scholarly journals ASSOCIATION OF DENGUE VIRUS TYPE-SPECIFIC IGG ON PLATELETS IS SPECIFIC FOR THE ACUTE PHASE IN AN IMPORTED JAPANESE PATIENT WITH SECONDARY DENGUE 2 VIRUS INFECTION

2003 ◽  
Vol 31 (4) ◽  
pp. 223-225 ◽  
Author(s):  
KAZUNORI OISHI ◽  
SHINGO INOUE ◽  
TSUYOSHI KURAMOTO ◽  
SHOZABURO ONIZUKA ◽  
MARIKO SAITO ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Acute Phase ◽  
Virus Type ◽  
Japanese Patient ◽  
Specific Igg

scholarly journals Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection

Cell Reports ◽  
2020 ◽  
Vol 31 (4) ◽  
pp. 107569 ◽  
Author(s):  
Daniela Michlmayr ◽  
Eun-Young Kim ◽  
Adeeb H. Rahman ◽  
Rohit Raghunathan ◽  
Seunghee Kim-Schulze ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Acute Phase ◽  
Dengue Virus Infection

First Report of Dengue Virus Infection in a Bone Marrow Transplant Patient.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 5331-5331
Author(s):  
Myrna S. Figueroa ◽  
Luis A. Clavell
Keyword(s):  
Bone Marrow ◽  
Virus Infection ◽  
Dengue Virus ◽  
Bone Marrow Transplant ◽  
Virus Type ◽  
Transplant Patient ◽  
Marrow Transplant ◽  
Allogeneic Bone ◽  
Dengue Virus Infection ◽  
The World

Abstract Dengue virus infections are a frequent cause of morbidity and mortality in certain endemic areas of the world but it has never been reported to occur in a bone marrow transplant patient. We describe a pediatric patient with ALL on her first bone marrow relapse undergoing allogeneic bone marrow transplant who developed sepsis and irreversible shock that on postmortem autopsy proved to be secondary to dengue virus infection Type 4. A 6 years old female with ALL underwent an allogeneic bone marrow transplant from her sibling (6/6 match) on Nov 10, 1994. She received TBI (1200 rads) and ARA-C (3gm/m2 per dose per 12 doses) as preparative regimen. She developed generalized skin erythema on day +5 followed by fever on day +6. The following days were characterized by continued fever spikes, severe mucositis, persistence of the erythematous skin rash (first degree burn like) and gross hematuria in spite of broad spectrum antibiotic coverage. Blood cultures were reported negative. She developed irreversible shock and finally died on day +11 post-transplant. At autopsy (Nov 22, 1994), Dengue virus type 4 was isolated from blood, ascitic fluid, liver and spleen by routine viral culture at San Juan C.D.C. Dengue Branch. Results were confirmed by polymerase chain reaction. Her donor also developed low grade fever the day after bone marrow donation. Further blood testing on donor (Dec 2, 1994) showed positive IgM antibodies against Dengue virus Type 4. The recipient viral cultures matches with donor acute titers for Dengue Type 4, suggesting infection through bone marrow transplant. Dengue virus infection may cause significant morbidity and mortality to blood and bone marrow recipients in endemic areas of the world.

scholarly journals Specific IgM and IgG responses in primary and secondary dengue virus infections determined by enzyme-linked immunosorbent assay

2005 ◽  
Vol 134 (4) ◽  
pp. 820-825 ◽  
Author(s):  
A. SA-NGASANG ◽  
S. ANANTAPREECHA ◽  
A. A-NUEGOONPIPAT ◽  
S. CHANAMA ◽  
S. WIBULWATTANAKIJ ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Secondary Infection ◽  
Enzyme Linked Immunosorbent Assay ◽  
Virus Infections ◽  
Dengue Virus Infection ◽  
Provincial Hospital ◽  
Secondary Infections ◽  
Positive Rate ◽  
Specific Igg

