Протокол экспериментального исследования морфофункциональных свойств многослойной тканеинженерной конструкции желчного протока (Experimental Study of the Morphological and Functional Properties of the Bile Duct Multilayered Tissue-Engineering Construct)

2018 ◽  
Author(s):  
Ilya Klabukov
Keyword(s):  
Tissue Engineering ◽  
Experimental Study ◽  
Bile Duct ◽  
Functional Properties ◽  
Tissue Engineering Construct

scholarly journals Changes in Biliary Lipid Concentrations in Bile Duct Obstruction: An Experimental Study

1986 ◽  
Vol 79 (9) ◽  
pp. 522-527 ◽  
Author(s):  
Xu Guorong ◽  
C J C Kirk ◽  
A W Goode
Keyword(s):  
Experimental Study ◽  
Bile Duct ◽  
Bile Acids ◽  
Significant Role ◽  
Biliary Obstruction ◽  
Enterohepatic Circulation ◽  
Biliary Lipid ◽  
Complete Obstruction ◽  
Duct Obstruction ◽  
Biliary Lipids

Changes in biliary concentrations of bile acids, phospholipids and cholesterol and biliary pressures were measured in dogs. These parameters were studied during 7-day periods of partial biliary obstruction, of varying degrees, and after 24-hour and 48-hour periods of complete obstruction. The samples were obtained via an exteriorized but intact enterohepatic circulation allowing the introduction of varying degrees of obstruction and bile sampling. Biliary obstruction reduced the concentration of all biliary lipids especially when the obstruction produced pressures in excess of 75% of the maximum biliary secretion pressure. Only immediately after the release of a 48-hour period of complete obstruction did the risk of cholesterol supersaturation of bile occur. However, at that time there was a greatly reduced concentration of lipids in the bile and the amount of cholesterol that could potentially have precipitated was very small. It is suggested that this supersaturation would not play a significant role in the formation of gallstones.

scholarly journals Nanoengineering in Cardiac Regeneration: Looking Back and Going Forward

Nanomaterials ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 1587
Author(s):  
Caterina Cristallini ◽  
Emanuela Vitale ◽  
Claudia Giachino ◽  
Raffaella Rastaldo
Keyword(s):  
Tissue Engineering ◽  
Experimental Study ◽  
Extracellular Matrix ◽  
Regenerative Medicine ◽  
Cardiac Tissue ◽  
Cardiac Regeneration ◽  
Cardiac Cells ◽  
Integration Process ◽  
Specific Interest ◽  
Looking Back

To deliver on the promise of cardiac regeneration, an integration process between an emerging field, nanomedicine, and a more consolidated one, tissue engineering, has begun. Our work aims at summarizing some of the most relevant prevailing cases of nanotechnological approaches applied to tissue engineering with a specific interest in cardiac regenerative medicine, as well as delineating some of the most compelling forthcoming orientations. Specifically, this review starts with a brief statement on the relevant clinical need, and then debates how nanotechnology can be combined with tissue engineering in the scope of mimicking a complex tissue like the myocardium and its natural extracellular matrix (ECM). The interaction of relevant stem, precursor, and differentiated cardiac cells with nanoengineered scaffolds is thoroughly presented. Another correspondingly relevant area of experimental study enclosing both nanotechnology and cardiac regeneration, e.g., nanoparticle applications in cardiac tissue engineering, is also discussed.

Optimization of scaffold design for bone tissue engineering: A computational and experimental study

2014 ◽  
Vol 36 (4) ◽  
pp. 448-457 ◽  
Author(s):  
Marta R. Dias ◽  
José M. Guedes ◽  
Colleen L. Flanagan ◽  
Scott J. Hollister ◽  
Paulo R. Fernandes
Keyword(s):  
Tissue Engineering ◽  
Experimental Study ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Scaffold Design
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