scholarly journals Comparative Evaluation of Immunohistochemical Expression of Estrogen Receptor, Progesterone Receptor and HER2 in Fine Needle Aspiration Cell Blocks and Surgical Biopsies in Primary Breast Carcinoma

2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Megha Bansal ◽  
Permeet Kaur Bagga ◽  
Sumitoj Singh ◽  
Surinder Paul
Keyword(s):  
Estrogen Receptor ◽  
Breast Carcinoma ◽  
Progesterone Receptor ◽  
Fine Needle Aspiration ◽  
Comparative Evaluation ◽  
Needle Aspiration ◽  
Primary Breast Carcinoma ◽  
Immunohistochemical Expression ◽  
Fine Needle

Adenocarcinoma of mammary-like glands in the vulva successfully treated by weekly paclitaxel

2005 ◽  
Vol 15 (3) ◽  
pp. 568-571 ◽  
Author(s):  
H. Tanaka ◽  
T. Umekawa ◽  
K. Nagao ◽  
A. Ishihara ◽  
N. Toyoda
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Needle Aspiration ◽  
Weekly Paclitaxel ◽  
Axillary Lymph ◽  
Primary Breast Carcinoma ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

An 87-year-old was referred for gynecologic evaluation of a lesion involving the left labia majus noted 3 years earlier. Fine-needle aspiration cytology revealed clusters with an acinous structure or glandular formation. The tumor appeared as cell clusters with linear arrangements. Histologic examination showed the same morphologic findings as scirrhus type of primary breast carcinoma. Examinations of the breasts and axillary lymph nodes were normal. This disease was diagnosed as an adenocarcinoma arising in mammary-like glands of the vulva. Bone scan showed multiple foci in the sternum, costa, and vertebrae, consistent with metastatic disease. We administered five courses of weekly paclitaxel chemotherapy, which achieved a partial response. There were no severe adverse effects. In our case, the fine-needle aspiration cytology was a rapid and minimally invasive method of diagnosis, and the findings were extremely similar to those of the scirrhus type of primary breast carcinoma. Rapid and accurate diagnosis made with this technique might contribute to a good prognosis in the early-staged cases. Weekly paclitaxel chemotherapy may be one of the safe and effective treatments for this disease with distant metastases, even in extremely aged patients (over 80 years).

Fine-Needle Aspiration Biopsy Management of the Axilla in Primary Breast Carcinoma

2019 ◽  
Vol 63 (4) ◽  
pp. 314-318 ◽  
Author(s):  
Ciara Ellen Gibbons ◽  
Cecily Mary Quinn ◽  
David Gibbons
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Aspiration Biopsy ◽  
Primary Breast Carcinoma ◽  
Fine Needle ◽  
Acosog Z0011 ◽  
Needle Aspiration Biopsy ◽  
American Society

Context: Fine-needle aspiration biopsy (FNAB) is frequently used to stage the axilla preoperatively in patients with primary breast carcinoma. In the light of the ACOSOG-Z0011 and AMAROS trials that specified sentinel lymph node biopsy as an inclusion criterion, the role of FNAB in axillary staging is changing. Objective: This article will review the diagnostic accuracy of FNAB in staging of the axilla in patients with primary breast carcinoma. The efficacy of axillary FNAB compared with core-needle biopsy will be evaluated. The evolving approach to staging of the axilla, in the light of ACOSOG-Z0011 and AMAROS trials, will be discussed. Data Sources: Data were sourced from published peer-reviewed articles in PubMed (US National Library of Medicine) and published guidelines including the European Guidelines for Quality Assurance in Breast Cancer and those from the European Society of Medical Oncology (ESMO), Union for International Cancer (UICC), American Society of Clinical Oncology (ASCO), and the American Society of Breast Surgeons. Conclusions: FNAB of the axilla is almost 100% specific with a sensitivity between 40 and 90%. A positive FNAB reduces the need for a second axillary procedure by up to 20% with reduced morbidity and cost. The recent ACOSOG-Z0011 and AMAROS trials have reduced the use of FNAB axilla in American protocols, but it remains the standard of care in Europe.

