Association of Complete Blood Count Parameters with Gestational Diabetes Mellitus

Objective: The aim of this study is to evaluate the relationship between hematological changes in early pregnancy using complete blood count parameters and gestational diabetes mellitus. Study Design: One hundred pregnant with gestational diabetes mellitus and one hundred healthy pregnant were included in the study. Blood samples for routine complete blood count parameters in first trimester of pregnancy were analyzed. Results: In the gestational diabetes mellitus group white blood cell, platelet count, neutrophil and lymphocyte count, mean platelet volume, red cell distribution width were significantly higher than control group. However, there was no significant difference between groups with regard to neutrophil to lymphocyte ratio and platelet to lymphocyte ratio levels. In binary logistic regression analysis; first trimester mean platelet volume and red cell distribution width values were found to be independently associated with diagnosis of gestational diabetes mellitus. Conclusion: This study demonstrates that hematological parameters in first trimester of pregnancy are closely associated with gestational diabetes mellitus. The parameters that are routinely and automatically calculated in complete blood count; may be used to predict gestational diabetes mellitus.

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Can increased nuchal translucency in the first trimester of pregnancy predict gestational diabetes mellitus

Journal of Obstetrics and Gynaecology ◽

10.1080/01443610500231518 ◽

2005 ◽

Vol 25 (6) ◽

pp. 579-582 ◽

Cited By ~ 17

Author(s):

S. Kelekci ◽

B. Yilmaz ◽

K. Savan ◽

S. Sonmez

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

First Trimester ◽

Nuchal Translucency ◽

First Trimester Of Pregnancy ◽

Increased Nuchal Translucency

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Fasting plasma glucose and body mass index during the first trimester of pregnancy as predictors of gestational diabetes mellitus in a Chinese population

Endocrine Journal ◽

10.1507/endocrj.ej16-0359 ◽

2017 ◽

Vol 64 (5) ◽

pp. 561-569 ◽

Cited By ~ 10

Author(s):

Min Hao ◽

Li Lin

Keyword(s):

Diabetes Mellitus ◽

Body Mass Index ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Body Mass ◽

Plasma Glucose ◽

Fasting Plasma Glucose ◽

Chinese Population ◽

First Trimester ◽

First Trimester Of Pregnancy

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Role of mean platelet volume in pregnancy to predict gestational diabetes mellitus in the first trimester

The Journal of Maternal-Fetal & Neonatal Medicine ◽

10.1080/14767058.2019.1583730 ◽

2019 ◽

Vol 33 (21) ◽

pp. 3689-3694 ◽

Cited By ~ 3

Author(s):

Eser Colak ◽

Emel Ebru Ozcimen ◽

Mehmet Ufuk Ceran ◽

Yusuf Aytac Tohma ◽

Sevsen Kulaksızoglu

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Mean Platelet Volume ◽

First Trimester ◽

Platelet Volume ◽

In Pregnancy

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Criteria for Screening and Diagnosis of Gestational Diabetes Mellitus in the First Trimester of Pregnancy

Fetal Diagnosis and Therapy ◽

10.1159/000324684 ◽

2011 ◽

Vol 30 (2) ◽

pp. 108-115 ◽

Cited By ~ 19

Author(s):

Walter Plasencia ◽

Raquel Garcia ◽

Susana Pereira ◽

Ranjit Akolekar ◽

Kypros H. Nicolaides

Keyword(s):

Diabetes Mellitus ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

First Trimester ◽

First Trimester Of Pregnancy ◽

Screening And Diagnosis

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Lower Adiponectin Levels at First Trimester of Pregnancy Are Associated With Increased Insulin Resistance and Higher Risk of Developing Gestational Diabetes Mellitus

Diabetes Care ◽

10.2337/dc12-1731 ◽

2013 ◽

Vol 36 (6) ◽

pp. 1577-1583 ◽

Cited By ~ 67

Author(s):

M. Lacroix ◽

M.-C. Battista ◽

M. Doyon ◽

J. Menard ◽

J.-L. Ardilouze ◽

...

Keyword(s):

Diabetes Mellitus ◽

Insulin Resistance ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

First Trimester ◽

First Trimester Of Pregnancy

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The association of first trimester high blood pressure and risk of gestational diabetes mellitus

Arterial’naya Gipertenziya (Arterial Hypertension) ◽

10.18705/1607-419x-2012-18-1-67-72 ◽

2012 ◽

Vol 18 (1) ◽

pp. 67-72

Author(s):

P. V. Popova ◽

A. S. Gerasimov ◽

E. N. Kravchuk ◽

E. S. Shelepova ◽

E. M. Ryazantseva ◽

...

Keyword(s):

Diabetes Mellitus ◽

Blood Pressure ◽

Gestational Diabetes ◽

Gestational Diabetes Mellitus ◽

Fold Increase ◽

First Trimester ◽

Elevated Blood Pressure ◽

Elevated Blood ◽

Increased Risk ◽

First Trimester Of Pregnancy

Objective. To determine the relationship between blood pressure measured during the first trimester of pregnancy and the risk of the development of gestational diabetes mellitus. Design and methods. A total of 209 pregnant women were screened for gestational diabetes mellitus between weeks 24 and 28 of gestation, as defined by WHO criteria. Blood pressure, weight and waist circumference data were obtained by review of the medical records. Results. An elevated blood pressure at first trimester of pregnancy was associated with a six-fold increase in the risk of the development of gestational diabetes mellitus (OR = 5.8, 95 % CI 1.9-17.5, p = 0.001) compared with non-hypertensive women. Arterial hypertension (including controlled forms) in the first trimester of pregnancy was followed by a three-fold (OR = 3.04, 95 % CI 1.5-6.3) increase in the risk of gestational diabetes mellitus compared with non-hypertensive women (p = 0.005). Conclusion. Obtained data indicate that women with elevated blood pressure in the first trimester of pregnancy have an increased risk of the development of gestational diabetes mellitus.

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