scholarly journals MEDICINAL USES, BIOLOGICAL AND PHYTOCHEMICAL PROPERTIES OF HELICHRYSUM FOETIDUM (L.) MOENCH. (ASTERACEAE)

2019 ◽  
pp. 13-18 ◽  
Author(s):  
ALFRED MAROYI
Keyword(s):  
Therapeutic Potential ◽  
Biological Activities ◽  
Medicinal Uses ◽  
Eye Infections ◽  
Additional Information ◽  
Phytochemical Compounds ◽  
Cytotoxicity Activities ◽  
Search For Information ◽  
The University ◽  
Phytochemical Components

Helichrysum foetidum is a medicinal plant species with various medicinal applications among different ethnic groups in Africa, Asia, and Europe. This review was aimed at providing a critical appraisal of the existing medicinal uses, biological activities, and phytochemical components of H. foetidum. Literature search for information on medicinal uses, biological activities, and phytochemical components of H. foetidum was conducted using various online search engines such as Scopus, Google Scholar, Mendeley, and Web of Science. Additional information on these aspects was sourced from the university library. Literature studies revealed that H. foetidum is mainly used to induce trances and as herbal medicine against wounds, sores, dysmenorrhea, eye infections, influenza, and as a sedative. Phytochemical compounds identified from the species include chalcones, diterpenoids, flavanols, flavonoids, phenolics, phenols, and proanthocyanidins. Pharmacological studies revealed that H. foetidum extracts and compounds have antibacterial, antifungal, antiviral, antioxidant, protease-inhibiting, and cytotoxicity activities. There is a need for advanced phytochemical and pharmacological evaluations and clinical trials aimed at evaluating the therapeutic potential of H. foetidum in Africa, Asia, and Europe.

scholarly journals HELICHRYSUM LONGIFOLIUM AND HELICHRYSUM PEDUNCULATUM: A COMPARATIVE ANALYSIS OF THEIR MEDICINAL USES, CHEMISTRY AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 41-46
Author(s):  
ALFRED MAROYI
Keyword(s):  
Biological Activities ◽  
Herbal Medicines ◽  
Pharmaceutical Products ◽  
Medicinal Uses ◽  
Additional Information ◽  
Medicinal Use ◽  
Need To Evaluate ◽  
History Of ◽  
Cytotoxicity Activities ◽  
The University

Helichrysum longifolium and Helichrysum pedunculatum have a long history of medicinal use, particularly managing wounds acquired during male circumcision rites in South Africa. There is a need to evaluate the existence of any correlation between the ethnomedicinal applications, the phytochemistry and pharmacological properties of the species. Therefore, in this review, analyses of the botanical, medicinal, and chemical and biological activities of H. longifolium and H. pedunculatum are presented as well as exploring the potential of the two species as important sources of health and pharmaceutical products. Information on the botany, medicinal uses, and phytochemistry and biological activities of H. longifolium and H. pedunculatum was assembled from several internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was sourced from journal articles, scientific reports, theses, books, and book chapters obtained from the University library. This study showed that alkaloids, flavonoids, linoleic acid, oleic acid, phenol, proanthocyanidin, saponins, and tannins have been identified from the leaves of H. longifolium and H. pedunculatum. The pharmacological research showed that H. longifolium and H. pedunculatum extracts and compounds isolated from the species have antibacterial, antifungal, anti-inflammatory, antioxidant, antiplasmodial, antiprotozoal, and cytotoxicity activities. For local communities to use H. longifolium and H. pedunculatum extracts with confidence as herbal medicines, there is a need for extensive phytochemical and pharmacological studies. Further research is required to establish the safety profiles of different H. longifolium and H. pedunculatum preparations.

scholarly journals HELICHRYSUM CYMOSUM (L.) D.DON (ASTERACEAE): MEDICINAL USES, CHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 19-26
Author(s):  
ALFRED MAROYI
Keyword(s):  
Biological Activities ◽  
Future Research ◽  
Pharmacological Properties ◽  
Journal Articles ◽  
Tropical Africa ◽  
Medicinal Uses ◽  
Additional Information ◽  
Cytotoxicity Activities ◽  
The University ◽  
Anti Hiv

