scholarly journals FACTORS OF INFLUENCE ON PAIN INTENSITY AND FUNCTIONAL ACTIVITY OF PATIENTS WITH BACK PAIN OF DIFFERENT LOCALIZATION

2019 ◽  
pp. 35-43
Author(s):  
I. G. Maslova ◽  
N. O. Mykhailovska ◽  
T. M. Slobodin
Keyword(s):  
Mental Health ◽  
Chronic Pain ◽  
Back Pain ◽  
Pain Syndrome ◽  
Anxiety And Depression ◽  
Vital Activity ◽  
Lower Back ◽  
Sf 36 ◽  
Factors Of Influence ◽  
High Level

In order to identify the probable factors of the effect on the intensity of the pain syndrome and the parameters of the functioning of patients with back pain, depending on the location of the pain syndrome and concomitant pathology, 139 patients with non-specific back pain who were in inpatient treatment in the medical and sanitary part of JSC "Motor -Sich "with the first detected acute pain syndrome and acute exacerbation of chronic. The results of the study revealed a decrease in the level of physical functioning, deterioration of vital activity and the state of general and mental health (on the scale of SF-36) in patients with exacerbation of chronic pain, the lowest indicators of vital activity, social functioning, mental health and a high level of anxiety and depression - in patients with cervical and cranial localization of pain syndrome, despite the fact that patients with localized pain in the lower back are markedly higher levels of pain not only for YES, but also zg BP bottom axis scale SF-36. Patients with a combination of arterial hypertension and diabetes have been shown to have chronic pain syndrome.

scholarly journals FACTORS OF INFLUENCE ON PAIN INTENSITY AND FUNCTIONAL ACTIVITY OF PATIENTS WITH BACK PAIN OF DIFFERENT LOCALIZATION

2019 ◽  
pp. 35-43
Author(s):  
I. G. Maslova ◽  
N. O. Mykhailovska ◽  
T. M. Slobodin
Keyword(s):  
Mental Health ◽  
Chronic Pain ◽  
Back Pain ◽  
Pain Syndrome ◽  
Anxiety And Depression ◽  
Vital Activity ◽  
Lower Back ◽  
Sf 36 ◽  
Factors Of Influence ◽  
High Level

In order to identify the probable factors of the effect on the intensity of the pain syndrome and the parameters of the functioning of patients with back pain, depending on the location of the pain syndrome and concomitant pathology, 139 patients with non-specific back pain who were in inpatient treatment in the medical and sanitary part of JSC "Motor -Sich "with the first detected acute pain syndrome and acute exacerbation of chronic. The results of the study revealed a decrease in the level of physical functioning, deterioration of vital activity and the state of general and mental health (on the scale of SF-36) in patients with exacerbation of chronic pain, the lowest indicators of vital activity, social functioning, mental health and a high level of anxiety and depression - in patients with cervical and cranial localization of pain syndrome, despite the fact that patients with localized pain in the lower back are markedly higher levels of pain not only for YES, but also zg BP bottom axis scale SF-36. Patients with a combination of arterial hypertension and diabetes have been shown to have chronic pain syndrome.

scholarly journals Brain-Derived Neurotrophic Factor and Immune Cells in Osteoarthritis, Chronic Low Back Pain, and Chronic Widespread Pain Patients: Association with Anxiety and Depression

Medicina ◽  
2021 ◽  
Vol 57 (4) ◽  
pp. 327
Author(s):  
Dominique Josephine Dimmek ◽  
Christoph Korallus ◽  
Sabine Buyny ◽  
Gutenbrunner Christoph ◽  
Ralf Lichtinghagen ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Low Back Pain ◽  
Back Pain ◽  
Immune Cells ◽  
Chronic Widespread Pain ◽  
Anxiety And Depression ◽  
Low Back ◽  
Widespread Pain ◽  
Chronic Pain Patients ◽  
Pain Patients

