Clinical manifestations and differential diagnosis of atopic dermatitis in young children

Atopic dermatitis is one of the most common dermatological diseases in infants and young children. The disease is characterized by a chronic recurrent course with itching, erythema, lichenification and desquamation. Typical cases are diagnosed on the clinically available diagnostic criteria. However, similar clinical manifestations are found in a number of other diseases that can simulate, accompany or complicate the course of atopic dermatitis. They include inflammatory skin conditions, infections, parasitic diseases, genodermatoses, immunodeficiencies and malignancies, as well as nutritional disorders, graft-versus-host disease, and drug disease. Knowledge of the spectrum of these diseases and their distinctive features is crucial for the correct and timely diagnosis of atopic dermatitis, the selection of the optimal treatment.

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Scoring atopic dermatitis in infants and young children: distinctive features of the SCORAD index

Allergy ◽

10.1111/j.1398-9995.2004.00622.x ◽

2005 ◽

Vol 60 (1) ◽

pp. 113-116 ◽

Cited By ~ 51

Author(s):

N. Pucci ◽

E. Novembre ◽

M. G. Cammarata ◽

R. Bernardini ◽

M. G. Monaco ◽

...

Keyword(s):

Atopic Dermatitis ◽

Young Children ◽

Distinctive Features ◽

Infants And Young Children

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Food Sensitization in Infants and Young Children with Atopic Dermatitis

Yonsei Medical Journal ◽

10.3349/ymj.2004.45.5.803 ◽

2004 ◽

Vol 45 (5) ◽

pp. 803 ◽

Cited By ~ 15

Author(s):

Dong Ki Han ◽

Myung Kwan Kim ◽

Jae Eun Yoo ◽

Sung Yon Choi ◽

Byoung Chul Kwon ◽

...

Keyword(s):

Atopic Dermatitis ◽

Young Children ◽

Food Sensitization ◽

Infants And Young Children

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The Sensitization of House Dust Mite(HDM) and Food Allergen of Atopic Dermatitis in Korean Infants and Young Children

Journal of Allergy and Clinical Immunology ◽

10.1016/j.jaci.2005.12.928 ◽

2006 ◽

Vol 117 (2) ◽

pp. S235

Author(s):

W. Seo

Keyword(s):

Atopic Dermatitis ◽

Young Children ◽

House Dust ◽

House Dust Mite ◽

Food Allergen ◽

Dust Mite ◽

Infants And Young Children

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Measuring Changes in Movement Skills with Infants and Young Children with Handicaps

Journal of the Association for Persons with Severe Handicaps ◽

10.1177/154079698601100301 ◽

1986 ◽

Vol 11 (3) ◽

pp. 153-161 ◽

Cited By ~ 9

Author(s):

Philippa H. Campbell ◽

Barbara Stewart

Keyword(s):

Young Children ◽

Intervention Program ◽

Baseline Assessment ◽

Early Intervention Program ◽

Functional Movement ◽

Age Limits ◽

And Performance ◽

Motor Milestone ◽

Infants And Young Children ◽

Selection Of

Posture and movement abilities are typically measured by assessments of achievements of motor milestone skills. Performance of a skill within appropriate chronological age limits is one dimension of posture and movement. Qualitative dimensions, including postural tone and the pattern of coordinated movement used in performance, are equally important with young children. This article describes a programmatic approach for measuring qualitative dimensions and performance of functional movement. Features of the approach include: (a) selection of intervention targets, (b) baseline assessment, (c) intervention sequences, (d) measurement, and (e) interpretation and decision making. Data that were collected, using this approach, with infants and young children enrolled in an early intervention program are presented to illustrate measurement and interpretation.

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Case Report: Prolapsed Ureterocele—A Differential Diagnosis of Urethral Cists

Case Reports in Urology ◽

10.1155/2020/2490129 ◽

2020 ◽

Vol 2020 ◽

pp. 1-3

Author(s):

Francisco Renan Doth Sales ◽

Georgia Alexsandra Colantonio Dourado ◽

Ana Carolina Montes Ribeiro ◽

Humberto de Holanda Madeira Barros ◽

David Sucupira Cristino ◽

...

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Urinary Tract ◽

Young Children ◽

Clinical Presentation ◽

Cystic Dilatation ◽

Distal Ureter ◽

Urethral Prolapse ◽

Infants And Young Children ◽

Vulvar Mass

Ureterocele is a cystic dilatation of submucosal distal ureter. It presents a higher incidence in infants and young children but is rare in adults. The urethral prolapse of ureterocele is extremely rare, and its clinical presentation includes vulvar mass, hematuria, and urinary tract dysfunction. We present a case of ureterocele prolapse in a 45-year-old woman who has a 3-day-evolution vulvar mass and intense urethral bleeding. The patient underwent armed cystoscopy and ureteroscopy, ureterocele resection, and biopsy. She evolved with good postoperative condition and was then discharged.

