scholarly journals Ethnographic Study of Perspective and Attitude of Breastfeeding Mothers Towards the use of Elaeis Guineensis Sap As Galactagogue Among Igbo Women Oof Southeastern Nigeria

2021 ◽  
pp. 1-7
Author(s):  
Okamkpa Jude Chikezie ◽  
Anibeze Ikechukwu Chike ◽  
Ozor Ikemefuna Ignatius ◽  
Ikenna Kingsely Ndu ◽  
Uchenna Anthony Umeh
Keyword(s):  
Side Effects ◽  
Elaeis Guineensis ◽  
Tertiary Education ◽  
Ethnographic Study ◽  
Palm Tree ◽  
Efficacy And Safety ◽  
Traditional Practice ◽  
Southeastern Nigeria ◽  
Palm Wine ◽  
Chi Square Analysis

OBJECTIVE: As an age-old traditional practice, nursing mothers from southeastern Nigeria use the Elaeis guineensis sap (from the oil palm tree also referred to as palm wine) to induce and sustain lactation a few hours after delivery. This practice is still ongoing to date, despite the scarcity of clinical data supporting its efficacy and safety. This study aimed to generate preliminary data on the prevalence, perceptions, and behaviors related to the use of Elaeis guineensis sap as a galactagogue. STUDY DESIGN: Mothers who had breastfed or breastfeeding at the time of the survey, were invited to complete a questionnaire that asked about their, perceptions, efficacy, and possible side effects of Elaeis guineensis sap on both mother and child during breastfeeding. Chi-square analysis was used to conduct data analysis. RESULT: A total of 5002 mothers completed the survey with 61% reporting use of Elaeis guineensis sap (palm wine) following parturition. Most of the respondents (73%) attained tertiary education. The practice was mostly recommended by direct relatives (38%) while the commonest reason for this practice was perceived insufficient milk production (32.2%). The majority of the respondents (52%) were satisfied with the outcome while 44% reported no negative side effects. CONCLUSION: The use of Elaeis guineensis sap by mothers following parturition is common in south-eastern Nigeria. However, randomized control studies are needed to provide evidence for the efficacy and safety of this plant product. This will be relevant to the formation of intercultural health policies which will value and respect the positive cultural practices of a people.

scholarly journals Chemical Composition of Some Natural Palm Wine Preservatives

2017 ◽  
Vol 8 (3) ◽  
pp. 73
Author(s):  
Ngounou Batchanji Steve ◽  
Feumba Dibanda Romelle ◽  
Yadang Germaine ◽  
Nyobe Emillienne Carine ◽  
Achegui Nestor ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Elaeis Guineensis ◽  
Central Africa ◽  
Threshold Value ◽  
Palm Tree ◽  
Adansonia Digitata ◽  
Palm Wine ◽  
Sugar Fermentation ◽  
Total Alkaloids ◽  
West And Central Africa

Palm wine is the commonest name of the beverage obtained from fermented palm sap, the exudate from tapped unopened spathe of oil palm tree (Elaeis guineensis). This refreshing wine of West and Central Africa is very sweet but within 24 hours the concentration of sucrose falls to less than 50% the initial amounts due to a rapid sugar fermentation by microorganisms. In Cameroon, Central Africa, traditional attempts to preserve palm wine imply the introduction of natural preservatives mostly barks and leaves from edible or medicinal plants. The leaves of Cymbopogon citratus, Pimenta racemosa, Vernonia amygdalina, Ocimum basilicum and the barks and the leaves of Garcinia lucida and of Adansonia digitata commonly used in palm wine preservation were analyzed for their chemical composition. The results showed that lipid, protein, ash, crude fiber, total sugars and vitamin C contents were respectively from 15.70 ± 1.13 to 23.57 ± 1.80%, from 8.38 ± 0.38 to 43.81 ± 3.69%, from 1.14 ± 0.17 to 10.06 ± 0.39%, from 11.74 ± 1.11 to 48.42 ± 0.55%, and from 1.49 ± 0.02 to 22.56 ± 0.59% and from 55.76 ± 3.15 to 175.71 ± 2.09 μg /100 g dw. The phyto-chemicals levels were respectively from 1.37 ± 0.22 to 3.61 ± 0.6 % for total alkaloids, 2.66 ± 0.12 to 4.80 ± 0.24 % for total phenolics and 0.57 ± 0.09 to 1.88 ± 0.09 mg /100 g dw for total saponins. Concerning anti-nutrients, the oxalates levels were higher than the threshold value (250 mg/100 g) reported as safety limit. Despise the proven antimicrobial benefits of alkaloids, saponins and phenolics found in those leaves and barks, caution shall be paid during their use due to their high oxalates levels.