Background and Objectives: Musculoskeletal dysfunction can induce several types of chronic pain syndromes. It is of particular interest to elucidate the pathomechanism of different forms of chronic pain. It is possible that patients who have developed chronic widespread pain (CWP) may endure different pathomechanisms as compared to those who suffer from local pain (osteoarthritis, OA) and regional pain (chronic low back pain, cLBP), especially with regard to pain regulation and its related biomediators. The aim of this study was to determine the differences in pathomechanisms among these patients by measuring pain-related biomediators, particularly brain-derived neurotrophic factor (BDNF). Additionally, subpopulations of immune cells were determined in parallel. Materials and Methods: Patients and healthy subjects (HSs) were recruited (age and gender-matched). BDNF was measured from serum samples of patients and HSs and the data of body composition parameters were recorded. Additionally, both patients and HSs were asked to fill in questionnaires related to pain intensity, anxiety, and depression. Results: Our results highlight that the levels of both free and total BDNF are significantly lower in pain patients compared to HSs, with p values of 0.041 and 0.024, respectively. The number of CD3− CD56bright natural killer (NK) cells shows significant differences between the groups. Comparing all chronic pain patients with HSs reveals a significantly lower number of CD4+ CD8+ T cells (p = 0.031), CD3− CD56bright NK cells (p = 0.049) and CD20+ CD3− cells (p = 0.007). Conclusions: To conclude, it seems that a general conformity between the pathomechanisms of different chronic pain diseases exists, although there are unique findings only in specific chronic pain patients.

scholarly journals Emotional and Neurobehavioural Status in Chronic Pain Patients

2011 ◽  
Vol 16 (1) ◽  
pp. 41-43 ◽  
Author(s):  
He Shuchang ◽  
He Mingwei ◽  
Jia Hongxiao ◽  
Wu Si ◽  
Yang Xing ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Back Pain ◽  
Lower Back Pain ◽  
Mood State ◽  
Control Group ◽  
Chronic Lower Back Pain ◽  
Control Subjects ◽  
Lower Back ◽  
Chronic Pain Patients ◽  
Pain Patients

OBJECTIVE: To investigate the emotional and neurobehavioural status of patients suffering from chronic pain.METHODS: Fifteen male patients with chronic lower back pain and 15 healthy control subjects were studied for approximately six months. Pain was measured using a visual analogue scale. The WHO Neurobehavioral Core Test Battery (NCTB) was used to assess neurobehavioural effects of environmental and occupational exposures.RESULTS: Visual analogue scale results demonstrated a modest range of reported pain (mean [± SD] 62.0±10.8) in chronic pain patients, whereas control subjects reported no measurable pain. With the NCTB, it was found that scores of negative mood state, including anger-hostility, depression-dejection, fatigue-inertia and tension-anxiety in pain patients were significantly higher than scores in the control subjects. By contrast, scores of positive mood state (vigour-activity) in chronic pain patients were lower than those in the control group. The NCTB scores of the Santa Ana Dexterity and Pursuit Aiming II tests in chronic lower back pain patients were lower than those of the control group. Scores for other NCTB sub-tests, including the Digit Span, Benton Visual Retention and Digit Symbol tests, were not significantly different compared with controls.CONCLUSIONS: Chronic lower back pain patients had more negative mood and less positive mood than controls. These patients also demonstrated neuromotor deficits in coordination and reaction time. Further studies are required to examine possible neurological mechanisms and research potential intervention strategies for patients suffering from chronic pain.

Chronic Benign Pain

CNS Spectrums ◽  
1999 ◽  
Vol 4 (9) ◽  
pp. 24-31
Author(s):  
David A. Klein ◽  
Daniel P. Greenfield
Keyword(s):  
Back Pain ◽  
Sickle Cell Disease ◽  
Lower Back Pain ◽  
Reflex Sympathetic Dystrophy ◽  
Pain Syndrome ◽  
Peripheral Neuropathies ◽  
Cell Disease ◽  
Lower Back ◽  
Reflex Sympathetic Dystrophy Syndrome ◽  
Metastatic Process

