scholarly journals THE STATE OF CHANGES IN THE BIOELECTRICAL ACTIVITY OF THE BRAIN IN PATIENTS UNDERGOING SURGERY USING GENERAL ANESTHESIA WITH STANDART MANAGEMENT OF THE POSTOPERATIVE PERIOD

2019 ◽  
pp. 95-101
Author(s):  
O. L. Tovazhyanskaya ◽  
S. S. Dubivska ◽  
Yu. B. Grigorov ◽  
E. T. Solovyova
Keyword(s):  
General Anesthesia ◽  
Functional State ◽  
Postoperative Period ◽  
Surgical Stress ◽  
Bioelectrical Activity ◽  
Emergency Medical Care ◽  
Standard Management ◽  
Number Of Patients ◽  
Two Stages ◽  
The Brain

The purpose of this work is to determine the functional state of the brain of patients on the basis of the electroencephalogram, which were operated under general anesthesia against the background of the standard management of the postoperative period. The study was conducted in the surgical departments of various profiles on the basis of the Kharkov City Clinical Hospital of Emergency and Emergency Medical Care. prof. A.I. Meshchaninov. The study was conducted with the total number of patients in 86 young, middle-aged and elderly patients with surgical pathology who underwent surgery under general anesthesia. The study of the functional state of the brain by determining the bioelectrical activity of the brain, by conducting an electroencephalogram, was determined in two stages: before surgery and 3-5 days after surgery with general anesthesia. Based on the data obtained, it is possible to recommend an electroencephalogram to assess the functional state of the brain of patients undergoing surgery under general anesthesia. Marked electroencephalographic changes in the period after the operation indicate a deterioration in the functional state of the brain, which are a consequence of the effects of anesthesia, surgical stress, and effects on cognitive function.

scholarly journals THE STATE OF CHANGES IN THE BIOELECTRICAL ACTIVITY OF THE BRAIN IN PATIENTS UNDERGOING SURGERY USING GENERAL ANESTHESIA WITH STANDART MANAGEMENT OF THE POSTOPERATIVE PERIOD

2019 ◽  
pp. 95-101
Author(s):  
O. L. Tovazhyanskaya ◽  
S. S. Dubivska ◽  
Yu. B. Grigorov ◽  
E. T. Solovyova
Keyword(s):  
General Anesthesia ◽  
Functional State ◽  
Postoperative Period ◽  
Surgical Stress ◽  
Bioelectrical Activity ◽  
Emergency Medical Care ◽  
Standard Management ◽  
Number Of Patients ◽  
Two Stages ◽  
The Brain

The purpose of this work is to determine the functional state of the brain of patients on the basis of the electroencephalogram, which were operated under general anesthesia against the background of the standard management of the postoperative period. The study was conducted in the surgical departments of various profiles on the basis of the Kharkov City Clinical Hospital of Emergency and Emergency Medical Care. prof. A.I. Meshchaninov. The study was conducted with the total number of patients in 86 young, middle-aged and elderly patients with surgical pathology who underwent surgery under general anesthesia. The study of the functional state of the brain by determining the bioelectrical activity of the brain, by conducting an electroencephalogram, was determined in two stages: before surgery and 3-5 days after surgery with general anesthesia. Based on the data obtained, it is possible to recommend an electroencephalogram to assess the functional state of the brain of patients undergoing surgery under general anesthesia. Marked electroencephalographic changes in the period after the operation indicate a deterioration in the functional state of the brain, which are a consequence of the effects of anesthesia, surgical stress, and effects on cognitive function.

scholarly journals ДИНАМИКА ИЗМЕНЕНИЙ БИОЭЛЕКТРИЧЕСКОЙ АКТИВНОСТИ ГОЛОВНОГО МОЗГА У ПАЦИЕНТОВ, КОТОРЫМ ПРОВОДИТСЯ ХИРУРГИЧЕСКОЕ ВМЕШАТЕЛЬСТВО С ИСПОЛЬЗОВАНИЕМ ОБЩЕЙ АНЕСТЕЗИИ

World Science ◽  
2019 ◽  
Vol 2 (2(42)) ◽  
pp. 15-18
Author(s):  
Дубовская С. С. ◽  
Товажнянская Е. Л. ◽  
Григоров Ю. Б. ◽  
Соловйова Е. Т. ◽  
Долженко М. А.
Keyword(s):  
Comparative Analysis ◽  
General Anesthesia ◽  
Functional State ◽  
Postoperative Period ◽  
Bioelectrical Activity ◽  
Emergency Medical Care ◽  
Bioelectric Activity ◽  
Regulatory Changes ◽  
Two Stages ◽  
The Brain

