Construction Model of Cardiac Purkinje System

This research focuses on the emergency-housing demand caused by the on-going refugee crisis in Southeastern Europe. The research and proposed solutions focus on Northern Serbia, as this region generally lacks permanent housing solutions for accommodating the increasing influx of immigrants. The outcome of this research is an architectural proposal for the refugee housing unit designed particularly for the situational factors of this focus region. The study identifies earth architecture as the primary building technique, due to its ability to satisfy a range of defined end-product goals. These goals include: the sustainability of the material, quality and durability of the final product, skill level required for non-professional construction, final cost of material and execution, historical regional precedent, and opportunity for communal engagement of the immigrant population. The proposed architectural design uses earth-bag construction as the sub-method most suitable for this location and in keeping with the goals outlined above. The proposed housing unit is a singular component that could be duplicated to create larger communal housing communities. A broad overview of possible solutions is included, followed by the development of the earth-bag construction option. The development of this proposal includes material studies, sketches, and an architectural model as representation tools. The outcomes of this research serve as a guideline, rather than a precise construction model, in creating much needed refugee housing communities in North Serbia.

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Analysis and Simulation Methods of the Mechanisms for the Innovational Development

Экономическая наука современной России ◽

10.33293/1609-1442-2019-1(84)-16-33 ◽

2019 ◽

pp. 16-33

Author(s):

Marta K. Isaeva

Keyword(s):

Production Systems ◽

Technological Development ◽

Computer Experiment ◽

Simulation Models ◽

Construction Simulation ◽

Technological Structure ◽

Research Sector ◽

Practical Trial ◽

Construction Model ◽

Computation Analysis

The paper dedicates in commemoration of K.A. Bagrinovsky, known scientist, doctor of economic sciences, professor. His thesis was theoretic problems of mathematical modeling and operation of economy. His works in the operations research, the methods making decision, the simulation were received in scientific world. The analysis and the modeling of the mechanisms for scientific and technological development for the production systems of different level in economic hierarchic both centrally controlled economy and making mechanism were conduced by Bagrinovsky in CEMI RAS. The paper presents the investigations (2001–2015) of the analysis and the simulation of the different mechanisms of the innovational activity. It also discusses the methods of the development the complex of the simulation models. In a sense simulation modeling is the science and the art as the selection of the salient parameters for the construction model, intake simplification, the computer experiment and the making decision based on scarcity of accuracy models rest on the heuristic power of men: the practical trial, the intelligence and the intuition. K.A. Bagrinovsky introduced the considerable endowment in the development of this direction for economic and mathematical investigation.The principal object was to show that the relationship between the innovational policy and the technological structure, scientific research sector and the introducing of the progressive production and the organizational structure is obtainable by the models. The character of these relationships may be to use in control of the parameters for the modernization economic. The construction simulation models and the experimental computation analysis were presented the investigations the different mechanisms of the innovational development ant the variants of the estimation have been accomplished on the modeling level by the computer experiment.

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Expert’s Opinion–Challenging ECG

Indian Journal of Cardiovascular Disease in Women WINCARS ◽

10.1055/s-0040-1722766 ◽

2020 ◽

Vol 5 (04) ◽

pp. 368-372

Author(s):

Seema Kale

Keyword(s):

Myocardial Ischaemia ◽

Heart Block ◽

Complete Heart Block ◽

Conduction System ◽

Av Block ◽

Av Node ◽

Purkinje System ◽

Expert’S Opinion

AbstractVarying kinds of AV blocks can occur in the setting of myocardial ischaemia or due to degeneration of conduction system. Wenckebach AV block can present with typical Wenckebach periodicity or atypical periodicity. A variant of atypical Wenckebach periodicity may present like Mobitz II AV block. This is called Pseudo Mobitz II AV block. As we are aware that Mobitz II AV block is more dangerous and can suddenly convert into complete heart block, it is essential that we should try to differentiate between Mobitz and Pseudo Mobitz II blocks. Infact atypical Wenckebach cycles are quite common at both AV node and his Purkinje system.

