Role of lipid Nanoparticles in COVID-19 inrepurposing drugs and vaccines

2021 ◽  
Vol 17 ◽  
Author(s):  
Rajesh Basnet ◽  
Til Bahadur Basnet ◽  
Buddha Bahadur Basnet ◽  
Sandhya Khadka ◽  
Sanjeep Sapkota
Keyword(s):  
Public Health ◽  
Lipid Nanoparticles ◽  
Antiviral Drugs ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Rigorous Testing ◽  
Technical Solutions ◽  
New Strategies ◽  
Lengthy Process

Background: The spread of new coronavirus 2019, the causative agent of viral pneumonia documented in Wuhan, brought a recent public health crisis globally. The best solution to overcome this pandemic is developing suitable and effective vaccines and therapeutics. However, discovering and creating a new drug is a lengthy process requiring rigorous testing and validation. Objective: Despite many newly discovered and old repurposed COVID-19 drugs under clinical trial, more emphasis should be given to research on COVID-19 NPs-based medicines, which could improve the efficacy of antiviral drugs to reduce their side effects. The use of NPs as carriers can reduce the frequency and duration of drug ingestion, enhance approved antiviral therapeutics' effectiveness, and overcome their limitations, such as low bioavailability. Besides, they can play a crucial role in fighting against the COVID-19 pandemic. In this regard, nanotechnology provides new opportunities to develop new strategies for preventing, diagnosing, and treating COVID-19. Conclusion: This review highlighted the importance of NMs-based technical solutions in antiviral drugs for testing against the SARS-CoV-2 virus emergencies in the form of nanotherapeutics.

Anticipating on a post covid-19 world and the pivotal role of science and technology

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Saeed Khan ◽  
Tusha Sharma ◽  
Basu Dev Banerjee ◽  
Scotty Branch ◽  
Shea Harrelson
Keyword(s):  
Public Health ◽  
Pivotal Role ◽  
Public Healthcare ◽  
Healthcare Organizations ◽  
Health Crisis ◽  
Outbreak Management ◽  
The Public ◽  
Public Health Crisis ◽  
Future Outbreak

: Currently, Coronavirus disease 2019 (COVID-19) has transformed into a severe public health crisis and wreaking havoc worldwide. The ongoing pandemic has exposed the public healthcare system's weaknesses and highlighted the urgent need for investments in scientific programs and policies. A comprehensive program utilizing the science and technologydriven strategies combined with well-resourced healthcare organizations appears to be essential for current and future outbreak management.

Bhutan: The Role of the Constitutional Monarch in a Public Health Crisis

2021 ◽  
pp. 279-292
Author(s):  
Sonam Tshering ◽  
Nima Dorji
Keyword(s):  
Public Health ◽  
Artificial Intelligence ◽  
Health Crisis ◽  
Drug Smuggling ◽  
Personal Involvement ◽  
Public Health Crisis ◽  
The People ◽  
Long Run ◽  
The Government

This chapter reflects on Bhutan’s response to the Covid-19 pandemic. The people’s trust and confidence in the leadership of His Majesty the King, their government, strong Buddhist values to help each other, and the conscience of unity and solidarity proved their foremost strength in containing this pandemic as a nation. The king’s personal involvement helped guide, motivate, and encourage compliance with and support for the government’s response. However, Bhutan faced several challenges during the pandemic. Though most of the people are united, there are outliers who took advantage of the situation; there are reported cases of drug smuggling and one case of a person who escaped from quarantine. The government responded by increasing border patrols. In the long run, other solutions could be considered: installing a smart wall—using drones, sensors, and artificial intelligence patrols—would give Bhutan more control over its borders in the context of another epidemic while also enabling the government to better control smuggling.

scholarly journals The role of spirituality in the COVID-19 pandemic: a spiritual hotline project

2020 ◽  
Vol 42 (4) ◽  
pp. 855-856 ◽  
Author(s):  
Marcus Renato Castro Ribeiro ◽  
Rodolfo Furlan Damiano ◽  
Ricardo Marujo ◽  
Fabio Nasri ◽  
Giancarlo Lucchetti
Keyword(s):  
Public Health ◽  
Social Isolation ◽  
Religious Affiliation ◽  
Letters To The Editor ◽  
Health Crisis ◽  
Frontline Workers ◽  
Public Health Crisis ◽  
The Social ◽  
Important Approach

