scholarly journals UMBILICAL CORD BLOOD HEMATOLOGY IN RELATION WITH MATERNAL ANEMIA: A PRELIMINARY STUDY

Author(s):  
Rumi Debbarma ◽  
Pankaj Pankaj ◽  
M. Anita Devi

Objectives: The aim of this study was to observe any umbilical cord blood hematological changes in relation to maternal anemia.Methods: We conducted a cross-sectional study on 220 neonates and their mothers from August 1, 2015, to July 31, 2016, in collaboration with the Department of Obstetrics and Gynaecology, Regional Institute of Medical Sciences, Imphal, India. Immediately after vaginal delivery of baby, umbilical cord was clamped and blood was collected in EDTA vials and analyzed using automated hematoanalyzer.Results: Neonates of non-anemic mothers had significantly higher level of hemoglobin concentration than neonates of anemic mothers. Total leukocyte count (TLC) was slightly higher in neonates of non-anemic mothers as compared to neonates of anemic mothers. Platelet count was slightly higher in neonates of anemic mothers as compared to non-anemic mothers, but platelet crit, mean platelet volume, and platelet cell distribution width were slightly higher in neonates of non-anemic mothers than neonates anemic mothers.Conclusions: It was a preliminary study. A similar type of the study must be conducted in future to comprehend the effect of various other factors affecting delivery such as maternal anemia, diet, and environment on blood parameters of newborns.

2009 ◽  
Vol 61 (4) ◽  
pp. 791-796 ◽  
Author(s):  
M.L.B. Cápua ◽  
A.E. Santana ◽  
A.P.M. Nakage ◽  
A.V. Godoy ◽  
A. Kataoka

The hematological parameters red blood cells (RBC) and total white blood cells (WBC) counts, hematocrit, hemoglobin concentration, and RBC indexes (median corpuscular volume and median corpuscular hemoglobin concentration) were determined and T CD5+ lymphocytes and CD4+ and CD8+ subpopulations of the umbilical cord blood (UCB) of dogs were quantified by the cytofluorimetric technique. Nine adult Beagles, from two do five-year old, were used as control. The umbilical cord blood (UCB) was collected from 20 neonate dogs. The method for the UCB collection was adequate to obtain sufficient quantity of blood for the accomplishment of the hematological analyses and lymphocyte quantification. Cytoscopic preparations of the UCB suggested high erythropoietic activity. There was no difference for the global leukocyte and lymphocyte counts between the groups. UCB T lymphocyte counts were lower than those obtained for adult dogs. The proportion of CD4:CD8 showed a great dominance of T CD4+ cells over T CD8+ lymphocytes in UCB.


2017 ◽  
Vol 80 (7) ◽  
pp. 442-451 ◽  
Author(s):  
Shih-Hui Huang ◽  
Ken-Pen Weng ◽  
Ching-Chiang Lin ◽  
Chung-Cheng Wang ◽  
Charles Tzu-Chi Lee ◽  
...  

2012 ◽  
Vol 64 (5) ◽  
pp. 511-521 ◽  
Author(s):  
Tatiana Taís Sibov ◽  
P. Severino ◽  
L. C. Marti ◽  
L. F. Pavon ◽  
D. M. Oliveira ◽  
...  

Author(s):  
Kyung Eun Lee ◽  
Young Seoub Hong ◽  
Dae Seon Kim ◽  
Myoung Seok Han ◽  
Byeng Chul Yu ◽  
...  

2016 ◽  
Vol 33 (9) ◽  
pp. 1136-1147 ◽  
Author(s):  
Felix Scholkmann ◽  
Giuseppe Miscio ◽  
Roberto Tarquini ◽  
Alberto Bosi ◽  
Rosa Rubino ◽  
...  

2016 ◽  
Vol 38 (1) ◽  
pp. 40-49 ◽  
Author(s):  
Victor Mardini ◽  
Luis Augusto Rohde ◽  
Keila Maria Mendes Ceresér ◽  
Carolina de Moura Gubert ◽  
Emily Galvão da Silva ◽  
...  

Introduction Prenatal cocaine exposure (PCE) is associated with neurobehavioral problems during childhood and adolescence. Early activation of the inflammatory response may contribute to such changes. Our aim was to compare inflammatory markers (IL-6 and IL-10) both in umbilical cord blood and in maternal peripheral blood at delivery between newborns with history of crack/cocaine exposure in utero and non-exposed newborns. Methods In this cross-sectional study, 57 newborns with a history of crack/cocaine exposure in utero (EN) and 99 non-exposed newborns (NEN) were compared for IL-6 and IL-10 levels. Sociodemographic and perinatal data, maternal psychopathology, consumption of nicotine and other substances were systematically collected in cases and controls. Results After adjusting for potential confounders, mean IL-6 was significantly higher in EN than in NEN (10,208.54, 95% confidence interval [95%CI] 1,328.54-19,088.55 vs. 2,323.03, 95%CI 1,484.64-3,161.21; p = 0.007; generalized linear model [GLM]). Mean IL-10 was also significantly higher in EN than in NEN (432.22, 95%CI 51.44-812.88 vs. 75.52, 95%CI 5.64-145.39, p = 0.014; GLM). Adjusted postpartum measures of IL-6 were significantly higher in mothers with a history of crack/cocaine use (25,160.05, 95%CI 10,958.15-39,361.99 vs. 8,902.14, 95%CI 5,774.97-12,029.32; p = 0.007; GLM), with no significant differences for IL-10. There was no correlation between maternal and neonatal cytokine levels (Spearman test, p ≥ 0.28 for all measures). Conclusions IL-6 and IL-10 might be early biomarkers of PCE in newborns. These findings could help to elucidate neurobiological pathways underlying neurodevelopmental changes and broaden the range of possibilities for early intervention.


2017 ◽  
Vol 24 (25) ◽  
pp. 20736-20746 ◽  
Author(s):  
María Martha Quintana ◽  
Berta Vera ◽  
Gladis Magnarelli ◽  
Natalia Guiñazú ◽  
María Gabriela Rovedatti

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