scholarly journals Bone Density of the Femur and Fiber Cross-Sectional Area and Oxidative Enzyme Activity of the Tibialis Anterior Muscle in Type II Collagen-Induced Arthritic Mice

2008 ◽  
Vol 58 (4) ◽  
pp. 221-227 ◽  
Author(s):  
Tomonori Okiura ◽  
Fumiko Nagatomo ◽  
Ning Gu ◽  
Yasuki Taguchi ◽  
Fumiki Morimatsu ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Bone Density ◽  
Tibialis Anterior ◽  
Tibialis Anterior Muscle ◽  
Type Ii Collagen ◽  
Oxidative Enzyme ◽  
Type Ii ◽  
Sectional Area ◽  
Cross Sectional ◽  
Oxidative Enzyme Activity

scholarly journals Cell Size and Oxidative Enzyme Activity of Different Types of Fibers in Different Regions of the Rat Plantaris and Tibialis Anterior Muscles.

2000 ◽  
Vol 50 (4) ◽  
pp. 413-418 ◽  
Author(s):  
Toshiaki Nakatani ◽  
Toshikatsu Nakashima ◽  
Taizo Kita ◽  
Chiyoko Hirofuji ◽  
Kazuo Itoh ◽  
...  
Keyword(s):  
Enzyme Activity ◽  
Cell Size ◽  
Tibialis Anterior ◽  
Oxidative Enzyme ◽  
Oxidative Enzyme Activity ◽  
Different Types

scholarly journals Leg muscle cross-sectional area measured by ultrasound is highly correlated with MRI

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Joshua K. Sponbeck ◽  
Clint R. Frandsen ◽  
Sarah T. Ridge ◽  
Derek A. Swanson ◽  
Dallin C. Swanson ◽  
...  
Keyword(s):  
Tibialis Anterior ◽  
Tibialis Anterior Muscle ◽  
Cross Sectional Area ◽  
Tibialis Posterior ◽  
Sectional Area ◽  
Cross Sectional ◽  
Leg Muscles ◽  
Detectable Difference ◽  
Minimum Detectable Difference ◽  
Leg Muscle

Abstract Background The leg muscles are important for balance, posture, and movement during static and dynamic activity. Obtaining cross-sectional area measurements (CSA) of the leg muscles helps researchers understand the health and force production capability of individual leg muscles. Therefore, having an easy to use and readily available method to assess leg muscle CSA is needed. Thus, the purpose of this study was to compare the magnitude, repeatability, and validity of CSA measurements of select leg muscles from ultrasound (US) and the current gold standard, magnetic resonance imaging (MRI). Methods 20 healthy volunteers participated in this study. Each participant was imaged via US and MRI. The muscles of interest obtained on each participant consisted of the tibialis anterior at both 30 and 50% of the shank length, tibialis posterior at both 30 and 50% of the shank length, the flexor digitorum longus, the fibularis (peroneus) longus, and the fibularis (peroneus) brevis. Results Strong Pearson correlations were seen for all of the muscles when comparing US to MRI with a range from .7840 to .9676. For all measurements, standard error of the measurement ranged from .003 to 0.260 cm2. Minimum detectable difference for muscle measurements ranged from .008 cm2 for MRI fibularis longus and fibularis brevis to .693 cm2 for MRI of tibialis anterior at 30%. US minimum detectable difference ranged from .125 cm2 for the tibialis posterior muscle at 30% to .449 cm2 for the tibialis anterior muscle at 50%. Conclusions Based on these results ultrasound is a valid method to obtain CSA of muscles of the leg when compared with MRI.

scholarly journals Chronic progressive external ophthalmoplegia: I. A quantitative histochemical study of skeletal muscles

1988 ◽  
Vol 46 (2) ◽  
pp. 133-142 ◽  
Author(s):  
Elza Dias-Tosta
Keyword(s):  
Enzyme Activity ◽  
Muscle Weakness ◽  
Positive Family History ◽  
Oxidative Enzyme ◽  
Progressive External Ophthalmoplegia ◽  
Muscle Fibres ◽  
Chronic Progressive External Ophthalmoplegia ◽  
Limb Muscle ◽  
Oxidative Enzyme Activity ◽  
Group 2

This study quantitates the major morphological and cytochemical changes in limb muscle biopsies from 37 patients with the, syndrome of chronic progressive external ophthalmoplegia (CPEO). The aim was to assess the value of limb muscle biopsy in the diagnosis of this syndrome; to define the myopathological changes and to determine whether there were any specific clinico-pathological correlations. Patients were divided into three clinical groups - 11 patients with CPEO with facial and/or limb muscle weakness; 10 with CPEO with facial and/or limb muscle weakness and a positive family history; 16 with CPEO with one or more of the following: pigmentary retinopathy, cerebellar ataxia, pyramidal signs and peripheral neuropathy. The following parameters were measured: the proportions of histochemical fibre types, the muscle fibre areas and the percentage of muscle fibres showing increased oxidative enzyme activity. Pooled results for each of the clinical categories were compared. Statistical analysis of fibre areas and the percentage of fibres with increased oxidative enzyme activity, showed that group 2 differed from the others (p < 0.05). Patients in group 2 showed the highest incidence of type 1 fibre hypertrophy, type 2A atrophy and the lowest incidence of fibres with increased oxidative activity. Fibre type disproportions occurred in all three groups but the differences were not significant.

