A Systematic Review of Double Low-dose CT Pulmonary Angiography in Pulmonary Embolism

2019 ◽  
Vol 15 (5) ◽  
pp. 453-460 ◽  
Author(s):  
Sultan Aldosari ◽  
Zhonghua Sun
Keyword(s):  
Systematic Review ◽  
Pulmonary Embolism ◽  
Image Quality ◽  
Radiation Dose ◽  
Contrast Medium ◽  
Low Dose ◽  
Pulmonary Angiography ◽  
Ct Pulmonary Angiography ◽  
Low Contrast ◽  
Low Contrast Medium

Background: The aim of this study is to perform a systematic review of the feasibility and clinical application of double low-dose CT pulmonary angiography (CTPA) in the diagnosis of patients with suspected pulmonary embolism. Discussion: A total of 13 studies were found to meet selection criteria reporting both low radiation dose (70 or 80 kVp versus 100 or 120 kVp) and low contrast medium dose CTPA protocols. Lowdose CTPA resulted in radiation dose reduction from 29.6% to 87.5% in 12 studies (range: 0.4 to 23.5 mSv), while in one study, radiation dose was increased in the dual-energy CT group when compared to the standard 120 kVp group. CTPA with use of low contrast medium volume (range: 20 to 75 ml) was compared to standard CTPA (range: 50 to 101 ml) in 12 studies with reduction between 25 and 67%, while in the remaining study, low iodine concentration was used with 23% dose reduction achieved. Quantitative assessment of image quality (in terms of signal-to-noise ratio and contrast-to-noise ratio) showed that low-dose CTPA was associated with higher, lower and no change in image quality in 3, 3 and 6 studies, respectively when compared to the standard CTPA protocol. The subjective assessment indicated similar image quality in 11 studies between low-dose and standard CTPA groups, and improved image quality in 1 study with low-dose CTPA. Conclusion: This review shows that double low-dose CTPA is feasible in the diagnosis of pulmonary embolism with significant reductions in both radiation and contrast medium doses, without compromising diagnostic image quality.

scholarly journals Split-filter dual-energy CT pulmonary angiography for the diagnosis of acute pulmonary embolism: a study on image quality and radiation dose

2021 ◽  
Vol 11 (5) ◽  
pp. 1817-1827
Author(s):  
Bernhard Petritsch ◽  
Pauline Pannenbecker ◽  
Andreas M. Weng ◽  
Jan-Peter Grunz ◽  
Simon Veldhoen ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Image Quality ◽  
Radiation Dose ◽  
Acute Pulmonary Embolism ◽  
Pulmonary Angiography ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Ct Pulmonary Angiography

scholarly journals Effect of Lowering Tube Potential and Increase Iodine Concentration of Contrast Medium on Radiation Dose and Image Quality in Computed Tomography Pulmonary Angiography Procedure: A Phantom Study

2021 ◽  
Vol 47 (3) ◽  
pp. 1211-1224
Author(s):  
Justin E Ngaile ◽  
Peter K Msaki ◽  
Evarist M Kahuluda ◽  
Furaha M Chuma ◽  
Jerome M Mwimanzi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Image Quality ◽  
Radiation Dose ◽  
Contrast Medium ◽  
Iodine Concentration ◽  
Pulmonary Angiography ◽  
Computed Tomography Pulmonary Angiography ◽  
Iodinated Contrast ◽  
Tube Potential ◽  
Tube Current

The aim of the study was to examine the effect of lowering tube potential and increase iodine concentration on image quality and radiation dose in computed tomography pulmonary angiography procedure. The pulmonary arteries were simulated by three syringes. The syringes were filled with 1:10 diluted solutions of 300 mg, 350 mg and 370 mg of iodine per millilitre concentration in three water-filled phantoms simulating thin, intermediate and thick patients. The phantoms were scanned at 80 kVp, 110 kVp and 130 kVp and 0.6 second rotation time using a 16 slice computed tomography (CT) scanner. The tube current was either fixed at 80, 100, 200, 250 and 300 mA or automatically adjusted with quality reference tube current-time product (mAsQR). In comparison with 130 kVp, images acquired at 80 kVp and 110 kVp, respectively, showed 76.2% to 99% and 19% to 26% enhancement in CT attenuation of iodinated contrast material. A volume CT dose index (CTDIvol) reduction by 35.3% was attained in small phantom with the use of 80 kVp, while in the medium phantom, a CTDIvol reduction by 29.9% was attained with the use of 110 kVp instead of 130 kVp. In light of the above, lowering tube potential and increase iodinated CM could substantially reduce the dose to small-sized adults and children. Keywords: Angiography; Computed tomography; Low tube potential; Iodinated contrast medium; Radiation dose