Helichrysum cymosum is a valuable and well-known medicinal plant in tropical Africa. The current study critically reviewed the medicinal uses, phytochemistry and biological activities of H. cymosum. Information on medicinal uses, phytochemistry and biological activities of H. cymosum, was collected from multiple internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was gathered from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University library. This study showed that H. cymosum is traditionally used as a purgative, ritual incense, and magical purposes and as herbal medicine for colds, cough, fever, headache, and wounds. Ethnopharmacological research revealed that H. cymosum extracts and compounds isolated from the species have antibacterial, antioxidant, antifungal, antiviral, anti-HIV, anti-inflammatory, antimalarial, and cytotoxicity activities. This research showed that H. cymosum is an integral part of indigenous pharmacopeia in tropical Africa, but there is lack of correlation between medicinal uses and existing pharmacological properties of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of H. cymosum extracts and compounds isolated from the species.

scholarly journals A SYNTHESIS AND REVIEW OF MEDICINAL USES, PHYTOCHEMISTRY AND BIOLOGICAL ACTIVITIES OF HELICHRYSUM ODORATISSIMUM (L.) SWEET

2019 ◽  
pp. 15-23 ◽  
Author(s):  
ALFRED MAROYI
Keyword(s):  
Animal Studies ◽  
Randomized Clinical Trials ◽  
Biological Activities ◽  
Journal Articles ◽  
Medicinal Uses ◽  
Respiratory Problems ◽  
Additional Information ◽  
Cytotoxicity Activities ◽  
The University ◽  
Ethnomedicinal Uses

Helichrysum odoratissimum is an important medicinal plant species in tropical Africa. The current study critically reviewed the medicinal uses, phytochemistry and biological activities of H. odoratissimum. Information on medicinal uses, phytochemistry and biological activities of H. odoratissimum were collected from multiple internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information was gathered from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the university library. This study showed that H. odoratissimum is mainly used as an herbal medicine for insomnia, menstrual pain and sterility, and wounds and respiratory problems. Pharmacological research revealed that H. odoratissimum extracts and compounds isolated from the species have antibacterial, antimycobacterial, antifungal, anti-inflammatory, antioxidant, hepatoprotection, and hypoglycemic and cytotoxicity activities. There is a need to validate the documented ethnomedicinal uses of H. odoratissimum through phytochemical and pharmacological studies. Therefore, future studies should address these knowledge gaps through experimental animal studies, randomized clinical trials, and target-organ toxicity studies involving H. odoratissimum crude extracts and compounds isolated from the species.

scholarly journals HELICHRYSUM PETIOLARE HILLIARD AND B. L. BURTT: A REVIEW OF ITS MEDICINAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 32-37 ◽  
Author(s):  
ALFRED MAROYI
Keyword(s):  
South Africa ◽  
Respiratory Infections ◽  
Biological Activities ◽  
Future Research ◽  
Journal Articles ◽  
Medicinal Uses ◽  
Additional Information ◽  
Cytotoxicity Activities ◽  
The University ◽  
Phytochemical Studies

Helichrysum petiolare is a valuable and well-known medicinal herb in South Africa. A comprehensive review of phytochemical, medicinal uses, and biological activities of H. petiolare is presented in this study. Information on biological activities, medicinal uses, and phytochemistry of H. petiolare was gathered from several internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, PubMed, SciFinder, and BMC. Additional information on these aspects was sourced from pre-electronic sources such as journal articles, scientific reports, theses, books, and book chapters obtained from the University library. The current study revealed that H. petiolare is mainly used as herbal medicine for respiratory infections, diabetes, fever, headache, heart problem, high blood pressure, pain, reproductive problems, and wounds. Phytochemical studies showed that H. petiolare extracts and compounds isolated from the species have antifungal, anti-inflammatory, antibacterial, antioxidant, antityrosinase, antigenotoxicity, and cytotoxicity activities. This research showed that H. petiolare is an integral part of indigenous pharmacopeia in South Africa, but there is the lack of alignment between the known medicinal applications, phytochemistry, and biological activities of the species. Therefore, future research should focus on evaluating the chemical and pharmacological properties of H. petiolare extracts and compounds associated with the species.