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Empirical Ablation to Prevent Sequential Purkinje System Recruitment

JACC: Case Reports ◽

10.1016/j.jaccas.2021.01.018 ◽

2021 ◽

Vol 3 (3) ◽

pp. 517-522

Author(s):

Pattara Rattanawong ◽

Vatsal Ladia ◽

Nareg Minaskeian ◽

Dan Sorajja ◽

Win-Kuang Shen ◽

...

Keyword(s):

Purkinje System

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Research on Intelligent Transportation Construction Model Based on Computer Technology

Journal of Physics Conference Series ◽

10.1088/1742-6596/1915/2/022008 ◽

2021 ◽

Vol 1915 (2) ◽

pp. 022008

Author(s):

Chen Chen ◽

Yandang Jia

Keyword(s):

Computer Technology ◽

Intelligent Transportation ◽

Model Based ◽

Transportation Construction ◽

Construction Model

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Examining the Career Construction Model of Adaptation Among Filipino Senior High School Students

Journal of Career Development ◽

10.1177/08948453211037011 ◽

2021 ◽

pp. 089484532110370

Author(s):

Marc Sherwin A. Ochoco ◽

Welison Evenston G. Ty

Keyword(s):

High School ◽

Life Satisfaction ◽

High School Students ◽

Well Being ◽

Senior High School ◽

Career Adaptability ◽

School Students ◽

Career Construction ◽

Construction Model ◽

Senior High School Students

Career development literature that tested the career construction model of adaptation has, thus far, examined adaptability resource as a mediator in the relationship between adaptive readiness and adaptation results; however, there remains a need to elaborate the links between adaptive resources, adapting response, and adaptation results. This research tested a path model among 331 Filipino senior high school students using hope, career adaptability, career engagement, and life satisfaction as measures of adaptive readiness, adaptability resources, adaptive response, and adaptation results, respectively. Analyses revealed a significant serial relationship from hope to life satisfaction through career adaptability and career engagement. Findings suggest that having career-related abilities may not be enough to promote well-being; rather proactive career behaviors may be taken as a route to a satisfying life. Implications on theory, research, and practice are discussed.

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Automated Framework for the Inclusion of a His–Purkinje System in Cardiac Digital Twins of Ventricular Electrophysiology

Annals of Biomedical Engineering ◽

10.1007/s10439-021-02825-9 ◽

2021 ◽

Author(s):

Karli Gillette ◽

Matthias A. F. Gsell ◽

Julien Bouyssier ◽

Anton J. Prassl ◽

Aurel Neic ◽

...

Keyword(s):

Cardiac Electrophysiology ◽

Ventricular Myocardium ◽

Activation Patterns ◽

Purkinje System ◽

Digital Twins ◽

Emergent Features ◽

Ventricular Activation ◽

Endocardial Layer ◽

Right Ventricular Apical Pacing ◽

Electrocardiogram Ecg

AbstractPersonalized models of cardiac electrophysiology (EP) that match clinical observation with high fidelity, referred to as cardiac digital twins (CDTs), show promise as a tool for tailoring cardiac precision therapies. Building CDTs of cardiac EP relies on the ability of models to replicate the ventricular activation sequence under a broad range of conditions. Of pivotal importance is the His–Purkinje system (HPS) within the ventricles. Workflows for the generation and incorporation of HPS models are needed for use in cardiac digital twinning pipelines that aim to minimize the misfit between model predictions and clinical data such as the 12 lead electrocardiogram (ECG). We thus develop an automated two stage approach for HPS personalization. A fascicular-based model is first introduced that modulates the endocardial Purkinje network. Only emergent features of sites of earliest activation within the ventricular myocardium and a fast-conducting sub-endocardial layer are accounted for. It is then replaced by a topologically realistic Purkinje-based representation of the HPS. Feasibility of the approach is demonstrated. Equivalence between both HPS model representations is investigated by comparing activation patterns and 12 lead ECGs under both sinus rhythm and right-ventricular apical pacing. Predominant ECG morphology is preserved by both HPS models under sinus conditions, but elucidates differences during pacing.

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