Assessment of Trabecular Bone During Dental Implant Planning using Cone-beam Computed Tomography with High-resolution Parameters

Background: Cone-Beam Computed Tomography (CBCT) with high-resolution parameters may provide an acceptable resolution for bone assessment. Objectives: The purpose of this study is to assess trabecular bone using two cone-beam computed tomography (CBCT) devices with high-resolution parameters in comparison to micro-computed tomography (µCT). Methods: Bone samples (n=8) were acquired from dry mandibles and scanned by two CBCT devices: 1) VV (Veraview R100, Morita; FOV 4x4, 75kV, 9mA, voxel size 0.125µm); and PR (Prexion 3D, Prexion; FOV 5x5, 90kV, 4mA, 37s, voxel size 108µm). Gold-standard images were acquired using µCT (SkyScan 1272; Bruker; 80kV, 125mA, voxel size 16µm). Morphometric parameters (BvTv- Bone Volume Fraction, BsBv- Trabecular specific surface, TbTh- Trabecular thickness and TbSp- Trabecular separation) were measured. Statistical analysis was performed within ANOVA, Spearman Correlation test and Bland-Altmann plots with a statistical significance level at p=0.05. Results: CBCT devices showed similar BvTv values in comparison to µCT. No statistical difference was found for BvTv parameters assessed by CBCT devices and µCT. BsBv values were underestimated by CBCT devices (p<0.01), whereas TbTh and TbSp values were overestimated by them (p<0.01). Positive correlations were found between VV and µCT measurements for BvTv (r2= 0.65, p=0.00), such as between PR and µCT measurements for TbSp (r2= 0.50, p=0.04). For BsBv measurements, PR was negatively correlated with µCT (r2= -0.643, p=0.01). Conclusion: The evaluated CBCT device was able to assess trabecular bone. However, bone parameters were under or overestimated in comparison to µCT.

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Comparison of the different voxel sizes in the estimation of peri-implant fenestration defects using cone beam computed tomography: an ex vivo study

International Journal of Implant Dentistry ◽

10.1186/s40729-020-00254-2 ◽

2020 ◽

Vol 6 (1) ◽

Author(s):

Mehmet Hakan Kurt ◽

Nilsun Bağış ◽

Cengiz Evli ◽

Cemal Atakan ◽

Kaan Orhan

Keyword(s):

Computed Tomography ◽

Cone Beam Computed Tomography ◽

Ex Vivo ◽

Statistical Significance ◽

Area Under The Curve ◽

Titanium Implant ◽

Bone Defects ◽

Titanium Implants ◽

Cone Beam ◽

Voxel Size

Abstract Background To examine the influence of voxel sizes to detect of peri-implant fenestration defects on cone beam computed tomography (CBCT) images. Materials and methods This study performed with three sheep heads both maxilla and mandible and two types of dental implant type 1 zirconium implant (Zr40) (n = 6) and type 2 titanium implant (Ti22) (n = 10). A total of 14 peri-implant fenestrations (8 buccal surfaces, 6 palatal/lingual surface) were created while 18 surfaces (8 buccal, 10 palatal/lingual) were free of fenestrations. Three observers have evaluated the images of fenestration at each site. Images obtained with 0.75 mm3, 0.100 mm3, 0.150 mm3, 0.200 mm3, and 0.400 mm3 voxel sizes. For intra- and inter-observer agreements for each voxel size, Kappa coefficients were calculated. Results Intra- and inter-observer kappa values were the highest for 0.150 mm3, and the lowest in 0.75 mm3 and 0.400 mm3 voxel sizes for all types of implants. The highest area under the curve (AUC) values were found higher for the scan mode of 0.150 mm3, whereas lower AUC values were found for the voxel size for 0.400 mm3. Titanium implants had higher AUC values than zirconium with the statistical significance for all voxel sizes (p ≤ 0.05). Conclusion A voxel size of 0.150 mm3 can be used to detect peri-implant fenestration bone defects. CBCT is the most reliable diagnostic tool for peri-implant fenestration bone defects.

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Super-resolution and learned perceptual loss allows high-resolution imaging of trabecular bone with clinical cone beam computed tomography

Osteoarthritis and Cartilage ◽

10.1016/j.joca.2021.02.441 ◽

2021 ◽

Vol 29 ◽

pp. S338-S339

Author(s):

S.J. Rytky ◽

M.A. Finnilä ◽

S.K. Karhula ◽

M. Valkealahti ◽

P. Lehenkari ◽

...

