scholarly journals THEORETICAL SUBSTANTIATION OF DIRECT TRANSPORT OF BIOLOGICALLY ACTIVE COMPONENTS IN CONDITIONS OF MODELED GASTROINTESTINAL TRACT

Food systems ◽  
2018 ◽  
Vol 1 (2) ◽  
pp. 21-28
Author(s):  
A. V. Evteev ◽  
N. V. Gorbunova ◽  
O. S. Larionova ◽  
A. V. Bannikova
Keyword(s):  
Small Intestine ◽  
Biologically Active Compounds ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Active Components ◽  
Active Compounds ◽  
Theoretical Substantiation ◽  
Theoretical Approaches ◽  
Active Substances

In this paper, the results of studies on the release of biological active compounds from their encapsulated forms under conditions of enzymatic hydrolysis in vitro are presented. In the phase of the model «small intestine» swelling of the capsules and their subsequent decay occurs, which allows to speak about the controlled release of encapsulated bioactive components. It was revealed that almost 90 % of the residual quantity of essential ingredients was released from the capsules in the model phase of the artificial «small intestine». At the end of the experiment, the capsules released all the encapsulated biologically active substances, regardless of the content of fish oil and phenolic compounds in them. It was noted that the poly-capsules had the greatest propensity to withstand the aggressive environment of the «model stomach» and concentrate in themselves the maximum amount of biologically active substances. Mathematical modeling confirms the direct transport of biologically active compounds and the role of the swelling of capsules in the release of biologically active compounds. two mathematical models describing the classical theory of diffusion from capsules and incorporating the material relaxation coefficient demonstrate a combination of empirical and theoretical approaches in controlling the properties of encapsulated biologically active substances. the obtained data are promising in the field of development of improved and functional food products, as well as the dry ingredients and concentrates 

scholarly journals Research of biologically active compounds of catalpa (Catalpa bignonioides Walt.)

2020 ◽  
pp. 52-58
Author(s):  
O. V. Demeshko ◽  
S. V. Romanova ◽  
V. V. Kovalyov ◽  
I. I. Batiuchenko
Keyword(s):  
Acetic Acid ◽  
Phenolic Compounds ◽  
Chromatographic Analysis ◽  
Skin Diseases ◽  
Biologically Active Compounds ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Active Compounds ◽  
Chromatographic Paper ◽  
Active Substances

Catalpa bignonioides Walt. (catalpa) the family Bignoniaceae – a tree, which originates from North America. Catalpa bark contains resins and tannins. Monoterpene glycosides were found in the leaf. Catalpa seeds contain up to 30% of eleostearic acid. Decoctions are made of the bark of the tree. They serve as a gastric agent and have an anthelmintic effect. Decoction of the bark exhibits bronchodilator action, is used in the complex treatment of cancer. The leaves are used to treat skin diseases. The infusion of fruits has anti-herpetic and hypoglycemic properties. The aim of the work is to investigate biologically active compounds of the leaves of catalpa bignini. The object of the study was the leaves of common catalpa harvested in the summer of 2018 in Sevastopol. Chemical identification reactions and methods of chromatographic analysis were used to determine the major groups of biologically active substances of the leaves of the catalpa (chromatographic paper Filtrak FN No. 4, Munktell, Czech Republic). Chromatography was performed in pre-selected solvent systems: n-butanol‒acetic acid‒water (BAW) (4:1:2) ‒ I direction and 15% acetic acid ‒ II direction. Identification reactions were performed with aqueous and aqueous-alcoholic extracts of catalpa leaves. The qualitative composition of the phenolic compounds was investigated by paper chromatography. The content of the sum of phenolic compounds, hydroxycyclic acids and flavonoids was determined by the spectrophotometric method. Based on the held reactions and chromatographic analysis, by the characteristic fluorescence in the filtered UV light before and after treatment with chromogenic reagents and the values of Rf in the raw material the presence of the following groups of biologically active substances were determined: flavonoids, phenol glycosides, hydroxycoric acids. According to the chromatographic analysis, at least 9 substances of phenolic nature have been detected in the alcohol-aqueous extracts. For the first time, the presence of the following groups of biologically active substances: hydroxycoric acids, phenologic glycosides, flavonoids was determined in the leaves of catalpa. Quantitative content of natural compounds in the leaves of common catalpa: the sum of phenolic compounds (4,76 ± 0,04%), of hydroxycoric acids (3,42 ± 0,02%), of flavonoids (1,88 ± 0,02%). The results of the study will be used in the development of the draft quality control methods for medicinal plant raw materials.

scholarly journals INFLUENCE OF BIOTECHNOLOGICAL FACTORS ON THE YIELD OF BIOLOGICALLY ACTIVE COMPOUNDS FROM SORBUS AUCUPARIA

2021 ◽  
pp. 291-300
Author(s):  
Elena Nikolaevna Sokolova ◽  
Tat'yana Vladimirovna Yuraskina ◽  
Yuliya Aleksandrovna Borshcheva ◽  
Natal'ya Aleksandrovna Fursova ◽  
Anton Yur'yevich Sharikov ◽  
...  
Keyword(s):  
Amino Acids ◽  
Biologically Active Compounds ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Theoretical Research ◽  
Sorbus Aucuparia ◽  
Plant Materials ◽  
Active Compounds ◽  
Wide Range ◽  
Active Substances

