scholarly journals Trigeminal Herpes Zoster: Case Report

2021 ◽  
Vol 10 (9) ◽  
pp. 1378-1381
Author(s):  
Marcos André Killner ◽  
Fernanda Noguez Sum ◽  
Rafaela Savio Melzer ◽  
Cintia Mussi Milani
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Trigeminal Nerve ◽  
Dorsal Root ◽  
Diabetes Patient ◽  
Cell Mediated Immunity ◽  
Varicella Zoster ◽  
Laboratory Confirmation ◽  
Increased Risk ◽  
Pain Symptoms

Herpes Zoster is an acute, self-limiting, viral infection caused by the reactivation of the Varicella Zoster Virus (VZV) that remains latent in the dorsal root ganglion. It commonly affects the older people and immunocompromised individuals. Diabetes patients present an increased risk for Herpes Zoster due to their impaired cell-mediated immunity.  Clinically it manifests with tingling, pruritus and painful vesicular eruptions along the affected nerve. The most commonly affected dermatomes are the thoracic and lumbar; trigeminal nerve can be involved and the ophtalmic nerve is the mostly affected. The diagnosis is based on clinical examination and laboratory confirmation. Treatment consists of antiviral therapy and is indicated to reduce acute pain symptoms, limit the spread and duration of the lesions, and prevent complications. The objective of the present study was to present a case report of Herpes Zoster involving the first and second division of the trigeminal nerve, in a 55 year old, male, diabetes patient.

scholarly journals Reactivation of Varicella Zoster Virus after Vaccination for SARS-CoV-2

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 572
Author(s):  
Mina Psichogiou ◽  
Michael Samarkos ◽  
Nikolaos Mikos ◽  
Angelos Hatzakis
Keyword(s):  
Adverse Event ◽  
Herpes Zoster ◽  
T Cell ◽  
Varicella Zoster Virus ◽  
Time Window ◽  
Vaccine Safety ◽  
Cell Mediated Immunity ◽  
Varicella Zoster ◽  
Increased Risk ◽  
Immunocompetent Patients

Seven immunocompetent patients aged > 50 years old presented with herpes zoster (HZ) infection in a median of 9 days (range 7–20) after vaccination against SARS-CoV-2. The occurrence of HZ within the time window 1–21 days after vaccination defined for increased risk and the reported T cell-mediated immunity involvement suggest that COVID-19 vaccination is a probable cause of HZ. These cases support the importance of continuing assessment of vaccine safety during the ongoing massive vaccination for the COVID-19 pandemic and encourage reporting and communication of any vaccination-associated adverse event.

scholarly journals Orofacial Herpes Zoster Infection in Dental practice: A Case Report

2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Deepa Gurung ◽  
Ujjwal Joshi ◽  
Bikash Chaudhary
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Trigeminal Nerve ◽  
Maculopapular Rash ◽  
Dental Practice ◽  
Herpes Zoster Infection ◽  
Prodromal Symptoms ◽  
Varicella Zoster ◽  
Burning Pain ◽  
Ophthalmic Branch

Herpes zoster infection, commonly known as Shingles, is caused by reactivation of the Varicella-Zoster virus which may have remained latent in the dorsal root ganglia. HZI is characterized by prodromal symptoms of unilateral deep aching, burning pain followed by a maculopapular rash, vesicular eruptions, ulcers, and scab formations over the affected nerve distribution. The ophthalmic branch of the trigeminal nerve is more commonly involved in HZI than maxillary and mandibular branches; in particular, the maxillary involvement is rare. This is a case report of HZI in a 65-years-old male patient involving the maxillary division of the trigeminal nerve. This case highlights the importance of early diagnosis and prompt use of antivirals in managing orofacial HZI in dental practice.

scholarly journals Disseminated Herpes Zoster in a Patient with Acute Lymphoblastic Leukaemia: A case study

2018 ◽  
Vol 44 (1) ◽  
pp. 60-63 ◽  
Author(s):  
Md Salahuddin Shah ◽  
Masuda Begum ◽  
Mujahida Rahman ◽  
Saqi Md Abdul Baqi
Keyword(s):  
Herpes Zoster ◽  
Dorsal Root ◽  
Rare Case ◽  
Lymphocytic Leukemia ◽  
Limited Area ◽  
Cell Mediated Immunity ◽  
Transplant Recipients ◽  
Varicella Zoster ◽  
Vesicular Rash

