scholarly journals Randomized Control Trial of Short Infusion of Low Dose Ketamine Vs Intravenous Morphine as Adjunct Analgesia for Acute Long Bone Fracture Pain in Emergency Department

2021 ◽  
Author(s):  
Elisa Audrey Eddie ◽  
Ahmad Zulkarnian Ahmad Zahedi ◽  
SABARIAH FAIZAH JAMALUDDIN
Keyword(s):  
Bone Fracture ◽  
Low Dose ◽  
Rating Scale ◽  
Long Bone ◽  
Numerical Pain Rating Scale ◽  
Short Infusion ◽  
Long Bone Fracture ◽  
Intravenous Morphine ◽  
The Mean ◽  
Pain Rating Scale

Abstract BackgroundKetamine is known as an alternative for pain control, but reports of emergency reactions limits its widespread use. We assessed the efficacy of short infusion of low dose ketamine (LDK) compared with intravenous morphine (MOR) as adjunct analgesia for acute long bone fracture pain.MethodsPatients aged 18-60 years old, with acute long bone fracture and with numerical pain rating scale (NPRS) of 6 or more after 3mg intravenous morphine were eligible for enrolment. Subjects were consented and randomized to either short infusion LDK (0.3mg/kg) over 15 minutes or intravenous morphine (MOR) (0.1mg/kg) over 5 minutes. Evaluations of NPRS score and vital signs occurred at 15, 30, 60, 90 and 120 minutes. The primary outcome from this study was the mean reduction of numerical pain rating scale (NPRS) score from baseline and the mean time to achieve ³ 3 score reductions in NPRS. The secondary outcomes were the incidence of adverse events and mean consumption of rescue analgesia.ResultsFifty-eight subjects were enrolled (MOR 27, LDK 31). Demographic variables and baseline NPRS scores MOR (8.33) vs LDK (8.84) were similar. The mean reduction of NPRS were significantly different between LDK (Mean= 3.1, SD=2.03) and MOR (Mean =1.8, SD 1.59), p= 0.009 at 30 minutes. Incidence of dizziness was reported higher in Ketamine group 19.4% (p=0.026).ConclusionWhen used as an adjunct, short infusion low-dose ketamine at 0.3mg/kg over 15minutes provides greater analgesic effect in comparison to intravenous morphine alone for acute long bone fracture pain but has higher incidence of dizziness.Trial RegistrationNational Medical Research Register: https://www.nmrr.gov.my/ Registered 24 November 2017 ID:NMRR-17-3184-38970

scholarly journals Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice

2021 ◽  
Vol 28 ◽  
pp. 39-46
Author(s):  
Ina Lackner ◽  
Birte Weber ◽  
Melanie Haffner-Luntzer ◽  
Simona Hristova ◽  
Florian Gebhard ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Bone Fracture ◽  
Long Bone ◽  
Cardiac Inflammation ◽  
Long Bone Fracture

Long Bone Fracture

1998 ◽  
pp. 353-356
Author(s):  
Michael J. Hejna
Keyword(s):  
Bone Fracture ◽  
Long Bone ◽  
Long Bone Fracture

Comparison of Intramedullary Nailing and Plate Fixation for the Treatment of Nonunion of the Long Bone Fracture on Lower Extermities.

2000 ◽  
Vol 13 (2) ◽  
pp. 327
Author(s):  
Jong Seok Park ◽  
Jae Hoon Lee ◽  
Hee Kwon ◽  
Jae Eung Yoo ◽  
Joon Min Song ◽  
...  
Keyword(s):  
Intramedullary Nailing ◽  
Bone Fracture ◽  
Plate Fixation ◽  
Long Bone ◽  
Long Bone Fracture

scholarly journals Effectiveness of Strengthening and Aerobic Exercises among Geriatrics with Arthritis

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 593-598
Author(s):  
Tamilselvi S ◽  
Anshu Gloria Ekka ◽  
Arul Jothi L
Keyword(s):  
Aerobic Exercise ◽  
Rating Scale ◽  
Nursing Intervention ◽  
Control Group ◽  
Research Approach ◽  
Intensity Level ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale ◽  
Experimental Group

