scholarly journals The effect of the vitamin D and calcium on the quality of life of infants

2021 ◽  
Vol 16 (7) ◽  
pp. 467-473
Author(s):  
A.E. Abaturov ◽  
O.L. Kryvusha ◽  
V.L. Babуch

Background. Relevant in pediatrics is the use of indicators of quality of life of children to personify the treatment process, monitoring the course of the disease. In recent years, there has been increasing research on the role of vitamin D and calcium in the human body. The study was aimed to assess the quality of life of infants and to establish the possibility of medical correction of the main indicators of quality of life under the influence of the combined use of vitamin D and calcium. Materials and methods. We observed 30 clinically healthy infants who received 2.5 ml of vitamin D and calcium 3 times a day for 2 months. We have created our questionnaire on the quality of life of infants. Methods of variation statistics are used. Results. Based on the correlation analysis in infants before treatment, there was found a positive relationship between quality of life and the state of biological resistance (r = +0.51; p < 0.05); natural feeding (r = +0.56; p < 0.05); symptoms of functional gastrointestinal disorders (r = +0.58; p < 0.05); parameters of emotional status (r = +0.62; p < 0.05); signs of autonomic dysfunction syndrome (r = +0.63; p < 0.05); neuropsychological development (r = +0.65; p < 0.05); features of adaptability (r = +0.66; p < 0.05). The results of the treatment with vitamin D and calcium in the study of the correlation diagram of the relationship between quality of life and the established indicators of the development of infants demonstrated no correlation between the quality of life and symptoms of functional gastrointestinal disorders and symptoms of autonomic dysfunction. After treatment, there was a decrease in the strength of the correlation between the quality of life of infants and the parameters of emotional status (r = +0.36; p < 0.05); indicators of neuropsychological development (r = +0.35; p < 0.05), and ability to adapt (r = +0.44; p < 0.05). Conclusions. The сombined use of vitamin D and calcium in the recommended dose of 2.5 ml 3 times a day for 2 months is characterized by a high safety profile, improves the quality of life of a child, and can be recommended for infants.

2020 ◽  
Vol 7 (10) ◽  
pp. 2015
Author(s):  
Shrish Bhatnagar ◽  
Roshan R. Mane ◽  
Irfan A. Shaikh ◽  
Ganesh Kadhe

Background: Functional gastrointestinal disorders (FGIDs) in infants and toddlers possess extensive burden to the parents and healthcare professionals. Guidelines addressing the practices in diagnosis and management of FGIDs in infants in Indian subcontinent is unavailable. Hence this study assessed current knowledge, attitude and practice of pediatricians in diagnosis and treatment of FGIDs.Methods: A cross-sectional survey based on a structured questionnaire assessed pediatrician’s knowledge about prevalence and profile of most common GI disorders in pediatric age groups (birth to 12 months), association of FGIDs with different feeding practices, impact of FGID on quality of life, various management options and physician preferred method of treatment.Results: Colic was rated as the most common GI disorder, followed by gassiness/fussiness, regurgitation and constipation. About 59% pediatricians come across FGIDs more in formula-fed infants compared to breastfed infants (4.2%) and 93.9% pediatricians affirm that FGIDs affect quality of life. Approximately 91% pediatricians believed reassurance and education was the best management option, which was also reported as the preferred mode of management by about 89% pediatricians, whereas pharmacological therapies were the least preferred (1.6%). For breastfed infants suffering with regurgitation, colic or constipation, majority pediatricians opted for switching to 100% whey partially hydrolysed protein formula; sequentially followed by use of pre/probiotics and switch to extensively hydrolyzed protein formula.Conclusions: Parental education and reassurance offer an ideal mode of management of FGIDs. Partially hydrolysed protein formula may be considered one of the best management options irrespective of the FGID condition in infants who are breastfeed.