Varicella zoster virus (VZV) is a member of Herpesviridae family. It can cause two distinct clinical entities: varicella (chickenpox) and herpes zoster (shingles).1,2Herpes Zoster(HZ) is painful, vesicular rash in a limited area on one side of body due to the reactivation of latent VZV in dorsal root ganglia.Involvement of three or more dermatomes is known as disseminated zoster and seen in immunocompromised individuals.It can occur at any age. The risk of herpes zoster increases with old age and in patients with reduced cell mediated immunity such as haematological malignancies, immunosuppressive therapies, HIV infection and transplant recipients. The incidence of herpes zoster has been variably reported as 2% in Chronic myeloid leukaemia (CML), 13% in Chronic lymphocytic leukemia(CLL) and 30% in transplantrecipients.3-5This was a rare case of disseminated herpes zoster in a patient with Acute Lymphoblastic Leukaemiadeveloped while on chemotherapy progressing to prolonged myelosuppression.Bangladesh Med Res Counc Bull 2018; 44(1):59-61

scholarly journals Herpes zoster in the radial nerve distribution in an 8 years old healthy child-a case report

2017 ◽  
Vol 5 (3) ◽  
pp. 1123
Author(s):  
Hala Edris ◽  
Abdullah Abualiat ◽  
Ayed Al Mordy
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Radial Nerve ◽  
Dorsal Root ◽  
Primary Infection ◽  
The Body ◽  
Varicella Zoster ◽  
Chicken Pox ◽  
Nerve Ganglion ◽  
Common Area

Varicella zoster is an omnipresent virus which commonly affects childhood as chicken pox. Although the primary infection is self-limiting and seldom severe, the virus remains dormant in the body. The virus resides in the dorsal root or cranial nerve ganglion and reactivation may occur years later as herpes zoster or "Shingles". Herpes zoster (HZ) can occur at any age but is rare in childhood and adolescents. Old aged and immunosuppressed subjects are at risk for developing the disease. The most common area involved in HZ is the trunk (dermatomes innervated by the thoracic nerves) and rarely presents exclusively in the upper extremity. We report a case of HZ isolated to the radial nerve distribution in a healthy 8 years boy. The reported case reveals the importance of considering zoster infection in young age, or uncommon sites when evaluating the onset of pain in a dermatomal distribution specially if associated with vesiculobullous rash.

ACUTE MANAGEMENT OF VISARPA (HERPES ZOSTER): A CASE REPORT

2021 ◽  
Vol 12 (4) ◽  
pp. 1-3
Author(s):  
Ashwini K Sori ◽  
Ravishankar Pervaje
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Dorsal Root ◽  
Neck Region ◽  
Burning Sensation ◽  
Treatment Modalities ◽  
Varicella Zoster ◽  
Oral Medications ◽  
State Present ◽  
Good Improvement

Herpes zoster (Visarpa) is infection that results in the formation of painful red skin rashes due to reactivation of Varicella-Zoster Virus from its latent state present in a posterior dorsal root ganglion. The worldwide incidence of Herpes Zoster is 5-10% per 100 populations. In our ancient classics of Ayurveda, the diseased mentioned as visarpa resembles herpes zoster which is mentioned apart from Kushtha vyadhis. The attributes to acute symptoms like an utana shopha, daha, jwara, vedana and the nature of sphotas / pidikas are so specific that it is described as agnidagdhavat. The management of disease in contemporary system is though only symptomatic done with antiviral drugs. The description of management of Visarpa with different treatment modalities is available in the classical literatures of Ayurveda having promising results, so here is a case report of a female patient presenting with lesions over the neck region with itching, fever and burning sensation, Dhara, lepa, mridu shodhana was given along with oral medications by the end of 5 days treatment patient showed good improvement in symptoms.

scholarly journals Herpes zoster recurrence within 1 month: A case report

2021 ◽  
Vol 19 ◽  
pp. 205873922110212
Author(s):  
Nan Zhao ◽  
Yulan Geng ◽  
Yexian Li ◽  
Lijuan Liu ◽  
Yanjia Li ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Case Report ◽  
Herpes Zoster ◽  
B Cells ◽  
Varicella Zoster Virus ◽  
Lower Limit ◽  
Skin Disease ◽  
Clinical Manifestations ◽  
Varicella Zoster ◽  
Humoral Immune