AbstractChronic benign pain (CBP) can be defined as a type of unpleasant sensory experience that arises from inflammation, visceral stress or damage, or other such pathophysiologic process(es), and that is not associated with a metastatic process. A patient's complaint of pain should be taken seriously by the practitioner, both in terms of the discomfort evoked and the likelihood that the potential cause of the pain requires diagnostic evaluation. This article reviews the diagnosis and treatment of the following common conditions associated with CBP syndromes: fibromyalgia, lower back pain syndrome, sickle-cell disease, reflex sympathetic dystrophy syndrome, and peripheral neuropathies.

scholarly journals Complex Regional Pain Syndrome and Failed Back Surgery Syndrome With Failed High-Frequency Spinal Cord Stimulation Salvaged With Arthrodesis Revision Surgery and Burst Therapy

Neurosurgery ◽  
2019 ◽  
Vol 66 (Supplement_1) ◽  
Author(s):  
Erin McCormack ◽  
Mansour H Mathkour ◽  
Lora Wallis Kahn ◽  
Maged Guirguis ◽  
Gassan Chaiban ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Back Pain ◽  
Pain Relief ◽  
High Frequency ◽  
Pain Syndrome ◽  
Failed Back Surgery Syndrome ◽  
Foot Pain ◽  
Failed Back Surgery ◽  
Back Surgery

Abstract INTRODUCTION Complex regional pain syndrome (CRPS) is a disabling form of constant and intense chronic pain involving a limb. Failed back surgery syndrome (FBSS) is chronic back pain following back surgery. Burst stimulation is a novel concept applied recently to treat chronic pain through spinal cord stimulation (SCS). The impulses are thought to travel to the thalamus to treat sensory, affective, and attentional components of neuropathic pain by targeting both the somatosensory cortex and the limbic system. METHODS A 50-yr-old female presented 1 yr after L5-S1 posterior instrumentation and posterolateral arthrodesis for spondylolisthesis with disabling Type I CRPS of her left foot and back pain. Postoperative improvement in back pain was noted but her left leg pain became worse despite SCS reprogramming. Two months later, she underwent placement of a different paddle lead at T12 and a new pulse generator using burst therapy. This resulted in complete resolution of foot pain. She remains pain-free 5 mo postoperatively. RESULTS Our patient underwent a T9-T10 high frequency (10 kHz) SCS trial followed by permanent paddle lead placement at T9-10 which provided more than 50% foot pain relief resulting in improved range of motion. However, worsening back pain and pseudoarthrosis mandated a revision of her prior arthrodesis 6 mo after SCS surgery. CONCLUSION In selected patients with FBSS and CRPS, revision of arthrodesis combined with SCS may be needed to achieve adequate pain relief. Burst therapy may be superior to high frequency stimulation in select patients.

scholarly journals Comprehensive Review of Epidemiology, Scope, and Impact of Spinal Pain

2009 ◽  
Vol 4;12 (4;7) ◽  
pp. E35-E70
Author(s):  
Laxmaiah Manchikanti
Keyword(s):  
Health Care ◽  
Chronic Pain ◽  
Low Back Pain ◽  
Back Pain ◽  
Neck Pain ◽  
Pain Syndrome ◽  
Spinal Pain ◽  
The United States ◽  
Low Back ◽  
Chronic Pain Syndrome

