SNP-SNP interactions within catechol-O-methyltransferase (COMT) gene influence sleep quality in subjects having chronic musculoskeletal pain-A Genetic Exploration ofMusculoskeletal Pain Study (GEMPS).

2016 ◽  
Vol 4 (7) ◽  
pp. 2270-2274
Author(s):  
Harjot Dhillon ◽  
◽  
Shallu Khullar ◽  
Gurpreet Kaur ◽  
Ritu Sharma ◽  
...  
2021 ◽  
Vol 10 (21) ◽  
pp. 4887
Author(s):  
Jani Mikkonen ◽  
Ville Leinonen ◽  
Hannu Luomajoki ◽  
Diego Kaski ◽  
Saana Kupari ◽  
...  

Reciprocal relationships between chronic musculoskeletal pain and various sleep disturbances are well established. The Pain and Sleep Questionnaire three-item index (PSQ-3) is a concise, valid, and reliable patient-reported outcome measure (PROM) that directly evaluates how sleep is affected by chronic low back pain (CLBP). Translation and cross-cultural validation of The Pain and Sleep Questionnaire three-item index Finnish version (PSQ-3-FI) were conducted according to established guidelines. The validation sample was 229 subjects, including 42 pain-free controls and 187 subjects with chronic musculoskeletal pain. Our aims were to evaluate internal consistency, test–retest reliability, measurement error, structural validity, convergent validity, and discriminative validity and, furthermore, to study the relationships between dizziness, postural control on a force plate, and objective sleep quality metrics and total PSQ-3-FI score. The PSQ-3-FI demonstrated good internal consistency, excellent test–retest reliability, and small measurement error. Confirmatory factor analysis confirmed acceptable fit indices to a one-factor model. Convergent validity indicated fair to good correlation with pain history and well-established pain-related PROMs. The PSQ-3-FI total score successfully distinguished between the groups with no pain, single-site pain, and multisite pain. A higher prevalence of dizziness, more impaired postural control, and a general trend towards poorer sleep quality were observed among subjects with higher PSQ-3-FI scores. Postural control instability was more evident in eyes-open tests. The Finnish PSQ-3 translation was successfully cross-culturally adapted and validated. The PSQ-3-FI appears to be a valid and reliable PROM for the Finnish-speaking CLBP population. More widespread implementation of PSQ-3 would lead to better understanding of the direct effects of pain on sleep.


2014 ◽  
Vol 11 (6) ◽  
pp. 574-579 ◽  
Author(s):  
Marianna Tsatali ◽  
Vasileios Papaliagkas ◽  
Dimitrios Damigos ◽  
Venetsanos Mavreas ◽  
Maria Gouva ◽  
...  

2021 ◽  
Vol 10 (6) ◽  
pp. 1247
Author(s):  
Gunilla M. Liedberg ◽  
Mathilda Björk ◽  
Elena Dragioti ◽  
Christina Turesson

Chronic musculoskeletal pain is a significant burden for employees, employers, and society. However, more knowledge is needed about which interventions reduce sick leave. Interventions were defined as the act or an instance of intervening, provided by different stakeholders. This review synthesizes the experiences of patients, employers, and health professionals concerning the interventions that influence returning to work and staying at work for persons with chronic musculoskeletal pain. A literature search was performed using several combinations of key terms. Overall, 18 qualitative studies published between 2002 and 2018 were included. Qualitative analysis assessed how much confidence could be placed in each review finding. Moderate evidence was found for factors improving the return to work process such as collaboration between stakeholders, including the persons with chronic musculoskeletal pain and support from all involved actors in the process. Moderate evidence was found for self-management strategies and workplace adjustments needed to facilitate more persons to returning to work and staying at work despite pain. This review provides stakeholders, employers, and health professionals’ information that could be used to develop and implement interventions to increase the possibilities for persons with chronic musculoskeletal pain returning to work or staying at work


Sign in / Sign up

Export Citation Format

Share Document