A Rare Case of Kawasaki-like Multisystem Inflammatory Syndrome following COVID-19 in an Adult

2021 ◽  
Vol 15 (1) ◽  
pp. 87-91
Author(s):  
Pepijn Van Hove ◽  
Chris Kenyon

In this case report, we describe a Kawasaki-like multisystem inflammatory syndrome (MIS-A) in a 33-year old man that occurred 19 days after a SARS-CoV-2 infection. The main features at presentation were profound myocarditis, bilateral non-purulent conjunctivitis, mediastinal lymphadenopathy, and acute kidney failure and laboratory evidence of hyperinflammation. He received ACE-inhibition and beta-blockers for his heart failure and made a fairly rapid spontaneous recovery over the subsequent 8 days.

2014 ◽  
Vol 24 (2) ◽  
pp. 86-88
Author(s):  
Mohammad Shahidul Islam ◽  
Humayara Tabassum ◽  
Sharah Jahan ◽  
Mohammad Shahin Masud ◽  
Muhammad Al Amin ◽  
...  

Heart failure may present with diverse manifestation. It is far most common cause of bilateral transudative pleural effusion. In very unusual case, it may present with only massive transudative pleural effusion without cardiomegaly and other features of heart failure such as leg odema, tender hepatomegaly or congested liver. We presented a case that present with massive transudative pleural effusion with mediastinal lymphadenopathy evidenced by CT scan of chest and treated successfully with diuretics. DOI: http://dx.doi.org/10.3329/bjmed.v24i2.20223 Bangladesh J Medicine 2013; 24 : 86-88


2019 ◽  
pp. 47-58
Author(s):  
Lina Lozano Lesmes ◽  
Natalia Andrea Quintero Guzmán ◽  
Jenny Lizeth Cuellar Devia ◽  
Edwin Alberto Torres García ◽  
Samuel Arias Valencia

Objetivo: Cuantificar la incidencia y los factores de exposición relacionados con el desarrollo de la insuficiencia renal aguda en pacientes hospitalizados en unidades de cuidados intensivos adulto durante tres meses. Materiales y métodos: se  realizó un estudio epidemiológico de tipo cuantitativo con dos componentes: descriptivo longitudinal y de cohorte histórica, se emplearon los criterios de AKIN, participaron dos instituciones de salud, una de orden privado y otra de orden público.  Resultados: Se incluyeron 186 pacientes, con una edad promedio de  56,2 +/- 20,14 años.  Se encontró una incidencia del 21,6 % (IC 95 % 17-30) de insuficiencia renal aguda y una tasa de incidencia de 29,2 por cada 100 pacientes año exposición. En promedio la elevación de creatinina fue 0,47 mg/dL y el gasto urinario de 0,37 cc/kg/h, los días en ocurrir el evento 3,1 (IC 95 % 2,48-3,74). Se encontró relación estadísticamente significativa entre insuficiencia cardíaca aguda 6,84 días (IC 95 % 4,21-9,48) (p=0,026),   posoperatorios 9,82 días (IC 95 % 8,42-11,2) (p=0,04) y trauma craneoencefálico 4,5 días (IC 95 % 1,56-7,44) (p=0,043) como causas de ingreso y la aparición de insuficiencia renal aguda Conclusiones:  La proporción de incidencia de insuficiencia renal aguda identificada en el presente estudio, es similar a estudios realizados en Colombia, sin embargo, difiere de otros realizados en el exterior. La sepsis fue el diagnóstico con mayor frecuencia entre los pacientes con insuficiencia renal aguda, seguido de la insuficiencia cardíaca aguda. Se encontró significancia estadística en el desarrollo de la insuficiencia renal aguda y la administración de nitroglicerina. Palabras clave: Enfermedad renal, Estudios Epidemiológicos, Cuidados Críticos, Adulto.    Acute kidney failure in critically ill adults from two health care institutions. Abstract Objective: To quantify the incidence and factors of exposure related to the development of acute kidney failure in hospitalized patients in the adult intensive care unit during three months. Materials and methods: An epidemiological study of quantitative type with two components was performed: descriptive longitudinal study and a retrospective cohort study, AKIN criteria were used, two health care institutions (one private and one public) participated. Results: 186 patients were included with an average age of 56.2 +/- 20,14 years. An incidence of 21.6% was found (IC 95 % 17-30) of acute kidney failure and a rate of incidence of 29.2 for every 100 patients / year of exposure. On average the creatinine elevation was of 0.47 mg/dL and the urine output was of 0.37 cc/kg/h, days of event occurrence 3.1 (IC 95 % 2.48-3.74). A significant statistical relationship was found between acute heart failure 6.84 days (IC 95% 4.21-9.48) (p=0.026), post-operatives 9.82 days (IC 95 % 8.42-11.2) (p=0.04) and traumatic brain injury 4.5 days (IC 95 % 1.56-7.44) (p=0.043), as causes of admission and appearance of acute kidney failure. Conclusions:  The incidence proportion of acute kidney failure identified in the present study, is similar to other studies performed in Colombia, however, it differs from studies performed in other countries. Sepsis was the most frequent diagnosis among patients with acute kidney failure, followed by acute heart failure. Statistical significance was found in the development of acute kidney failure and the intake of nitroglycerin. Keywords: Kidney failure, Epidemiological studies, Critical care, Adult.    Insuficiência renal aguda em adultos criticamente doentes em duas instituições hospitalares   Resumo Objetivo: Quantificar a incidência e os fatores de exposição relacionados com o desenvolvimento da Insuficiência Renal Aguda (IRA) em pacientes adultos hospitalizados em unidades de terapia intensiva durante três meses. Materiais e métodos: realizou-se um estudo epidemiológico de tipo quantitativo com dois componentes: descritivo longitudinal e de coorte histórica, empregaram-se os critérios de AKIN (Acute Kidney Injury Network), participaram duas instituições de saúde, uma de ordem privado e outra de ordem pública.  Resultados: Incluíram-se 186 pacientes, com uma idade média de 56,2 ± 20,14 anos. Encontrou-se uma incidência do 21,6 % (IC 95 % 17-30) de insuficiência renal aguda e uma taxa de incidência de 29,2 por cada 100 pacientes ano exposição. Em média a elevação de creatinina foi de 0,47 mg/dL e o gasto urinário de 0,37 cc/kg/h, os dias em ocorrer o evento 3,1 (IC 95 % 2,48-3,74). Encontrou-se relação estatisticamente significativa entre insuficiência cardíaca aguda (ICA) 6,84 dias (IC 95 % 4,21-9,48) (p=0,026),   pós-operatórios 9,82 dias (IC 95 % 8,42-11,2) (p=0,04) e traumatismo cranioencefálico (TCE) 4,5 dias (IC 95 % 1,56-7,44) (p=0,043) como causas de ingresso e a aparição de insuficiência renal aguda Conclusões:  A proporção de incidência de insuficiência renal aguda identificada no presente estudo, é similar a estudos realizados na Colômbia, no entanto, difere de outros realizados no exterior. A sepse foi o diagnóstico com maior frequência entre os pacientes com insuficiência renal aguda, seguido da insuficiência cardíaca aguda. Obteve-se significância estadística no desenvolvimento da insuficiência renal aguda e a administração de nitroglicerina. Palavras-chave: Adulto, Cuidados Críticos, Doença renal, Estudos Epidemiológicos. 


