scholarly journals Clinical manifestations of new coronavirus infection (COVID-19) in children admitted to hospital

Author(s):  
D. I. Sadykova ◽  
S. V. Khaliullina ◽  
V. A. Anokhin ◽  
A. I. Ziatdinov ◽  
S. A. Senek ◽  
...  

Objective. To describe clinical and laboratory features of COVID-19 in children admitted to the hospital.Children characteristics and research methods. The authors carried out a retrospective observational study, which included 204 children admitted to the Kazan hospital with a diagnosis of “new coronavirus infection” in the period from May 1 to October 30, 2020.Results. It was revealed that all hospitalized children had RNA of the SARS-CoV-2 virus (100%) in a smear from the nasopharynx and oropharynx detected by PCR and only 50% of patients were diagnosed with lung tissue lesions by computed tomography. The clinical picture of COVID-19 in children most often corresponds to the classic manifestations of a respiratory viral infection. Risk factors for the development of severe forms, described in adults, were recorded only in isolated cases in our study.Conclusion. The clinical picture of COVID-19 in children most often corresponds to the classic manifestations of a respiratory viral infection. Risk factors for the development of severe forms, described in adults, were recorded in isolated cases in our study.

2018 ◽  
Vol Volume 11 ◽  
pp. 861-872 ◽  
Author(s):  
Andrés Martín-Aspas ◽  
Francisca María Guerrero-Sánchez ◽  
Francisco García-Colchero ◽  
Sebastián Rodríguez-Roca ◽  
José-Antonio Girón-González

2020 ◽  
Vol 75 (5S) ◽  
pp. 378-385
Author(s):  
Natalia V. Orlova ◽  
Natalia D. Karseladze ◽  
Sergey A. Makhnev ◽  
Elena Y. Novikova ◽  
Yulia L. Latysheva ◽  
...  

Background. The new coronavirus infection COVID-19 has reached a pandemic in a few months. Large-scale measures have been taken to prevent the spread of infection, both in Russia and around the world. Analysis of the effectiveness of measures to prevent the spread of coronavirus infection COVID-19 is an urgent task to optimize the measures used to prevent the disease. Aims to identify infection risk factors, evaluate the effectiveness of the developed and implemented measures to prevent the spread of COVID-19 coronavirus infection at the airport of the Moscow Aviation Hub. Material and methods. Developed and implemented measures to prevent the spread of coronavirus infection COVID-19 on the territory of the airport complex, which is part of the Moscow Aviation Hub (UIA). An assessment of the incidence among employees was conducted, laboratory testing of airport employees for coronavirus infection COVID-19 was carried out: PCR for the detection of SARS-CoV-2 virus RNA; Anti-SARS-CoV-2 IgG. Conclusions. It was revealed that the complex of the developed measures has proven its effectiveness, made it possible to prevent the spread of infection among airport employees.


2019 ◽  
Vol 39 (4) ◽  
pp. 362-374 ◽  
Author(s):  
Marwh Aldriwesh ◽  
Noura Al-Dayan ◽  
Jonathan Barratt ◽  
Primrose Freestone

Background Infectious peritonitis is a clinically important condition contributing to the significant mortality and morbidity rates observed in peritoneal dialysis (PD) patients. Although some of the socioeconomic risk factors for PD-associated peritonitis have been identified, it is still unclear why certain patients are more susceptible than others to infection. Methods We examined the molecular components of human peritoneal dialysate (HPD) in an attempt to identify factors that might increase patient susceptibility to infection. Characterization studies were performed on initial and follow-up dialysate samples collected from 9 renal failure patients on PD. Results Our in vitro data showed that peritonitis-causing bacteria grew differently in the patient dialysates. Proteomic analysis identified an association between transferrin presence and infection risk, as peritoneal transferrin was discovered to be iron-saturated, which was in marked contrast to transferrin in blood. Further, use of radioactive iron-labeled transferrin showed peritoneal transferrin could act as a direct iron source for the growth of peritonitis-causing bacteria. We also found catecholamine stress hormones noradrenaline and adrenaline were present in the dialysates and were apparently involved in enhancing the growth of the bacteria via transferrin iron provision. This suggests the iron biology status of the PD patient may be a risk factor for development of infectious peritonitis Conclusions Collectively, our study suggests transferrin and catecholamines within peritoneal dialysate may be indicators of the potential for bacterial growth in HPD and, as infection risk factors, represent possible future targets for therapeutic manipulation.


2007 ◽  
Vol &NA; ◽  
pp. S248 ◽  
Author(s):  
Euijung Roh ◽  
Eunhee Chung ◽  
Youngpyo Chang ◽  
Woosung Park ◽  
Jaekyung Kim

Author(s):  
Konstantin Robertovich Gulyabin

There has been a recent obvious trend towards the increased prevalence of chronic rhinitis – 10-20% of the population experiences this disorder. Vasomotor rhinitis, sometimes also called idiopathic rhinitis, is the indisputable leader among various chronic rhinitis forms (allergic, infectious, atrophic, catarrhal and hypertrophic). The term of vasomotor rhinitis has been the subject of experts' repeated criticism because neurovisceral innervation disorders that underlie this condition are found in almost every form of chronic rhinitis. The main clinical manifestations of vasomotor rhinitis include a feeling of nasal congestion and nasal respiratory obstruction, regular abundant discharge of clear mucus and a feeling of its trickling down the posterior pharyngeal wall. A past respiratory viral infection treated by excessive quantities of vasoconstrictor drops triggers the vasomotor rhinitis onset in most cases.


Sign in / Sign up

Export Citation Format

Share Document