Device and non-device-guided slow breathing to reduce blood pressure in hypertensive patients: a systematic review protocol. (Preprint)

2021 ◽  
Author(s):  
Kamila Shelry Gonçalves ◽  
Ana Carolina Queiroz Godoy Daniel ◽  
José Luiz Tatagiba Lamas ◽  
Henrique Ceretta Oliveira ◽  
Renata Cristina De Campos Pereira Silveira ◽  
...  

UNSTRUCTURED Introduction: Physiotherapy can include both device-guided slow breathing and device-guided slow breathing in the treatment of systemic arterial hypertension. Methods: A systematic search of all published randomized controlled trials on the effects of device-guided and non-device-guided slow breathing on hypertensive patients, without language restriction, will be carried out until January 2020 in nine databases: Pubmed / MEDLINE (Medical Literature Analysis and Retrieval System Online), Latin American and Caribbean Health Sciences Literature (LILACS), EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), Physiotherapy Evidence Database (PEDro), Cumulative Index to Nursing and Allied Health Literature ( CINAHL), Scopus, Web of Science, Livivo, as well as a search of clinical trial records databases, CT.GOV (Clinical trials.Gov), and bases for the Open Grey gray literature, Gray Literature Report, ProQuest Central (Citation, Abstract or Indexing and Dissertations and Theses). In all of these databases, potentially eligible studies including completed and ongoing ECAs were researched. The quality assessment of the included studies will be conducted using the Cochrane Risk of Bias Tool for Randomized Trials. The overall quality of the evidence for each outcome will be assessed using the Grading of Recommendations, Development and Evaluation (GRADE) system. Discussion: This systematic review will provide a summary of the current evidence on the effects of both device-guided slow breathing and device-guided slow breathing on blood pressure levels. This information can contribute to decision making by health professionals related to the use of these interventions in hypertensive patients. Following the guidelines, this systematic review protocol was registered with the Prospective International Register of Systematic Reviews (PROSPERO) number CRD42020147554.

2021 ◽  
Author(s):  
Kamila Shelry de Freitas Gonçalves ◽  
Ana Carolina Queiroz Godoy Daniel ◽  
José Luiz Tatagiba Lamas ◽  
Renata Cristina De Campos Pereira Silveira ◽  
Lyne Cloutier ◽  
...  

Abstract IntroductionPhysiotherapy can include both device-guided slow breathing and device-guided slow breathing in the treatment of systemic arterial hypertension. MethodsA systematic search of all published randomized controlled trials on the effects of device-guided and non-device-guided slow breathing on hypertensive patients, without language restriction, will be carried out until January 2020 in nine databases: Pubmed / MEDLINE (Medical Literature Analysis and Retrieval System Online), Latin American and Caribbean Health Sciences Literature (LILACS), EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), Physiotherapy Evidence Database (PEDro), Cumulative Index to Nursing and Allied Health Literature ( CINAHL), Scopus, Web of Science, Livivo, as well as a search of clinical trial records databases, CT.GOV (Clinical trials.Gov), and bases for the Open Grey gray literature, Gray Literature Report, ProQuest Central (Citation, Abstract or Indexing and Dissertations and Theses). In all of these databases, potentially eligible studies including completed and ongoing ECAs were researched. The quality assessment of the included studies will be conducted using the Cochrane Risk of Bias Tool for Randomized Trials. The overall quality of the evidence for each outcome will be assessed using the Grading of Recommendations, Development and Evaluation (GRADE) system. DiscussionThis systematic review will provide a summary of the current evidence on the effects of both device-guided slow breathing and device-guided slow breathing on blood pressure levels. This information can contribute to decision making by health professionals related to the use of these interventions in hypertensive patients. Following the guidelines, this systematic review protocol was registered with the Prospective International Register of Systematic Reviews (PROSPERO) number CRD42020147554.


BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e019066 ◽  
Author(s):  
Yang Ye ◽  
Ling-Yong Xiao ◽  
Yi-Hua Liu ◽  
Jing-Wen Yang ◽  
Chao-Qun Yan ◽  
...  

