scholarly journals Graphene Integrated Hydrogels Based Biomaterials in Photothermal Biomedicine

Nanomaterials ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 906
Author(s):  
Le Minh Tu Phan ◽  
Thuy Anh Thu Vo ◽  
Thi Xoan Hoang ◽  
Sungbo Cho

Recently, photothermal therapy (PTT) has emerged as one of the most promising biomedical strategies for different areas in the biomedical field owing to its superior advantages, such as being noninvasive, target-specific and having fewer side effects. Graphene-based hydrogels (GGels), which have excellent mechanical and optical properties, high light-to-heat conversion efficiency and good biocompatibility, have been intensively exploited as potential photothermal conversion materials. This comprehensive review summarizes the current development of graphene-integrated hydrogel composites and their application in photothermal biomedicine. The latest advances in the synthesis strategies, unique properties and potential applications of photothermal-responsive GGel nanocomposites in biomedical fields are introduced in detail. This review aims to provide a better understanding of the current progress in GGel material fabrication, photothermal properties and potential PTT-based biomedical applications, thereby aiding in more research efforts to facilitate the further advancement of photothermal biomedicine.

Nanomaterials ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 66 ◽  
Author(s):  
Thi Tuong Vy Phan ◽  
Thanh-Canh Huynh ◽  
Panchanathan Manivasagan ◽  
Sudip Mondal ◽  
Junghwan Oh

Palladium nanoparticles (PdNPs) have intrinsic features, such as brilliant catalytic, electronic, physical, mechanical, and optical properties, as well as diversity in shape and size. The initial researches proved that PdNPs have impressive potential for the development of novel photothermal agents, photoacoustic agents, antimicrobial/antitumor agents, gene/drug carriers, prodrug activators, and biosensors. However, very few studies have taken the benefit of the unique characteristics of PdNPs for applications in the biomedical field in comparison with other metals like gold, silver, or iron. Thus, this review aims to highlight the potential applications in the biomedical field of PdNPs. From that, the review provides the perceptual vision for the future development of PdNPs in this field.


2018 ◽  
Vol 16 (1) ◽  
pp. 92-99 ◽  
Author(s):  
Xiaoyan Zhang ◽  
Hailin Cong ◽  
Bing Yu ◽  
Qun Chen

Fullerenes, especially C60, exhibit great potential applications in biology field, due to their excellent antibacterial, antiviral, antitumor and other properties. Many water-soluble fullerene derivatives have been designed, synthesized and used as photo-dynamic therapy agents, antiviral agents, bioimaging agents, drug carriers and so on. This review focuses on the usage of water-soluble fullerene derivatives in biomedical field in recent years. The first half gives the preparation of water-soluble fullerene derivatives themselves with covalent bonds and non-covalent bonds. In the second half, myriad applications of water-soluble fullerene derivatives in biomedical field are introduced.


Inorganics ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 29
Author(s):  
Monica Pica ◽  
Roberto D’Amato

The present review aims to highlight the potential of an emerging 2D single element material: phosphorene. Attention is focused on the more recent studies on phosphorene, in terms of synthetic approaches, modification aimed at its stabilization, and potential applications in the biomedical field. Critical aspects for a practical use of phosphorene are discussed, in order to show a realistic scenario and challenges facing researchers.


Polymers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 2998 ◽  
Author(s):  
Moises Bustamante-Torres ◽  
David Romero-Fierro ◽  
Belén Arcentales-Vera ◽  
Samantha Pardo ◽  
Emilio Bucio

In recent years, polymer nanocomposites produced by combining nanofillers and a polymeric matrix are emerging as interesting materials. Polymeric composites have a wide range of applications due to the outstanding and enhanced properties that are obtained thanks to the introduction of nanoparticles. Therefore, understanding the filler-matrix relationship is an important factor in the continued growth of this scientific area and the development of new materials with desired properties and specific applications. Due to their performance in response to a magnetic field magnetic nanocomposites represent an important class of functional nanocomposites. Due to their properties, magnetic nanocomposites have found numerous applications in biomedical applications such as drug delivery, theranostics, etc. This article aims to provide an overview of the filler-polymeric matrix relationship, with a special focus on magnetic nanocomposites and their potential applications in the biomedical field.


