Multicomponent Reactions in the Synthesis of Complex Fused Coumarin Derivatives

2018 ◽  
Vol 15 (1) ◽  
pp. 21-37 ◽  
Author(s):  
Ligia S. da Silveira Pinto ◽  
Mara R.C. Couri ◽  
Marcus V.N. de Souza
Keyword(s):  
Natural Products ◽  
Green Chemistry ◽  
Multicomponent Reactions ◽  
High Selectivity ◽  
Complex Compounds ◽  
Important Class ◽  
Coumarin Derivatives ◽  
One Pot

Background: Coumarin is an important class of natural products with applications in different areas of knowledge. Due to its importance, several methodologies and strategies have been developed for the synthesis of different classes of compounds containing this nucleus. Objective: The aim of this review is to cover in the last five years the complex fused coumarin derivatives synthesized in one-pot three-component reactions. Conclusion: Considering that multicomponent reactions are a powerful tool to produce simple and complex compounds in one or few steps with high selectivity and yields while following the green chemistry principles.

scholarly journals Step economy in the Stereoselective Synthesis of Functionalized Oxindoles via Organocatalytic Domino/One-pot Reactions

2021 ◽  
Vol 25 ◽  
Author(s):  
Martina Bortolami ◽  
Francesca Leonelli ◽  
Marta Feroci ◽  
Fabrizio Vetica
Keyword(s):  
Natural Products ◽  
Asymmetric Synthesis ◽  
Bioactive Compounds ◽  
Stereoselective Synthesis ◽  
Environmentally Friendly ◽  
Important Class ◽  
One Pot ◽  
Asymmetric Organocatalysis ◽  
Toxic Approach

: Oxindoles are an important class of heterocyclic scaffolds widely present in natural products and bioactive compounds. For this reason, a plethora of methodologies for the stereoselective synthesis of enantioenriched oxindoles has been studied over the years. Among all the reported synthetic strategies, organocatalysis has proven to be a powerful tool for the asymmetric synthesis of this class of compounds being a step- and atom-economical, environmentally friendly, and non-toxic approach. This review will outline the application of asymmetric organocatalysis in the synthesis of chiral oxindole-based structures, relying on domino/one-pot reaction sequences in a step-economical fashion.

Facile and Efficient Synthesis of New Class of Imidazole Derivatives via One-Pot Multicomponent Reactions in Water

2013 ◽  
Vol 16 (10) ◽  
pp. 788-790
Author(s):  
Zinatossadat Hossaini ◽  
Samereh Seyfi ◽  
Faramarz Rostami-Charati ◽  
Mehdi Ghambarian
Keyword(s):  
Multicomponent Reactions ◽  
Efficient Synthesis ◽  
One Pot ◽  
Imidazole Derivatives ◽  
New Class

A Facile, One-Pot Synthesis of Azoic Compounds and Anthraquinone Derivatives Containing Dialkyl Phosphoryl Moieties in Multicomponent Reactions

2010 ◽  
Vol 185 (7) ◽  
pp. 1395-1403 ◽  
Author(s):  
Ghasem Marandi ◽  
Malek Taher Maghsoodlou ◽  
Reza Heydari ◽  
Sayyed Mostafa Habibi-Khorassani ◽  
Roya Kabiri ◽  
...  
Keyword(s):  
Multicomponent Reactions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Anthraquinone Derivatives

One-pot multicomponent synthesis of highly functionalized bio-active pyrano[2,3-c]pyrazole and benzylpyrazolyl coumarin derivatives using ZrO2 nanoparticles as a reusable catalyst

2015 ◽  
Vol 17 (5) ◽  
pp. 2859-2866 ◽  
Author(s):  
Arijit Saha ◽  
Soumen Payra ◽  
Subhash Banerjee
Keyword(s):  
Room Temperature ◽  
Zro2 Nanoparticles ◽  
Reusable Catalyst ◽  
Coumarin Derivatives ◽  
Multicomponent Synthesis ◽  
One Pot

Herein, a facile one-pot multicomponent protocol for the synthesis of biologically important pyrano[2,3-c]pyrazole and benzylpyrazolyl coumarin derivatives has been demonstrated using ZrO2 nanoparticles as reusable catalyst at room temperature.

scholarly journals Barium Dichloride as a Powerful and Inexpensive Catalyst for the Pechmann Condensation without Using Solvent

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Saeed Khodabakhshi
Keyword(s):  
Green Chemistry ◽  
Organic Solvents ◽  
Condensation Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Coumarin Derivatives ◽  
Inexpensive Method ◽  
Keto Esters ◽  
Pechmann Condensation ◽  
Solvent Free Conditions

Various coumarin derivatives have been efficiently synthesized via barium dichloride-catalyzed Pechmann condensation reaction of various phenols and β-keto esters under solvent-free conditions. This novel and inexpensive method has advantages such as short reaction times, excellent product yields, and avoidance of organic solvents in agreement with green chemistry principles.

Sign in / Sign up

Export Citation Format

Share Document