2020 ◽  
Vol 5 (3) ◽  
pp. S384
Author(s):  
M. SABAH ◽  
F. Jabrane ◽  
N. Chehab ◽  
M.A. Khalfaoui ◽  
H. El oury ◽  
...  

2017 ◽  
Vol 11 (1) ◽  
pp. 201-206
Author(s):  
Molham Abdulsamad ◽  
Naeem Abbas ◽  
Harish Patel ◽  
Bhavna Balar ◽  
Misbahuddin Khaja

Multiple myeloma (MM) is a neoplastic proliferation of plasma cells with overproduction of monoclonal immunoglobulins and infiltration into the bone and other organs. Ascites can develop in patients with lymphoproliferative and solid malignancies involving the peritoneum. However, ascites is unusual in MM and rarely the initial presenting sign or symptom. The development of ascites can be due to peritoneal infiltration or secondary to hepatic involvement, heart failure, or kidney failure. Ascites in MM reflects a more aggressive stage, and the reported prognosis is poor, with a median survival of 1–2 months. Here we present a rare case of immunoglobulin A lambda MM presenting with massive myelomatous ascites.


2021 ◽  
Vol 61 (5) ◽  
pp. 283-6
Author(s):  
Ririe Fachrina Malisie

A number of coronavirus disease-19 (COVID-19)–related myocarditis cases have recently been reported. Myocarditis is an inflammatory disease of the heart characterized by inflammatory infiltrates and myocardial injury without an ischemic cause.1 While multiple etiologies exist, the major cause appears to be related to viral illnesses. Clinical presentations vary from asymptomatic to sudden unexpected death.2 Acute heart failure due to COVID-19-related acute myocarditis has been associated with multisystem inflammatory syndrome, mimicking Kawasaki disease. 3 Here, we report a case of a 1-month old girl with reactive anti-COVID–19 IgG, presenting with arrhythmia following the shortness of breath during hospitalization. Respiratory distress and myocarditis progressed to multiple organ failure and the patient died on her third day in the PICU.


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