Regioselective Synthesis of Diverse Thio-, Seleno-substituted 1,2,3-Triazoles
Keyword(s):
: Thio-, seleno-substituted triazoles are useful scaffolds employed in the fields of organic synthesis, medicinal chemistry, and material science. A number of synthetic approaches to efficient formation of thio- and seleno-triazoles have been disclosed, including the interception of copper(I) triazolides generated in-situ, cycloaddition of internal alkynes (thio-, halo-, and metalated alkynes) to azides, and the coupling of azides and nonalkyne substrates. This mini-review intends to summarize the synthetic methods toward thio-, seleno-1,2,3-triazoles and the relative reaction mechanisms.
2019 ◽
Keyword(s):
2019 ◽
Vol 16
(3)
◽
pp. 342-368
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