Maximal force as a function of anatomical features of motor units in the cat tibialis anterior

1987 ◽  
Vol 57 (6) ◽  
pp. 1730-1745 ◽  
Author(s):  
S. C. Bodine ◽  
R. R. Roy ◽  
E. Eldred ◽  
V. R. Edgerton
Keyword(s):  
Motor Unit ◽  
Tibialis Anterior ◽  
Periodic Acid ◽  
Muscle Fibers ◽  
Motor Units ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Periodic Acid Schiff ◽  
Cross Sectional ◽  
Single Motor Unit

In 11 tibialis anterior muscles of the cat, a single motor unit was characterized physiologically and subsequently depleted of its glycogen through repetitive stimulation of an isolated ventral root filament. Muscle cross sections were stained for glycogen using a periodic acid-Schiff reaction, and single-fiber optical densities were determined to identify those fibers belonging to the stimulated motor unit. Innervation ratios were determined by counting the total number of muscle fibers in a motor unit in sections taken through several levels of the muscle. The average innervation ratios for the fast, fatigueable (FF) and fast, fatigue-resistant (FR) units were similar. However, the slow units (S) contained 61% fewer fibers than the fast units (FF and FR). Muscle fibers belonging to S and FR units were similar in cross-sectional area, whereas fibers belonging to FF units were significantly larger than fibers belonging to either S or FR units. Additionally, muscle fibers innervated by a single motoneuron varied by two- to eightfold in cross-sectional area. Specific tensions, based on total cross-sectional area determined by summing the areas of all muscle fibers of each unit, showed a modest difference between fast and slow units, the means being 23.5 and 17.2 N X cm-2, respectively. Variations in maximum tension among units could be explained principally by innervation ratio, although fiber cross-sectional area and specific tension did contribute to differences between unit types.

Interactive effects of emphysema and malnutrition on diaphragm structure and function

1994 ◽  
Vol 77 (2) ◽  
pp. 947-955 ◽  
Author(s):  
M. I. Lewis ◽  
S. A. Monn ◽  
W. Z. Zhan ◽  
G. C. Sieck
Keyword(s):  
Succinate Dehydrogenase ◽  
Dehydrogenase Activity ◽  
Cross Sectional Area ◽  
Interactive Effects ◽  
Type I ◽  
Specific Force ◽  
Type Ii ◽  
Sectional Area ◽  
Succinate Dehydrogenase Activity ◽  
Cross Sectional

Interactive effects of emphysema (EMP) and prolonged nutritional deprivation (ND) on contractile, morphometric, and metabolic properties of hamster diaphragm muscle (DIA) were examined. Six months after induction of EMP (intratracheal elastase), saline-treated controls (CTL) and EMP hamsters of similar body weights were subjected to ND over 6 wk. Isometric contractile and fatigue properties of costal DIA were determined in vitro. DIA fibers were histochemically classified as type I or II, and fiber succinate dehydrogenase activity and cross-sectional area were determined using quantitative microscopic procedures. From histochemical sections, the number of capillaries per fiber (C/F) and per fiber cross-sectional area (C/A) were determined. ND resulted in progressive loss of body weight (ND-CTL, 23.8%; ND-EMP, 28.4%; P = NS). ND did not affect reduction in optimal length (Lo) of DIA fibers in EMP compared with CTL and ND-CTL hamsters. Maximum specific force (i.e., force/unit area) was reduced by approximately 25% in EMP animals compared with CTL. ND did not improve or exacerbate the reduction in specific force with EMP. ND attenuated improved fatigue resistance of DIA in EMP animals. No differences in fiber type proportions were noted among experimental groups. Significant atrophy of type I and II DIA fibers was noted after ND. Atrophy was proportionately greater in type II fibers of ND-EMP when referenced to EMP animals. Thus adaptive hypertrophy of type II DIA fibers in EMP animals was abolished. Fiber succinate dehydrogenase activity was significantly increased in type I and II fibers in EMP DIA. ND did not affect this metabolic adaptation of DIA fibers to persistent loads imposed by EMP.(ABSTRACT TRUNCATED AT 250 WORDS)

Sign in / Sign up

Export Citation Format

Share Document