Keyword(s):

Computed Tomography ◽

High Resolution ◽

Trabecular Bone ◽

Cone Beam Computed Tomography ◽

Super Resolution ◽

Cone Beam ◽

High Resolution Imaging ◽

Resolution Imaging

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The use of high-resolution computed tomography to explore age-related trabecular change in human ribs

10.1101/2021.07.12.452053 ◽

2021 ◽

Author(s):

Sophia Mavroudas ◽

Victoria M Dominguez

Keyword(s):

Computed Tomography ◽

High Resolution ◽

Trabecular Bone ◽

Cortical Bone ◽

Volume Fraction ◽

Bone Volume ◽

3D Analysis ◽

High Resolution Computed Tomography ◽

Trabecular Thickness ◽

Age Related

High-resolution computed tomography was used to explore age-related trabecular change in male human ribs ranging in age from 20–95 years (Mean=55 years, SD=21.634 years) from the Texas State Donated Skeletal Collection (TXSTDSC). Two regions of interest (ROIs), midshaft (50%) and anterior (75%) were extracted from each scan to analyze age-related trabecular change. Dragonfly V4.1 was used to isolate cortical bone volumes of interest (VOIs) and three trabecular VOIs for each ROI; one each along the cutaneous cortex, the center of the medullary cavity, and the pleural cortex. Each trabecular VOI was analyzed for bone volume fraction (BV/TV), trabecular thickness (TbTh), trabecular spacing (TbSp), connectivity density (Conn.D), and degree of anisotropy (DA), within and between the 50 and 75% ROIs. Overall, the cutaneous VOIs at both the 50% and 75% ROIs exhibited greater BV/TV, TbTh, and Conn.D when compared to the center and pleural VOIs. All results are consistent with expected biomechanical strain on human ribs. Both trabecular variables and cortical bone volume are only weakly associated with age. These results show that 3D analysis of trabecular bone volume does not improve visualization or understanding of trabecular bone changes with age over traditional 2D methods. Future research should incorporate female samples to explore sex-related trabecular change variation.

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Effect of Scanning Resolution on the Prediction of Trabecular Bone Microarchitectures Using Dental Cone Beam Computed Tomography

Diagnostics ◽

10.3390/diagnostics10060368 ◽

2020 ◽

Vol 10 (6) ◽

pp. 368

Author(s):

Ming-Tzu Tsai ◽

Rong-Ting He ◽

Heng-Li Huang ◽

Ming-Gene Tu ◽

Jui-Ting Hsu

Keyword(s):

Computed Tomography ◽

Trabecular Bone ◽

Bone Quality ◽

Cone Beam Computed Tomography ◽

Correlation Coefficients ◽

Experimental Results ◽

Cone Beam ◽

Micro Ct ◽

Trabecular Thickness ◽

Dental Implantation

Assessing bone quality and quantity at the location of dental implants before dental implantation is crucial. In recent years, dental cone-beam computed tomography (dental CBCT) has often been used to assess bone quality and quantity prior to dental implant. However, the effect of scanning resolution on the prediction of trabecular bone microarchitectural parameters (TBMPs) remains unclear. The objective of this study was to examine how dental CBCT with various scanning resolution differs with regard to predicting TBMPs. This study used micro-computed tomography (micro-CT) with 18 μm resolution and dental CBCT with 100 μm and 150 μm resolutions on 28 fresh bovine vertebrae cancellous bone specimens. Subsequently, all images were input into the ImageJ software to measure four TBMPs: bone volume total volume fraction (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), and trabecular separation (Tb.Sp). One-way analysis of variance and Tukey’s test were subsequently used to assess the differences between three scanning modes for the four TBMPs. In addition, correlations between measurement results obtained from micro-CT and dental CBCT with two resolutions were measured. The experimental results indicated that significant differences in four TBMPs were observed between micro-CT and dental CBCT (p < 0.05). The correlation coefficients between BV/TV, Tb.N, and Tb.Sp obtained from micro-CT and from dental CBCT with 100 μm resolution (0.840, 0.739, and 0.820, respectively) were greater than the correlation coefficients between BV/TV, Tb.N, and Tb.Sp obtained from micro-CT and from dental CBCT with 150 μm resolution (0.758, 0.367, and 0.724, respectively). The experimental results revealed that the TBMPs measured with dental CBCT with two resolutions differed from ideal values, but a higher resolution could provide more accurate prediction results, particularly for BV/TV, Tb.N, and Tb.Sp.

