Current Directions in Non-Invasive Low Intensity Electric Brain Stimulation for Depressive Disorder

2014 ◽  
Vol 13 (6) ◽  
pp. 945-952 ◽  
Author(s):  
Dennis Schutter ◽  
Alexander Sack
Keyword(s):  
Depressive Disorder ◽  
Brain Stimulation ◽  
Non Invasive ◽  
Low Intensity ◽  
Electric Brain Stimulation

scholarly journals A Systematic Review of Non-Invasive Brain Stimulation Therapies and Cardiovascular Risk: Implications for the Treatment of Major Depressive Disorder

2012 ◽  
Vol 3 ◽  
Author(s):  
Leonardo Augusto Negreiros Parente Capela Sampaio ◽  
Renerio Fraguas ◽  
Paulo Andrade Lotufo ◽  
Isabela Martins Benseñor ◽  
André Russowsky Brunoni
Keyword(s):  
Systematic Review ◽  
Major Depressive Disorder ◽  
Cardiovascular Risk ◽  
Depressive Disorder ◽  
Brain Stimulation ◽  
Major Depressive ◽  
Non Invasive

scholarly journals Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation

2018 ◽  
Author(s):  
Nya Mehnwolo Boayue ◽  
Gábor Csifcsák ◽  
Oula Puonti ◽  
Axel Thielscher ◽  
Matthias Mittner
Keyword(s):  
Electric Fields ◽  
Brain Stimulation ◽  
Brain Anatomy ◽  
Imaging Data ◽  
Structural Variations ◽  
Major Depressive ◽  
Non Invasive ◽  
The Past ◽  
Dorsolateral Prefrontal ◽  
Electric Brain Stimulation

During the past decade, it became clear that the electric field elicited by non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are substantially influenced by variations in individual head and brain anatomy. In addition to structural variations in the healthy, several psychiatric disorders are characterized by anatomical alterations that are likely to further constrain the intracerebral effects of NIBS. Here, we present high-resolution realistic head models derived from structural magnetic resonance imaging data of 19 healthy adults and 19 patients diagnosed with major depressive disorder (MDD). By using a freely available software package for modelling the electric fields induced by different NIBS protocols, we show that our head models are well-suited for assessing inter-individual and between-group variability in the magnitude and focality of tDCS-induced electric fields for two protocols targeting the left dorsolateral prefrontal cortex.

scholarly journals Head models of healthy and depressed adults for simulating the electric fields of non-invasive electric brain stimulation

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 704 ◽  
Author(s):  
Nya Mehnwolo Boayue ◽  
Gábor Csifcsák ◽  
Oula Puonti ◽  
Axel Thielscher ◽  
Matthias Mittner
Keyword(s):  
Electric Fields ◽  
Brain Stimulation ◽  
Brain Anatomy ◽  
Imaging Data ◽  
Structural Variations ◽  
Major Depressive ◽  
Non Invasive ◽  
The Past ◽  
Dorsolateral Prefrontal ◽  
Electric Brain Stimulation

During the past decade, it became clear that the electric field elicited by non-invasive brain stimulation (NIBS) techniques such as transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS) are substantially influenced by variations in individual head and brain anatomy. In addition to structural variations in the healthy, several psychiatric disorders are characterized by anatomical alterations that are likely to further constrain the intracerebral effects of NIBS. Here, we present high-resolution realistic head models derived from structural magnetic resonance imaging data of 19 healthy adults and 19 patients diagnosed with major depressive disorder (MDD). By using a freely available software package for modelling the electric fields induced by different NIBS protocols, we show that our head models are well-suited for assessing inter-individual and between-group variability in the magnitude and focality of tDCS-induced electric fields for two protocols targeting the left dorsolateral prefrontal cortex.

Does Non-Invasive Brain Stimulation Improve Cognition in Major Depressive Disorder? A Systematic Review

2015 ◽  
Vol 13 (10) ◽  
pp. 1759-1769 ◽  
Author(s):  
Gabriel Tortella ◽  
Priscila Selingardi ◽  
Marina Moreno ◽  
Beatriz Veronezi ◽  
Andre Brunoni
Keyword(s):  
Systematic Review ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Brain Stimulation ◽  
Major Depressive ◽  
Non Invasive

scholarly journals The effect and mechanism of low intensity focused ultrasound in the treatment of Parkinson's disease

2021 ◽  
Author(s):  
Ling Long ◽  
yunxiao zhong ◽  
Xiaodong Cai ◽  
Jinchi Liao ◽  
Xu Liu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Brain Stimulation ◽  
Focused Ultrasound ◽  
Motor Symptoms ◽  
Future Outlook ◽  
Non Invasive ◽  
Low Intensity ◽  
Current State ◽  
Stimulation Method

ABSTRACT Parkinson’s disease (PD) is a chronic, progressive, neurodegenerative disease. A new brain-stimulation method, low-intensity focused ultrasound (LIFUS), has been shown to improve PD-associated motor symptoms and permeabilize the blood-brain barrier. LIFUS is especially attractive due to its non-invasive nature and represents a treatment option that could be incorporated into the future treatment of neurodegenerative diseases, including PD. In this paper, we describe the current state and future outlook of LIFUS for the treatment of PD. We also focus on the stimulation principles that underly the effects of LIFUS during PD treatment. The safety and limitations of LIFUS are also discussed.

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