scholarly journals Do microvesicles derived from adipose mesenchymal stem cells have a therapeutic potential on Escherichia coli lipopolysaccharides-induced sepsis in Zona fasciculata of adult male albino rats? A histological study

2018 ◽  
Vol 41 (2) ◽  
pp. 204-219
Author(s):  
Abeer Omar ◽  
Alshaymaa Aboulkhair
Keyword(s):  
Escherichia Coli ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Adult Male ◽  
Therapeutic Potential ◽  
Histological Study ◽  
Albino Rats ◽  
Zona Fasciculata ◽  
Adipose Mesenchymal Stem Cells

The concurrent therapeutic potential of adipose-derived mesenchymal stem cells on Gentamycin-induced hepatorenal toxicity in rats

2021 ◽  
Vol 16 ◽  
Author(s):  
Mohamed A Rawash ◽  
Ayman Saber Mohamed ◽  
Emad M El-Zayat
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Uric Acid ◽  
Stem Cell ◽  
Kidney Disease ◽  
Therapeutic Potential ◽  
Daily Injection ◽  
Adipose Mesenchymal Stem Cells ◽  
Liver And Kidney ◽  
Therapy Option

Background: Adipose mesenchymal stem cells (AMSCs) are a type of stem cell employed to repair damaged organs. This study aimed to see how effective AMSCs are at treating gentamycin-induced hepatorenal damage in rats. Methods: 18 male Wister rats were assigned into three groups; control, Gentamycin (GM), and GM+AMSCs. GM induced hepatorenal toxicity through daily injection (100 mg/kg, i.p.) for eight days. On day 9, AMSC (106 cells/ml/rat) was injected intravenously. Results : Creatinine, urea, uric acid, AST, ALP, ALT, TNF-, and MDA levels decreased, whereas IL-10, GSH, and CAT levels increased, indicating the therapeutic potency of intravenous injection AMSCs. Conclusion: The current study demonstrated the simultaneous therapeutic efficacy of adipose mesenchymal stem cells on the liver and kidney in the treatment of Gentamycin-induced hepatotoxicity. These data show that AMSCs could be a feasible therapy option for liver and kidney disease.

The possible curative role of bone marrow-derived mesenchymal stem cells in bleomycin-induced skin changes in adult male albino rats

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Amal Abd-Elhafez ◽  
Maram Elkelany ◽  
Amany Mousa ◽  
Thorya El-deeb ◽  
Amira Kassab
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Adult Male ◽  
Albino Rats ◽  
Skin Changes
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