Joint inflammation might be a term regularly acclimated mean any confusion that influences joints. Manifestations for the most part, incorporate joint torment and firmness. Different manifestations may incorporate redness, warmth, growing, the diminished scope of movement of the influenced joints. The aim of the study is to determine the effectiveness of strengthening and aerobic exercise among geriatrics with arthritis. A quantitative research approach with a quasi-experimental research design was used for the present study. A total of 60 arthritis clients who fall in the inclusion criteria were selected by purposive sampling technique, among which 30 samples were in the experimental group and 30 in the control group. The data were collected for both the groups, followed by the pre-test was conducted on the 1st day, the intensity level of pain was assessed by the numerical pain rating scale followed by the exercises which are effective in arthritis are a range of motion exercise, strengthening exercises (hand towel knee exercises, knee flexion, long arc quads), aerobic exercise (brisk walking) was initiated only in the experimental group. The post-test was conducted on 7th day and the level of pain was assessed by a numerical pain rating scale in both the groups. The results revealed that there was a significant reduction in the level of pain at p<0.0001 after the intervention among the experimental group. Thus, the study proves that strengthening and aerobic exercises can be used as an effective nursing intervention for reducing the arthritis pain among the geriatrics and it is easily applicable exercises, and also considered as a less cost-effective. These exercises can be practiced at home without any stress or harm and it has less side effect as compared to that of pharmacological interventions. 

scholarly journals Effectiveness of Progressive Resisted Exercise along with Conventional Exercise and Conventional Exercise Program alone in Subjects with Text Neck Syndrome

2021 ◽  
pp. 536-542
Author(s):  
Divya Jain ◽  
Swapna Jawade ◽  
Neha Chitale
Keyword(s):  
Neck Pain ◽  
Pain Intensity ◽  
Conventional Therapy ◽  
Rating Scale ◽  
Neck Disability Index ◽  
Exercise Program ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Neck Disability ◽  
Pain Rating Scale

Background: "Text neck" is a term coined to describe the posture created by leaning forward for lengthy periods of time, such as when reading and texting on a cellphone which has been linked to stress injuries. Neck pain, upper back discomfort, shoulder pain, frequent headaches, and greater curvature of the spine are all dangerous indications of text neck. According to a survey, 35% of smartphone users suffer from text neck syndrome. People between the ages of 15 and 18 are more likely to have neck pain. This protocol has been created that describes the design of comparative study to evaluate effectiveness of progressive resisted exercise along with conventional exercise and conventional exercise program alone in text neck syndrome. Methods: The participants (n=80) will be recruited in the study suffering from text neck syndrome and meeting the inclusion criteria. Two groups will be formed such that patients in group A will be treated with conventional therapy and group B will be treated with progressive resisted exercise (PRE) along with conventional therapy. The protocol will cover 4 weeks of treatment. In the rehabilitation period, we will evaluate the pain intensity, strength of neck muscles and functional activity. Our outcome measures will be- Numerical pain rating scale (NPRS) and Neck disability index (NDI). Discussion: Efficacy of the intervention will be evaluated by analyzing the pain intensity by using Numerical pain rating scale (NPRS) and level of functional disability by using Neck disability index (NDI). The result of the study will significantly provide affirmation on either using combination therapy of PRE with conventional exercise or conventional exercise alone.

scholarly journals Effectiveness of Cryotherapy on Pain Reduction During Arteriovenous Fistula Puncture Among Patients Undergoing Hemodialysis

2020 ◽  
Vol 11 (3) ◽  
pp. 4314-4317
Author(s):  
Thamu Priyadharshini N T
Keyword(s):  
Rating Scale ◽  
Life Support ◽  
Pain Reduction ◽  
Control Group ◽  
Pain Rating ◽  
Av Fistula ◽  
Numerical Pain Rating Scale ◽  
Significant Difference ◽  
Pain Rating Scale ◽  
Experimental Group

Dialysis is performed as critical life support when the patient is suffering acute and chronic kidney failure. The study focus on to determine effectiveness of on pain reduction during AV fistula puncture among patients undergoing . The population comprised of patients in . Experimental Research design was utilized for this study. The investigators assess the pain on AV fistula puncture among the patients with the assistance of numerical pain rating scale, Sixty samples (30 experimental group and 30 control group)were selected by probability simple random (Numerical table method)sampling technique, the data was gathered through the Numerical Pain Rating scale and demographic variables. The pain on AV fistula puncture of the experimental group and control group were calculated by paired’ test for experimental group (‘t’ = 18) and in control group, (‘t’ =1.5). This proves that there is a significant difference in test and post test levels of pain on AV fistula puncture in the experimental group at 0.05 levels. It indicated that the given was effective. The implication of the findings indicated that given was effective for pain reduction during AV fistula puncture among patients. : , pain on AV fistula puncture, patients. implication of the findings indicated that given was effective for pain reduction during AV fistula puncture among patients.

scholarly journals Initial experience of complete laparoscopic radical nephroureterectomy combined with transvesical laparoscopic excision of distal ureter in patients with upper urinary tract cancer

