Efficacy of mite allergen immunotherapy in allergic rhinitis and the immune synergistic effect on cross-allergens

Immunotherapy ◽  
2021 ◽  
Author(s):  
Peiyan Zheng ◽  
Xiaoqing Liu ◽  
Lili Lin ◽  
Huiqin Wu ◽  
Xiaoming Zhao ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Visual Analogue Scale ◽  
Synergistic Effect ◽  
Analogue Scale ◽  
Large Scale ◽  
Allergen Immunotherapy ◽  
Early Stage ◽  
Mite Allergen ◽  
Basophil Activation ◽  
Controlled Study

Aim: To compare the efficacy of single- and double-species mite allergen immunotherapy. Materials and methods: An open, pseudo-randomized, controlled study was conducted (n = 125 allergic rhinitis patients). The primary end point involved the visual analogue scale. Secondary end points included a basophil activation test and serum specific IgE and IgG4 assays. Results: Visual analogue scale analysis indicated considerable reductions in both groups. Both treatments improved quality of life and induced sIgG4 antibody production. Basophil activation and serum IgE inhibition were not evident in either treatment. Neither treatment displayed an early stage immune synergistic effect on cross-allergens. Conclusions: Both treatments were effective against allergic rhinitis, and statistical differences were not observed. Future studies may require long-term, large-scale research.

Validation of the MASK-rhinitis visual analogue scale on smartphone screens to assess allergic rhinitis control

2017 ◽  
Vol 47 (12) ◽  
pp. 1526-1533 ◽  
Author(s):  
D. Caimmi ◽  
N. Baiz ◽  
L. K. Tanno ◽  
P. Demoly ◽  
S. Arnavielhe ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Visual Analogue Scale ◽  
Analogue Scale

scholarly journals Efficiency Of Intra-Articular Administration In Early Osteoarthrosis

2020 ◽  
Vol 02 (11) ◽  
pp. 22-27
Author(s):  
Islamova K. A . ◽  
◽  
Khasanov F. Sh ◽  
Toirov E. S. ◽  
◽  
...  
Keyword(s):  
Visual Analogue Scale ◽  
Knee Joint ◽  
Treatment Outcomes ◽  
Analogue Scale ◽  
Clinical Effect ◽  
Early Stage ◽  
Knee Joints ◽  
Joint Function ◽  
Early Osteoarthritis ◽  
Positive Clinical Effect

The purpose of this study was to investigate the function of knee joints in patients with early osteoarthritis (OA, according to the criteria of the American rheumatology Association 2010) stage I-III using visual analogue scale (VAS) for pain intensity and treatment outcomes, Lequesne index, expert indicators, samples of 4 meter walk to assess the effectiveness of intra-articular injection Hyaluronic Chondro. 80 patients aged 28 to 55 years were examined. The treatment regimen included recommendations from the European rheumatology League (EULAR, 2016) and Russia (Nasonov E. L., 2017). The results of therapy were evaluated in two groups. The first group included 43 patients who received Hyaluronic Chondro in the form of intra-articular injections, the second-37 patients who received chondroprotectors inside or in the form of intramuscular injections. Conclusion. Intra-articular administration of the drug Chondrogard has a positive clinical effect in early stage II-III OA with moderate impairment of knee joint function. The course of treatment should last at least 2 months

Acute perceptions of preferred cigarettes when blinded to brand

2018 ◽  
Vol 28 (3) ◽  
pp. 311-316 ◽  
Author(s):  
Kenneth A Perkins ◽  
Joshua L Karelitz
Keyword(s):  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Subjective Effects ◽  
Controlled Study ◽  
Cigarette Brand ◽  
Secondary Analyses ◽  
Tobacco Constituents ◽  
The Impact

BackgroundMarketing claims often have promoted specific perceptions that users should expect from acutely smoking that cigarette brand. Yet, little controlled study has determined the degree to which actual perceptions are based on the cigarette’s tobacco constituents in the absence of knowledge about the brand’s identity.Methods194 adult dependent smokers rated their perceptions on ‘liking’, ‘satisfying’, ‘strong’ and perceived amount of ‘nicotine’ after smoking ad lib one of their preferred brands of cigarettes. All did so either when blinded (n=118) or unblinded (n=76) to the brand they were given, with the blinding conditions from separate studies. These between-groups secondary analyses determined differences in perceptions based on blinding to brand, controlling for age and cigarettes/day.ResultsAll perceptions were lower for those smoking own brand under blinded versus unblinded conditions, as hypothesised. Consistent with lowered perceptions for smoking one’s own brand obtained from the 118 blinded to brand, their ‘somewhat’ ratings for a ‘how similar to own brand’ item indicated uncertainty, just mid-way between ‘not at all’ and ‘very much’ on the 0–100 visual analogue scale. (The 76 unblinded were already informed it was their own brand.)ConclusionsAcute perceptions of one’s own cigarette are substantially lower when smokers are simply unaware of brand, relative to those aware it is their preferred brand. Results support the notion that perceptions of smoking own brand are enhanced by marketing efforts to associate brands with expectations of pleasurable subjective effects, beyond the impact due solely to the cigarette’s manufactured product constituents.

