Identifying Cancer Targets Based on Machine Learning Methods via Chou’s 5-steps Rule and General Pseudo Components

2019 ◽  
Vol 19 (25) ◽  
pp. 2301-2317 ◽  
Author(s):  
Ruirui Liang ◽  
Jiayang Xie ◽  
Chi Zhang ◽  
Mengying Zhang ◽  
Hai Huang ◽  
...  

In recent years, the successful implementation of human genome project has made people realize that genetic, environmental and lifestyle factors should be combined together to study cancer due to the complexity and various forms of the disease. The increasing availability and growth rate of ‘big data’ derived from various omics, opens a new window for study and therapy of cancer. In this paper, we will introduce the application of machine learning methods in handling cancer big data including the use of artificial neural networks, support vector machines, ensemble learning and naïve Bayes classifiers.

Author(s):  
Mojtaba Montazery ◽  
Nic Wilson

Support Vector Machines (SVM) are among the most well-known machine learning methods, with broad use in different scientific areas. However, one necessary pre-processing phase for SVM is normalization (scaling) of features, since SVM is not invariant to the scales of the features’ spaces, i.e., different ways of scaling may lead to different results. We define a more robust decision-making approach for binary classification, in which one sample strongly belongs to a class if it belongs to that class for all possible rescalings of features. We derive a way of characterising the approach for binary SVM that allows determining when an instance strongly belongs to a class and when the classification is invariant to rescaling. The characterisation leads to a computation method to determine whether one sample is strongly positive, strongly negative or neither. Our experimental results back up the intuition that being strongly positive suggests stronger confidence that an instance really is positive.


2020 ◽  
Vol 33 (2) ◽  
pp. e100197 ◽  
Author(s):  
Tsung-Chin Wu ◽  
Zhirou Zhou ◽  
Hongyue Wang ◽  
Bokai Wang ◽  
Tuo Lin ◽  
...  

Mental health questions can be tackled through machine learning (ML) techniques. Apart from the two ML methods we introduced in our previous paper, we discuss two more advanced ML approaches in this paper: support vector machines and artificial neural networks. To illustrate how these ML methods have been employed in mental health, recent research applications in psychiatry were reported.


Author(s):  
Akshay Rajendra Naik ◽  
A. V. Deorankar ◽  
P. B. Ambhore

Rainfall prediction is useful for all people for decision making in all fields, such as out door gamming, farming, traveling, and factory and for other activities. We studied various methods for rainfall prediction such as machine learning and neural networks. There is various machine learning algorithms are used in previous existing methods such as naïve byes, support vector machines, random forest, decision trees, and ensemble learning methods. We used deep neural network for rainfall prediction, and for optimization of deep neural network Adam optimizer is used for setting modal parameters, as a result our method gives better results as compare to other machine learning methods.


2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Jingyi Mu ◽  
Fang Wu ◽  
Aihua Zhang

In the era of big data, many urgent issues to tackle in all walks of life all can be solved via big data technique. Compared with the Internet, economy, industry, and aerospace fields, the application of big data in the area of architecture is relatively few. In this paper, on the basis of the actual data, the values of Boston suburb houses are forecast by several machine learning methods. According to the predictions, the government and developers can make decisions about whether developing the real estate on corresponding regions or not. In this paper, support vector machine (SVM), least squares support vector machine (LSSVM), and partial least squares (PLS) methods are used to forecast the home values. And these algorithms are compared according to the predicted results. Experiment shows that although the data set exists serious nonlinearity, the experiment result also show SVM and LSSVM methods are superior to PLS on dealing with the problem of nonlinearity. The global optimal solution can be found and best forecasting effect can be achieved by SVM because of solving a quadratic programming problem. In this paper, the different computation efficiencies of the algorithms are compared according to the computing times of relevant algorithms.


2019 ◽  
Vol 18 (2) ◽  
Author(s):  
Abdul Azis Abdillah

ABSTRACTSupport Vector Machines (SVM) are known as the latest machine learning (machine learning) methods to solve classification problems in pattern recognition. This paper discusses the use of SVM in solving problems in pattern recognition. An example of the problem given in this paper contains a collection of data on Any Linearly Separable Datase, Any dataset with Noise, and Real datasets.Key words: machine learning, pattern recognition, SVMABSTRAKSupport Vector Machines (SVM) dikenal sebagai metode machine learning (pembelajaran mesin) paling mutakhir untuk menyelesaikan masalah klasifikasi pada pengenalan pola. Tulisan ini bertujuan untuk membahas penggunaan SVM dalam memecahkan masalah klasifikasi pada pengenalan pola. Contoh masalah yang diberikan pada tulisan ini meliputi klasifikasi data pada Sembarang Linearly Separable Dataset, Sembarang Dataset dengan Noise, dan Real dataset.Kata kunci : klasifikasi, pengenalan pola, SVM


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