Abstract Recent correspondence letters to the editor of this journal pointed out to the need of implementing psychological support during the pandemic and post-pandemic period to both general and frontline workers. Especially, they highlighted the importance of religious/spiritual interventions in order to provide an integral and holistic care. In this perspective, an important consequence of the social isolation is the closure of churches and the suspension of religious meetings in order to avoid agglomeration and contagion. However, although this is a very important approach in terms of public health, a question is raised: how to promote spiritual care and help spiritual/religious individuals to cope with their problems while maintaining compliance with social isolation? To address this question, we report the Spiritual Hotline Project, a project designed by many Brazilian healthcare workers intended to give spiritual and religious assistance to people with different cultural background. So far, the hotline was able to assist people from different parts of the world, including Brazil and Portugal as well as with different religious affiliation, in order to provide a spiritual comfort and care during this public health crisis.

scholarly journals Effects of scientific literacy on attitudes toward COVID-19 vaccinations and preventive behaviors: A pre-registered study

2021 ◽  
Author(s):  
Kosuke Motoki ◽  
Toshiki Saito ◽  
Yuji Takano
Keyword(s):  
Public Health ◽  
Scientific Literacy ◽  
Global Public Health ◽  
Preventive Behaviors ◽  
Negative Attitudes ◽  
Health Crisis ◽  
Vaccine Administration ◽  
Subjective Knowledge ◽  
Public Health Crisis

The ongoing COVID-19 pandemic, which began in early 2020, is a global public health crisis. To prevent the spread of COVID-19, it is necessary to promote vaccine administration and preventive behaviors (e.g., mask, handwashing, social distancing). However, some people have negative attitudes toward vaccine administration and preventive behaviors. The present study investigated how scientific literacy and perceived understanding of COVID-19 influence attitudes toward COVID-19 vaccinations and preventive behaviors. The findings demonstrated that both scientific literacy and perceived understanding of COVID-19 vaccines were positively associated with attitudes toward COVID-19 vaccines. Additionally, perceived understanding of COVID-19 preventive behaviors (but not scientific literacy) was positively associated with attitudes toward/practice of COVID-19 preventive behaviors. Collectively, our findings revealed the role of cognitive factors in preventing the global public health crisis and demonstrated the effects of objective and subjective knowledge on attitudes toward COVID-19 vaccinations and preventive behaviors.

scholarly journals Firearm violence in the USA: a frank discussion on an American public health crisis—The Kansas City Firearm Violence Symposium

2019 ◽  
Vol 4 (1) ◽  
pp. e000359 ◽  
Author(s):  
Robert D Winfield ◽  
Marie Crandall ◽  
Brian H Williams ◽  
Joseph Victor Sakran ◽  
Kathy Shorr ◽  
...  
Keyword(s):  
Public Health ◽  
Kansas City ◽  
Gun Violence ◽  
Diverse Population ◽  
Core Component ◽  
Health Crisis ◽  
Public Health Crisis ◽  
Firearm Violence ◽  
The Usa

Kansas City is a microcosm for USA. Although Kansas City shows a relatively diverse population, it is one that is segregated along the lines of race and income. This is an inequity that is common to all cities across the country. With this inequity comes unequal opportunity to survive and to thrive. Firearm violence is a core component of this societal inequity. In this article, we present the proceedings of the 2019 Kansas City Firearm Violence Symposium, where distinguished experts in trauma convened to share their experience, evidence and voices of gun violence—directly and indirectly. There were discussions on topics such as the human toll of gun violence, the role of structural violence in its perpetuation, the intersectional nature of race with both violence and medical care, and guidance on measures that could be taken to advocate for the reduction and elimination of gun violence. This was a symposium that started a country-wide conversation between academia, healthcare, survivors and the community on the most pressing public health crisis facing USA today.

Sign in / Sign up

Export Citation Format

Share Document