2020 ◽  
Vol 11 ◽  
Author(s):  
Chloé Melchior ◽  
Charlotte Desprez ◽  
Fabien Wuestenberghs ◽  
Anne-Marie Leroi ◽  
Antoine Lemaire ◽  
...  

Objective: We aimed to determine the burden of opioid consumption in a cohort of patients with functional gastrointestinal disorders.Methods: All patients diagnosed with functional gastrointestinal disorders and referred to our university hospital were evaluated from 2013 to the beginning of 2019. Irritable bowel syndrome and functional dyspepsia diagnoses were determined according to Rome criteria and severity according to irritable bowel syndrome severity scoring system. Vomiting was quantified using a 5-point Likert scale, and constipation severity was measured using the Knowles-Eccersley-Scott-Symptom questionnaires. Quality of life was quantified by the GastroIntestinal Quality of Life Index. Patients were categorized as being treated on a chronic basis with either tramadol, step II opioids, step III opioids or as being opioid-free.Results: 2933 consecutive patients were included. In our cohort, 12.5% had only irritable bowel syndrome, 39.3% had only functional dyspepsia, 24.9% had a combination of both, and 23.4% had other functional gastrointestinal disorders. Among them, the consumption of tramadol, step II (tramadol excluded) and step III opioids was 1.8, 1.3 and 0.3 % respectively in 2013 and 4.3, 3.4 and 1.9% in 2018 (p &lt; 0.03). Opioid consumption was associated with increased vomiting (p = 0.0168), constipation (p &lt; 0.0001), symptom severity (p &lt; 0.001), more altered quality of life (p &lt; 0.0001) and higher depression score (p = 0.0045).Conclusion: In functional gastrointestinal disorders, opioid consumption has increased in the last years and is associated with more GI symptoms (vomiting, constipation and GI severity), higher depression and more altered quality of life.


2018 ◽  
Vol 107 (7) ◽  
pp. 1276-1282 ◽  
Author(s):  
Marc Bellaiche ◽  
Raish Oozeer ◽  
Geraldine Gerardi-Temporel ◽  
Christophe Faure ◽  
Yvan Vandenplas

2019 ◽  
Vol 9 (5) ◽  
pp. 381-390
Author(s):  
Ruth Ann Marrie ◽  
Stella Leung ◽  
Tuula Tyry ◽  
Gary R. Cutter ◽  
Robert Fox ◽  
...  

ObjectiveTo determine the prevalence of functional gastrointestinal disorders, the demographic and clinical characteristics associated with the presence of functional gastrointestinal disorders, and the effects of these disorders with health-related quality of life (HRQOL) in a large, diverse population of persons with MS.MethodsIn 2014, we surveyed participants in the North American Research Committee on Multiple Sclerosis registry regarding functional gastrointestinal disorders using the Rome III questionnaire. Participants also reported their sociodemographic characteristics, disability status using Patient Determined Disease Steps, the presence of comorbid depression and anxiety, health behaviors, and HRQOL using the RAND-12. We determined the prevalence of each gastrointestinal disorder using the Rome III criteria. Using multivariable logistic regression models, we assessed the factors associated with the presence of each bowel disorder. Using linear regression, we evaluated the association between functional gastrointestinal disorders and HRQOL.ResultsOf 6,312 eligible respondents, 76.5% were female, with a mean (SD) age of 58.3 (10.2) years. Forty-two percent of respondents (n = 2,647) had a functional gastrointestinal disorder, most often irritable bowel syndrome (IBS), which affected 28.2% of participants. The prevalence of all functional gastrointestinal disorders increased with greater disability, and the prevalence of IBS increased with longer disease duration. After adjusting for sociodemographic and clinical characteristics, functional gastrointestinal disorders were associated with lower physical and mental HRQOL (both p < 0.0001).ConclusionsFunctional gastrointestinal disorders are common in MS and are associated with reduced HRQOL.


Sign in / Sign up

Export Citation Format

Share Document