Currently, the diet of almost all population groups in Russia is characterized by a deficiency of vitamins, essential amino acids, macro- and micronutrients, as well as biologically active substances (flavonoids, carotenoids, etc.). Replenishment of the lack of these components in the diet of the population due to natural sources of plant origin is an important and actual task of national health care. The rational use of natural components of plant materials containing a wide range of natural biologically active substances using biocatalytic methods, as well as the selection of optimal conditions for obtaining commodity forms of ingredients, will allow to create preventive products that have a beneficial effect on the human body. Theoretical research in the field of promising sources of food and biologically active ingredients among wild species of plant materials were carried out. Biomedical properties of Sorbus aucuparia were described. The technological characteristics of the biologically active substances extraction from dried plant raw materials was investigated. Thus, it was revealed that the degree of dried berries grinding about 0.2–0.8 mm, the hydromodule 1 : 10 and the extraction duration 240 minutes are most effective for the extractive substances yield. The enzymatic complex, allowing the maximum to release biologically valuable components to extract was selected. The amino acid composition of rowanberry with the use of high-performance liquid chromatography was investigated. Produced fermentalizates contain complex of biologically active compounds, including amino acids, vitamins, carotenoids, phenolic substances, that makes these ingredients promising for creation of various foodstuffs to improve quality, nutritional and biological value, taste and other consumer properties.

scholarly journals Extraction of biologically active compounds from the residues of pericarps of sugar beet (Beta vulgaris L. ssp. vulgaris)

2019 ◽  
Vol 25 ◽  
pp. 243-246
Author(s):  
O. L. Klyachenko ◽  
L. A. Janse ◽  
A. F. Likhanov
Keyword(s):  
Phenolic Compounds ◽  
Sugar Beet ◽  
Beta Vulgaris ◽  
Multicomponent System ◽  
Biologically Active Compounds ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Growth Promoters ◽  
Active Compounds ◽  
Active Substances

Aim. In the regulation of germination of seeds and of growth and development of seedlings, an important role belongs to biologically active substances that are found in the root of sugar beet (Beta vulgaris L. ssp. vulgaris), mainly in the pericarp. Extraction of secondary metabolites and study of the influence of a multicomponent system of endometabolites (phenolic compounds) of sugar beet pericarps on germination of plant seeds. Methods. The chemical composition of the metabolites of fruits and pericarps of sugar beet was determined by thin-layer chromatography; their differentiated isolation was carried out using column chromatography and gel filtration; The total content of phenolic compounds in fruits and pericarps was determined spectrophotometrically. Results. It was found that sugar beet pericarps contain a considerable amount of phenolic compounds (5-10 %). Four groups of phenolic compounds with different molecular masses were detected. By studying the influence of aquatic extracts on radish seeds, it was found that the eluents of the first volumes of water (3-5 ml) showed a pronounced stimulating effect, whereas further volumes of eluents (8-9 ml) were characterized by inhibitory action. Conclusions. Phenols, flavonoids and their glycosides were detected in extracts of sugar beet pericarps, which can be characterized as highly active inhibitors and growth promoters, therefore they could be used as natural biologically active substances. Keywords: sugar beet, pericarp, biologically active compounds, phenols, flavonoids.

scholarly journals Determination of the Qualitative Composition of Biologically Active Substances of Extracts of In Vitro Callus, Cell Suspension, and Root Cultures of the Medicinal Plant Rhaponticum carthamoides

2021 ◽  
Vol 11 (6) ◽  
pp. 2555
Author(s):  
Lyudmila Asyakina ◽  
Svetlana Ivanova ◽  
Alexander Prosekov ◽  
Lyubov Dyshlyuk ◽  
Evgeny Chupakhin ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Cell Suspension ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Root Cultures ◽  
Qualitative Composition ◽  
Callus Cell ◽  
Rhaponticum Carthamoides ◽  
Active Substances

This work aims to study the qualitative composition of biologically active substance (BAS) extracts in vitro callus, cell suspension, and root cultures of the medicinal plant Rhaponticum carthamoides. The research methodology is based on high-performance liquid chromatography, and 1H nuclear magnetic resonance (NMR) spectra, to study the qualitative and quantitative analysis of BAS. The results of the qualitative composition analysis of the dried biomass extracts of in vitro callus, cell suspension and root cultures showed that the main biologically active substances in the medicinal plant Rhaponticum carthamoides are 2-deoxy-5,20,26-trihydroxyecdyson (7 mg, yield 0.12%), 5,20,26-trihydroxyecdyson 20,22-acetonide (15 mg, yield 0.25%), 2-deoxy-5,20,26-trihydroxyecdyson 20,22-acetonide (6 mg, yield 0.10%), 20,26-dihydroxyecdyson 20,22-acetonidecdyson 20,22-acetonide (5 mg, yield 0.09%), and ecdyson 20,22-acetonide (6 mg, yield 0.10%). In the future, it is planned to study the antimicrobial, antioxidant, and antitumor activity of BAS of extracts of in vitro callus, cell suspension, and root cultures of the medicinal plant Rhaponticum carthamoides, for the production of pharmaceuticals and dietary supplements with antitumor, antimicrobial and antioxidant effects.

IN VITRO INVESTIGATION OF THE PERMEABILITY OF BIOLOGICALLY ACTIVE COMPOUNDS

2016 ◽  
Vol 33 (59) ◽  
pp. 41-45
Author(s):  
Tatyana A. Grigoreva ◽  
◽  
Aleksandr V. Garabadzhiu ◽  
Vyacheslav G. Tribulovich ◽  
◽  
...  
Keyword(s):  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds ◽  
In Vitro Investigation

scholarly journals Biologically active compounds from cyanobacteria extracts:in vivo and in vitro aspects

2013 ◽  
Vol 23 (3) ◽  
pp. 471-480 ◽  
Author(s):  
Luciana R. Carvalho ◽  
Adriana Costa-Neves ◽  
Geanne A.A. Conserva ◽  
Rafael L. Brunetti ◽  
Guilherme S. Hentschke ◽  
...  
Keyword(s):  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds
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