scholarly journals Ethnobotany of Elaeis guineensis Jacq. and its importance in the household economy of the Ikale and Ilaje of Ondo State, Nigeria

2020 ◽  
Vol 20 ◽  
Author(s):  
Sakiru Morenikeji Erinoso ◽  
David Olaniran Aworinde ◽  
Olasimbo Anuoluwapo Teniola ◽  
Samuel Omoniyi Ojo
Keyword(s):  
Palm Oil ◽  
Oil Palm ◽  
Elaeis Guineensis ◽  
Palm Kernel ◽  
Palm Tree ◽  
Perennial Crop ◽  
Palm Wine ◽  
Ondo State ◽  
Elaeis Guineensis Jacq ◽  
African Oil Palm

Background: African oil palm (Elaeis guineensis Jacq.), a perennial crop that originated from Tropical rainforest of West Africa, is one of the most important economic oil crops in Nigeria providing income for rural and semi-urban folks. This study described the ethnobotany of the plant and evaluated the extent to which it contributes to the livelihood strategies of the Ikale and Ilaje speaking people of Ondo State, Nigeria. Methods: Interviews were conducted in the local language and questionnaires were administered to willing respondents. Photographs of tools/machines used in the production of palm oil and allied products were taken. Drawings of the tools were generated on site. Results: The plant is the principal source of palm oil. Major processing tools of palm oil include cracker, presser, digester, and boiling trough. Other products that are derived from oil palm parts are palm kernel oil, kernel meat (for livestock feed), kernel shells (for fuel), palm wine, broom, fish trap, and traditional soap. All these products are made using indigenous methods. They feature in medicinal preparations, traditional ceremonies and are important household commodities. Conclusions: The products derived from oil palm tree serve as means of livelihood in the study communities and are local resources used in everyday activities of the people. The indigenous production methods observed further emphasize the role these products play in the economy of oil palm product makers and sellers. Sustainable tapping of palm wine should be encouraged in order to derive maximum benefits from oil palm tree. Keywords: Ethnobotany, Economic Botany, African Oil Palm, Ondo State, Nigeria

scholarly journals Effects of Lactobacillus spp. isolated from the sap of palm tree Elaeis guineensis (palm wine) on cellular and innate immunity

2019 ◽  
Vol 13 (2) ◽  
pp. 33-39 ◽  
Author(s):  
Christopher Osita Eze ◽  
Dinebari Philip Berebon ◽  
Thadeus Harrison Gugu ◽  
Chukwuemeka Sylvester Nworu ◽  
Charles Okechukwu Esimone
Keyword(s):  
Innate Immunity ◽  
Elaeis Guineensis ◽  
Palm Tree ◽  
Palm Wine ◽  
Lactobacillus Spp

EFFICACY OF CARVEDILOL COMBINED WITH ENDOSCOPIC VARICEAL LIGATION IN THE PREVENTION OF RECURRENT VARICEAL BLEEDING IN PATIENTS OF CIRRHOSIS

2016 ◽  
pp. 23-30
Author(s):  
Van Huy Tran ◽  
Thi Ngoc Diep Bui
Keyword(s):  
Side Effects ◽  
Beta Blocker ◽  
Variceal Bleeding ◽  
Poor Prognosis ◽  
Oesophageal Varices ◽  
Endoscopic Variceal Ligation ◽  
Efficacy And Safety ◽  
Orthostatic Hypertension ◽  
Key Words Carvedilol ◽  
Very High