Herpes zoster (HZ), caused by the varicella-zoster virus, is an infectious skin disease that rarely recurs after initial presentation. The mechanism underlying HZ recurrence is currently under investigation. In this article, we report a case of HZ relapse within 1 month. Analysis of patient’s clinical manifestations, histopathological features, and flow cytometry results indicated that the absolute and percentage values of B cells were below the lower limit. We hypothesized that the patient had abnormal humoral immune function, which may be one reason leading to the HZ relapse within 1 month. The findings of this case will serve as useful reference for HZ recurrence for clinicians. This case was impactful and added to the literature on HZ recurrence.

Herpes Zoster with Cutaneous Dissemination in a Patient 21 Years after Splenectomy for Idiopathic Thrombocytopenic Purpura

2012 ◽  
Vol 16 (5) ◽  
pp. 368-371 ◽  
Author(s):  
Rachel A. Moquete ◽  
Barry Hartman ◽  
Richard D. Granstein
Keyword(s):  
Herpes Zoster ◽  
Herpes Simplex ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Good Health ◽  
Immunocompetent Patient ◽  
Thrombocytopenic Purpura ◽  
Virus Family ◽  
Varicella Zoster ◽  
Increased Risk ◽  
History Of

Background: Varicella-zoster virus is a member of the herpes virus family that causes varicella during a primary infection and herpes zoster (HZ) when reactivated. Patients who are immunocompromised often have atypical presentations of HZ and experience complications such as multidermal involvement and dissemination. Objective: We report a case of disseminated HZ in an immunocompetent patient with a history of splenectomy for idiopathic thrombocytopenic purpura (ITP). Our 46-year-old female patient presented with a painful vesiculopapular dermatomal rash with approximately 80 other lesions diffusely spread over her body. She was in good health but had a splenectomy for ITP 21 years earlier and a history of recurrent herpes labialis. The latter led to the tentative diagnosis of a widespread herpes simplex infection. However, laboratory results confirmed a diagnosis of disseminated herpes zoster. A workup of the patient's immune status did not reveal any abnormalities other than the patient's previously noted splenectomy. Conclusions: This case adds to the two reports of patients developing cutaneous disseminated HZ several years after splenectomy. Our case serves as a reminder that patients with a history of splenectomy appear to be at increased risk for cutaneous dissemination of HZ. Renseignements de base: Le virus varicelle-zona est un virus de la famille des Herpesviridae qui cause la varicelle durant une primo-infection, et l'herpès zoster (zona) (HZ) en cas de réactivation. Les patients qui sont immunocompromis ont souvent des présentations atypiques de HZ et affichent des complications telles que la participation et la dissémination multicutanées. Objectif: Nous exposons un cas de zona disséminé chez un patient immunocompétent ayant subi une splénectomie pour traiter un purpura thrombocytopénique idiopathique (PTI). Notre patiente âgée de 46 ans présentait une éruption vésiculo-papuleuse douloureuse localisée dans une zone dermatome avec environ 80 autres lésions diffuses réparties sur son corps. Elle était en bonne santé mais avait subi une splénectomie pour traiter un PTI 21 ans plus tôt et présentait des antécédents d'épisodes récurrents d'herpès labial. Ce dernier a abouti 'a un diagnostic provisoire d'une infection généralisée par le virus herpès simplex. Cependant, les résultats des analyses de laboratoire ont confirmé un diagnostic d'herpès zoster (zona) disséminé. Une investigation de l'état immunitaire de la patiente n'a pas révélé d'anomalies autres que la splénectomie que la patiente a subie antérieurement. Conclusions: Ce cas vient s'ajouter aux deux cas de patients signalés qui ont développé un HZ disséminé plusieurs années après avoir subi une splénectomie. Notre cas sert à rappeler que les patients présentant des antécédents de splénectomie semblent être exposés à un risque accru de dissémination cutanée sous forme de HZ.

scholarly journals Prevention of Post-herpetic Neuralgia from Dream to Reality: A Ten-step Model

2017 ◽  
Vol 2 (20;2) ◽  
pp. E209-E220 ◽  
Author(s):  
Mohamed Younis Makharita
Keyword(s):  
Herpes Zoster ◽  
Dorsal Root ◽  
Risk Groups ◽  
Substantial Effect ◽  
Viral Reactivation ◽  
Post Herpetic Neuralgia ◽  
Suggested Approach ◽  
Varicella Zoster ◽  
Acute Herpes Zoster ◽  
Step Model

