scholarly journals What Do We Know About and What Could Be the Strategy Adopted to Treat Mucormycosis on Post-COVID-19 Cases? Is It an Adjuvant Nanomaterial?

2021 ◽  
Author(s):  
Gerson Nakazato ◽  
Wagner J Favaro ◽  
Nelson Duran

Unfortunately, Coronavirus disease 2019 (COVID-19) remains a significant public health issue worldwide, mainly in the USA, India and Brazil. The 2nd wave of COVID-19 has reached India first. The country has been making great effort to stabilize its current condition but, unfortunately, mucormycosis infection (or black fungus) associated with COVID-19 has emerged as another threat to the country and, most likely, to Brazil. It may have happened due to excessive glucocorticoid using, since the widespread administration of this drug can lead to secondary fungal infections. Mucormycosis is generated by a group of molds called mucormycetes; it is a rare, although likely fatal, contamination when patients are not properly treated. The concerning factor lies on the fact that the high COVID-19 incidence recorded in the first wave of it has increased even faster in its second wave in India; there have been some concerning cases in Brazil, as well. The current overview addresses the current therapies used to treat mucormycosis worldwide, as well as potential and new drugs for such a specific treatment. Anti-mucormycosis adjuvants and nanomaterials are the most interesting alternatives to treat patients with post-COVID-19 mucormycosis.

2009 ◽  
Vol 5 (5) ◽  
pp. 497-502 ◽  
Author(s):  
Amie Williams-Frame ◽  
Janet S Carpenter

Hot flashes are the cardinal symptom of menopause and can be treated with hormonal and nonhormonal prescription medications. However, considering that 6000 women enter menopause daily in the USA, and many of these women are symptomatic, the costs of these treatments can be a significant public health issue. We evaluated annual individual and population costs of hormonal and nonhormonal prescription treatments for hot flashes. Cost information may be helpful to clinicians and consumers in making treatment decisions.


2019 ◽  
Vol 3 (4) ◽  
pp. 250-252 ◽  
Author(s):  
David M Hille

ObjectiveTo identify changes in the linear trend of the age-standardized incidence of melanoma in Australia for all persons, males, and females. MethodsA two-piece piecewise linear regression was fitted to the data. The piecewise breakpoint varied through an iterative process to determine the model that best fits the data.ResultsStatistically significant changes in the trendof the age-standardized incidence of melanoma in Australia were found for all persons, males, and females. The optimal breakpoint for all persons and males was at 1998. For females, the optimal breakpoint was at 2005. The trend after these breakpoints was flatter than prior to the breakpoints, but still positive.ConclusionMelanoma is a significant public health issue in Australia. Overall incidence continues to increase. However, the rate at which the incidence is increasing appears to be decreasing.


2021 ◽  
Vol 15 ◽  
pp. 117863022110183
Author(s):  
Hamidreza Aghababaeian ◽  
Abbas Ostadtaghizadeh ◽  
Ali Ardalan ◽  
Ali Asgary ◽  
Mehry Akbary ◽  
...  

Background: Dust storms and their impacts on health are becoming a major public health issue. The current study examines the health impacts of dust storms around the world to provide an overview of this issue. Method: In this systematic review, 140 relevant and authoritative English articles on the impacts of dust storms on health (up to September 2019) were identified and extracted from 28 968 articles using valid keywords from various databases (PubMed, WOS, EMBASE, and Scopus) and multiple screening steps. Selected papers were then qualitatively examined and evaluated. Evaluation results were summarized using an Extraction Table. Results: The results of the study are divided into two parts: short and long-term impacts of dust storms. Short-term impacts include mortality, visitation, emergency medical dispatch, hospitalization, increased symptoms, and decreased pulmonary function. Long-term impacts include pregnancy, cognitive difficulties, and birth problems. Additionally, this study shows that dust storms have devastating impacts on health, affecting cardiovascular and respiratory health in particular. Conclusion: The findings of this study show that dust storms have significant public health impacts. More attention should be paid to these natural hazards to prepare for, respond to, and mitigate these hazardous events to reduce their negative health impacts. Registration: PROSPERO registration number CRD42018093325


