scholarly journals Preparation Of Nanobubbles Modified With A Small-Molecule CXCR4 Antagonist For Targeted Drug Delivery To Tumors And Enhanced Ultrasound Molecular Imaging

2019 ◽  
Vol Volume 14 ◽  
pp. 9139-9157 ◽  
Author(s):  
Yanli Peng ◽  
Lianhua Zhu ◽  
Luofu Wang ◽  
Yu Liu ◽  
Kejing Fang ◽  
...  
Pharmaceutics ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1151
Author(s):  
Lu Tang ◽  
Jing Li ◽  
Qingqing Zhao ◽  
Ting Pan ◽  
Hui Zhong ◽  
...  

The encapsulation of therapeutic agents into nano-based drug delivery system for cancer treatment has received considerable attention in recent years. Advancements in nanotechnology provide an opportunity for efficient delivery of anticancer drugs. The unique properties of nanoparticles not only allow cancer-specific drug delivery by inherent passive targeting phenomena and adopting active targeting strategies, but also improve the pharmacokinetics and bioavailability of the loaded drugs, leading to enhanced therapeutic efficacy and safety compared to conventional treatment modalities. Small molecule drugs are the most widely used anticancer agents at present, while biological macromolecules, such as therapeutic antibodies, peptides and genes, have gained increasing attention. Therefore, this review focuses on the recent achievements of novel nano-encapsulation in targeted drug delivery. A comprehensive introduction of intelligent delivery strategies based on various nanocarriers to encapsulate small molecule chemotherapeutic drugs and biological macromolecule drugs in cancer treatment will also be highlighted.


Author(s):  
G.M. Lanza ◽  
P.M. Winter ◽  
S.D. Caruthers ◽  
M.S. Hughes ◽  
C.S. Hall ◽  
...  

2014 ◽  
Vol 1846 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Nunzia D'Onofrio ◽  
Michele Caraglia ◽  
Anna Grimaldi ◽  
Raffaele Marfella ◽  
Luigi Servillo ◽  
...  

2015 ◽  
Vol 16 (6) ◽  
pp. 542-548 ◽  
Author(s):  
Xibo Ma ◽  
Hui Hui ◽  
Wenting Shang ◽  
Xiaohua Jia ◽  
Xin Yang ◽  
...  

2002 ◽  
Vol 9 (2) ◽  
pp. S330-S331 ◽  
Author(s):  
Gregory M Lanza ◽  
Dana R Abendschein ◽  
Xin Yu ◽  
Patrick M Winter ◽  
Kerry K Karukstis ◽  
...  

2015 ◽  
Vol 21 (14) ◽  
pp. 1889-1898 ◽  
Author(s):  
Ji Yhee ◽  
Jangwook Lee ◽  
Hyeyoun Chang ◽  
Jeewon Lee ◽  
Ick Kwon ◽  
...  

2004 ◽  
Vol 5 (6) ◽  
pp. 495-507 ◽  
Author(s):  
Gregory Lanza ◽  
Patrick Winter ◽  
Shelton Caruthers ◽  
Anne Schmeider ◽  
Kathy Crowder ◽  
...  

2016 ◽  
Vol 7 (1) ◽  
pp. 728-736 ◽  
Author(s):  
Wantong Song ◽  
Zhaohui Tang ◽  
Dawei Zhang ◽  
Mingqiang Li ◽  
Jingkai Gu ◽  
...  

A tumor-targeted drug delivery system with small-molecule vascular disrupting agents inducing coagulation environment inside tumor and coagulation-targeted nanoparticles accumulating there.


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