Herpes zoster (HZ) is a painful, blistering skin eruption in a dermatomal distribution caused by reactivation of a latent varicella zoster virus in the dorsal root ganglia (DRG). Post-herpetic neuralgia (PHN) is the most common complication of acute herpes zoster (AHZ). Severe prodrome, greater acute pain and dermatomal injury, and the density of the eruption are the risk factors and predictors for developing PHN. PHN has a substantial effect on the quality of life; many patients develop severe physical, occupational, social, and psychosocial disabilities as a result of the unceasing pain. The long-term suffering and the limited efficacy of the currently available medications can lead to drug dependency, hopelessness, depression, and even suicide. Family and society are also affected regarding cost and lost productivity. The pathophysiology of PHN remains unclear. Viral reactivation in the dorsal root ganglion and its spread through the affected nerve result in severe ganglionitis and neuritis, which induce a profound sympathetic stimulation and vasoconstriction of the endoneural arterioles, which decreases the blood flow in the intraneural capillary bed resulting in nerve ischemia. Our rationale is based on previous studies which have postulated that the early interventions could reduce repetitive painful stimuli and prevent vasospasm of the endoneural arterioles during the acute phase of HZ. Hence, they might attenuate the central sensitization, prevent the ischemic nerve damage, and finally account for PHN prevention. The author introduces a new Ten-step Model for the prevention of PHN. The idea of this newly suggested approach is to increase the awareness of the health care team and the community about the nature of HZ and its complications, especially in the high-risk groups. Besides, it emphasizes the importance of the prompt antiviral therapy and the early sympathetic blockades for preventing PHN. Key words: Acute herpes zoster, prevention, post-herpetic neuralgia, sympathetic blockade, tenstep model

scholarly journals A Novel Case of Resolved Postherpetic Neuralgia with Subsequent Development of Trigeminal Neuralgia: A Case Report and Review of the Literature

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Alexander Mason ◽  
Kristen Ayres ◽  
Sigita Burneikiene ◽  
Alan T. Villavicencio ◽  
E. Lee Nelson ◽  
...  
Keyword(s):  
Case Report ◽  
Herpes Zoster ◽  
Trigeminal Neuralgia ◽  
Female Patient ◽  
Trigeminal Nerve ◽  
Postherpetic Neuralgia ◽  
Subsequent Development ◽  
Review Of The Literature ◽  
Trigeminal Pain ◽  
Ophthalmic Branch

A 72-year-old female patient is presented, who was diagnosed with herpes zoster along the left ophthalmic branch of the trigeminal nerve with associated cutaneous vesicles. The patient subsequently developed postherpetic neuralgia in the same dermatome, which, after remission, transformed into paroxysmal trigeminal pain. The two different symptom sets, with the former consistent with PHN and the later consistent with trigeminal neuralgia, were unique to our practice and the literature.

scholarly journals Herpes Zoster in Kidney Transplant Recipients: A Series of Three Cases

2020 ◽  
Vol 10 (3) ◽  
pp. 139-146 ◽  
Author(s):  
Ramy M. Hanna ◽  
Farid Abd-El-Malak ◽  
Ammar Alnaser ◽  
Rumi Cader ◽  
Julie M. Yabu
Keyword(s):  
Herpes Zoster ◽  
Kidney Transplant ◽  
Clinical Course ◽  
Clinical Manifestations ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Varicella Zoster ◽  
Organ Rejection ◽  
Increased Risk ◽  
Disseminated Disease

Kidney transplant recipients require lifelong immunosuppression to prevent organ rejection. The need for this intervention, however, leads to decreased cellular immunity and, in turn, increased risk of developing herpes zoster (HZ) from reactivation of latent varicella zoster virus. HZ commonly presents as a painful rash in a dermatome presentation followed by post-herpetic neuralgia. In immunosuppressed individuals, the presentation can be atypical and vary in severity depending on degree of immunosuppression and host immune response. We present the clinical course of 3 kidney transplant recipients who developed HZ after transplantation at different times post-transplant with varying clinical manifestations. The balance between maintaining immunosuppression and preventing or subsequently treating disseminated disease is discussed.

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