2021 ◽  
Author(s):  

Gambling-related harms are increasingly recognised as a significant public health issue in Great Britain. The vast majority of those experiencing gambling harms remain unidentified and without support. Don't Bet Your Life On It (DBYLOI) blends lived experience and clinical expertise to deliver practical safer gambling strategies virtually for players that can be accessed anytime and anywhere to prevent any life from being needlessly affected by gambling-related harm. It is designed to support players at any level of play by providing players with a “seat belt” to prevent harms from occurring, identify early signs of risk, and signpost those experiencing harms to get the help they need. This theory of change visual and narrative considers the inputs, activities, outputs, and outcomes necessary to achieve these goals. It can be used by organizations, groups, and individuals in any sector impacted by gambling related harms in Great Britain.


2019 ◽  
Vol 37 (3) ◽  
pp. 124-129
Author(s):  
Safia Binte Rabbani ◽  
Pradip Ranjan Saha ◽  
Md Iqbal Hossain ◽  
Afsana Begum ◽  
Md Jahangir Talukder

Chikungunya is one of the most rapidly spreading Aedes mosquito-borne viral infectious diseases. Recently in Bangladesh it has emerged as an important public health issue. Chikungunya virus (CHIKV) mostly spread by Aedes aegypti and Aedes albopictus, an anthropophilic mosquito species widely distributed in Asia, Europe, Africa and America. Our objective was to determine the clinical, biochemical and radiological features of patients at the acute phase of CHIKV infection. The purpose of study was to evaluate the literature and summarize the current state of CHIKV-associated disease, including clinical presentation, diagnosis, risk factors for development of severe diseases, complications and treatment. We present 253 confirmed cases of chikungunya having different clinical presentations occurring among adult patients from different background including foreigner in Dhaka city, admitted in a tertiary level hospital situated in Gulshan from march’17 to November 2017 . All patients had fever and joint pain. Other common features were rash, diarrhoea, vomiting, confusion, and altered liver biochemistry. Adult patients with multiple co-morbidities admitted in hospital with male preponderance of 59 % and rest were female 41%. Most common complication was post CHIKV arthritis (79%) and rest of the less common complications were post viral asthenia (34%), myocarditis (27%), pneumonitis (30%). Dengue was excluded in all patients. Paracetamol remained the mainstay of treatment during febrile periods, but around 62% of the patients had prolonged joint symptoms requiring non-steroidal antiinflammatory drugs, colchicines, steroid. Among joint involvement, ankle joints were commonly involved joint presented with post viral arthritis. Since there is no specific treatment of chikungunya, prevention through vector control and public health education is the key. J Bangladesh Coll Phys Surg 2019; 37(3): 124-129


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
M Karakoç ◽  
Ö Erdoğan ◽  
E Demirbaş

Abstract Background Our study is intended to evaluate the Organizational Commitment of the Istanbul AFAD Search and Rescue Unit (AKB) employees operating at national and international level during disasters and to serve as a model for the other organizations that conduct national and international operations in the area of search and rescue. Methods This research was carried out with a total of 75 employees from Istanbul AFAD AKB from 02.11.18 to 01.01.2019. Introductory Information Form and Organizational Commitment Scale were used for data collection. Findings of the study were evaluated via IBM SPSS Statistics 22. Results Among 71 persons who participated in the study, it was determined that 91.5% were male, 50.7% were at the age of 40 or older, 81.7% were married, 67.6% had bachelor's degree, 63.4% were search and rescue technicians, and 50.7% were employed by their current organization for 10 years or less. Regarding the employees, it was found that 25.4% had very good organizational commitment while 54.9% faced issues in relation to the organizational commitment. OCS point average of the employees was 3.07±0.20 and the obtained Cronbach Alfa internal consistency coefficient of the scale was 0.678. OCS points of those employed for 12 years or longer in total were determined to be high at statistically significant level. Also, OCS points of those who did not face any issue in relation to the Organizational Commitment were found to be high at a statistically significant level against those who faced issues. Conclusions It is important to ensure work satisfaction, provide harmonization, and avert chaos and stress for boosting the organizational commitment. Therefore, the managers should conduct activities intended to boost the employee commitment levels within the organization. Key messages Disaster is a significant public health issue and disaster employees are special. The issues faced by the employees that perform search and rescue operations must be considered important and resolved.


