A Review on Anti-Cancer Activity of Some of the Oil-Soluble Organosulphur Compounds Against Colon Cancer

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Apeksha Saraf ◽  
Nidhi Dubey
Oncotarget ◽  
2017 ◽  
Vol 8 (50) ◽  
pp. 87379-87389 ◽  
Author(s):  
Mancang Gu ◽  
Reiko Nishihara ◽  
Yang Chen ◽  
Wanwan Li ◽  
Yan Shi ◽  
...  

2018 ◽  
Vol 9 (9) ◽  
Author(s):  
Su Jin Kim ◽  
Tae Hwan Noh ◽  
Sujin Son ◽  
Do Hyun Kim ◽  
Wooseong Kim ◽  
...  

2021 ◽  
Vol 43 (2) ◽  
pp. 244-244
Author(s):  
Urooj Nazim Urooj Nazim ◽  
Silpa Narayanan Silpa Narayanan ◽  
Mohsin Ali Mohsin Ali ◽  
Khalid Mohammed Khan Khalid Mohammed Khan ◽  
Basharat Ali Basharat Ali ◽  
...  

In the present study, a series of twelve thiazolyl hydrazone derivatives of 1-indanone was synthesized and characterized by various spectroscopic techniques such as UV-Visible, NMR, IR and Mass Spectrometry. All the synthesized target compounds were subjected to MTT assay for cytotoxicity screening and evaluation of their anti-cancer activity on various cell lines of human cancer including glioblastoma (SNB-19), prostate cancer (PC-3), Lung cancer (NCI-H460), human ovarian carcinoma (SK-OV-3 and IGROV-1), human leukemia (K-562) and human colon cancer(HCT116).Three synthesized compounds showed promising anti-cancer activity against the colon cancer cell HCT 116 cells with IC50 ranging from 1.25and#177;0.02 to 5.04and#177;0.2 and#181;M. On the other hand all the compounds didn’t show cytotoxic activity against other forms of human cancer cells.


Author(s):  
Ramachandran K ◽  
Venketnarayanan R ◽  
Rajesh Yadav ◽  
Suresh R ◽  
Sumitra Devkota

Colorectal cancer is the second leading cause of cancer death in the United States for both men and women. The rate of colon cancer incidence was low in India but is presently increasing; out of 3.5 million cancer cases, 35,000 have colon cancer. Polyps which are the small growths in the colon are most often benign, even though some have the potentiality to become cancerous. Up to two-thirds of the colorectal polyps are pre-malignant and they are linked with a risk of colorectal cancer. About 60% of currently used anti-cancer agents are derived from a natural source (i.e. plants). In our study anti-cancer potential of the extract of Coldenia procumbens was studied and the synthesis of the anti-cancer moiety has been done. With the findings, it can be concluded that the plant Coldenia procumbens Linn and possess anti colorectal cancer activity. Before the clinical usage of extract, through toxicological profile has to be determined on the crude extracts as well as on isolated compounds to confirm the safety of the drug.


2020 ◽  
Author(s):  
Brian D. Kelly ◽  
Victoria McLeod ◽  
Rachael Walker ◽  
Jeannette Schreuders ◽  
Susan Jackson ◽  
...  

2018 ◽  
Vol 12 (6) ◽  
pp. 727-732 ◽  
Author(s):  
Pragyan Paramita ◽  
Vimala Devi Subramaniam ◽  
Ramachandran Murugesan ◽  
Madhumala Gopinath ◽  
Ilangovan Ramachandran ◽  
...  

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