scholarly journals Study Of Serum Uric Acid Level In patients With Systemic Lupus Erythematosus

2017 ◽  
Vol 4 (12) ◽  
pp. 84-92 ◽  
Author(s):  
Mahmoud Haddad Hemida ◽  
◽  
Farag Khalil ◽  
Hassan A. Gaber ◽  
◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Lupus Erythematosus ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Systemic Lupus

scholarly journals Serum Uric Acid is Associated with Renal Prognosis of Lupus Nephritis in Women but not in Men

2020 ◽  
Vol 9 (3) ◽  
pp. 773 ◽  
Author(s):  
Tae Ryom Oh ◽  
Hong Sang Choi ◽  
Chang Seong Kim ◽  
Dong-Ryeol Ryu ◽  
Sun-Hee Park ◽  
...  
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Lupus Nephritis ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Lupus Erythematosus ◽  
Acid Level ◽  
Independent Risk Factor ◽  
Serum Uric Acid Level ◽  
Cox Proportional Hazards

Lupus nephritis (LN) is a major complication of systemic lupus erythematosus. Early intervention in lupus nephritis improves prognosis. There is an association between hyperuricemia and lupus nephritis; nevertheless, the sex-specific role of uric acid in lupus nephritis remains unclear. We retrospectively analyzed 578 patients diagnosed with LN by renal biopsy. We determine the relationship of serum uric acid to progression of LN using Kaplan–Meier survival analyses and Cox proportional hazards models. The primary end point was LN progression defined as the initiation of dialysis or kidney transplantation. Men had higher mean serum uric acid levels than did women. Every 1 mg/dL increase in baseline uric acid level increased the risk of LN progression by 15.1%. The serum uric acid level was an independent risk factor for LN progression in women (hazard ratio [HR], 1.158; confidence interval [CI], 1.018–1.317; p = 0.028) but not in men (HR, 1.499; CI, 0.964–2.331; p = 0.072). Sensitivity analysis involving serum uric acid terciles generated consistent and robust results. Serum uric acid level was an independent risk factor for LN progression in women but not in men.

P0378SERUM URIC ACID IS ASSOCIATED WITH PROGNOSIS OF LUPUS NEPHRITIS IN FEMALE BUT NOT IN MALE

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Tae Ryon Oh ◽  
Hong Sang Choi ◽  
Chang Seong Kim ◽  
Soo Wan Kim ◽  
Eun Hui Bae ◽  
...  
Keyword(s):  
Uric Acid ◽  
Risk Factor ◽  
Lupus Nephritis ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Lupus Erythematosus ◽  
Acid Level ◽  
Independent Risk Factor ◽  
Serum Uric Acid Level ◽  
Cox Proportional Hazards

Abstract Background and Aims Lupus nephritis (LN) is one of the major complications of systemic lupus erythematosus. Early intervention in lupus nephritis is known to benefit patients' prognosis. Recent studies have found an association between hyperuricemia and lupus nephritis, but the sex-specific role of uric acid in lupus nephritis remains unclear. The purpose of this study is to elucidate the relationship between lupus nephritis and hyperuricemia, and to investigate sex differences. Method We retrospectively analyzed 394 patients who diagnosed with LN by renal biopsy. We assessed the effect of serum uric acid on progression of LN using Kaplan–Meier survival analyses and Cox proportional hazards models. The study’s primary end point was LN progression that was defined as the initiation of dialysis. Results The male had a higher mean of serum uric acid level than female. In the overall patient analysis, every 1 mg / dL increase in baseline uric acid level increased the risk of LN progression by about 16.9%. The serum uric acid level was an independent risk factor for LN progression in female (hazard ratio [HR], 1.177; confidence interval [CI],1.024 to 1.353; P<0.001) but not in male (HR, 1.0351; CI, 0.661 to 1.622; P = 0.880). A sensitivity analysis involving serum uric acid tertile generated consistent and robust results. Conclusion The serum uric acid level was an independent risk factor for LN progression in female but no in male.

AB0585 The Study on the Uric Acid Level of the Fertile Female Systemic Lupus Erythematosus Patients: Table 1.

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 1095.3-1096
Author(s):  
H.-J. Liu ◽  
J.-D. Ma ◽  
Y.-Q. Mo ◽  
D.-H. Zheng ◽  
X.-Y. Cai ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Uric Acid ◽  
Uric Acid Level ◽  
Lupus Erythematosus ◽  
Acid Level ◽  
Systemic Lupus ◽  
Fertile Female

A STUDY OF SERUM URIC ACID LEVELS IN PREECLAMPSIA

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Sushma Goad ◽  
Anita Verma ◽  
Subhash Chandra
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Control Group ◽  
Age Group ◽  
Hypertensive Disorders Of Pregnancy ◽  
Level Elevation ◽  
The Mean

Background: To Study Serum Uric Acid level elevation in Hypertensive Disorders of Pregnancy. Methods: 50 Patients diagnosed as having Pre-eclampsia with age between 18-37 years and 50 controls with similar age group. Results: The mean serum uric acid level in control group was 3.41 ± 0.62 and in patient 7.01 ± 0.58 which was statistically significant (p =0.001). Conclusion: Serum uric acid levels were significantly higher in preeclampsia could be a useful indicator of fetal complication in preeclampsia patients. Keywords: serum uric acid, preeclampsia, laboratory.

scholarly journals Synergic effect in the reduction of serum uric acid level between ethanol extract of Aster glehni and vitamin B6

2018 ◽  
Vol 27 (5) ◽  
pp. 1439-1444 ◽  
Author(s):  
Eun Hye Han ◽  
Mi Kyung Lim ◽  
Sang Ho Lee ◽  
Hyoung Ja Kim ◽  
Dahyun Hwang
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Vitamin B6 ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Ethanol Extract ◽  
Synergic Effect

scholarly journals Lung function decline is associated with serum uric acid in Korean health screening individuals

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyung-Min Ahn ◽  
Suh-Young Lee ◽  
So-Hee Lee ◽  
Sun-Sin Kim ◽  
Heung-Woo Park
Keyword(s):  
Uric Acid ◽  
Lung Function ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Forced Expiratory Volume ◽  
Linear Regression Models ◽  
Lung Function Decline ◽  
Health Screenings

AbstractWe performed a retrospective cohort study of 19,237 individuals who underwent at least three health screenings with follow-up periods of over 5 years to find a routinely checked serum marker that predicts lung function decline. Using linear regression models to analyze associations between the rate of decline in the forced expiratory volume in 1 s (FEV1) and the level of 10 serum markers (calcium, phosphorus, uric acid, total cholesterol, total protein, total bilirubin, alkaline phosphatase, aspartate aminotransferase, creatinine, and C-reactive protein) measured at two different times (at the first and third health screenings), we found that an increased uric acid level was significantly associated with an accelerated FEV1 decline (P = 0.0014 and P = 0.037, respectively) and reduced FEV1 predicted % (P = 0.0074 and P = 8.64 × 10–7, respectively) at both visits only in non-smoking individuals. In addition, we confirmed that accelerated forced vital capacity (FVC) and FEV1/FVC ratio declines were observed in non-smoking individuals with increased serum uric acid levels using linear mixed models. The serum uric acid level thus potentially predicts an acceleration in lung function decline in a non-smoking general population.

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