2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Qiong-Qiong Ren ◽  
Ling-Yu Bai ◽  
Xiao-Shuai Zhang ◽  
Zhi-Ya Ma ◽  
Bo Liu ◽  
...  

Hollow gold nanospheres (HGNs) have great potential applications in biological sensing, biomedical imaging, photothermal therapy, and drug delivery due to their unique localized surface plasmon resonance (LSPR) feature, easy modification, good biocompatibility, and excellent photothermal conversion properties. In this review, the latest developments of HGNs in biosensing, bioimaging, photothermal therapy, and drug delivery are summarized, the synthesis methods, surface modification and bioconjugation of HGNs are also covered in this summary.


2019 ◽  
Vol 26 (38) ◽  
pp. 6834-6850 ◽  
Author(s):  
Mohammad Omaish Ansari ◽  
Kalamegam Gauthaman ◽  
Abdurahman Essa ◽  
Sidi A. Bencherif ◽  
Adnan Memic

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Beilei Gong ◽  
Yuanbing Shen ◽  
Huiyan Li ◽  
Xiaojun Li ◽  
Xia Huan ◽  
...  

AbstractOwing to strong and tunable surface plasmon resonance (SPR) effect and good biocompatibility, gold nanoparticles have been suggested to be a versatile platform for a broad range of biomedical applications. In this study, a new nanoplatform of thermo-responsive polymer encapsulated gold nanorods incorporating indocyanine green (ICG) was designed to couple the photothermal properties of gold nanorods (AuNRs) and the photodynamic properties of ICG to enhance the photodynamic/photothermal combination therapy (PDT/PTT). In addition to the significantly increased payload and enhancing photostability of ICG, the polymer shell in the nanoplatform also has thermo-responsive characteristics that can control the release of drugs at tumour sites upon the laser irradiation. On the basis of these improvements, the nanoplatform strongly increased drug aggregation at the tumour site and improved the photothermal/photodynamic therapeutic efficacy. These results suggest that this nanoplatform would be a great potential system for tumour imaging and antitumour therapy.


Materials ◽  
2021 ◽  
Vol 14 (7) ◽  
pp. 1631
Author(s):  
Mariangela Guastaferro ◽  
Ernesto Reverchon ◽  
Lucia Baldino

A comparative analysis concerning bio-based gels production, to be used for tissue regeneration, has been performed in this review. These gels are generally applied as scaffolds in the biomedical field, thanks to their morphology, low cytotoxicity, and high biocompatibility. Focusing on the time interval 2015–2020, the production of 3D scaffolds of alginate, chitosan and agarose, for skin and bone regeneration, has mainly been investigated. Traditional techniques are critically reviewed to understand their limitations and how supercritical CO2-assisted processes could overcome these drawbacks. In particular, even if freeze-drying represents the most widespread drying technique used to produce polysaccharide-based cryogels, supercritical CO2-assisted drying effectively allows preservation of the nanoporous aerogel structure and removes the organic solvent used for gel preparation. These characteristics are essential for cell adhesion and proliferation.


2021 ◽  
Author(s):  
Ao Tang ◽  
Ying Li ◽  
Yiqian Yao ◽  
Xuexia Yang ◽  
Zhangjun Cao ◽  
...  

Injectable hydrogels hold promise in biomedical applications due to their noninvasive administration procedure, and capacity enabling the filling of irregularly shaped defects. Protein-based hydrogels provide features including good biocompatibility and...


RSC Advances ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2253-2291
Author(s):  
Amin Shiralizadeh Dezfuli ◽  
Elmira Kohan ◽  
Sepand Tehrani Fateh ◽  
Neda Alimirzaei ◽  
Hamidreza Arzaghi ◽  
...  

Organic dots is a term used to represent materials including graphene quantum dots and carbon quantum dots because they rely on the presence of other atoms (O, H, and N) for their photoluminescence or fluorescence properties. Cargo delivery, bio-imaging, photodynamic therapy and photothermal therapy are major biomedical applications of organic dots.


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