scholarly journals Hemostasis Effect of Absorbable Regenerative Oxidized Cellulose Materials in Colorectal Cancer Surgery

2021 ◽  
Author(s):  
Jingmao Lao ◽  
Wei Deng
Keyword(s):  
Colorectal Cancer ◽  
Cancer Surgery ◽  
Control Group ◽  
Oxidized Cellulose ◽  
Observation Group ◽  
Colorectal Cancer Surgery ◽  
Drainage Volume ◽  
Hemostatic Effect ◽  
Cellulose Material

Abstract Absorbable oxidized cellulose hemostatic materials are widely used in hemostasis of veins, capillaries or smaller arteries because of their wide sources, low cost, and high biocompatibility. However, in view of the different application sites, the hemostatic effect of absorbable oxidized cellulose in different surgeries may be different, and its hemostatic effect in patients with colorectal cancer still needs more research to confirm. Therefore, this article explores the in vitro degradation of the absorbable regenerated oxidized cellulose material and its hemostatic effect in colorectal cancer surgery. Explore the in vitro degradation products that can absorb oxidized cellulose. The 44 patients undergoing colon cancer surgery were selected and randomly divided into control group (22 cases, absorbable oxidized cellulose material to stop bleeding) and observation group (22 cases, ordinary Sterile gauze to stop bleeding). The intraoperative blood loss, 3 days postoperative drainage volume, total drainage volume, and operation time of the two groups were recorded. The recovery of intestinal function after operation in the two groups was observed. The in vitro complete degradation time of the absorbable oxidized cellulose material is about 12 days. The degradation products are glucose and cellobiose, which are safe and harmless to the human body. The intraoperative blood loss, drainage volume, total drainage volume, and operation time of the observation group were significantly lower than those of the control group (P <0.05), and the postoperative intestinal function recovery of the observation group was better than that of the control group (P <0.05). In addition, there was no significant difference in the incidence of adverse reactions between the observation group and the control group (P > 0.05). Absorbable oxidized cellulose material has a good hemostatic effect in colorectal cancer surgery, and does not increase the risk of adverse reactions in patients after surgery. It is worthy of popularization and application.

Evaluation of the efficacy of peritoneal lavage with distilled water in colorectal cancer surgery: in vitro and in vivo study

2014 ◽  
Vol 50 (3) ◽  
pp. 287-297 ◽  
Author(s):  
Kenichi Takemoto ◽  
Atsushi Shiozaki ◽  
Daisuke Ichikawa ◽  
Shuhei Komatsu ◽  
Hirotaka Konishi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Peritoneal Lavage ◽  
Cancer Surgery ◽  
In Vivo Study ◽  
Distilled Water ◽  
Colorectal Cancer Surgery

scholarly journals Preliminary Results of an Exercise Program After Laparoscopic Resective Colorectal Cancer Surgery in Non-Metastatic Adenocarcinoma: A Pilot Study of a Randomized Control Trial

Medicina ◽  
2020 ◽  
Vol 56 (2) ◽  
pp. 78
Author(s):  
Gabriele Mascherini ◽  
Maria Novella Ringressi ◽  
Jorge Castizo-Olier ◽  
Georgian Badicu ◽  
Alfredo Irurtia ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Fat Mass ◽  
Elective Surgery ◽  
Cell Mass ◽  
Exercise Program ◽  
Cancer Surgery ◽  
Lower Limbs ◽  
Control Group ◽  
Colorectal Cancer Surgery ◽  
Preliminary Results

Background and objectives: Performing physical exercise after a colorectal cancer diagnosis is associated with lower mortality related to the tumor itself. In order to improve physical recovery after elective surgery, there are no specific exercise protocols after discharge from the hospital. The purpose of this study is to show the preliminary results of an exercise program after colorectal cancer surgery. Materials and Methods: Six patients with non-metastatic colorectal adenocarcinoma addressed to respective laparoscopic were randomly assigned to a mixed supervised/home-based exercise program for six months and compared to a control group without exercise. To assess the effectiveness of the program, functional and body composition parameters were evaluated. Results: Three months after surgery, the exercise group increased flexibility (p <0.01, ES = 0.33), strength of lower limbs (p <0.01, ES = 0.42) and aerobic capacity (p <0.01, ES = 0.28). After surgery, the six patients experienced a significant reduction in body mass index (BMI) and free fat mass. More specifically, fat mass reached the lowest values, with a concomitant increase in cell mass after six months (p <0.01, ES = 0.33). This did not occur in the control group. Conclusions: Colorectal cancer treatment induces a reduction in physical function, particularly during the first six months after treatment. A mixed exercise approach appears promising in countering this process after colorectal cancer surgery.

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