scholarly journals Chronic obstructive pulmonary disease in organized groups

2020 ◽  
Vol 98 (6) ◽  
pp. 36-39
Author(s):  
G. T. Tаshmetovа ◽  
I. V. Liverko
Keyword(s):  
Risk Factors ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Toxic Substances ◽  
Upper Respiratory Tract ◽  
Obstructive Pulmonary Disease ◽  
Smoking Exposure ◽  
Upper Respiratory ◽  
Tract Infections

The objective: to study the prevalence of chronic obstructive pulmonary disease (COPD) in adult organized groups, to assess the structure and risk factors of its development.Subjects and methods. 3,000 people of the organized population working at various enterprises in Tashkent aged 20 to 60 years (1,400 (46.7%) women and 1,600 (53.3%) men) underwent the contemporary pulmonological screening.Results. The active pulmonological screening aimed to detect COPD among organized groups has been justified; examination of 3,000 people allowed detecting 198 (6.6%) new patients additionally to 65 cases that were already known at the time of screening. The chances of developing COPD increase with the presence of risk factors such as smoking, exposure to toxic substances and chemicals, and recurrent upper respiratory tract infections.

scholarly journals Molecular and clinical diseasome of comorbidities in exacerbated COPD patients

2015 ◽  
Vol 46 (4) ◽  
pp. 1001-1010 ◽  
Author(s):  
Rosa Faner ◽  
Alba Gutiérrez-Sacristán ◽  
Ady Castro-Acosta ◽  
Solène Grosdidier ◽  
Wenqi Gan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Vascular Tone ◽  
Molecular Mechanisms ◽  
Airflow Limitation ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients ◽  
Smoking Exposure

The frequent occurrence of comorbidities in patients with chronic obstructive pulmonary disease (COPD) suggests that they may share pathobiological processes and/or risk factors.To explore these possibilities we compared the clinical diseasome and the molecular diseasome of 5447 COPD patients hospitalised because of an exacerbation of the disease. The clinical diseasome is a network representation of the relationships between diseases, in which diseases are connected if they co-occur more than expected at random; in the molecular diseasome, diseases are linked if they share associated genes or interaction between proteins.The results showed that about half of the disease pairs identified in the clinical diseasome had a biological counterpart in the molecular diseasome, particularly those related to inflammation and vascular tone regulation. Interestingly, the clinical diseasome of these patients appears independent of age, cumulative smoking exposure or severity of airflow limitation.These results support the existence of shared molecular mechanisms among comorbidities in COPD.

RISK FACTORS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

1977 ◽  
Vol 105 (3) ◽  
pp. 223-232 ◽  
Author(s):  
BERNICE H. COHEN ◽  
WILMOT C. BALL ◽  
SHIRLEY BRASHEARS ◽  
EARL L. DIAMOND ◽  
PAUL KREISS ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease
Sign in / Sign up

Export Citation Format

Share Document