From Prevention to Diagnosis and Treatment: Biomedical Applications of Metal Nanoparticle-Hydrogel Composites

2020 ◽  
Author(s):  
Aaron J. Clasky ◽  
Jeffrey D. Watchorn ◽  
Paul Chen ◽  
Frank Gu
Keyword(s):  
Biomedical Applications ◽  
Metal Nanoparticle ◽  
Diagnosis And Treatment ◽  
Hydrogel Composites

scholarly journals Graphene Integrated Hydrogels Based Biomaterials in Photothermal Biomedicine

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 906
Author(s):  
Le Minh Tu Phan ◽  
Thuy Anh Thu Vo ◽  
Thi Xoan Hoang ◽  
Sungbo Cho
Keyword(s):  
Photothermal Therapy ◽  
Biomedical Applications ◽  
High Light ◽  
Conversion Materials ◽  
Potential Applications ◽  
Good Biocompatibility ◽  
Biomedical Field ◽  
Hydrogel Composites ◽  
Material Fabrication ◽  
Biomedical Fields

Recently, photothermal therapy (PTT) has emerged as one of the most promising biomedical strategies for different areas in the biomedical field owing to its superior advantages, such as being noninvasive, target-specific and having fewer side effects. Graphene-based hydrogels (GGels), which have excellent mechanical and optical properties, high light-to-heat conversion efficiency and good biocompatibility, have been intensively exploited as potential photothermal conversion materials. This comprehensive review summarizes the current development of graphene-integrated hydrogel composites and their application in photothermal biomedicine. The latest advances in the synthesis strategies, unique properties and potential applications of photothermal-responsive GGel nanocomposites in biomedical fields are introduced in detail. This review aims to provide a better understanding of the current progress in GGel material fabrication, photothermal properties and potential PTT-based biomedical applications, thereby aiding in more research efforts to facilitate the further advancement of photothermal biomedicine.

Thermosensitive chitosan/phosphate hydrogel-composites fortified with Ag versus Ag@Pd for biomedical applications

Life Sciences ◽  
2018 ◽  
Vol 194 ◽  
pp. 185-195 ◽  
Author(s):  
Ghareib W. Ali ◽  
W. El-Hotaby ◽  
Bahaa Hemdan ◽  
Wafa I. Abdel-Fattah
Keyword(s):  
Biomedical Applications ◽  
Hydrogel Composites

scholarly journals Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

2019 ◽  
Vol 14 (3) ◽  
pp. 365-377 ◽  
Author(s):  
Jayshree Ashree ◽  
Qi Wang ◽  
Yimin Chao
Keyword(s):  
Quantum Dots ◽  
Cancer Detection ◽  
Cancer Diagnosis ◽  
Biomedical Applications ◽  
Biomedical Imaging ◽  
Recent Progress ◽  
Diagnosis And Treatment ◽  
Novel Approach ◽  
Behaviour Study

Abstract Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

scholarly journals Surface properties modulate protein corona formation and determine cellular uptake and cytotoxicity of silver nanoparticles

Nanoscale ◽  
2021 ◽  
Author(s):  
Marianna Barbalinardo ◽  
Jessika Bertacchini ◽  
Linda Bergamini ◽  
Maria Sara Magarò ◽  
Luca Ortolani ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Surface Properties ◽  
Cellular Uptake ◽  
Biomedical Applications ◽  
Protein Corona ◽  
Diagnosis And Treatment ◽  
Corona Formation ◽  
Basic Understanding

Nanoparticles (NPs) have been studied for biomedical applications, ranging from prevention, diagnosis and treatment of diseases. However, the lack of the basic understanding of how NPs interact with the biological...

scholarly journals MEMS Based Microneedles in the Field of Drug Delivery

2020 ◽  
Vol 9 (4) ◽  
pp. 2863-2867
Keyword(s):  
Drug Delivery ◽  
Human Skin ◽  
Biomedical Applications ◽  
Diagnosis And Treatment ◽  
New Devices

The technology of MEMS has paved way for many biomedical applications where a lot of new devices at microscale have emerged making the diagnosis and treatment of diseases more easy and efficient. Microneedles are one such example which have been used in drug delivery, vaccines as well and also in the field of cosmetology for skin treatments for scars, pigmentation, acne etc. Apart from penetration into the skin, the microneedles are also used in treating eye with some insertion of bioactives and also in the treatment of cells. The success of microneedles design and its application would depend solely on how it gets infused into the skin, skin recovery post the microneedle removal, how the drug stays stable during manufacturing and the delivery as well. Microneedle can pierce into the skin only when required amount of pressure is put for the insertion. This paper reviews on inception and the evolution of MEMS based microneedles and a microneedle is designed to show through the simulation that the force of 1.29N is required to break through the human skin for the reliable delivery of the drug.

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