IgM- and IgG-capture ELISAs are widely used as diagnostic tests for confirmation of dengue virus infection. The positive rate of anti-dengue IgM and IgG detection was examined in primary and secondary dengue virus infections in the setting of a provincial hospital using IgM- and IgG-capture ELISAs. Disease day 1 was defined as the day of onset of symptoms. In total, 232 plasma samples were collected from 106 confirmed dengue cases consisting of 12 primary and 94 secondary infections. In primary infection, anti-dengue IgM was detected in 4 out of 5 samples collected on disease day 5 and in all the 21 samples collected on disease day 6 or later. Specific IgG was detected in 2 out of 5 samples collected on day 12, and in 5 out of 6 samples collected on disease days 13–15, but was not detected in samples collected on disease day 10 or earlier. In secondary infection, IgM was not detected in the samples on disease days 2 and 3, but detected in 20 out of 79 samples collected on days 4–6, in 44 out of 65 on disease days 7–11 and in 40 out of 51 samples on disease days 12–14. In contrast, specific IgG was detected in 21 out of 60 samples on disease days 4 and 5, in 13 out of 19 on disease day 6, in 62 out of 65 on disease days 7–11 and in all the samples collected on disease day 12 or later. The result indicate that seroconversion rates of IgM and IgG are different between primary and secondary infections, and suggest that detection of specific IgM and IgG is necessary for determining dengue virus infection and for differentiating primary and secondary dengue infections.

scholarly journals Complete Genome Sequence of a Highly Divergent Dengue Virus Type 2 Strain, Imported into Australia from Sabah, Malaysia

2017 ◽  
Vol 5 (29) ◽  
Author(s):  
Alyssa T. Pyke ◽  
Bixing Huang ◽  
David Warrilow ◽  
Peter R. Moore ◽  
Jamie McMahon ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Female Patient ◽  
Genome Sequencing ◽  
Virus Type ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Dengue Virus Infection ◽  
Dengue Virus Type 2

ABSTRACT In 2015, a female patient returning to Australia from Sabah, Malaysia, was diagnosed with a suspected sylvatic dengue virus type 2 (DENV-2) infection, becoming the second case of imported highly divergent dengue virus infection recorded in Australia. We describe here the complete genome sequencing of the DENV-2 strain isolated from this patient.

scholarly journals Dynamics of cellular immune responses in the acute phase of dengue virus infection

2013 ◽  
Vol 158 (6) ◽  
pp. 1209-1220 ◽  
Author(s):  
Tomoyuki Yoshida ◽  
Tsutomu Omatsu ◽  
Akatsuki Saito ◽  
Yuko Katakai ◽  
Yuki Iwasaki ◽  
...  
Keyword(s):  
Virus Infection ◽  
Immune Responses ◽  
Dengue Virus ◽  
Acute Phase ◽  
Dengue Virus Infection ◽  
Cellular Immune Responses ◽  
Cellular Immune

Confirmation of dengue virus infection by detection of dengue virus type 1 genome in urine and saliva but not in plasma

2007 ◽  
Vol 101 (7) ◽  
pp. 738-739 ◽  
Author(s):  
Y. Mizuno ◽  
A. Kotaki ◽  
F. Harada ◽  
S. Tajima ◽  
I. Kurane ◽  
...  
Keyword(s):  
Virus Infection ◽  
Dengue Virus ◽  
Virus Type ◽  
Dengue Virus Infection

scholarly journals An outbreak of dengue virus (DENV) type 2 Cosmopolitan genotype in Israeli travellers returning from the Seychelles, April 2017

2017 ◽  
Vol 22 (26) ◽  
Author(s):  
Yaniv Lustig ◽  
Dana Wolf ◽  
Ora Halutz ◽  
Eli Schwartz
Keyword(s):  
Phylogenetic Analysis ◽  
Virus Infection ◽  
Dengue Virus ◽  
Virus Type ◽  
Dengue Virus Infection ◽  
Diagnostic Capabilities ◽  
Dengue Virus Type 2

Dengue virus infection was diagnosed in six Israeli travellers returning from the Seychelles in April 2017. Phylogenetic analysis identified identical sequences belonging to the Cosmopolitan genotype of dengue virus type 2 in all samples sequenced, thus providing evidence for a probable dengue type 2 outbreak in the Seychelles. This report further demonstrates the role of travellers as sentinels for arboviral infections, especially in countries with limited diagnostic capabilities.

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