Comparative Study of the Possible Hepatoprotective Effect of Each of N-acetylcysteine, Coenzyme Q10 and Aloe Vera Gel in Acute Acetaminophen Induced Hepatotoxicity in Albino Rats. (Histological and Biochemical Study)

Diabetes is characterized by hyperglycaemia with alterations of lipid parameters. The effects of Aloe vera (A.V) gel extract on lipid profiles of streptozotocin-induced diabetic rats were investigated. Seventy-two male albino rats were randomly divided into six groups of 12 rats each; control, diabetic control, 4 ml/kg and 8 ml/kg body weight (b.w.) A.V, 10 mg/kg b.w. glibenclimide and non-diabetic 8 ml/kg b.w. A.V groups. They were treated for 14 and 28 days. The plasma and HDL lipid profiles (triacylglycerols, cholesterol and phospholipids) of the diabetic rats were significantly (p<0.05) increased, while those of the VLDL+LDL, RBC, RBC membrane and organs were observed to be significantly (p<0.05) reduced, when compared to the control after 14 and 28 days of treatment. A.V gel extract significantly (p<0.05) ameliorated the disruptions observed in the lipid profiles of the diabetic and thus provide a scientific rationale for the use of Aloe vera as a therapeutic agent.Bangladesh J Med Biochem 2016; 9(1): 11-26

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Ulcer protective action is improved by washing fresh Aloe vera gel: a comparative study with unwashed gel in indomethacin and ethanol induced ulcers in rats

International Journal of Pharmacology and Clinical Sciences ◽

10.5530/ijpcs.5.3.4 ◽

2016 ◽

Vol 5 (3) ◽

pp. 83-89

Author(s):

Jyoti Tara Manandhar Shrestha ◽

Roanak Shrestha ◽

Maya Shrestha ◽

Saurab Raj Joshi ◽

Merina Rajbhandari

Keyword(s):

Comparative Study ◽

Protective Action ◽

Aloe Vera ◽

Aloe Vera Gel

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Comparative Study on In vitro and In vivo Evaluation of Antioxidant Potential of Apple Peel Extract and Aloe Vera Gel

Journal of Food Processing and Preservation ◽

10.1111/jfpp.12639 ◽

2015 ◽

Vol 40 (4) ◽

pp. 607-614 ◽

Cited By ~ 3

Author(s):

Gauri Jairath ◽

Manish Kumar Chatli ◽

Ashim Kumar Biswas

Keyword(s):

Comparative Study ◽

Aloe Vera ◽

Antioxidant Potential ◽

In Vivo Evaluation ◽

Aloe Vera Gel ◽

Apple Peel ◽

Peel Extract

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EFFICACY OF ANTIOXIDANT WITH ALOE VERA GEL VERSUS INTRA-LESIONAL STEROIDS IN THE MANAGEMENT OF ORAL SUBMUCOUS FIBROSIS - A PROSPECTIVE COMPARATIVE STUDY

Pakistan Armed Forces Medical Journal ◽

10.51253/pafmj.v71isuppl-3.7921 ◽

2021 ◽

Vol 71 (Suppl-3) ◽

pp. S526-29

Author(s):

Muhammad Tahir ◽

Asim Abbas ◽

Faiz Ul Hassan Nawaz ◽

Mohsin Raza ◽

Atif Rafique ◽

...

Keyword(s):

Comparative Study ◽

Lipoic Acid ◽

Oral Submucous Fibrosis ◽

Aloe Vera ◽

Mouth Opening ◽

Burning Sensation ◽

Alpha Lipoic Acid ◽

Aloe Vera Gel ◽

Prospective Comparative Study ◽

Submucous Fibrosis

Objective: To compared efficacy of alpha lipoic acid (antioxidant medication) and aloe vera gel together versus intralesional steroids (hydrocortisone) in management of oral submucous fibrosis by evaluating post treatment clinical features of mouth opening and burning sensation. Study Design: A prospective comparative study. Place and Duration of Study: Department of ENT, Combined Military Hospital, Malir Karachi, from Jul 2018 to Mar 2020. Methodology: Twenty-eight patients were involved in the research and were distributed into two groups, I and II. Alpha lipoid acid with aloe vera gel was given in group I and hydrocortisone was given in group II. Burning sensation and mouth opening were recorded both at start and at monthly interval later on for three consecutive months. The data collected were statistically analyzed by using SPSS-22. Results: A significant lessening in burning sensation (p<0.001) and improvement in mouth opening were noticed in both groups. However, comparison between alpha lipoic acid with aloe vera gel group versus hydrocortisone group showed almost similar results. Conclusion: Alpha lipoic acid and aloe vera gel can significantly improve oral submucous fibrosis clinically. So, these can be utilized as an alternative option in cases where intralesional steroid is poorly tolerated or is contraindicated.

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