Solid Matrix Based Lipidic Nanoparticles in Oral Cancer Chemotherapy: Applications and Pharmacokinetics

2015 ◽  
Vol 16 (8) ◽  
pp. 633-644 ◽  
Author(s):  
Javed Ahmad ◽  
Saima Amin ◽  
Mahfoozur Rahman ◽  
Rehan Rub ◽  
Madhur Singhal ◽  
...  
Drugs ◽  
1999 ◽  
Vol 58 (Supplement 3) ◽  
pp. 133-140 ◽  
Author(s):  
W Archie Bleyer ◽  
Martha G. Danielson

Author(s):  
Richard Oliver ◽  
Jan E Clarkson ◽  
David Conway ◽  
Anne-Marie Glenny ◽  
Michaelina Macluskey ◽  
...  

Drug Delivery ◽  
2019 ◽  
Vol 26 (1) ◽  
pp. 542-550 ◽  
Author(s):  
Weiping Cui ◽  
Hanqing Zhao ◽  
Chen Wang ◽  
Yao Chen ◽  
Cong Luo ◽  
...  

Author(s):  
Karvita B. Ahluwalia ◽  
Nidhi Sharma

It is common knowledge that apparently similar tumors often show different responses to therapy. This experience has generated the idea that histologically similar tumors could have biologically distinct behaviour. The development of effective therapy therefore, has the explicit challenge of understanding biological behaviour of a tumor. The question is which parameters in a tumor could relate to its biological behaviour ? It is now recognised that the development of malignancy requires an alteration in the program of terminal differentiation in addition to aberrant growth control. In this study therefore, ultrastructural markers that relate to defective terminal differentiation and possibly invasive potential of cells have been identified in human oral leukoplakias, erythroleukoplakias and squamous cell carcinomas of the tongue.


Author(s):  
S. Hagège ◽  
U. Dahmen ◽  
E. Johnson ◽  
A. Johansen ◽  
V.S. Tuboltsev

Small particles of a low-melting phase embedded in a solid matrix with a higher melting point offer the possibility of studying the mechanisms of melting and solidification directly by in-situ observation in a transmission electron microscope. Previous studies of Pb, Cd and other low-melting inclusions embedded in an Al matrix have shown well-defined orientation relationships, strongly faceted shapes, and an unusual size-dependent superheating before melting.[e.g. 1,2].In the present study we have examined the shapes and thermal behavior of eutectic Pb-Cd inclusions in Al. Pb and Cd form a simple eutectic system with each other, but both elements are insoluble in solid Al. Ternary alloys of Al (Pb,Cd) were prepared from high purity elements by melt spinning or by sequential ion implantation of the two alloying additions to achieve a total alloying addition of up to lat%. TEM observations were made using a heating stage in a 200kV electron microscope equipped with a video system for recording dynamic behavior.


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