Fine-needle aspiration technique for the concurrent immunocytochemical evaluation of multiple biologic parameters in primary breast carcinoma

1994 ◽  
Vol 32 (2) ◽  
pp. 221-228 ◽  
Author(s):  
Cecilia Bozzetti ◽  
Rita Nizzoli ◽  
Nadia Naldi ◽  
Laura Manotti ◽  
Luisa Savoldi ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Primary Breast Carcinoma ◽  
Fine Needle ◽  
Aspiration Technique

Mucinous breast carcinoma metastatic to parotid gland: Report of a case diagnosed by fine needle aspiration

Cytopathology ◽  
2018 ◽  
Vol 30 (1) ◽  
pp. 128-130 ◽  
Author(s):  
Radhika Agarwal ◽  
Deepika Rana ◽  
Latika Gupta ◽  
Meeta Singh ◽  
Shyama Jain ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Parotid Gland ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Fine Needle ◽  
Mucinous Breast Carcinoma

Correlation of Ultrasound Findings and Fine-Needle Aspiration Cytology for the Diagnosis of Axillary Lymph Node Metastasis in Patients with Breast Carcinoma

2018 ◽  
Vol 63 (1) ◽  
pp. 17-22
Author(s):  
Kusum Kapila ◽  
Preetha Alath ◽  
Govind H. Hebbar ◽  
Mohammed Jaragh ◽  
Sara S. George ◽  
...  
Keyword(s):  
Lymph Node ◽  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Width Ratio ◽  
Axillary Lymph ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Length Width ◽  
Needle Aspiration Cytology

Objective: Ultrasound-guided fine-needle aspiration cytology (USG-FNAC) is used for the detection of axillary lymph node (ALN) metastasis in patients with breast carcinoma (BC). US findings have a good diagnostic accuracy with high sensitivity and specificity. The aim of this study is to correlate the detection of ALN metastases on US with FNAC in BC patients. Study Design: In 75 BC patients, over a period of 9 months (January to September 2017), the size, cortical thickness (CT), presence or absence of hilar fat, and length/width ratio of ALN on US were reviewed and correlated with FNAC findings. Results: The age range was 29–78 (mean 52) years. There were 38 patients with a single ALN and 37 with multiple ALNs. ALNs with a maximum length of > 2.5 cm were malignant in 100% of cases while those ≥1.5 cm were malignant in 80.4%. ALNs with a CT of > 3 mm had metastasis in 78.1% cases. ALNs with absent hilar fat showed tumour in 87.5% cases. A length/width ratio of < 2 showed a metastatic tumour in 66.7% of aspirates. Conclusion: An association was seen between metastatic carcinoma on FNAC and axillary US features of a maximum length of ≥1.5 cm, the absence of hilar fat, and a CT of > 3 mm (p < 0.05).

Fine-Needle Aspiration Cytology in the Diagnosis of Breast Paraffinoma

2021 ◽  
pp. 1-5
Author(s):  
Kenneth Y.Y. Kok ◽  
Pemasiri Upali Telisinghe ◽  
Sonal Tripathi
Keyword(s):  
Breast Carcinoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Diagnostic Procedures ◽  
Giant Cells ◽  
Needle Aspiration ◽  
Multinucleated Giant Cells ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

<b><i>Introduction:</i></b> Paraffin injections for breast augmentation once a popular form of mammoplasty are now considered obsolete. It had been abandoned by clinicians because of its associated serious complications. The practice is however still available and is being practiced by nonmedically qualified people. Paraffin injection results in the formation of multiple foreign-body granulomas known as breast paraffinoma. The clinical features of breast paraffinoma can mimic and be mistaken for breast carcinoma or inflammatory breast carcinoma. The use of fine-needle aspiration cytology (FNAC) in the evaluation of patients with breast paraffinoma has not been fully evaluated. <b><i>Methods:</i></b> Retrospective review was performed on 30 patients who presented with breast paraffinoma between June 1, 2010, and June 30, 2020, who also had FNAC as part of their breast lump evaluation. <b><i>Results:</i></b> FNAC of 73.3% patients showed multinucleated giant cells and macrophages or histiocytes containing engulfed clear, empty intracytoplasmic vacuoles of varying sizes. In 13.3% of the patients, macrophages or histiocytes with engulfed clear intracytoplasmic vacuoles of varying sizes were seen. In 6.7% of patients, multinucleated giant cells containing engulfed vacuoles of varying sizes were seen, and in 6.7% of patients, hypocellular smears with large amount of clear spaces were seen. Oily droplets were seen in the background of all the smears, and there were no malignant cells seen. These features were compatible with breast paraffinoma. <b><i>Conclusion:</i></b> Most patients with breast paraffinoma can be managed conservatively and they do not require further treatment; FNAC with its characteristic features can provide the reliable diagnosis of breast paraffinoma and therefore sparing these patients from more invasive diagnostic procedures.

Sign in / Sign up

Export Citation Format

Share Document