Background: The recurrent variceal bleeding is still very high with a very poor prognosis. The combination of a non-selective beta-blocker and endoscopic variceal ligation (EVL) is still a standard therapy for the prevention, but many patients showed no response to propranolol. Carvedilol is a new, non-selective beta-blocker having intrinsic alpha-blocker activity, but the data about the efficacy and safety of carvedilol is still very limited. This study is aimed at assessing the efficacy and safety of carvedilol combined with EVL in the prevention of recurrent variceal bleeding. Patients and methods: 33 patients having variceal bleeding were enrolled. All patients received carvedilol and were performed the EVL until variceal eradication. All the patients were followed after 9 months. Results: rate of variceal eradication of oesophageal varices was 87.88%; the recurrence rate of variceal bleeding was 12.12% after 9 months. The side effects of carvedilol were rare and not severe, including vertiges, headache, and orthostatic hypertension. Conclusion: Carvedilol combined with EVL appeared as a relatively safe and effective in the prevention of recurrent variceal bleeding in patients of cirrhosis. Key words: carvedilol, variceal bleeding, EVL

Tocilizumab in Giant Cell Arteritis: A Multicenter Retrospective Study of 34 Patients

2016 ◽  
Vol 43 (8) ◽  
pp. 1547-1552 ◽  
Author(s):  
Alexis Régent ◽  
Serge Redeker ◽  
Alban Deroux ◽  
Pierre Kieffer ◽  
Kim Heang Ly ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Side Effects ◽  
Adverse Events ◽  
Giant Cell Arteritis ◽  
Giant Cell ◽  
Multicenter Study ◽  
Efficacy And Safety ◽  
Severe Adverse Events ◽  
Retrospective Multicenter Study

Objective.To report the efficacy and safety of tocilizumab (TCZ) for giant cell arteritis (GCA).Methods.A retrospective multicenter study that included 34 patients receiving TCZ for GCA.Results.TCZ was effective in all but 6 patients, who still had mild symptoms. Mean glucocorticoid dose was tapered. One patient died and 3 patients had to stop TCZ therapy because of severe adverse events. Twenty-three patients stopped treatment; 8 of these experienced relapses after a mean of 3.5 ± 1.3 months.Conclusion.TCZ is effective in GCA. However, side effects occur. Whether this treatment has only a suspensive effect remains to be determined.

scholarly journals The Safety and Efficacy of Pregabalin Add-on Therapy in Restless Legs Syndrome Patients

2021 ◽  
Vol 12 ◽  
Author(s):  
Hyoeun Bae ◽  
Yong Won Cho ◽  
Keun Tae Kim ◽  
Richard P. Allen ◽  
Christopher J. Earley
Keyword(s):  
Side Effects ◽  
Restless Legs Syndrome ◽  
Severity Index ◽  
Efficacy And Safety ◽  
Restless Legs ◽  
Persistent Symptoms ◽  
Before And After ◽  
Severity Index Score ◽  
Irls Score ◽  
Symptomatic Control

Pregabalin is increasingly being used as a first-line treatment for symptomatic control of restless legs syndrome (RLS). This study aimed to evaluate the efficacy and safety of pregabalin as add-on therapy in RLS patients already taking dopamine agonists (DA) but still in need of further management. Patients with idiopathic RLS were enrolled, and all had already been prescribed DA for at least 3 months but still had either persistent symptoms, side effects, or comorbid insomnia. An initial dose of 75 mg pregabalin was begun, adjusted as needed, and maintained at a stable dose for 4 weeks, followed by observation for a total of 8 weeks. RLS symptoms and insomnia scores were evaluated before and after add-on pregabalin treatment. Patients were monitored for side effects that could be attributed to pregabalin. A total of 32 RLS patients were enrolled, and 20 subjects remained until the endpoint. After the pregabalin add-on, the mean IRLS score showed significant improvement compared to the baseline (p < 0.001). The insomnia severity index score also improved (p = 0.036), and no serious adverse effects were observed. Our preliminary data suggests the potential for pregabalin as an add-on therapy to DA with regards to both efficacy and safety in patients who have inadequate RLS improvement.

scholarly journals Biosorption Isotherms and Kinetics Studies for the Removal of 2,6-Dichlorophenolindophenol Using Palm Tree Trunk (<em>Elaeis guineensis</em>)