Persistent pain interfering with daily activities is common. Chronic pain has been defined in many ways. Chronic pain syndrome is a separate entity from chronic pain. Chronic pain is defined as, “pain that persists 6 months after an injury and beyond the usual course of an acute disease or a reasonable time for a comparable injury to heal, that is associated with chronic pathologic processes that cause continuous or intermittent pain for months or years, that may continue in the presence or absence of demonstrable pathologies; may not be amenable to routine pain control methods; and healing may never occur.” In contrast, chronic pain syndrome has been defined as a complex condition with physical, psychological, emotional, and social components. The prevalence of chronic pain in the adult population ranges from 2% to 40%, with a median point prevalence of 15%. Among chronic pain disorders, pain arising from various structures of the spine constitutes the majority of the problems. The lifetime prevalence of spinal pain has been reported as 54% to 80%. Studies of the prevalence of low back pain and neck pain and its impact in general have shown 23% of patients reporting Grade II to IV low back pain (high pain intensity with disability) versus 15% with neck pain. Further, age related prevalence of persistent pain appears to be much more common in the elderly associated with functional limitations and difficulty in performing daily life activities. Chronic persistent low back and neck pain is seen in 25% to 60% of patients, one-year or longer after the initial episode. Spinal pain is associated with significant economic, societal, and health impact. Estimates and patterns of productivity losses and direct health care expenditures among individuals with back and neck pain in the United States continue to escalate. Recent studies have shown significant increases in the prevalence of various pain problems including low back pain. Frequent use of opioids in managing chronic non-cancer pain has been a major issue for health care in the United States placing a significant strain on the economy with the majority of patients receiving opioids for chronic pain necessitating an increased production of opioids, and escalating costs of opioid use, even with normal intake. The additional costs of misuse, abuse, and addiction are enormous. Comorbidities including psychological and physical conditions and numerous other risk factors are common in spinal pain and add significant complexities to the interventionalist’s clinical task. This section of the American Society of Interventional Pain Physicians (ASIPP)/EvidenceBased Medicine (EBM) guidelines evaluates the epidemiology, scope, and impact of spinal pain and its relevance to health care interventions. Key words: Chronic pain, chronic spinal pain, chronic low back pain, chronic neck pain, chronic thoracic pain, prevalence, health care utilization, loss of productivity, interventional techniques, surgery, comorbid factors, socioeconomic effects, health care impact

scholarly journals Back pain, mental health and substance use are associated in adolescents

2018 ◽  
Author(s):  
SJ Kamper ◽  
ZA Michaleff ◽  
P Campbell ◽  
KM Dunn ◽  
TP Yamato ◽  
...  
Keyword(s):  
Mental Health ◽  
Risk Factors ◽  
Back Pain ◽  
Health Risk ◽  
General Health ◽  
Poor Mental Health ◽  
Anxiety And Depression ◽  
Health Risk Factors ◽  
The Past ◽  
Pain Frequency

AbstractBackgroundDuring adolescence, prevalence of pain and health risk factors such as smoking, alcohol use, and poor mental health rise sharply. While these risk factors and mental health are accepted public health concerns, the same is not true for pain. The aim of this study was to describe the relationship between back pain and health risk factors in adolescents.MethodsCross-sectional data from the Healthy Schools Healthy Futures study, and the Australian Child Wellbeing Project was used. The mean age of participants was 14-15 years. Children were stratified according to the frequency they experienced back pain over the past 6 months. Within each strata, the proportion of children that reported drinking alcohol or smoking in the past month and the proportion that experienced feelings of anxiety or depression was reported. Test-for-trend analyses assessed whether increasing frequency of pain was associated with health risk factors.ResultsData from approximately 2,500 and 3,900 children in the two studies was analysed. Larger proportions of children smoked or drank alcohol within each strata of increasing pain frequency. The trend with report of anxiety and depression was less clear, although there was a marked difference between the children that reported pain ‘rarely or never’, and those that experienced back pain more frequently.ConclusionTwo large, independent samples show Australian adolescents that experience back pain more frequently are also more likely to smoke, drink alcohol and report feelings of anxiety and depression. Pain appears to be part of the picture of general health risk in adolescents.What is already known on this subject?The prevalence of back pain rises steeply during the adolescent years, and is responsible for considerable personal impact in a substantial minority. During this time, indicators of adverse health risk such as smoking, alcohol use, anxiety and depression also increase in prevalence. Pain and lifestyle-related health risk factors can have ongoing consequences that stretch into adulthood.What this study adds?This study shows a close relationship between increasing pain frequency, and tendency to engage in health risk behaviours and experience indicators of poor mental health in adolescents. This study shows that pain may be an important consideration in understanding the general health, and health risk in adolescents.

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