Characteristics of Low Back Pain in Adolescent Patients With Early-Stage Spondylolysis Evaluated Using a Detailed Visual Analogue Scale

Spine ◽  
2015 ◽  
Vol 40 (1) ◽  
pp. E29-E34 ◽  
Author(s):  
Shiro Sugiura ◽  
Yasuchika Aoki ◽  
Takeshi Toyooka ◽  
Tetsuo Shiga ◽  
Kazumi Otsuki ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Early Stage ◽  
Low Back ◽  
Adolescent Patients

scholarly journals Comparison of Four Different Pain Relief Methods during Hysterosalpingography: A Randomized Controlled Study

2015 ◽  
Vol 20 (2) ◽  
pp. 107-111 ◽  
Author(s):  
Bekir Serdar Unlu ◽  
Mehmet Yilmazer ◽  
Gulengul Koken ◽  
Dagistan Tolga Arioz ◽  
Ebru Unlu ◽  
...  
Keyword(s):  
Pain Relief ◽  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Cervix Uteri ◽  
Controlled Study ◽  
Group 4 ◽  
Significant Difference ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

BACKGROUND: Hysterosalpingography (HSG) is the most commonly used method for evaluating the anatomy and patency of the uterine cavity and fallopian tubes, and is an important tool in the evaluation of infertility. The most frequent side effect is the pain associated with the procedure.OBJECTIVES: To evaluate four analgesic methods to determine the most useful method for reducing discomfort associated with HSG.METHODS: In the present prospective study, 75 patients undergoing HSG for evaluation of infertility were randomly assigned to four groups: 550 mg of a nonsteroidal anti-inflammatory drug (NSAID) (group 1); 550 mg NSAID + paracervical block (group 2); 550 mg NSAID + paracervical analgesic cream (group 3); or 550 mg NSAID + intrauterine analgesic instillation (group 4). A visual analogue scale was used to assess the pain perception at five predefined steps.RESULTS: Instillation of the liquids used for HSG was found to be the most painful step of HSG, and this step was where the only significant difference among groups was observed. When comparing visual analogue scale scores, group 2 and group 3 reported significantly less pain than the other groups. Group 1 reported significantly higher mean ( ± SD) scores (7.2 ± 1.6) compared with groups 2 and 3 (4.7 ± 2.5 and 3.8 ± 2.4, respectively) (P<0.001). In addition, group 2 reported significantly less pain than group 4 (4.7 ± 2.5 versus 6.7 ± 1.8, respectively) (P<0.02).CONCLUSIONS: For effective pain relief during HSG, in addition to 550 mg NSAID, local application of lidocaine cream to the posterior fornix of the cervix uteri and paracervical lidocaine injection into the cervix uteri appear to be the most effective methods.

Prophylactic and acute treatment with the homeopathic medicine Betula 30c for birch pollen allergy: a double-blind, randomized, placebo-controlled study of consistency of VAS responses

2001 ◽  
Vol 90 (02) ◽  
pp. 73-78 ◽  
Author(s):  
S Aabel
Keyword(s):  
Visual Analogue Scale ◽  
Analogue Scale ◽  
Pollen Season ◽  
Birch Pollen ◽  
Pollen Allergy ◽  
Controlled Study ◽  
Double Blind ◽  
Homeopathic Remedy ◽  
Birch Pollen Allergy ◽  
One Year

AbstractA study of the consistency of responses by allergic patients in repeated studies of the homeopathic remedy Betula 30c or placebo against birch pollen allergy, was made. A randomized, double-blind, placebo-controlled trial was performed including participants with a known allergy to birch pollen. Allergy symptoms were assessed on a visual analogue scale (VAS) by patients or parents each day during a 20-day period during two different pollen seasons. The work was carried out in Oslo, Norway during May 1995, 1996 and 1997. There were 51 patients ranging in age from 7 to 50 y. The homeopathic remedy Betula 30c or placebo was given as tablets, both as a prophylactic agent, once a week for 4 weeks before the pollen season started, and as an acute remedy during the pollen season. The mean value of the symptom scores on the visual analogue scale, for all registration days from each patient was the main outcome. The patient groups that received either placebo or Betula 30c for two successive years showed a consistent response (r=0.75, P=0.01 and r=0.70, P=0.003, respectively). No such correlation was found in the two groups that changed remedy from one year to another (either from placebo to Betula or vice versa). Subjective assessment of allergic symptoms to birch pollen differed more from one year to another when different regimens (placebo or homeopathic) had been administered these two seasons, than when the same treatment had been given.

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