Reference values of respiratory impedance with impulse oscillometry in healthy Chinese adults

2020 ◽  
Author(s):  
Xiaolin Liang ◽  
Yi Gao ◽  
Weijie Guan ◽  
Jing Du ◽  
Li Chen ◽  
...  
Keyword(s):  
Final Analysis ◽  
Specific Reference ◽  
Respiratory Impedance ◽  
Impulse Oscillometry ◽  
Chinese Adults ◽  
European Respiratory Society ◽  
Clinical Trial Registration ◽  
Normal Ranges ◽  
Normal Individuals ◽  
Reference Equations

Abstract Background: Impulse oscillometry (IOS) is a non-invasive pulmonary function test for measuring respiratory impedance. Available reference equations of IOS indices for adults are limited. The aim of this study was to develop reference equations of IOS indices for Chinese adults.Methods: In a multicentral, cross-sessional study of impulse oscillometry in Chinese adults, IOS data from healthy subjects were collected from 19 general hospitals across China was between 2016 and 2018. IOS measurements were conducted in accordance with recommendations of the European Respiratory Society. Multiple linear regression was performed to develop sex-specific reference equations of IOS indices.Results: IOS measurements were performed in 1318 subjects, of which 567 subjects were defined as healthy normal individuals with acceptable IOS data and were included in the final analysis. Reference equations and limits of normal (LLN/ULN) of IOS indices were developed separately for males and females. Height but not age was shown to be the most influential contributor to IOS indices. The reference equations currently used in lung function laboratories predicted higher R5 and X5. Normal ranges of R5 and X5 recommended by the equipment manufacturer were clearly different from the ULN/LLN derived from the reference equations.Conclusions: Reference equations of IOS indices for Chinese adults from a wide region were provided in this study. It is necessary to update new IOS reference equations and adopt ULN/LLN as normal ranges of IOS indices.Clinical Trial Registration: This study was registered at www.clinicaltrials.gov as part of a larger study NCT03467880.

scholarly journals Reference values of respiratory impedance with impulse oscillometry in healthy Chinese adults

2021 ◽  
Vol 13 (6) ◽  
pp. 3680-3691
Author(s):  
Xiao-Lin Liang ◽  
Yi Gao ◽  
Wei-Jie Guan ◽  
Jing Du ◽  
Li Chen ◽  
...  
Keyword(s):  
Reference Values ◽  
Respiratory Impedance ◽  
Impulse Oscillometry ◽  
Chinese Adults ◽  
Healthy Chinese

Abstract 1601: Comprehensive Evaluation of the Left Ventricular Systolic and Diastolic Synchronicity in 160 “Completely” Healthy Normal Volunteers Using Tissue Doppler Echocardiography

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Hyung-Kwan Kim ◽  
Keun-Ho Park ◽  
Suna-A Chang ◽  
Jin-Shik Park ◽  
Hyun-Jae Kang ◽  
...  
Keyword(s):  
Age Groups ◽  
Mitral Annulus ◽  
Tissue Doppler ◽  
Left Ventricular ◽  
Doppler Imaging ◽  
Cardiac Resynchronization ◽  
Specific Reference ◽  
Reference Ranges ◽  
Normal Ranges ◽  
Mitral Annulus Velocity

Background Growing use of the left ventricular(LV) systolic(LVSIsys) and diastolic synchronicity indexes(LVSIdia) in selecting potential responders to cardiac resynchronization therapy(CRT) has created a need for normative reference values. This study was performed to determine reference ranges for tissue Doppler imaging-derived LVSIsys and LVSIdia, and to assess their relationships to age and conventional parameters reflecting LV systolic and diastolic functions. Methods and Results We recruited 160 completely healthy volunteers (45±13yrs, 104 men) free of any systemic or cardiovascular disease. Maximal difference and SD of time to peak systolic and early diastolic velocities for LVSIsys and LVSIdia were measured using 6- and 12-segment models. Table and Figure represent normal ranges. Aging was not found to significantly change LVSIsys, whereas LVSIdia progressively and consistently increased with age. Significant correlations were observed between LVSIdia and parameters representing LV diastolic function, i.e. early mitral inflow velocity and its deceleration time, and early mitral annulus velocity. A physiologic rise in LV mass/Ht 2.7 showed a weak, but significant correlation with LVSIdia( r = 0.15 to 0.22), but not with LVSIsys. On multivariate analysis, age-dependent increase in LVSIdia was confirmed. Conclusions Age-specific reference ranges for LVSIsys and LVSIdia are presented here. LVSIsys remain stable throughout age groups, whereas LVSIdia progressively increases with age. These data given here will be useful for defining abnormal LV synchronous contraction and relaxation, and help better select patients likely to respond favorably to CRT.

scholarly journals Spirometry reference values for Black adults in Brazil

2018 ◽  
Vol 44 (6) ◽  
pp. 449-455 ◽  
Author(s):  
Tarciane Aline Prata ◽  
Eliane Mancuzo ◽  
Carlos Alberto de Castro Pereira ◽  
Silvana Spíndola de Miranda ◽  
Larissa Voss Sadigursky ◽  
...  
Keyword(s):  
Reference Values ◽  
Linear Equations ◽  
European Respiratory Society ◽  
Black Adults ◽  
Technical Requirements ◽  
Reference Equations ◽  
Predicted Values ◽  
Never Smokers ◽  
Lower Limits ◽  
White Adults