2018 ◽  
Vol 08 (03) ◽  
pp. 156-177 ◽  
Author(s):  
Marcel Cédric Deussi Ngaha ◽  
Lydiane Ghislaine Djemmoe ◽  
Evangéline Njanja ◽  
Ignas Tonle Kenfack
Keyword(s):  
Elaeis Guineensis ◽  
Palm Tree ◽  
Tree Trunk ◽  
Kinetics Studies

scholarly journals Efficacy and Safety of Carbon Dioxide Ablative Fractional Resurfacing (CO2-AFR) Device in Moderate to Severe Atrophic Acne Scars

2017 ◽  
Vol 23 (1) ◽  
Author(s):  
Wajieha Saeed ◽  
Zahida Rani ◽  
Shazia Aslam
Keyword(s):  
Side Effects ◽  
Objective Assessment ◽  
Side Effect Profile ◽  
Efficacy And Safety ◽  
Social Psychological ◽  
Interventional Study ◽  
Dermatology Department ◽  
Acne Scars ◽  
Fractional Resurfacing ◽  
Pretreatment Assessment

<p>Acne having a prevalence of &gt; 90% in adolescents persisting in adulthood, causes inflammation and scaring. Acne scars cause severe social, psychological and cosmetic problems. There are many remedies available for acne scars with variable results. CO2-AFR laser is a new modality with more effectiveness and low side effect profile.</p><p><strong>Objective:</strong><strong>  </strong>To determine the effectiveness and safety of CO2-AFR device in the treatment of moderate to severe atrophic acne scars.</p><p><strong>Study Design:</strong><strong>  </strong>Interventional study.</p><p><strong>Place and Duration of Study:</strong><strong>  </strong>This study was conducted at Dermatology Department Unit-I, Mayo Hospital Lahore and duration was 1 year, from April 2015 to March 2016.</p><p><strong>Material and Methods:</strong><strong>  </strong>The 30 patients of either sex, having moderate to severe atrophic acne scars were enrolled in the study. Pretreatment assessment of acne scars was done by using Goodman &amp; Baron qualitative scarring grading system. Patients were treated at 4 – 5 weeks interval with maximum 5 sessions. Objective assessment for efficacy and side effects was done at each session. Data was collected on a specially designed proforma and statistical analysis carried out by using SPSS version 17.</p><p><strong>Results:</strong><strong>  </strong>Significant improvement in acne scars was observed. 14 (46.7%) patients showed good efficacy (50 – 75% reduction), 1 (3.3%) patient came out with excellent efficacy (&gt; 75%) and 14 (46.7%) patients showed fair efficacy (25 – 50% reduction in acne scars). 13.3% patients showed few delayed side effects which resolved with treatment.</p><p><strong>Conclusion:</strong><strong>  </strong>CO2-AFR device was proved to be effective and safe in the treatment of moderate to severe atrophic acne scars.</p>

scholarly journals Therapeutic Index (TIX) for intranasal corticosteroids in the treatment of allergic rhinitis

2011 ◽  
Vol 49 (3) ◽  
pp. 272-280
Author(s):  
T. Schafer ◽  
M. Schnoor ◽  
M. Wagenmann ◽  
L. Klimek ◽  
C. Bachert
Keyword(s):  
Allergic Rhinitis ◽  
Side Effects ◽  
Clinical Decision Making ◽  
Therapeutic Index ◽  
Clinical Decision ◽  
Efficacy And Safety ◽  
Medline Search ◽  
Intranasal Corticosteroids ◽  
Ocular Symptoms ◽  
Safety Outcomes

Background: Intranasal corticosteroids (INS) are the first line treatment for allergic rhinitis (AR). To guide clinical decision-making, we created a therapeutic index (TIX) for INS reflecting efficacy and safety. Methods: A Medline search (1966 to June 2009) was carried out to identify all placebo-controlled randomized trials, and observational reports for safety issues, with Dexamethasone, Budesonide (BUD), Fluticasone propionate (FP), Fluticasone furoate (FF), Flunisolide, Mometasone furoate (MF), Triamcinolone (TRIAM), and Beclomethasone dipropionate (BDP) as treatment for AR. Data on three efficacy (nasal symptoms, ocular symptoms, global assessment) and three safety outcomes (epistaxis, growth, systemic ocular effects) were extracted. Meta analyses were performed for each INS and outcome and results were categorised into scores by quartiles. Scores of the three efficacy and safety outcomes were summed up to create summation scores for efficacy (ES) and side effects (AES), respectively with a maximum of 9 points. The TIX was then defined as the ratio of ES and AES. Results: Data of 84 studies were extracted. Based on availability of data, a TIX was calculated for 6 substances. BUD showed the highest efficacy score followed by MF and TRIAM. The lowest scores for side effects were achieved by MF and TRIAM followed by FP. These findings resulted in TIX scores of 7 and 5 for MF and TRIAM, respectively, indicating a high efficacy and low potential of adverse events. Medium scores were reached by BUD and FP and lower scores by BDP and FF. Conclusion: Although safety and efficacy is proven for all available INS by multiple studies, the systematic aggregation and analysis of data allows for a differentiated summary on clinically important features.

