Advancement in nano pharmaceutical formulation and their biomedical use

: Nanoparticles and modified nanoparticles are used in biological and medical sciences as liposomes, polymeric micelles, block ionomer complexes, dendrimers, inorganic and organic nanoparticles. Nanoparticles and surface modified nanoparticles are showed good stability and water solubility and can be used efficiently as drug delivery carrier. This paper summarized the advancement in nanoparticles/surface modified nanoparticles and patents based on them.

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Cross-linked Polymeric Micelles based on Block Ionomer Complexes

Mendeleev Communications ◽

10.1016/j.mencom.2013.07.001 ◽

2013 ◽

Vol 23 (4) ◽

pp. 179-186 ◽

Cited By ~ 26

Author(s):

Jong Oh Kim ◽

Thiruganesh Ramasamy ◽

Chul Soon Yong ◽

Natalia V. Nukolov ◽

Tatiana K. Bronich ◽

...

Keyword(s):

Polymeric Micelles ◽

Block Ionomer Complexes ◽

Block Ionomer

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Synthesis of mesoporous hollow silica nanospheres using polymeric micelles as template and their application as a drug-delivery carrier

Dalton Transactions ◽

10.1039/c3dt51267c ◽

2013 ◽

Vol 42 (37) ◽

pp. 13381 ◽

Cited By ~ 51

Author(s):

Manickam Sasidharan ◽

Haruna Zenibana ◽

Mahasweta Nandi ◽

Asim Bhaumik ◽

Kenichi Nakashima

Keyword(s):

Drug Delivery ◽

Polymeric Micelles ◽

Silica Nanospheres ◽

Hollow Silica ◽

Drug Delivery Carrier ◽

Hollow Silica Nanospheres

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Block ionomer complexes of PEG-block-poly(4-vinylbenzylphosphonate) and cationic surfactants as highly stable, pH responsive drug delivery system

Journal of Controlled Release ◽

10.1016/j.jconrel.2012.04.027 ◽

2012 ◽

Vol 160 (3) ◽

pp. 486-494 ◽

Cited By ~ 47

Author(s):

Masao Kamimura ◽

Jong Oh Kim ◽

Alexander V. Kabanov ◽

Tatiana K. Bronich ◽

Yukio Nagasaki

Keyword(s):

Drug Delivery ◽

Drug Delivery System ◽

Delivery System ◽

Cationic Surfactants ◽

Ph Responsive ◽

Block Ionomer Complexes ◽

Block Ionomer

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Surface-Modified Nanoparticles to Improve Drug Delivery

Dekker Encyclopedia of Nanoscience and Nanotechnology, Third Edition ◽

10.1081/e-enn3-120051984 ◽

2014 ◽

pp. 1-7

Author(s):

Felipe Oyarzun-Ampuero ◽

Marcelo J. Kogan ◽

Andrónico Neira-Carrillo ◽

Javier O. Morales

Keyword(s):

Drug Delivery ◽

Surface Modified ◽

Surface Modified Nanoparticles ◽

Improve Drug Delivery

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Brain-Targeted Drug Delivery with Surface-Modified Nanoparticles

Surface Modification of Nanoparticles for Targeted Drug Delivery ◽

10.1007/978-3-030-06115-9_15 ◽

2019 ◽

pp. 277-310 ◽

Cited By ~ 1

Author(s):

Sunita Lahkar ◽

Malay K. Das

Keyword(s):

Drug Delivery ◽

Targeted Drug Delivery ◽

Targeted Drug ◽

Surface Modified ◽

Surface Modified Nanoparticles

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A comprehensive review on polymeric micelles: a promising drug delivery carrier

Journal of Analytical & Pharmaceutical Research ◽

10.15406/japlr.2021.10.00372 ◽

2021 ◽

Vol 10 (3) ◽

pp. 102-107

Author(s):

Ajay Kumar

Keyword(s):

Drug Delivery ◽

Drug Release ◽

Drug Delivery Systems ◽

Polymeric Micelles ◽

Delivery Systems ◽

Hydrophobic Drug ◽

Drug Release Profile ◽

Physiological Conditions ◽

Drug Molecules ◽

Drug Delivery Carrier

The main aim of drug delivery systems is to regulate the rate of drug release as per the patient's physiological conditions as well as the progression of the illness or as per the circadian rhythms. To achieve such objectives, the new drug delivery systems have been developed to provide the drug release profile, which is based on each patient's needs. Different researches have been done to create drug delivery carriers, focusing on targeting and delivering hydrophobic drug molecules. This review focuses on Polymeric Micelles as the promising drug delivery carrier due to its high stability, protective property against the harsh gastrointestinal environment.

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Surface modified polymeric nanoparticles for drug delivery: preparation and applications

Recent Patents on Drug Delivery & Formulation ◽

10.2174/1872211314666200904105036 ◽

2020 ◽

Vol 14 ◽

Author(s):

Garima Joshi ◽

Krutika Sawant ◽

Mitali Patel ◽

Deepak Chaudhary

Keyword(s):

Drug Delivery ◽

Targeted Delivery ◽

Surface Engineering ◽

Polymeric Nanoparticles ◽

Biochemical Properties ◽

Site Of Action ◽

Hiv Drugs ◽

Surface Modified ◽

Surface Modified Nanoparticles ◽

Anti Hiv

: Nanotechnology is one of the emerging fields in the drug delivery for targeting the drug to the site of action. The polymeric nanoparticles as drug delivery systems have gained importance for the last few decades. They offer advantages over liposomes, dendrimers, emulsions etc. Surface engineering of polymeric nanoparticles is widely utilized to effectively target the cells in various diseases such as cancer, HIV infection. Surface modified nanoparticles offer various advantages such as targeted drug delivery, reduction in side effects, dose reductionand improved therapeutic efficacy. Moreover, they can aid in improving physical and biochemical properties, pharmacokinetic and pharmacodynamic profiles of drug. Surface modified polymeric nanoparticles can provide targeted delivery of drugs into specific cells, especially when targets are intracellular localized. This approach would be more advantageous for the delivery of various anticancer, anti inflammatory, anti HIV drugs for more effective therapy. This review focuses on the techniques used for fabrication of polymeric nanoparticles, material used for surface modification and their applications.

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