In Vitro Activity of Selected Medicinal Plant Extracts Against Mycobacterium tuberculosis and other Non Mycobacterial Pathogens

2020 ◽  
Vol 13 (1) ◽  
pp. 113-118
Author(s):  
Vaishnavi Chandramouli
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Medicinal Plant ◽  
Plant Extracts ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Medicinal Plant Extracts

scholarly journals In Vitro Activity of Copper(II) Complexes, Loaded or Unloaded into a Nanostructured Lipid System, against Mycobacterium tuberculosis

2016 ◽  
Vol 17 (5) ◽  
pp. 745 ◽  
Author(s):  
Patricia Silva ◽  
Paula Souza ◽  
Giovana Calixto ◽  
Erica Lopes ◽  
Regina Frem ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Lipid System

scholarly journals Biological activity from indigenous medicinal plants of Mauritius

2005 ◽  
Vol 77 (1) ◽  
pp. 41-51 ◽  
Author(s):  
A. Gurib-Fakim ◽  
H. Subratty ◽  
F. Narod ◽  
J. Govinden-Soulange ◽  
F. Mahomoodally
Keyword(s):  
Medicinal Plant ◽  
Plant Extracts ◽  
Biological Properties ◽  
Pharmacological Properties ◽  
Plant Materials ◽  
In Vivo Screening ◽  
Medicinal Plant Extracts ◽  
Minor Ailments

The Mauritian population has a long tradition in the use of ethno-medicine, and the practice is still strong, especially in the treatment of minor ailments. Such interest stems from an existing culture, and many “tisanes” are still prepared from plant materials and sold in several markets around the island.This paper will focus on the various chemical/biological screening techniques currently being used to evaluate the biological properties of medicinal plant extracts. Particular emphasis will be put on extraction and various screening for biological/pharmacological properties. Due consideration will be given to the pharmacological approaches that utilize different animal models for the in vitro and in vivo screening of medicinal plant extracts.

377-PA11 In vitro activity of ciprofloxacin against Mycobacterium tuberculosis

1995 ◽  
Vol 76 ◽  
pp. 85 ◽  
Author(s):  
M. Jonchevska ◽  
S. Talevski ◽  
E. Bakalova ◽  
O. Kungulovska
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals Correction: In Vitro Activity of Rifampicin and Verapamil Combination in Multidrug-Resistant Mycobacterium tuberculosis

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0133343 ◽  
Author(s):  
Fernanda de Oliveira Demitto ◽  
Renata Claro Ribeiro do Amaral ◽  
Flaviane Granero Maltempe ◽  
Vera Lúcia Dias Siqueira ◽  
Regiane Bertin de Lima Scodro ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Multidrug Resistant ◽  
Vitro Activity ◽  
In Vitro Activity

scholarly journals Activity of Medicinal Plant Extracts on Multiplication ofMycobacterium tuberculosisunder Reduced Oxygen Conditions Using Intracellular and Axenic Assays

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Purva D. Bhatter ◽  
Pooja D. Gupta ◽  
Tannaz J. Birdi
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Medicinal Plant ◽  
Plant Extracts ◽  
Bactericidal Activity ◽  
Piper Nigrum ◽  
Ocimum Sanctum ◽  
Acorus Calamus ◽  
Anaerobic Conditions ◽  
Bacterial Killing ◽  
Medicinal Plant Extracts

Aim.Test the activity of selected medicinal plant extracts on multiplication ofMycobacterium tuberculosisunder reduced oxygen concentration which represents nonreplicating conditions.Material and Methods.Acetone, ethanol and aqueous extracts of the plantsAcorus calamusL. (rhizome),Ocimum sanctumL. (leaf),Piper nigrumL. (seed), andPueraria tuberosaDC. (tuber) were tested onMycobacterium tuberculosisH37Rv intracellularly using an epithelial cell (A549) infection model. The extracts found to be active intracellularly were further studied axenically under reducing oxygen concentrations.Results and Conclusions.Intracellular multiplication was inhibited ≥60% by five of the twelve extracts. Amongst these 5 extracts, in axenic culture,P. nigrum(acetone) was active under aerobic, microaerophilic, and anaerobic conditions indicating presence of multiple components acting at different levels andP. tuberosa(aqueous) showed bactericidal activity under microaerophilic and anaerobic conditions implying the influence of anaerobiosis on its efficacy.P. nigrum(aqueous) andA. calamus(aqueous and ethanol) extracts were not active under axenic conditions but only inhibited intracellular growth ofMycobacterium tuberculosis, suggesting activation of host defense mechanisms to mediate bacterial killing rather than direct bactericidal activity.

scholarly journals In vitro susceptibility of Helicobacter pylori to protolichesterinic acid from the lichen Cetraria islandica.

1997 ◽  
Vol 41 (1) ◽  
pp. 215-217 ◽  
Author(s):  
K Ingolfsdottir ◽  
M A Hjalmarsdottir ◽  
A Sigurdsson ◽  
G A Gudjonsdottir ◽  
A Brynjolfsdottir ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Helicobacter Pylori ◽  
Plant Extracts ◽  
Active Component ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Salt Form ◽  
Traditional Use ◽  
In Vitro Susceptibility

With reference to the traditional use of Cetraria islandica (Iceland moss) for relief of gastric and duodenal ulcer, plant extracts were screened for in vitro activity against Helicobacter pylori. (+)-Protolichesterinic acid, an aliphatic alpha-methylene-gamma-lactone, was identified as an active component. The MIC range of protolichesterinic acid, in free as well as salt form, was 16 to 64 micrograms/ml.

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