Tumors ◽  
Prostate Cancers ◽  
Cranial Metastasis

Metastatic spread of tumors to the skull is quite unusual and often represents diagnostic and therapeutic issues. Skull involvement can be observed in various neoplasms of epithelial origin and are most often due to lung, breast, thyroid, kidney and prostate cancers. However, skull metastases from hepatocellular carcinoma (HCC) have been rarely reported. The prognosis for patients with hepatocellular carcinoma is so poor that treatment of such distant metastatic lesion cannot be achieved before death occurs due to the primary malignancy. Therefore, the clinical manifestations of cranial metastasis prior to that of primary hepatocellular carcinoma have rarely been reported. This case illustrates a rare case of skull metastasis as an initial manifestation of hepatocellular carcinoma. Although a solitary skull metastasis prior to the diagnosis of HCC demonstrates rare metastatic behavior for HCC, especially in Asia, skull metastases from HCC should be included in the differential diagnosis of skull tumors, even if the patient is asymptomatic of liver cirrhosis.

scholarly journals Hepatocellular Carcinoma Masquerading as a Large Renal Mass with Hepatic Invasion

2010 ◽  
Vol 10 ◽  
pp. 301-307 ◽  
Author(s):  
Joseph R. N. Zabell ◽  
Kenneth G. Nepple ◽  
Neal W. Wilkinson ◽  
Laila Dahmoush ◽  
Richard D. Williams
Keyword(s):  
Hepatocellular Carcinoma ◽  
Unusual Case ◽  
Surgical Excision ◽  
Primary Hepatocellular Carcinoma ◽  
Rare Occurrence ◽  
Tumor Spread ◽  
Radiographic Findings ◽  
Direct Extension ◽  
Primary Origin ◽  
Hepatic Invasion

Large masses are evaluated with imaging to assess primary origin and tumor spread. We present the unusual case of a 53-year-old male with a 17-cm right upper quadrant mass suspected to be renal or adrenal in origin based on radiographic findings. After surgical excision, the mass was subsequently discovered to be primary hepatocellular carcinoma with direct extension to the kidney and adrenal gland. A diagnosis of chronic hepatitis B was made postoperatively. Primary hepatocellular carcinoma with direct renal extension is an exceedingly rare occurrence based on our experience and review of the published literature.

scholarly journals Rare case of hepatocellular carcinoma metastasising to the pituitary and cavernous sinus causing panhypopituitarism and bilateral ophthalmoplegia

2020 ◽  
Vol 13 (10) ◽  
pp. e236377
Author(s):  
Jayachidambaram Ambalavanan ◽  
Monica Peravali ◽  
David J Perry
Keyword(s):  
Hepatocellular Carcinoma ◽  
Cavernous Sinus ◽  
Rare Case ◽  
Primary Hepatocellular Carcinoma ◽  
Review Of The Literature ◽  
Unique Case ◽  
Pituitary Metastases

Pituitary metastases, especially from a primary hepatocellular carcinoma (HCC), are rare. Review of the literature revealed only few cases reporting pituitary metastases complicated by panhypopituitarism from HCC. Calvarial metastases from HCC are even more rare. Here, we present a unique case of primary HCC with metastases to both the calvarium and the pituitary causing panhypopituitarism and bilateral ophthalmoplegia, respectively. To our knowledge, this is the first reported case of two unique and rare complications from metastatic HCC.

scholarly journals Schwannoma of the cervical vagus nerve: a rare case report

2017 ◽  
Vol 4 (1) ◽  
pp. 263 ◽  
Author(s):  
Chandra Mohan Setty L. N.
Keyword(s):  
Peripheral Nerves ◽  
Rare Case ◽  
Relevant Literature ◽  
Surgical Excision ◽  
Neck Masses ◽  
Complete Surgical Excision ◽  
Complete Surgical Resection ◽  
Rare Case Report ◽  
Painless Mass ◽  
Nerve Of Origin

<p class="abstract"><span lang="EN-IN">Schwannomas, also called as neurilemomas, are well-encapsulated, slowly growing tumors that arise from schwann cells of peripheral nerves. Clinically, schwannomas present as asymptomatic, slowly enlarging lateral neck masses and so they tend to present late. The nerve of origin is not often made until the time of surgery. Preoperative diagnosis is aided by imaging studies such as magnetic resonance imaging and computed tomography. The treatment of choice of schwannomas of the neck typically involves complete surgical resection. Rapidly growing tumors with evidence of invasion, or complete loss of nerve function should trigger complete surgical excision of the tumor. Here, we report a rare case of cervical vagal schwannoma in a 45 year old female who got admitted with the complaint of a firm, painless mass on the left side of the neck. The management of the case is discussed along with the relevant literature.</span></p>

Giant pedunculated liver mass: primary hepatocellular carcinoma masquerading as hepatic haemangioma

2021 ◽  
Vol 14 (9) ◽  
pp. e242625
Author(s):  
Olivia Cohen ◽  
Muhammad Aleem ◽  
Steven Wolberink ◽  
Miklos Attila Perenyei
Keyword(s):  
Risk Factors ◽  
Hepatocellular Carcinoma ◽  
Case Reports ◽  
Surgical Excision ◽  
Sporadic Case ◽  
Primary Hepatocellular Carcinoma ◽  
Free Fluid ◽  
Liver Mass ◽  
History Of ◽  
Hepatic Haemangioma

A woman in her mid-60s was referred to surgeons with a 2-week history of worsening right-sided abdominal pain. CT demonstrated a large encapsulated, pedunculated hepatic lesion with active intracapsular bleeding and free fluid but nil further lesions. Findings suggested giant hepatic haemangioma; surgical excision took place the following day. Histopathology however confirmed malignancy. Pedunculated hepatocellular carcinoma (HCC) is rare but characteristically large and encapsulated. Sporadic case reports indicate that diagnosis is typically challenging and delayed with liver metastases at presentation. This case describes a patient with no clear risk factors for HCC found to have a well-defined, encapsulated and pedunculated mass but no detected metastasis or other lesions on initial CT. In this instance, subsequent MRI did identify further lesions in the liver. Such cases are limited in the literature: much remains to be learnt regarding presentation, differential diagnoses, investigation and management.

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