2019 ◽  
Vol 46 (2_suppl) ◽  
pp. 90S-96S ◽  
Author(s):  
Kellie E. Carlyle ◽  
Jeanine P. D. Guidry ◽  
Sharyn A. Dougherty ◽  
Candace W. Burton

Social media platforms like Instagram are often used as venues for discussing relationships, making them ideal channels for promoting healthy relationships and preventing intimate partner violence (IPV). This is particularly relevant for IPV, which has been historically understood as a personal issue and lacked support for consideration as a significant public health issue. To explore a potential platform for IPV prevention, this study examines the ways in which IPV messages on Instagram reflect public health understandings of, and approaches to, prevention and how Instagram users engage with these posts. We analyzed 700 Instagram posts about IPV using the social ecological model as the theoretical framework for conceptualizing framing devices. Posts that mentioned individual causal attribution and individual solution responsibility were both present in the majority of posts and elicited more engagement than posts that did not. Encouragingly, the Instagram sample was more reflective of a range of different types of IPV experiences than previous analyses of traditional media content, possibly indicating that a public health approach to this issue is gaining traction.


2014 ◽  
Vol 42 (6) ◽  
pp. 1047-1056 ◽  
Author(s):  
Nualnong Wongtongkam ◽  
Andrew Day ◽  
Paul Russell Ward ◽  
Anthony Harold Winefield

Youth violence is a significant public health issue in Thailand where most people who are injured are vocational college students. There is a need to identify methods whereby such violence can be prevented. We trialed a group program in a technical college in Thailand with 23 students who received a modified version of aggression replacement training. We then compared their results with those of 24 students who did not receive any intervention or preintervention at 1 and 3 month followups. Although we found little evidence supporting the effectiveness of the intervention, participants in the intervention group suggested in the followup in-depth interviews that they felt more able to avoid or ignore provocation, and that they thought more about the consequences of aggressive behavior than they did prior to the intervention.


Author(s):  
Loren De Freitas ◽  
Han-I Wang

Introduction The COVID-19 pandemic has resulted in more than 35 million confirmed cases worldwide. Currently, there is no specific treatment for the disease or available vaccine to reduce the spread of COVID-19. As such, countries rely on a range of public health interventions to assist in halting the spread of transmission. Caribbean countries have also adopted many public health interventions. In this paper, we use mathematical modelling to demonstrate the impact of public health interventions on the progression of COVID-19 in order to provide timely decision support. Methods A cohort Markov model, based on the concept of the SEIR model, was built to reflect the characteristics of the COVID-19 virus. Five possible public health interventions in the first wave and a projection of current second wave were simulated using the constructed model. Results The model results indicate that the strictest combined interventions of complete border closure and lockdown were the most effective with the number of deaths less than ten in the first wave. For the current second wave, it will take around 30 days for the pandemic to pass its peak after implementing the wearing of face masks policy. Conclusions This paper shows the impact of common public health interventions on the COVID-19 pandemic, using Trinidad and Tobago as an example. Such impacts may be useful in reducing delays in decision-making and improving compliance by populations. However, given the limitations associated with mathematical models, decision-making should be guided by economic assessments, infectious disease and public health expertise.


2007 ◽  
Vol 31 (2) ◽  
pp. 211 ◽  
Author(s):  
Abdul Monaem ◽  
Micheal Woods ◽  
John Macdonald ◽  
Rodney Hughes ◽  
Michael Orchard

Men?s health is a significant public health issue in Australia. Increasingly, health indices show poor health outcomes for them. Literature suggests limitations in the health services dealing with their needs. If we are to improve boys? and men?s health, we should look at the efficacy of these services and address their limitations. This study provides data from a survey about the types of services available for boys and men. The service provider respondents expressed major concerns and identified ways of improving services.


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