scholarly journals BALANITES MAUGHAMII SPRAGUE (ZYGOPHYLLACEAE) IN TROPICAL AFRICA: A SYNTHESIS AND REVIEW OF ITS CHEMISTRY, PHARMACOLOGY, AND MEDICINAL POTENTIAL

2019 ◽  
pp. 85-90
Author(s):  
ALFRED MAROYI
Keyword(s):  
Biological Activities ◽  
Future Research ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Additional Information ◽  
Fish Poison ◽  
Documented Information ◽  
Phytochemical Compounds ◽  
The University ◽  
Online Sources

Balanites maughamii is an important medicinal plant species in Southern Africa. This study is aimed at providing a critical review of the biological activities, phytochemistry, and medicinal uses of B. maughamii. Documented information on biological activities, medicinal uses, and phytochemistry of B. maughamii was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the biological activities, phytochemistry and medicinal uses of B. maughamii were collected from pre-electronic sources such as book chapters, books, journal articles, theses, and scientific publications sourced from the university library. This study showed that the bark, fruits, leaves, and roots of B. maughamii are traditionally used for magical purposes, as emetic, tonic, fish poison, insecticidal, and herbal medicine for bilharzia. Phytochemical compounds identified from the bark, fruits, and leaves of B. maughamii are aliphatic alcohols, aliphatic ketones, benzenoid compounds, aliphatic acids, amino acids, coumarin, aliphatic esters, flavonoids, aliphatic aldehydes, and sterol. Pharmacological research revealed that B. maughamii extracts have adulticidal, antibacterial, antiplasmodial, bitterness, molluscicidal, and mutagenic activities. Future research should focus on evaluating the phytochemical, pharmacological, and toxicological properties of B. maughamii crude extracts as well as compounds isolated from the species.

scholarly journals Helichrysum nudifolium (L.) Less.: Review of its Medicinal Uses, Phytochemistry and Biological Activities

2019 ◽  
Vol 9 (3) ◽  
pp. 189-194
Author(s):  
Alfred Maroyi
Keyword(s):  
Animal Studies ◽  
Randomized Clinical Trials ◽  
Biological Activities ◽  
Benzodiazepine Receptor ◽  
Ethnoveterinary Medicine ◽  
Medicinal Uses ◽  
Additional Information ◽  
Pregnancy And Postpartum ◽  
Cytotoxicity Activities ◽  
The University

Helichrysum nudifolium is a valuable and well-known medicinal plant species in southern Africa. The current study critically reviewed the medicinal uses, phytochemistry and biological activities of H. nudifolium. Information on medicinal uses, phytochemistry and biological activities of H. nudifolium was collected from multiple internet sources which included Scopus, Google Scholar, Elsevier, Science Direct, Web of Science, Pubmed, SciFinder and BMC. Additional information was gathered from pre-electronic sources such as journal articles, scientific reports, theses, books and book chapters obtained from the University library. This study showed that H. nudifolium is mainly used as ethnoveterinary medicine, as colic and herbal medicine for fever, headache, swellings, infertility, pregnancy and postpartum problems. Pharmacological research revealed that H. nudifolium extracts have antibacterial, antimycobacterial, antifungal, anti-HIV, GABAA-benzodiazepine receptor-binding, anticancer, anti-inflammatory, antiplasmodial, antiprotozoal and cytotoxicity activities. There is need for experimental animal studies, randomized clinical trials and target-organ toxicity studies involving H. nudifolium crude extracts and compounds isolated from the species. Future should also focus on evaluation of pharmacological properties of compounds isolated from H. nudifolium.

