Folic acid intake for prevention of birth defects among women of childbearing age in West Virginia

2016 ◽  
Vol 2016 (1) ◽  
Author(s):  
Monira Alwhaibi, PhD ◽  
◽  
Rahul Garg, M Pharm ◽  
Nilanjana Dwibedi, PhD ◽  
◽  
...  
2012 ◽  
Vol 15 (7) ◽  
pp. 1216-1227 ◽  
Author(s):  
Sarah C Tinker ◽  
Mary E Cogswell ◽  
Heather C Hamner ◽  
Robert J Berry

AbstractObjectiveThe USA currently fortifies enriched cereal grain products (ECGP) with folic acid at 140 μg/100 g. In addition, folic acid can be voluntarily added to ready-to-eat cereals (RTEC) up to 400 μg/serving and it is found in many dietary supplements, most often at a dose of 400 μg. We sought to model folic acid intake under various fortification and supplementation scenarios.DesignThe National Health and Nutrition Examination Survey is a population-based cross-sectional survey representative of the non-institutionalized, civilian US population. Information on folic acid intake is collected in two 24 h dietary recalls and survey questions on dietary supplement use, which allows estimation of usual total folic acid intake. We modelled five different levels of folic acid fortification in ECGP, while varying the amounts in RTEC and dietary supplements.SettingUnited States.SubjectsUS adults (n 14 353) aged ≥19 years; non-pregnant women of childbearing age (n 4272).ResultsThe percentage of adults with usual daily folic acid intake above the tolerable upper intake level of 1000 μg was influenced more by the typical amount in supplements, while the median intake was influenced more by the ECGP fortification level. By manipulating the amount in at least two sources, it was possible to shift the distribution such that more women of childbearing age consumed the recommended intake of 400 μg of folic acid without increasing the percentage of adults with intake above the tolerable upper intake level. The results varied among population subgroups.ConclusionsOur results suggest that combined strategies are required to meet population recommendations for folic acid intake.


2018 ◽  
Vol 25 (07) ◽  
pp. 1102-1107
Author(s):  
Aamira Hashmi1 ◽  
Qandeel Tahir ◽  
Muhammad Imran ◽  
Naila Azam ◽  
Rukhsana Roshan ◽  
...  

Objectives: Study objectives were devised to assess perceptions of womenregarding importance of folic acid intake, to evaluate role of healthcare providers in counselingof women for folic acid intake, to find out association between perceptions of women withfolic acid intake practices and with counseling of healthcare providers. Study Design: A crosssectional survey. Setting: Gynecology and Obstetrics Wards and OPDs of Tertiary Care andTeaching Hospitals of District Rawalpindi. Period: July-December 2016. Methodology: Studyparticipants were approached by using convenient sampling technique and sample size was of271 women of reproductive age. attending gynecology and obstetrics wards and OPDs of tertiarycare and teaching hospitals of district Rawalpindi. After obtaining consent from institutionalreview board, an interview-based questionnaire was used as data collection tool. Results:Out of 271 women of childbearing age, 60% perceived the importance of folic acid intake indiet. The highest counseling contribution was from doctors (57.6%) while evaluation of role ofhealthcare providers was done regarding counseling. Those who had perceived importanceof folic acid had a significant better intake (p = 0.03). There was a significant associationbetween role of healthcare providers and perceptions (p = 0.02). Conclusion: Majority ofwomen perceived importance of folic acid intake and doctors were playing a significant role incounseling of women regarding folic acid intake during pregnancy. Folic acid intake practiceswere significantly influenced by women’s own perceptions and role of healthcare providers wasa very important factor to direct perceptions of women.


1997 ◽  
Vol 2 (2) ◽  
pp. 114-119
Author(s):  
DEBORAH J DAVIS

Abstract OBJECTIVE: To review the data supporting the periconceptional use of folic acid for the prevention of neural tube defects and to explore how Canadian physicians can help foster preventive strategies. DATA SOURCES: Articles found through a MEDLINE search, 1990 to 1996, and Cochrane Database of Systematic Reviews 1995. Questionnaire survey of selected group of women of childbearing age (November 1994). Chart review of all children with newly diagnosed neural tube defects admitted to the Children's Hospital of Eastern Ontario, Ottawa, Ontario, between 1989 and 1994. DATA SELECTION: Epidemiological studies and randomized trials of supplemental folic acid for prevention of neural tube defects. Epidemio-logical studies and randomized trials of dietary folic acid. DATA SYNTHESIS: An increased periconceptional folic acid intake can prevent the recurrence of and the first occurrence of neural tube defects. However, consumption of adequate folic acid as natural food folate is relatively ineffective. Furthermore, few women are aware of the need for increased folic acid intake, despite Health Canada recommendations, nor do physicians seem to discuss the prevention of neural tube defects with patients. CONCLUSION: Better physician awareness, public education and supplementation of a staple food with folic acid are necessary to make the preventive strategy against neural tube defects effective.


2013 ◽  
Vol 04 (01) ◽  
pp. 49-55 ◽  
Author(s):  
Murad Al-Holy ◽  
Ala’a Eideh ◽  
Suneetha Epuru ◽  
Dima Abu-Jamous ◽  
Ibrahim Ashankyty

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
V A Postoev ◽  
L I Menshikova ◽  
A A Usynina ◽  
A M Grjibovski ◽  
J O Odland

Abstract Introduction Periconceptional use of folic acid supplementation is an evidence-based measure of birth defects prevention. The study was aimed to assess effect of periconceptual use of folic acid on birth defect prevalence in Arkhangelsk county and to investigate socio-demographic factors, which are associated with adherence to this preventive measure. Methods A registry-based study was conducted with data from the Arkhangelsk County Birth Registry for 2012-2015. The study population included 57084 pregnancies to calculate the proportion of women taking folic acid and 53340 pregnancy outcomes without missing data to analyze related socio-demographic characteristics. Results The proportion of women followed a folic acid supplementation before pregnancy was 1.3% (95% CI: 1.2-1.4), during pregnancy - 55.8% (95%CI: 54.6-56.4). Such women had less risk to deliver a newborn with any birth defects (OR = 0,84, 95%CI: 0,75 - 0,95). Considering birth defects prevalence of 38,6 per 1000 newborns in Arkhangelsk county, number needed to prevent one case of birth defect was 142,9. Based on multivariate analysis, nulliparous married women with higher education, aged 30 or more, had a higher chance to use folic acid before and during pregnancy. The history of spontaneous abortion in the mother's medical history and the first pregnancy were negatively associated with the probability of folic acid intake both before and during pregnancy. Conclusions The compliance to periconceptional intake of folic acid among women in the region was low. A level of compliance was associated with such socio-demographic factors as age, education, marital status, gravidity and parity. The findings have direct applications in improving prenatal care in Arkhangelsk county and establishing targets for prenatal counseling. Key messages A level of compliance to primary prevention of birth defects is associated with such socio-demographic factors as age, education, marital status, gravidity and parity. Prenatal counseling in terms of birth defects prevention should be based on socio-demographic characteristics of pregnant women.


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