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Measurement of trabecular bone parameters with different bone thickness and voxel size in mice using micro CT

Malaysian Journal of Fundamental and Applied Sciences ◽

10.11113/mjfas.v15n2019.1128 ◽

2019 ◽

Vol 15 (1) ◽

pp. 65-68

Author(s):

Nurin Nadzlah Abu Bakar ◽

Basri Saidi ◽

Lyana Shahirah Mohamad Yamin

Keyword(s):

Trabecular Bone ◽

Volume Fraction ◽

Bone Volume ◽

Bone Morphology ◽

Bone Volume Fraction ◽

Voxel Size ◽

Trabecular Thickness ◽

Bone Parameters ◽

Trabecular Separation ◽

Trabecular Number

Micro-CT is one of the best modalities in assessing bone morphology and microarchitecture in small animal models. Voxel size is directly related to the image resolution as it influences the bone morphology results. The purpose of this study was to assess the effects of t different thicknesses of structures on the trabecular bone qualitative parameters. It was also to find out the most appropriate voxel size when scanning a certain or specific body part with different thicknesses. Five BALB-C breed mice carcasses were scanned using two different voxel sizes of 18 and 35 µm. The scanning acquisition times were recorded to be compared and the trabecular bone parameters measurements were taken. Both trabecular number and trabecular separation were increased in thicker structures meanwhile bone volume fraction and trabecular thickness values were inconsistent with the increment of the structure thickness. The bone volume fraction, trabecular thickness and trabecular separation were higher in larger voxel size and vice versa for trabecular number. The scanning acquisition time has no apparent correlation with the trabecular bone parameters. The thickness of the bone structure did affect trabecular number and trabecular separation significantly but less affecting bone volume fraction and trabecular thickness. All trabecular bone parameters were found affected by the size of scanning voxel size used. The usage of 35 µm voxel was more recommended than 18 µm to save time and give out less radiation dose to specimen unless the detailed features of the trabecular pattern was very important.

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Comparison between Micro-Computed Tomography and Cone-Beam Computed Tomography in the Assessment of Bone Quality and a Long-Term Volumetric Study of the Augmented Sinus Grafted with an Albumin Impregnated Allograft

Journal of Clinical Medicine ◽

10.3390/jcm9020303 ◽

2020 ◽

Vol 9 (2) ◽

pp. 303 ◽

Cited By ~ 1

Author(s):

Márton Kivovics ◽

Bence Tamás Szabó ◽

Orsolya Németh ◽

Dóra Iványi ◽

Bálint Trimmel ◽

...

Keyword(s):

Computed Tomography ◽

Bone Quality ◽

Cone Beam Computed Tomography ◽

Volume Fraction ◽

Cone Beam ◽

Micro Ct ◽

Trabecular Thickness ◽

Implant Placement ◽

Ct Data

The purpose of our study was to compare micromorphometric data obtained by cone-beam computed-tomography (CBCT) and microcomputed-tomography (micro-CT) of the augmented sinus and to evaluate the long-term stability of the bone gain achieved using BoneAlbumin. Sinus lifts, and after 6-months, healing bone-biopsy and implant placement were carried out. Specimens were analyzed by micro-CT. A total of 16 samples were collected from nine patients (mean age 54.7 ± 6.5 years). Pre-, postoperative, and 3-year control CBCT-data were registered to determine from where the biopsy samples were harvested. Micromorphometric variables were calculated from the micro-CT- and CBCT-data, and their correlation was determined by Spearman’s test. The volume of augmented bone was calculated at the time of implant placement and after 3 years. A positive correlation was found between bone-volume fraction, trabecular-separation, open-, and total-porosity, while a negative correlation was found between trabecular-thickness obtained from CBCT- and micro-CT-data (p < 0.05). Mean volumetric reduction of 39.28% (11.88–60.02%) was observed. Correlation of CBCT- and micro-CT-data suggested that micromorphometric analysis of CBCT reconstructions of the augmented sinuses provided reliable information on the microarchitecture of augmented bone. CBCT as a modality might be adequate in the analysis of bone quality in the augmented sinus. At the 3-year, control sinus grafts showed volumetric stability.

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