scholarly journals The efficacy and safety of quadruple therapy without bismuth (concomitant therapy) in the treatment of patients with Helicobacter pylori - associated gastric and duodenal peptic ulcer disease

2019 ◽  
Vol 91 (8) ◽  
pp. 28-33 ◽  
Author(s):  
A M Veliev ◽  
I V Maev ◽  
D N Andreev ◽  
D T Dicheva ◽  
A V Zaborovskii ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Helicobacter Pylori ◽  
Side Effects ◽  
Triple Therapy ◽  
Eradication Therapy ◽  
Test System ◽  
Efficacy And Safety ◽  
Concomitant Therapy ◽  
Quadruple Therapy ◽  
H Pylori

Aim. Evaluation of the efficacy and safety of quadrupletherapy without bismuth (concomitant therapy) in patients with Helicobacter pylori - associated gastric ulcer and duodenal ulcer in the framework of a comparative research in the population of patients in Russia. Materials and methods. A prospective randomized trial was conducted, which included 210 patients with H. pylori - associated gastric/duodenal ulcer without complications. During the process of randomization, the patients were divided into three equal groups (n=70) depending on the prescribed 10-day scheme of eradication therapy (ET): the first group received the classic triple scheme (Omeprazole 20 mg 2 times a day, Amoxicillin 1000 mg 2 times a day and Clarithromycin 500 mg 2 times a day); the second group received quadruple therapy with bismuth drugs (Omeprazole 20 mg 2 times a day, Tetracycline 500 mg 4 times a day, Metronidazole 500 mg 3 times a day, Bismuth subcitrate potassium 120 mg 4 times a day); the third group received quadruple therapy without bismuth - concomitant therapy (Omeprazole 20 mg 2 times a day, Amoxicillin 1000 mg 2 times a day, Clarithromycin 500 mg 2 times a day and Metronidazole 500 mg 2 times a day). Diagnostics of H. pylori infection during screening and control of eradication was carried out via the fast urease biopsy sample test and urea breath test system. Control of the effectiveness of ET of the microorganism was carried out not earlier than 4 weeks after the end of the treatment. During the course of therapy, the frequency of development of side effects was assessed using a special questionnaire. Results and discussion. The effectiveness of triple therapy was 72.8% (ITT; 95% CI of 62.17-83.54) and 78,4% (PP; 95% CI 68.19-88.72); quadruple therapy with the preparation of bismuth - 80.0% (ITT; 95% CI 70.39-89.6) and 84,8% (PP; 95% CI, 75.96-93.73); quadruple therapy without bismuth - concomitant therapy - 84.2% (ITT; 95% CI 75.54-93.02) and 92.1% (PP; 95% CI 85.43-98.94). Quadruple therapy without bismuth was reliably more effective than the classical triple therapy in the PP selection (p=0.044883). Statistical analysis showed a tendency to poorer effectiveness of ET in patients who had previously used antibiotic therapy (OR 0.4317; 95% CI 0.1776-1.049), and in individuals with a rapid metabolism genotype - CYP2C19*1/*1 (OR 0.12; 95% CI 0.005848-2.4624). The frequency of development of side effects during the use of triple therapy was 18.5% (95% CI of 9.23-27.91), when using quadruple therapy with bismuth - 20.0% (95% CI 10.39-29.6), and with the use of quadruple therapy without bismuth - concomitant therapy - 24.2% (95% CI 13.98-34.58). Conclusion. This prospective randomized study demonstrated the high efficiency of quadruple therapy without bismuth (concomitant therapy) in the framework of eradication of H. pylori infection in Russia.

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