2020 ◽  
Author(s):  
Makito Miyake ◽  
Nobutaka Nishimura ◽  
Katsuya Aoki ◽  
Chihiro Ohmori ◽  
Takuto Shimizu ◽  
...  
Keyword(s):  
Rating Scale ◽  
Upper Urinary Tract ◽  
Initial Experience ◽  
Radical Nephroureterectomy ◽  
Specimen Extraction ◽  
Distal Ureter ◽  
Laparoscopic Excision ◽  
Numeric Pain Rating Scale ◽  
The Mean ◽  
Pain Rating Scale

Abstract Background: Selecting the treatment procedure for cancer patients is a challenging task. We report our initial experience of complete laparoscopic radical nephroureterectomy (RNU) for patients with upper urinary tract urothelial cancer (UTUC).Methods: A total of four patients with UTUC underwent complete laparoscopic RNU combined with transvesical laparoscopic excision of the distal ureter using three 5-mm ports. Transvaginal specimen extraction was applied in female patients to reduce incisional pain and improve cosmesis. Peri-operative complications were evaluated using the Clavien–Dindo classification system. Postoperative pain was evaluated during hospitalization using a numeric pain rating scale (scales of 1 to 10). Patients who underwent retroperitoneal laparoscopic surgery combined with open excision of the distal ureter during the same period were included as a control group (conventional RNU, consisting of laparoscopic nephrectomy with open bladder cuff excision) for pain scale evaluation.Results: The novel surgery was successfully completed for all four patients (two males and two females). The mean pneumoperitoneum time for retroperitoneoscopic nephroureterectomy and specimen extraction was 174 min, while the mean pneumovesicum time for the ureteral orifice excision was 88 min. One male patient had bladder leakage at the suture site of the bladder wall, which lasted for two weeks. No patient experienced recurrent disease during the follow-up period (median, 10 months). Mild to moderate pain lasted for 5 or 6 days after RNU. A couple of days after surgery, the numeric pain rating scale of complete laparoscopic RNU and conventional RNU group reached its peak level at 3.0 ± 1.8 and 5.3 ± 2.8, respectively. There was no statistical difference in the degree of postoperative pain (P=0.31).Conclusions: We described our initial experience and outcome of complete laparoscopic RNU for UTUC. Further experience and research are required to determine whether this advanced laparoscopic technique yields better outcomes and has true clinical value.

scholarly journals EFEKTIVITAS DAN EFEK SAMPING PENGGUNAAN GABAPENTIN PADA PASIEN NEUROPATI DIABETIK DI RSUP DR. WAHIDIN SUDIROHUSODO MAKASSAR

2018 ◽  
Vol 22 (2) ◽  
pp. 44-47
Author(s):  
Zhulhajsyirah Zhulhajsyirah ◽  
Elly Wahyudin ◽  
Jumriani Tammas
Keyword(s):  
Rating Scale ◽  
P Value ◽  
Pain Rating ◽  
Numerical Pain Rating Scale ◽  
Pain Rating Scale

Penelitian ini bertujuan untuk mengetahui dan menganalisis efektivitas  penggunaan gabapentin  terhadap penurunan derajat nyeri pada  pasien neuropati diabetik di  RSUP Wahidin Sudirohusodo Makassar  yang diukur dengan menggunakan instrumen  Numerical Pain Rating Scale (NPRS) efek samping  penggunaan  gabapentin   pada  pasien neuropati diabetik di  RSUP DR. Wahidin Sudirohusodo Makassar. Penelitian ini dilaksanakan di Poliklinik Saraf dan Poliklinik Endokrin Instalasi Rawat Jalan RSUP DR. Wahidin Sudirohusodo Makassar pada bulan april-juni 2018. Jenis penelitian ini adalah penelitian observasional non eksperimental dengan  desain penelitian  cros sectional. Metode yang digunakan dalam penelitian ini adalah dengan melakukan wawancara dan pengukuran skala nyeri pada pasien neuropati diabetik. Data dianalisis dengan menggunakan analisis statistik uji Wicoxon Signed Ranks Test. Hasil penelitian menunjukkan bahwa efek terapi gabapentin sebelum dan sesudah   pemberian pada 21 pasien neuropati diabetik menunjukkan adanya penurunan skala nyeri  dengan penurunan rata-rata sebesar 2,14 dengan nilai  p-value<0,05 yang berarti  berbeda secara signifikan dalam menurunkan nyeri neuropati. Sedangkan Efek Samping yang terjadi setelah pemberian gabapentin yaitu, mengantuk dan pusing 14%, mengantuk 29%, pusing 5% dan tidak mengalami efek samping 52%.

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