IntroductionThis systematic review protocol aims to provide the methods used to evaluate the effectiveness and safety of acupuncture therapy for treating vascular dementia.Methods and analysisThe following eight databases will be searched from inception to July 2017: Cochrane Central Register of Controlled Trials, PubMed, MEDLINE, EMBASE, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, VIP Database and Wanfang Database. All randomised controlled trials in English or Chinese related to acupuncture for vascular dementia will be included. Outcomes will include change in cognitive function and activities of daily living. The incidence of adverse events will be assessed for safety evaluation. Study inclusion, data extraction and quality assessment will be performed independently by two reviewers. Assessment of risk of bias and data synthesis will be performed using Review Manager software.Ethics and disseminationEthics approval is not required because individual patient data are not included. The findings of this systematic review will be disseminated through peer-reviewed publication or conference presentations.PROSPERO registration numberCRD42017071820.


BMJ Open ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. e025043 ◽  
Author(s):  
Bey-Marrié Schmidt ◽  
Solange Durão ◽  
Ingrid Toews ◽  
Charlotte M Bavuma ◽  
Joerg J Meerpohl ◽  
...  

IntroductionIt is unclear whether early detection of hypertension, through screening, leads to healthier behaviours and better control of blood pressure levels. There is a need to learn from studies that have assessed the impact of different screening approaches on patient important outcomes. This systematic review protocol outlines the methods that will be used to assess the comparative effectiveness of different screening strategies (mass, targeted or opportunistic) for hypertension to reduce morbidity and mortality associated with hypertension.Methods and analysisWe will primarily search Cochrane Central Register of Controlled Trials, Medline, Embase and Latin American and Caribbean Health Sciences Literature (LILACS). Relevant randomised controlled trials, controlled before and after, interrupted time series and prospective analytic cohort studies regardless of publication date, language and geographic location, will be included. We are interested in clinical, adverse event and health system outcomes. Two reviewers will independently screen titles, abstracts and full-text articles against inclusion criteria; perform data extraction and assess risk of bias in included studies. We will assess the certainty of the overall evidence using the Grading of Recommendations Assessment, Development and Evaluation approach and report findings accordingly.Ethics and disseminationNo ethics approval will be sought, as only secondary studies will be used. Findings will be disseminated through peer-reviewed publication and conference presentations.PROSPERO registration numberCRD42018093046.


BMJ Open ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. e034290 ◽  
Author(s):  
Ning Sun ◽  
Mingsheng Sun ◽  
Zhengjie Li ◽  
Rui-Rui Sun ◽  
Ling Zhao ◽  
...  

IntroductionMigraine is the second-leading cause of years lived with disability worldwide. The high prevalence of migraine-related emotional disorders is often overlooked. Acupuncture is often used to treat both migraine and emotional disorders. This systematic review protocol aims to analyse whether acupuncture is effective for treating emotional disorders in patients with migraine.Methods and analysisNine databases will be searched from inception to may 2019: cochrane central register of controlled trials, medline, embase, allied and complementary medicine database, cinahl, china national knowledge infrastructure, chinese biomedical literature database, vip database and wanfang database. Randomised controlled trials (rcts) of acupuncture therapy for migraine with emotional functioning outcomes, which were reported in chinese or english, will be included. The primary outcome is the change in emotional functioning. Study selection, data extraction and assessment of the risk of bias will be performed independently by two or more reviewers. Revman software (v.5.3) will be used to perform the assessment of the risk of bias and data synthesis.Ethics and disseminationEthics approval is not be needed because the data will not contain individual patient data, and there are no concerns about privacy. The results of this meta-analysis will be disseminated through publication in a peer-reviewed journal or relevant conference.Trial registration numberCRD42019139433.