The purpose of this work is to determine the functional state of the brain of patients on the basis of the EEG, who underwent surgery under general anesthesia.The study was conducted in the surgical departments of various profiles on the basis of the Kharkov City Clinical Hospital of Emergency and Emergency Medical Care. prof. A. I. Meshchaninov.The study of the functional state of the brain by determining the bioelectrical activity of the brain, by conducting an EEG, was determined in two stages: before surgery and 3-5 days after surgery with general anesthesia.In a comparative analysis of the results obtained, a strong direct correlation is determined between the degree of regulatory changes in the bioelectric activity of the brain in the postoperative period and the age of the patients. Also, in a comparative analysis of the results, a strong direct correlation is determined between the degree of regulatory changes in the bioelectric activity of the brain in the postoperative period and the duration of anesthesia support. Given the above, we can recommend an EEG to assess the functional state of the brain of patients undergoing surgery under general anesthesia.

scholarly journals Functional state of the brain bioelectric activity in treatment of diaphyseal lesions of the radius using the transosseous osteosynthesis of the wire and rod arrangement

2021 ◽  
Vol 6 (4) ◽  
pp. 213-219
Author(s):  
I. N. Kinash ◽  
M. E. Puseva ◽  
Ch. Z. Butaev ◽  
T. K. Verkhozina ◽  
E. G. Ippolitova
Keyword(s):  
External Fixation ◽  
Functional State ◽  
Postoperative Period ◽  
Bioelectrical Activity ◽  
Bioelectric Activity ◽  
Zonal Distribution ◽  
The Central Nervous System ◽  
The Stability ◽  
High Degree ◽  
The Brain

Radial fracture is the most common trauma to the musculoskeletal system and accounts for 50 % of traumatic injuries to the bones of the upper limb. Disability in patients with fractures of the forearm bones ranges from 6 to 8 months, so the choice of the most effective method of treatment is very relevant. Currently, an important point is the tendency of optimizing the transosseous method by eliminating the disadvantages and looking for new advantages of external fixation. Bone fracture and associated surgical intervention are always accompanied by varying degrees of changes in the links of the central nervous system, hemodynamics and metabolism. In order to study the bioelectrical activity of the brain in 47 patients with a fracture of the radial diaphysis treated in the Traumatology Department of the Irkutsk Scientific Centre of Surgery and Traumatology, in the pre- and postoperative period we compared EEG indicators of two variants of the layout of the external fixation apparatus (EF): wire and rod. Analysis of the rhythms of bioelectrical activity of the brain in both groups in the preoperative period revealed a normal zonal distribution with the dominance of the alpha rhythm on the EEG, which generally reflects a rather high degree of organization of neuroactivity and indicates the stability of cerebral homeostasis. At the same time, in the group of patients with a wire-mounted EF device in the postoperative period, EEG indices significantly differed from the values of the norm and ndicators in the group with a rod-shaped arrangement. A decrease in the amplitude of alpha and beta rhythms was noted, as well as a shift in the frequency of bioelectric activity towards slow waves, which is a sign characteristic of discirculatory encephalopathy. An EEG study using the method of transosseous osteosynthesis with EF devise of a rod assembly showed its greater efficiency compared to the use of an EF device of a wire assembly during treatment and rehabilitation. Thus, the study of the bioelectric activity of the brain is a reliable method for assessing its functional state after an injury, as well as the effectiveness of the treatment.

scholarly journals Functional State of the Bioelectrical Activity of the Brain in Cervical Osteochondrosis

2019 ◽  
Vol 4 (6) ◽  
pp. 7-12 ◽  
Author(s):  
I. N. Kinash ◽  
T. K. Verkhozina ◽  
E. G. Ippolitova ◽  
O. V. Sklyarenko ◽  
Z. V. Koshkareva
Keyword(s):  
Functional State ◽  
Bioelectrical Activity ◽  
The Brain

PREOPERATIVE DIAGNOSIS OF THE FUNCTIONAL STATE OF THE SPHINCTER COMPLEX IN THE TREATMENT OF RECTAL FISTULAS

2021 ◽  
pp. 31-35
Author(s):  
T. M. Firsyk ◽  
I. A. Kryvoruchko ◽  
O. P. Bozhko
Keyword(s):  
Anal Sphincter ◽  
Functional State ◽  
Postoperative Period ◽  
Contractile Function ◽  
Normative Values ◽  
Bioelectrical Activity ◽  
Surgical Department ◽  
Sphincter Complex ◽  
Standard Values ◽  
Sphincter Insufficiency