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PECULIARITIES OF CLINICAL PASSING OF ATOPIC DERMATITIS AND VITAMIN D EXCHANGE IN EARLY CHILDREN

Likarska sprava ◽

10.31640/jvd.3-4.2020(5) ◽

2020 ◽

pp. 27-35

Author(s):

N. V. Kamut ◽

M. M. Kiselova

Keyword(s):

Vitamin D ◽

Atopic Dermatitis ◽

Young Children ◽

Clinical Manifestations ◽

Serum Vitamin ◽

Scientific Data ◽

Main Group ◽

Severe Atopic Dermatitis ◽

Serum Vitamin D ◽

Vitamin D Levels

The article is devoted to the study of features of clinical course of atopic dermatitis and vitamin D exchange in young children conducted by us by estimation of severity of atopic dermatitis depending on the value of SCORAD index, determination of 25(OH)D concentration in serum of children by immunochemical method with chemocentric analysis according to the classification approved by experts of the international endocrinological society. In the examination of 188 young children, two groups were formed on the basis of the Lviv City Children's Clinical Hospital. Children from 1 month to 1 year of age with manifestations of atopic dermatitis (n = 120), who were born full-term and had no birth defects, metabolic disorders, severe perinatal CNS lesions formed the main group. The comparison group consisted of 68 healthy young children without chronic diseases. All children had atopic dermatitis in the main group and were classified by severity (depending on the SCORAD index): children with mild severity – 31 (26 %), moderate 47 (39 %), and severe 42 (35 %). As a result of the study, we found a association between the severity of clinical manifestations of atopic dermatitis and the level of vitamin D in the serum. Comparative analysis of the severity of atopic dermatitis, depending on the level of vitamin D in the serum, showed that with severe atopic dermatitis in children of the main group, the level of 25(OH)D was significantly lower compared to its indicators in children with moderate to severe (P < 0.05). Serum vitamin D levels are significantly lower in all forms of atopic dermatitis severity and correlate significantly with the overall SCORAD severity score, erythema intensity, excoriation, itching, and sleep disturbances. The scientific data on the presence of feedback correlation (r = –0,48; P < 0,05) between the development of atopic dermatitis in children and their level of 25(OH)D in serum were added. Our findings suggest that there is a need for a differentiated approach to treating early-stage atopic dermatitis of varying severity, a personalized therapeutic approach to choosing a vitamin D supplementation, given the level of 25(OH)D in the serum.

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Etiologies of Hospitalized Acute Bronchiolitis in Children 2 Years of Age and Younger: A 3 Years' Study During a Pertussis Epidemic

Frontiers in Pediatrics ◽

10.3389/fped.2021.621381 ◽

2021 ◽

Vol 9 ◽

Author(s):

Sainan Chen ◽

Yuqing Wang ◽

Anrong Li ◽

Wujun Jiang ◽

Qiuyan Xu ◽

...

Keyword(s):

Young Children ◽

Medical Records ◽

Clinical Presentation ◽

Leukocyte Count ◽

Clinical Manifestations ◽

Human Bocavirus ◽

Acute Bronchiolitis ◽

Laboratory Examination ◽

A Prospective Study ◽

Infants And Young Children

Objective: In recent years, the incidence of Bordetella pertussis infection in infants and young children has been increasing. Multiple studies have suggested that B. pertussis may be one of the pathogens of bronchiolitis in infants and young children. However, the prevalence and clinic characteristic of B. pertussis in bronchiolitis is controversial. This prospective descriptive study evaluated the prevalence and clinical manifestations of infants and young children hospitalized for bronchiolitis with B. pertussis.Methods: Children hospitalized with bronchiolitis were eligible for a prospective study for 36 months from January 1, 2017, to December 31, 2019. Besides B. pertussis, 10 common respiratory viruses and Mycoplasma pneumoniae (MP) were confirmed by laboratory tests. Medical records of patients were reviewed for demographic, clinical characteristics, and laboratory examination.Results: A total of 1,092 patients with bronchiolitis were admitted. B. pertussis was detected in 78/1,092 (7.1%) patients. Of the 78 patients with B. pertussis bronchiolitis, coinfections occurred in 45 (57.7%) patients, most frequently with human rhinovirus (28/78, 35.9%), followed by MP (9/78, 11.4%), and human bocavirus (6/78, 7.7%). The peak incidence of B. pertussis infection was in May. A high leukocyte count could help distinguish B. pertussis–associated acute bronchiolitis from other acute bronchiolitis etiologies. After excluding coinfections, children with B. pertussis–only bronchiolitis exhibited a milder clinical presentation than those with RSV-only infection; also, children with MP-only and other pathogen infections revealed similar severity. The morbidity of B. pertussis was common (31/78, 39.7%) in infants with bronchiolitis under 3 months.Conclusion: In summary, B. pertussis is one of the pathogens in children with bronchiolitis, and coinfection of B. pertussis with other viruses is common in bronchiolitis. B. pertussis should be considered when patients hospitalized with bronchiolitis present a longer course and have an elevated leukocyte count. Patients with B. pertussis–associated bronchiolitis present a milder clinical presentation.

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