scholarly journals REVIEW OF MEDICINAL USES, PHYTOCHEMISTRY, AND PHARMACOLOGICAL PROPERTIES OF DRIMIA ELATA

2019 ◽  
pp. 37-44
Author(s):  
ALFRED MAROYI
Keyword(s):  
Journal Articles ◽  
Tropical Africa ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
In Vivo Experiments ◽  
Phytochemical Compounds ◽  
Cytotoxicity Activities ◽  
Acetylcholinesterase Enzyme ◽  
The University

Drimia elata is an important and well-known medicinal plant in tropical Africa. This study critically reviewed the medicinal applications, phytochemistry, and pharmacological activities of D. elata. Literature on medicinal applications, phytochemical, and pharmacological activities of D. elata was collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, PubMed, BMC, ScienceDirect, and Scopus. Complementary information was gathered from pre-electronic sources such as books, book chapters, theses, scientific reports, and journal articles obtained from the university library. This study showed that D. elata is used for treating several medical conditions, particularly general ailments, blood and cardiovascular system, reproductive system and sexual health, urinary system, infections and infestations, digestive system, respiratory system, and muscular-skeletal system disorders. Phytochemical compounds identified from the species include bufadienolides, alkaloids, aromatic acids, flavonoids, phlobatannins, saponins, steroids, tannins, and terpenoids. Ethnopharmacological research revealed that D. elata extracts have acetylcholinesterase enzyme inhibitory, antibacterial, antifungal, antimycobaceterial, anticancer, anti-inflammatory, antioxidant, hemagglutinating, and cytotoxicity activities. D. elata should be subjected to extensive in vivo experiments and also future studies should focus on how potential toxic components of the species can be managed when it is used as herbal medicine.

scholarly journals BERCHEMIA ZEYHERI (SOND.) GRUBOV: MEDICINAL USES, PHYTOCHEMISTRY, AND PHARMACOLOGICAL PROPERTIES

2019 ◽  
pp. 14-18
Author(s):  
ALFRED MAROYI
Keyword(s):  
Herbal Medicine ◽  
Biological Activities ◽  
Ethnoveterinary Medicine ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Additional Information ◽  
Aerial Parts ◽  
Toxicological Studies ◽  
Deciduous Fruit ◽  
The University

Berchemia zeyheri is a small-to-medium-sized deciduous fruit tree widely used as herbal medicine. This study was aimed at providing a critical review of the medicinal uses, phytochemistry, and biological activities of B. zeyheri. Documented information on the biological activities, medicinal uses, and phytochemistry of B. zeyheri was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, ScienceDirect, Elsevier, PubMed, and Web of Science. Additional information on the biological activities, phytochemistry, and medicinal uses of B. zeyheri was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications obtained from the university library. This study showed that the bark and roots of B. zeyheri are used for magical purposes and as herbal medicine for anemia, backache, baby’s navel problems, cough, dysentery, headache, rectal ulcers, stomach problems, tonic, and vomiting and ethnoveterinary medicine for infectious diseases in cattle. Phytochemical analyses revealed that the aerial parts, bark, and heartwood of B. zeyheri are characterized by alkaloids, flavonoids, glycosides, polyphenols, and steroids. Pharmacological research revealed that B. zeyheri crude extracts have anthelmintic, antibacterial, antioxidant, and toxicity activities. Future ethnopharmacological research should focus on conducting detailed phytochemical, pharmacological, and toxicological studies.

scholarly journals PHYTOCHEMICAL AND ETHNOPHARMACOLOGICAL REVIEW OF HETEROPYXIS NATALENSIS

2019 ◽  
pp. 8-15 ◽  
Author(s):  
ALFRED MAROYI
Keyword(s):  
Therapeutic Potential ◽  
Herbal Medicines ◽  
Mechanisms Of Action ◽  
Bleeding Disorders ◽  
Ethnoveterinary Medicine ◽  
Medicinal Uses ◽  
Pharmacological Studies ◽  
Phytochemical Compounds ◽  
The University ◽  
Conference Papers