2020 ◽  
Vol 12 (5) ◽  
pp. 470-477 ◽  
Author(s):  
Andrés F. Loaiza-Betancur ◽  
Iván Chulvi-Medrano

Context: High blood pressure is one of the leading preventable causes of cardiovascular death worldwide. In this regard, several studies have shown interest in the benefits of isometric exercise on blood pressure regulation. Objective: To assess whether low-intensity isometric handgrip exercise (LI-IHE) is an effective strategy to lower blood pressure levels in prehypertensive and hypertensive patients. Data Source: This study was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement and registered with PROSPERO. Potentially eligible studies were identified after a systematic search conducted on 4 international databases: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), PEDro, and SPORTDiscus. Study Selection: We included randomized controlled trials that comprised patients who received LI-IHE. Study Design: Systematic review with meta-analysis. Level of Evidence: Level 3. Data Extraction: Data related to patient characteristics, exercise programs, risk-of-bias assessment, and outcomes of interest were systematically reviewed independently by 2 authors. Results: The following reductions (mean differences) were observed after LI-IHE: systolic blood pressure (SBP), (MD) = −5.43 mm Hg; (95% CI, −8.47 to −2.39; P = 0.0005); diastolic blood pressure (DBP), −2.41 mm Hg (95% CI, −4.33 to −0.48; P = 0.01); mean arterial pressure (MAP), −1.28 mm Hg (95% CI, −2.99 to 0.44; P = 0.14). Conclusion: LI-IHE seems to lower SBP, DBP, and MAP values in prehypertensive and hypertensive adults. It appears that LI-IHE reduces, in greater magnitude, blood pressure levels in hypertensive patients, specifically in patients aged <45 years, those who are overweight, and those on medications. Nevertheless, substantial heterogeneity in the main results and in the analyses by subgroups generated uncertainty about the real reduction magnitude that LI-IHE can produce on blood pressure.


2021 ◽  
Author(s):  
Mats Baxter ◽  
Jurgen Schwarze ◽  
Andrew Bush ◽  
Aziz Sheikh

Abstract IntroductionMobile health (mHealth) is a potential tool to improve nasal corticosteroid (NCS) adherence in allergic rhinitis (AR), which remains largely poor and inconsistent for many. We plan to undertake a systematic review to synthesise the evidence on the efficacy of mHealth interventions to improve NCS adherence in AR. Methods and analysisA systematic search will be conducted in the electronic databases MEDLINE, EMBASE and CENTRAL (Cochrane Central Register of Controlled Trials), filtered for publication dates between January 2010 and August 2020. The search is scheduled to commence in August 2020. We will scan reference lists of included studies for additional eligible papers. Relevant unpublished or in-progress trials will be searched for through trial registries. Randomised controlled trials that examine the efficacy of mHealth interventions to improve NCS adherence in AR are to be included. Two reviewers will independently screen and extract relevant data from the included studies and perform a risk-of-bias assessment using the Cochrane risk of bias tool 2.0. We will perform a narrative synthesis with relevant data tables and, if deemed clinically relevant and statistically adequate, meta-analyses using random-effects modelling. The Preferred Reporting Items for Systematic review and Meta-Analysis (PRISMA) statement will be used to help guide the reporting of this review. Ethics and disseminationSince this systematic review will be exclusively based on published and retrievable literature, no ethics approval will be sought. The findings of this systematic review will be disseminated at appropriate conferences/webinars while being published in an open access peer-reviewed journal.Registration: In accordance with the guidelines, our systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 27th August 2020. PROSPERO registration number CRD42020198879.


2020 ◽  
Author(s):  
Isabel Fialho Fontenele Garcia ◽  
Vinicius Cavalheri ◽  
Adriana Claudia Lunardi

Abstract Background Abdominal cancer surgeries have a high incidence of postoperative complications. One strategy to prevent postoperative complications is preoperative exercise training. There are no systematic reviews that have compared the effects of preoperative exercise training programs of different length, frequency and duration on pre and postoperative clinical outcomes as well as on length of hospital stay (LOS) and in-hospital and late mortality in people with abdominal cancer. Methods Searches for randomised controlled trials (RCTs) of preoperative exercise training for people undergoing major surgery for abdominal cancer will be conducted in Pubmed, EMBASE, PEDro (Physiotherapy Evidence Database) and the Cochrane Library. There will be no restrictions on the language or date of publication in the search. The primary outcomes of the systematic review will be incidence of postoperative pulmonary complications as well as post-intervention and postoperative exercise capacity. The risk of bias of included RCTs will be assessed using the PEDro scale. The quality of evidence will be rated using the GRADE system (Grading of Recommendations Assessment, Development and Evaluation). Subgroup analyzes will be conducted based on: intervention performed with or without supervision; types of exercises; and frequency and duration of the intervention. Discussion Our hypothesis is that preoperative exercise training will reduce the incidence of postoperative pulmonary complications in people undergoing major surgery for abdominal cancer by improving their preoperative exercise capacity. We will also explore the effects of the program on LOS and mortality. Systematic review registration: This systematic review protocol was registered with PROSPERO (Prospective International Register of Systematic Reviews) (number CRD42020199765).