Abstract. Introduction. Preoperative determination of the functional state of the sphincter apparatus of the rectum is an important part of the treatment of patients. Assessment and analysis of the functional viability of the anal sphincter are necessary for the choice of tactics for surgical correction of rectal fistulas. This approach makes it possible to assess the effectiveness of a specific surgical method and determine the degree of sphincter insufficiency in the postoperative period. The aim of the study: to assess the normative values of neurophysiologicsl parameters of the sphincter apparatus of the rectum and pelvic floor muscles by using the method of electrosphincteromyography. Materials and methods. The study included 93 patients who were treated in the surgical department of the Kharkiv Regional Hospital for rectal fistulas. Indicators of the contractile function of the sphincter apparatus were determined by the method of interference electrosphincteromyography in the preoperative period. The comparison group consisted of 28 volunteers who did not have rectal diseases associated with impaired intestinal retention function (0 points on the Wexner incontinence scale). Results. The standard values of the bioelectrical activity of the sphincter apparatus were obtained by examining a group of volunteers by the method of interference electrosphincteromyography. The analysis of the results obtained demonstrates a slight decrease in the initial indicators of the bioelectric activity of the sphincter complex in the postoperative period. Conclusions. Minimally invasive methods of surgical treatment of rectal fistulas are preferred, because during the study, patients showed a decrease in the initial parameters of the contractile viability of the anal sphincter.

A simple treatment planning strategy for patients with multiple metastases treated with Gamma Knife surgery

2006 ◽  
Vol 105 (Supplement) ◽  
pp. 2-4 ◽  
Author(s):  
James G. Douglas ◽  
Robert Goodkin
Keyword(s):  
Mr Imaging ◽  
Treatment Planning ◽  
Gamma Knife ◽  
Gamma Knife Surgery ◽  
Planning Method ◽  
Cns Metastases ◽  
Cell Lung Carcinoma ◽  
Dose Volume Histograms ◽  
Number Of Patients ◽  
The Brain

ObjectIn a substantial number of patients treated at the authors' facility for brain metastases, additional lesions are identified at the time of Gamma Knife surgery (GKS). These lesions are often widely dispersed and may number over 10, which is the maximal number of matrices that can be currently placed for treatment with Leksell Gamma-Plan 4C. The authors describe a simple planning method for GKS in patients with multiple, widely dispersed central nervous system (CNS) metastases.MethodsTwo patients presented with three to five identified recurrent metastases from non–small cell lung carcinoma and breast carcinoma after having received whole-brain radiotherapy. At the time of treatment with GKS in each patient, spoiled-gradient Gd-enhanced magnetic resonance (MR) imaging revealed substantially more metastases than originally thought, which were widely scattered throughout all regions of the brain. The authors simplified the treatment planning approach by dividing the entire CNS contents into six contiguous, nonoverlapping matrices, which allowed for the planning, calculation, and treatment of all lesions.Two patients were successfully treated with GKS for more than 10 CNS metastases by using this simple planning method. Differing peripheral doses to varied-size lesions were delivered by prescribing to different isodose curves within any given matrix when required. Dose–volume histograms showed brain doses as follows: 10% of the total brain volume received 5 to 6.4 Gy; 25% received 3.8 to 4.8 Gy; 50% received 2.7 to 3.1 Gy; and 75% received 2.2 to 2.5 Gy.Conclusions The delineation of more metastases than appreciated on the diagnostic MR imaging is a common occurrence at the time of GKS at the authors' institution. The treatment of multiple (>10), widely dispersed CNS metastases can be simplified by the placement of multiple, contiguous, non-overlapping matrices, which can be employed to treat lesions in all areas of the brain when separate matrices cannot be utilized.

Possibility that the Onset of Autism Spectrum Disorder is Induced by Failure of the Glutamine-Glutamate Cycle

2020 ◽  
Vol 14 (2) ◽  
pp. 170-174
Author(s):  
Koichi Kawada ◽  
Nobuyuki Kuramoto ◽  
Seisuke Mimori
Keyword(s):  
Autism Spectrum Disorder ◽  
Endoplasmic Reticulum ◽  
Environmental Factors ◽  
Endoplasmic Reticulum Stress ◽  
Synapse Formation ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Neurodevelopmental Disease ◽  
Number Of Patients ◽  
The Brain

: Autism spectrum disorder (ASD) is a neurodevelopmental disease, and the number of patients has increased rapidly in recent years. The causes of ASD involve both genetic and environmental factors, but the details of causation have not yet been fully elucidated. Many reports have investigated genetic factors related to synapse formation, and alcohol and tobacco have been reported as environmental factors. This review focuses on endoplasmic reticulum stress and amino acid cycle abnormalities (particularly glutamine and glutamate) induced by many environmental factors. In the ASD model, since endoplasmic reticulum stress is high in the brain from before birth, it is clear that endoplasmic reticulum stress is involved in the development of ASD. On the other hand, one report states that excessive excitation of neurons is caused by the onset of ASD. The glutamine-glutamate cycle is performed between neurons and glial cells and controls the concentration of glutamate and GABA in the brain. These neurotransmitters are also known to control synapse formation and are important in constructing neural circuits. Theanine is a derivative of glutamine and a natural component of green tea. Theanine inhibits glutamine uptake in the glutamine-glutamate cycle via slc38a1 without affecting glutamate; therefore, we believe that theanine may prevent the onset of ASD by changing the balance of glutamine and glutamate in the brain.

Sign in / Sign up

Export Citation Format

Share Document