International Review of Equity Market Structure Regulation: Phase III

2021 ◽  
Author(s):  
John Gulliver ◽  
Brian Johnson ◽  
Jon Ondrejko
Keyword(s):  
Market Structure ◽  
Equity Market ◽  
Phase Iii ◽  
International Review ◽  
Structure Regulation

scholarly journals Liquidity, Trading, and Price Determination in Equity Markets: A Finance Course Application

2021 ◽  
pp. 21-49
Author(s):  
Deniz Ozenbas ◽  
Michael S. Pagano ◽  
Robert A. Schwartz ◽  
Bruce W. Weber
Keyword(s):  
Market Structure ◽  
Price Discovery ◽  
Investment Decision ◽  
Equity Markets ◽  
Regulatory Environment ◽  
Trading Costs ◽  
Price Determination ◽  
Liquidity Trading ◽  
Portfolio Decision ◽  
Structure Regulation

AbstractTrading is the implementation of an investment decision. After a portfolio decision has been made by a portfolio manager, it must be implemented, and especially for handling large orders and navigating stressful markets, specific skills and responsibilities are needed that require the expertise of a professional trader. However, the efficiency with which orders are handled and turned into trades depends, not just on traders’ abilities, but also on a market’s liquidity, on the design of the marketplace where shares are traded, and on the regulatory environment. In this chapter, we cover trading costs, liquidity, volatility, price discovery, market structure, and market structure regulation.

scholarly journals Equity Market Structure Regulation: Time to Start Over

2021 ◽  
pp. 1
Author(s):  
Paul Mahoney
Keyword(s):  
Market Structure ◽  
Equity Market ◽  
Securities And Exchange Commission ◽  
Market Participants ◽  
The Past ◽  
Past Half Century ◽  
The Social ◽  
Private Incentives ◽  
Regulatory Mandates ◽  
Past Half

Over the past half-century, the U.S. Securities and Exchange Commission (SEC)’s regulations have become key determinants of the way in which stocks trade and the fees that exchanges charge for their services. The current equity market structure rules are contained primarily in the SEC’s Regulation NMS. The theory behind Regulation NMS is that a system of dispersed markets operating pursuant to SEC-mandated information and order routing links will provide the benefits of consolidation and competition simultaneously. This article argues that Regulation NMS has failed in that quest. It has produced fragmented markets and created questionable incentives for market participants, possibly producing socially excessive investments in trading speed and secrecy. It also discourages exchange innovation, provides insufficient incentives for traders to price orders aggressively, requires brokers to act against their customers’ interests, and forces the SEC to act as a price regulator. The article contends that the SEC should replace Regulation NMS with three simple design principles—issuer choice, exchange autonomy, and regulatory consistency. These would allow market forces, rather than regulatory mandates, to determine the design and pricing of trading platforms and the trading strategies of broker-dealers. They would better align the private incentives of trading platforms with the social objectives of improving liquidity and price discovery.

Volatility undercuts bitcoin’s effort to go mainstream

2021 ◽  
Keyword(s):  
Market Structure ◽  
Euro Area ◽  
Market Price ◽  
Central Banks ◽  
Equity Market ◽  
Bond Yields ◽  
Fiscal Stimulus ◽  
Content Type ◽  
Bubble Bursting ◽  
Dot Com

Significance Bitcoin is benefiting from the growing institutionalisation of the investor base for digital tokens, and the appeal of crypto-assets as a hedge against the debasement of currencies by money-printing central banks. Having reached an all-time high of USD41,823 on January 8, bitcoin, the world’s most widely traded cryptocurrency, has since lost nearly 20%. Impacts Wild price swings and the lack of a central market structure will limit bitcoin’s ability to challenge gold as a hedge against inflation. The S&P 500 equity market price-to-earnings ratio is near its highest since the 2000 dot-com crash, raising fears of the bubble bursting. The prospect of more aggressive US fiscal stimulus is driving a sell-off in treasuries, raising fears of a disorderly rise in bond yields. Europe’s COVID-19 resurgence raises the prospect of more stimulus, but also the scope for more tension about this among euro-area states.

RTS,S/AS01, a vaccine targeting pre-erythrocytic stages of Plasmodium falciparum

2017 ◽  
Vol 1 (6) ◽  
pp. 533-537
Author(s):  
Lorenz von Seidlein ◽  
Borimas Hanboonkunupakarn ◽  
Podjanee Jittmala ◽  
Sasithon Pukrittayakamee
Keyword(s):  
Protective Efficacy ◽  
Age Groups ◽  
Sub Saharan Africa ◽  
Phase Iii ◽  
European Medicines Agency ◽  
Older Children ◽  
Pivotal Phase ◽  
Malaria Epidemiology ◽  
Maximum Benefit ◽  
Sub Saharan

RTS,S/AS01 is the most advanced vaccine to prevent malaria. It is safe and moderately effective. A large pivotal phase III trial in over 15 000 young children in sub-Saharan Africa completed in 2014 showed that the vaccine could protect around one-third of children (aged 5–17 months) and one-fourth of infants (aged 6–12 weeks) from uncomplicated falciparum malaria. The European Medicines Agency approved licensing and programmatic roll-out of the RTSS vaccine in malaria endemic countries in sub-Saharan Africa. WHO is planning further studies in a large Malaria Vaccine Implementation Programme, in more than 400 000 young African children. With the changing malaria epidemiology in Africa resulting in older children at risk, alternative modes of employment are under evaluation, for example the use of RTS,S/AS01 in older children as part of seasonal malaria prophylaxis. Another strategy is combining mass drug administrations with mass vaccine campaigns for all age groups in regional malaria elimination campaigns. A phase II trial is ongoing to evaluate the safety and immunogenicity of the RTSS in combination with antimalarial drugs in Thailand. Such novel approaches aim to extract the maximum benefit from the well-documented, short-lasting protective efficacy of RTS,S/AS01.

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