Single- and dual-energy CT pulmonary angiography using second- and third-generation dual-source CT systems: comparison of radiation dose and image quality

2019 ◽  
Vol 29 (9) ◽  
pp. 4603-4612 ◽  
Author(s):  
Lukas Lenga ◽  
Franziska Trapp ◽  
Moritz H. Albrecht ◽  
Julian L. Wichmann ◽  
Addison A. Johnson ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Pulmonary Angiography ◽  
Dual Energy ◽  
Dual Energy Ct ◽  
Third Generation ◽  
Dual Source Ct ◽  
Ct Pulmonary Angiography ◽  
Dual Source

Performance of Low-Dose Perfusion Scintigraphy and CT Pulmonary Angiography for Pulmonary Embolism in Pregnancy

CHEST Journal ◽  
2018 ◽  
Vol 153 (1) ◽  
pp. 152-160 ◽  
Author(s):  
Jean-Ju Sheen ◽  
Linda B. Haramati ◽  
Anna Natenzon ◽  
Hong Ma ◽  
Pamela Tropper ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Low Dose ◽  
Pulmonary Angiography ◽  
Ct Pulmonary Angiography ◽  
Perfusion Scintigraphy ◽  
In Pregnancy

scholarly journals Effect of iterative reconstruction algorithm levels on noise index and figure-of-merit in CT pulmonary angiography examinations

2020 ◽  
Vol 28 (5) ◽  
pp. 893-903
Author(s):  
H.H. Harun ◽  
M.K.A. Karim ◽  
Z. Abbas ◽  
A. Sabarudin ◽  
S.C. Muniandy ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Pulmonary Artery ◽  
Iterative Reconstruction ◽  
Figure Of Merit ◽  
Pulmonary Angiography ◽  
Volume Data ◽  
Ct Pulmonary Angiography ◽  
Increase With Increase ◽  
The Mean

PURPOSE: To evaluate the influence of iterative reconstruction (IR) levels on Computed Tomography (CT) image quality and to establish Figure of Merit (FOM) value for CT Pulmonary Angiography (CTPA) examinations. METHODS: Images of 31 adult patients who underwent CTPA examinations in our institution from March to April 2019 were retrospectively collected. Other data, such as scanning parameters, radiation dose and body habitus information from the subjects were also recorded. Six different levels of IR were applied to the volume data of the subjects. Five circles of the region of interest (ROI) were drawn in five different arteries namely, pulmonary trunk, right pulmonary artery, left pulmonary artery, ascending aorta and descending aorta. The mean Signal-to-noise ratio (SNR) was obtained, and the FOM was calculated in a fraction of the SNR2 divided by volume-weighted CT dose index (CTDIvol) and SNR2 divided by the size-specific dose estimates (SSDE). RESULTS: Overall, we observed that the mean value of CTDIvol and SSDE were 13.79±7.72 mGy and 17.25±8.92 mGy, respectively. Notably, SNR values significantly increase with increase of the IR level (p < 0.05). There are also significant differences (p < 0.05) in the FOM for both SNR2/SSDE and SNR2/CTDIvol attained in different IR levels. CONCLUSION: We successfully evaluate the value of radiation dose and image quality performance and set up a figure of merit for both parameters to further verify scanning protocols by radiology personnel.

Low-dose CT angiography of the abdominal aorta and reduced contrast medium volume: Assessment of image quality and radiation dose

2016 ◽  
Vol 71 (1) ◽  
pp. 64-73 ◽  
Author(s):  
W.H. Nijhof ◽  
E.J.M. Baltussen ◽  
I.M.J. Kant ◽  
G.J. Jager ◽  
C.H. Slump ◽  
...  
Keyword(s):  
Image Quality ◽  
Radiation Dose ◽  
Contrast Medium ◽  
Ct Angiography ◽  
Abdominal Aorta ◽  
Low Dose ◽  
Low Dose Ct ◽  
Volume Assessment

scholarly journals Prospective randomised comparison of diagnostic confidence and image quality with normal-dose and low-dose CT pulmonary angiography at various body weights

2014 ◽  
Vol 24 (8) ◽  
pp. 1868-1877 ◽  
Author(s):  
Zsolt Szucs-Farkas ◽  
Boglarka Megyeri ◽  
Andreas Christe ◽  
Peter Vock ◽  
Johannes T. Heverhagen ◽  
...  
Keyword(s):  
Image Quality ◽  
Low Dose ◽  
Pulmonary Angiography ◽  
Ct Pulmonary Angiography ◽  
Diagnostic Confidence ◽  
Normal Dose ◽  
Low Dose Ct ◽  
Body Weights
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