The bark, leaves, roots, and twigs of Heteropyxis natalensis are widely used as herbal medicines in Southern Africa. The aim of this study was to review the phytochemical and ethnopharmacological properties of H. natalensis so as to provide baseline data required for evaluating the therapeutic potential of the species. Information on the botanical profile, medicinal uses, phytochemistry, and pharmacological properties of H. natalensis was undertaken using databases such as ScienceDirect, SciFinder, PubMed, Google Scholar, Medline, SCOPUS, EThOS, ProQuest, OATD, and open-thesis. Pre-electronic literature of conference papers, scientific articles, books, book chapters, dissertations, and theses were carried out at the university library. Literature search revealed that H. natalensis is used as an aphrodisiac, anti-infection, blood purifier, decongestant, for weaning, ethnoveterinary medicine and as herbal medicine for bleeding disorders, gums, nose, colds, gum infections, impotence, menorrhagia, respiratory disorders, toothache, and wounds. Phytochemical compounds identified from the species include essential oils, 3β-hydroxylup-20(29)-en-28-al, (E)-1-(2’,4’-dihyroxy,5’- methoxy,3’-methylphenyl)-3-phenylprop-2-en-1-one, (2E)-2-[(2E)-1-hydroxy-3-phenylprop-2-en-1-ylidene]-5-methoxy-6,6-dimethylcyclohex-4-ene- 1,3-dione, 2’,4’-dihydroxy-6’-methoxy-3’,5’-dimethylchalcone, 3’,4’,5’-tri-O-methyl-3,4-methylenedioxy ellagic acid, 3,5,7-trihydroxyflavan, 5-hydroxy- 7-methoxy-6-methylflavanone, aurentiacin A, betulinic acid, cardamomin, lupenone, lupeol, quercetin, and sitost-4-en-3-one. Pharmacological studies revealed that H. natalensis extracts and compounds have antibacterial, antimycobacterial, antifungal, antioxidant, anti-inflammatory, cytotoxicity, and pro-inflammatory activities. Detailed studies are required to establish the efficacy, clinical relevance, safety and mechanisms of action of the plant extracts, and compounds of H. natalensis.

scholarly journals Review of Medicinal uses, Phytochemistry and Biological Activities of Antidesma laciniatum and A. membranaceum -

2020 ◽  
Vol 10 (5) ◽  
pp. 257-263
Author(s):  
Alfred Maroyi
Keyword(s):  
Biological Activities ◽  
Clinical Effectiveness ◽  
Extensive Literature ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
In Vivo Experiments ◽  
Cytotoxicity Activities ◽  
The University

Antidesma laciniatum and A. membranaceum are small trees used as traditional medicines in tropical Africa. This extensive literature review synthesizes the information currently available on the medicinal uses, phytochemistry and biological activities of A. laciniatum and A. membranaceum. The university library and electronic search engines such as Google Scholar, Scopus, Web of Science, ScienceDirect, and PubMed were searched for pertinent information on the medicinal uses, phytochemistry, and biological activities of A. laciniatum and A. membranaceum. Traditionally, the species have been used as aphrodisiac, and traditional medicine for cough, kwashiorkor, mouth ulcers, pneumonia, prevent miscarriage, snakebites, stomachache and wounds. Various phytochemicals such as essential oils, isoflavonoid glycosides, phytosterols, benzopyranones, lignin glucosides, megastigmane, phenolics, steroids, squalene, terpenoids, triterpenoids, and tetrahydroisoquinoline alkaloids have been isolated from A. laciniatum and A. membranaceum. In vitro studies have confirmed the biological activities of A. laciniatum and A. membranaceum which, include antimicrobial, antioxidant, antiplasmodial, antitrypanosomal, leishmanicidal, molluscicidal and cytotoxicity activities. More pharmacological studies including phytochemical, toxicological, in vitro and in vivo experiments are needed to provide evidence for the clinical effectiveness of remedies prepared from the species.

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