scholarly journals Relationship between depression and lung function in the general population in Korea: a retrospective cross-sectional study

2018 ◽  
Vol Volume 13 ◽  
pp. 2207-2213 ◽  
Author(s):  
Youngmok Park ◽  
Ji Ye Jung ◽  
Young Sam Kim ◽  
Kyung Soo Chung ◽  
Joo Han Song ◽  
...  
Keyword(s):  
Lung Function ◽  
General Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Association of Serum Uric Acid with Lung Function in the National Health and Nutrition Examination Survey (NHANES), 2007-2012: A Cross-Sectional Study.

2021 ◽  
Author(s):  
Wen Luo ◽  
Wanyu Wang ◽  
Xiangyang Yao ◽  
Yonghong Shi ◽  
Fang Lu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Uric Acid ◽  
Lung Function ◽  
General Population ◽  
Serum Uric Acid ◽  
Cross Sectional Study ◽  
Nutrition Examination Survey ◽  
Sectional Study ◽  
Cross Sectional ◽  
Health And Nutrition

Abstract Background Evidence regarding the relationship between serum uric acid and lung function was controversial. Therefore, this study is designed to investigate whether serum uric acid was independently related to lung function in the National Health and Nutrition Examination Survey (NHANES) (2007-2012) after adjusting for other covariates. Methods The present study was a cross-sectional study. The total participants from NHANES (2007-2012) were 30442. After exclusion of subjects, 9474 subjects remained for the final analysis. The target independent variable and the dependent variable were serum uric acid measured at baseline and lung function respectively. Covariates involved in this study included age, sex, race, income-poverty ratio, body mass index, systolic blood pressure, diastolic blood pressure, blood urea nitrogen, cholesterol, creatinine, total protein, FeNO, calcium, alcohol drinking, smoke, phosphorus and total bilirubin. Results The average age of 9626 selected participants was 37.12 ± 16.03 years old, and about 49.19% of them were male. Result of fully adjusted linear regression showed serum uric acid was negatively associated with FEV1, FEV and PEF after adjusting confounders (Odds ratio (OR)= for FEV1 [-21.28 (-32.26, -10.30)], for FVC [-26.79 (-40.56, -13.01)] and for PEF [-72.19 (-101.93, -42.46)]). FEV1 and PEF were found a non-linear relationship with serum uric acid and the inflection points was 6.5mg/dl and 7.3 mg/dl respectively. The effect sizes and the confidence intervals in FEV1 and PEF of the left and right sides of inflection point were -11.50 (-25.55, 2.54) and -48.07 (-74.49, -21.66), -38.17 (-71.91, -4.43) and -311.11 (-427.28, -194.94) respectively. Conclusions We find serum uric acid was negatively associated with FEV1, FVC and PEF in a general population. Besides, there is a threshold effect on the independent association between serum uric acid and FEV1 and PEF. Those results are only found in the general population. Further epidemiologic studies will still be required to confirm this reverse association between serum uric acid and lung function.

Natural carcinogenic fiber and pleural plaques assessment in a general population: A cross-sectional study

2016 ◽  
Vol 150 ◽  
pp. 23-29 ◽  
Author(s):  
Caterina Ledda ◽  
Cristoforo Pomara ◽  
Massimo Bracci ◽  
Dario Mangano ◽  
Vincenzo Ricceri ◽  
...  
Keyword(s):  
General Population ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Pleural Plaques

scholarly journals Recurrent wheeze and its relationship with lung function and airway inflammation in preschool children: a cross-sectional study in South Korea

BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e018010 ◽  
Author(s):  
Ji Eun Soh ◽  
Kyung-Moon Kim ◽  
Ji-Won Kwon ◽  
Hyung Young Kim ◽  
Ju-Hee Seo ◽  
...  
Keyword(s):  
Preschool Children ◽  
Lung Function ◽  
Airway Inflammation ◽  
Allergic Diseases ◽  
Cross Sectional Study ◽  
Secondary Outcome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Airway Function ◽  
Recurrent Wheeze

BackgroundRelationship between recurrent wheeze and airway function and inflammation in preschool children is not fully known.ObjectiveTo investigate the relationship between recurrent wheeze and airway inflammation, lung function, airway hyper-reactivity (AHR) and atopy in preschool children.DesignObservational study, comparing forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and mid-forced expiratory flow (FEF25%–75%), dose–response slope (DRS), exhaled nitric oxide (eNO) and atopic sensitisation between children with recurrent wheeze and those without.SettingPopulation-based, cross-sectional study in Seoul and the Gyeonggi province of Korea conducted as a government-funded programme to perform standardised measurement of the prevalence of allergic diseases, and related factors, in preschool children.Participants900 children aged 4–6 years.Primary and secondary outcome measureseNO, FEV1/FVC, FEF25%–75%, DRS, atopic sensitisation and allergic diseases.MethodsChildren completed the modified International Study of Asthma and Allergies in Childhood questionnaire and underwent eNO assessments, spirometry, methacholine bronchial provocation tests and skin prick tests. Recurrent wheeze was defined as having a lifetime wheeze of more than three episodes, based on the questionnaire. The frequency of hospitalisation and emergency room visits was also obtained by means of the questionnaire. ‘Current’ wheeze was defined as having symptoms or treatments within the past 12 months.ResultsThe prevalence of recurrent wheeze was 13.4%. Children with recurrent wheeze showed a higher prevalence of lifetime or current allergic rhinitis (p=0.01 and p=0.002, respectively) and lifetime atopic dermatitis (p=0.007). Children with recurrent wheeze showed lower FEV1/FVC (p=0.033) and FEF25%–75%(p=0.004), and higher eNO levels (p=0.013) than those without recurrent wheeze. However, the DRS, prevalence of atopic sensitisation and serum IgE levels were not significantly different between the two groups.ConclusionsRecurrent wheeze in preschool children may be associated with airway inflammation and diminished airway function, but not with AHR or atopy.

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