ABSTRACT Objective: To derive reference equations for spirometry in healthy Black adult never smokers in Brazil, comparing them with those published in 2007 for White adults in the country. Methods: The examinations followed the standards recommended by the Brazilian Thoracic Association, and the spirometers employed met the technical requirements set forth in the guidelines of the American Thoracic Society/European Respiratory Society. The lower limits were defined as the 5th percentile of the residuals. Results: Reference equations and limits were derived from a sample of 120 men and 124 women, inhabitants of eight Brazilian cities, all of whom were evaluated with a flow spirometer. The predicted values for FVC, FEV1, FEV1/FVC ratio, and PEF were better described by linear equations, whereas the flows were better described by logarithmic equations. The FEV1 and FVC reference values derived for Black adults were significantly lower than were those previously derived for White adults, regardless of gender. Conclusions: The fact that the predicted spirometry values derived for the population of Black adults in Brazil were lower than those previously derived for White adults in the country justifies the use of an equation specific to the former population.

Within- and between-day variability of respiratory impedance, using impulse oscillometry in adolescent asthmatics

2002 ◽  
Vol 34 (4) ◽  
pp. 312-319 ◽  
Author(s):  
Michael D. Goldman ◽  
Rick Carter ◽  
Robert Klein ◽  
Greg Fritz ◽  
Brian Carter ◽  
...  
Keyword(s):  
Respiratory Impedance ◽  
Impulse Oscillometry

Determination of lesion specific reference equations for respiratory function in individuals with spinal cord injury

2015 ◽  
Author(s):  
Anja M. Raab ◽  
Sonja De Groot ◽  
Marcel W.M. Post ◽  
David J. Berlowitz ◽  
Jacinthe Adriaansen ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Respiratory Function ◽  
Specific Reference ◽  
Cord Injury ◽  
Reference Equations

Total respiratory impedance by impulse oscillometry (IO) in patients with pulmonary tuberculosis (PT)

2016 ◽  
Author(s):  
Larisa Kiryukhina ◽  
Olga Volodich ◽  
Pavel Gavrilov ◽  
Leonid Mikhailov ◽  
Liudmila Archakova ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Respiratory Impedance ◽  
Impulse Oscillometry

Analysis of Aerodynamic Characteristics in the Bottom of a Car

2013 ◽  
Vol 373-375 ◽  
pp. 20-23
Author(s):  
Hai Tao Bao ◽  
Cheng Wang
Keyword(s):  
Numerical Simulation ◽  
Velocity Field ◽  
Pressure Field ◽  
Final Analysis ◽  
Aerodynamic Characteristics ◽  
Specific Reference ◽  
Computational Results ◽  
The Future ◽  
Cfd Method

The aerodynamic characteristics of ordinary vehicle have been studied by lots of scholars, while few people pay enough attention to the aerodynamic characteristics in the bottom of the car. As the requirements of regulations for the performance of the car continues to increase, Analysis of Aerodynamic Characteristics of the car is much more necessary now. In this paper , by using CFD method and getting benefit from the established CFD software, we gave external velocity field and pressure field of the car. The data was analyzed and summarized and the computational results are obtained. In the final analysis for the flatness in the bottom of the car influence on aerodynamic characteristics.This paper has done some useful attempts, and it will provide specific reference significance to the numerical simulation on design of the car in the future.

scholarly journals Measurement of Iris Thickness at Different Regions in Healthy Chinese Adults

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Qingchen Li ◽  
Yuan Zong ◽  
Huiming Wen ◽  
Jian Yu ◽  
Changbo Zhou ◽  
...  
Keyword(s):  
Anterior Segment ◽  
Final Analysis ◽  
Middle Part ◽  
Chinese Adults ◽  
Swept Source ◽  
Significant Difference ◽  
The Mean ◽  
Healthy Chinese ◽  
And Gender ◽  
The Right

Purpose. To study the variation of iris thicknesses in different regions and explore the possible correlations with age and gender. Methods. Healthy Chinese adults were recruited; the anterior segment of their eyes was imaged by swept-source optical coherence tomography (SS-OCT). The horizontal scan of the right eye was selected, and the thicknesses of both the nasal and temporal irises were measured at 199 evenly spaced points. Results. A total of 233 subjects with an average age of 36.79 ± 10.04 years (range 19 to 62) were included in the final analysis. The mean iris thicknesses of the temporal and nasal sides were 364.79 ± 47.58 μm and 372.44 ± 43.75 μm, respectively. The mean nasal iris thickness was positively correlated with age (β = 0.9 μm/year; P  = 0.002), but the temporal one was not (β = 0.077 μm/year; P  = 0.806). At 139 points of the nasal iris and 146 points of the temporal iris, the iris thickness was significantly correlated with age ( P  < 0.05). The thicknesses of the peripheral and pupillary parts were positively correlated with age, while the middle part was negatively correlated with age. No significant difference was observed in the mean iris thickness between genders (temporal: t = 1.597, P  = 0.112; nasal: t = 1.870, P  = 0.063), but females had a thicker iris than males at 50 points in the temporal side and 49 points in the nasal side ( P  < 0.05); no point in males was observed to have thicker iris compared to females. Conclusion. Using SS-OCT and the novel method, thicknesses of the iris at different regions were measured. The thicknesses of the peripheral and pupillary irises increase with age, while the thicknesses of the middle part decrease.

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