scholarly journals Genetic variation of myostatin MSTN gene and protein polymorphism in three goat populations

2021 ◽  
Vol 99 (3) ◽  
pp. 324-334
Author(s):  
Mohammed El-Sayed ◽  
Sam M.A. El-Hamamsy ◽  
Waled Abd-Elhamed ◽  
Mohamed El-Danasoury
Keyword(s):  
Genetic Variation ◽  
Protein Polymorphism ◽  
Mstn Gene

scholarly journals Genetic variation in the first intron and exon of the myostatin gene in several Indonesian cattle populations

2021 ◽  
pp. 1197-1201
Author(s):  
Peni Wahyu Prihandini ◽  
Almira Primasari ◽  
Aryogi Aryogi ◽  
Jauhari Efendy ◽  
Muchamad Luthfi ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Transforming Growth Factor ◽  
Association Studies ◽  
Negative Regulator ◽  
Reaction Products ◽  
Myostatin Gene ◽  
Mstn Gene ◽  
Synonymous Mutations ◽  
Intron 1 ◽  
Exon 1

Background and Aim: Myostatin (MSTN), a member of the transforming growth factor-β family, is a negative regulator of muscle mass. This study aimed to detect the genetic variation of the 1160 bp fragment of exon 1 and part of intron 1 of the MSTN gene in several cattle populations raised in Indonesia. Materials and Methods: Polymerase chain reaction products of the MSTN gene amplified from 92 animals representing 10 cattle populations (Peranakan Ongole [PO], Belgian Blue x PO cross, Rambon, PO x Bali cross, Jabres, Galekan, Sragen, Donggala, Madura, and Bali) were sequenced, compared, and aligned with bovine MSTN of Bos taurus (GenBank Acc. No. AF320998.1) and Bos indicus (GenBank Acc. No. AY794986.1). Results: Four nucleotide substitutions (nt 1045 and 1066 in intron 1; nt 262 and 418 in exon 1) and two indels (nt 807 and 869 in intron 1) were synonymous mutations. Among these substitutions, only the nt 262G>C and nt 418A>G loci were polymorphic in all populations, except Bali cattle. The frequencies of the nt 262C (0.82) and nt 418A (0.65) alleles were highest. For the nt 262G>C locus, the CC genotype had the highest frequency (0.66) followed by GC (0.30) and CC (0.03). For the nt 418A>G locus, the AG genotype had the highest frequency (0.52) followed by AA (0.39) and GG (0.09). Conclusion: The results, showing genetic variations in exon 1 and intron 1 of the MSTN gene, might be helpful for future association studies.

The Croonian Lecture, 1991. Genostasis and the limits to evolution

1991 ◽  
Vol 333 (1267) ◽  
pp. 289-305 ◽  
Keyword(s):  
Genetic Variation ◽  
Natural Selection ◽  
Good Evidence ◽  
Evolutionary Change ◽  
Protein Polymorphism ◽  
Practical Reasons ◽  
Rapid Evolutionary Change

The Darwinian explanation for evolution is that it is the outcome of the interaction between genetic variation and natural selection. There is now good evidence for both the existence of genetic variation and the occurrence of natural selection, the latter potentially at high intensities. The outcome should be rapid evolutionary change; yet in practice very little change is found. Most species are very stable, and in situations where evolution is observed in one species often none is found in others despite equivalent opportunity. Evolutionary failure is commonplace. Despite the occurrence of high levels of protein polymorphism, there is good evidence that the supply of variation making a major contribution to fitness is very limited. As a result it is argued that lack of evolution in most species may be due more to lack of appropriate variability than to other causes: a condition for which the term ‘ genostasis ’ is proposed. In those situations where appropriate genetic variation is available for one reason or another, evolution is found to be very rapid. There are good theoretical and practical reasons for more attention being paid to the mechanisms of supply of new variation and to those situations where evolution appears not to be taking place.

Genetic Variation in Tall Fescue (Festuca arundinaceaSchreb) Populations Based on Seed Storage Protein Polymorphism

2010 ◽  
Vol 11 (4) ◽  
pp. 390-398
Author(s):  
S. Afkar ◽  
G. Karimzadeh ◽  
A. A. Jafari
Keyword(s):  
Genetic Variation ◽  
Tall Fescue ◽  
Storage Protein ◽  
Seed Storage Protein ◽  
Seed Storage ◽  
Protein Polymorphism

scholarly journals Protein Polymorphism and Genetic Variation in a Population of the Japanese Quail

1980 ◽  
Vol 17 (6) ◽  
pp. 312-322 ◽  
Author(s):  
Masao KIMURA ◽  
Mototsugu ISHIGURO ◽  
Shin-ichi ITO ◽  
Iwahiro ISOGAI
Keyword(s):  
Genetic Variation ◽  
Japanese Quail ◽  
Protein Polymorphism

scholarly journals Blood group and protein polymorphism in the Finnish native cattle populations

1994 ◽  
Vol 3 (2) ◽  
pp. 169-176
Author(s):  
Juha Kantanen ◽  
Matti Ojala
Keyword(s):  
Genetic Diversity ◽  
Genetic Variation ◽  
Blood Group ◽  
Standard Method ◽  
Genetic Distances ◽  
Average Degree ◽  
Protein Polymorphism ◽  
Native Cattle ◽  
East And West ◽  
East West

Nine blood group loci and five polymorphic protein loci were investigated in the native East-, North- and West-Finnish cattle populations. The studied East-, North and West-Finnish cattle populations comprised 74, 55 and 121 individuals, respectively. According to the average degree of heterozygosity, East-Finnish cattle had the highest genetic variation and North-Finnish cattle the lowest. Within the loci investigated, the East- and North-Finnish cattle populations, which are threatened by extinction, did not lack genetic diversity. The genetic distances between West and North-Finnish cattle calculated by the Nei’s (1972) standard method ranged from 0.019 to 0.052 in three partly different locus groups and between East- and North-Finnish cattle from 0.034 to 0.046. The distances between East- and West- Finnish cattle were 0.030 in all cases. According to these results. East-, West- and North-Finnish cattle could be regarded as three different native breeds.

Labeled scales (e.g., category, Likert, VAS) and invalid across-group comparisons: What we have learned from genetic variation in taste.

2013 ◽  
Author(s):  
L. M. Bartoshuk ◽  
◽  
V. B. Duffy ◽  
K. Fast ◽  
B. G. Green ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Group Comparisons
Sign in / Sign up

Export Citation Format

Share Document