2019 ◽  
Vol 8 (1) ◽  
Author(s):  
Naiane Teixeira Bastos de Oliveira ◽  
Irlei dos Santos ◽  
Gisela Cristiane Miyamoto ◽  
Cristina Maria Nunes Cabral

Abstract Background Chronic musculoskeletal pain affects the quality of life of older adults by interfering in their ability to perform activities of daily living. Aerobic exercise programs have been used in the treatment of various health conditions, including musculoskeletal disorders. However, there is still little evidence on the effects of aerobic exercise for the treatment of older adults with chronic musculoskeletal pain. Thus, the objective of this study is to assess the effects of aerobic exercise in improving pain and function of older adults with chronic pain as a consequence of different chronic musculoskeletal conditions. Methods The databases to be used in the search are PubMed, EMBASE, CINAHL, PEDro, and Cochrane Central Register of Controlled Trials (CENTRAL). Randomized controlled trials that used aerobic exercise in the treatment of older adults with chronic musculoskeletal pain will be included. Primary outcomes will be pain and function. We will use the PEDro scale to evaluate the methodological quality and statistical description of each included study, and the strength of the recommendations will be summarized using GRADE. Discussion The results of this systematic review will provide a synthesis of the current evidence on the effects of aerobic exercise in the treatment of older adults with chronic musculoskeletal pain. In addition, this information can help health professionals in decision-making about the use of aerobic exercise in the treatment of older adults with chronic musculoskeletal pain. Ethics and dissemination This systematic review was recorded prospectively, and the results will be part of a doctoral thesis to be published in a peer-reviewed international journal and possibly presented at international conferences. Systematic review registration PROSPERO, CRD42019118903.


2020 ◽  
pp. 026921552095193
Author(s):  
Alberto Saavedra-García ◽  
Jose A Moral-Munoz ◽  
David Lucena-Anton

Objective: To evaluate the current evidence on the effectiveness of simultaneous combination of mirror therapy and electrical stimulation in the recovery of upper limb motor function after stroke, compared with conventional therapy, mirror therapy or electrical stimulation isolated. Data sources: Articles published in PubMed, Web of Science, Scopus, Physiotherapy Evidence Database (PEDro), Cochrane Central register of controlled trials and ScienceDirect up to July 2020. Review methods: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed. Methodological quality was assessed using the PEDro tool. The RevMan 5.4 statistical software was used to obtain the meta-analysis, through the standardized mean difference and 95% confidence intervals (CI), and to evaluate the risk of bias. The GRADE approach was employed to assess the certainty of evidence. Results: Eight articles were included in this systematic review, seven were included in the meta-analysis. A total of 314 participants were analyzed. The overall quality of the articles included in this review was good. There was no overall significant mean difference on upper limb motor function after stroke using the Upper-Extremity Fugl-Meyer Assessment by 1.56 (95% CI = –2.08, 5.20; P = 0.40; moderate-certainty evidence) and the Box and Block Test results by 1.39 (95% CI = –2.14, 4.92; P = 0.44; high-certainty evidence). There was overall significant difference in the Action Research Arm Test by 3.54 (95% CI = 0.18, 6.90; P = 0.04; high-certainty evidence). Conclusion: Direct scientific evidence about the effectiveness of the combined therapy of mirror therapy and electrical stimulation simultaneously for the improvement of the upper limb motor function after stroke is lacking. Further high-quality and well-designed research is needed.


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