scholarly journals Preparation and Evaluation of Oral Dispersible Formulations of Amlodipine Besylate

1970 ◽  
Vol 7 (5) ◽  
pp. 42-55
Author(s):  
Akanksha Rai ◽  
Shalini Sharma
Keyword(s):  
Patient Compliance ◽  
Amlodipine Besylate ◽  
Hypertensive Drug ◽  
Mouth Feel ◽  
Preparation And Evaluation ◽  
Dose Form

Orally Dispersible type formulations became a really fashionable dose form as they disintegrate quickly (< one minute) within the mouth and don’t need water for administration. This is often thanks to the raised patient compliance, pleasant mouth feel, simple administration & swallowing and speedy disintegration and dissolution. vasodilative may be a hypertensive drug used for re-experiencing pressure.  

scholarly journals Preparation and Evaluation of Poly-γ-glutamic Acid Hydrogel Mixtures with Amlodipine Besylate: Effect on Ease of Swallowing and Taste Masking

2019 ◽  
Vol 67 (12) ◽  
pp. 1284-1292
Author(s):  
Honami Kojima ◽  
Tamami Haraguchi ◽  
Saeri Ikegami ◽  
Haruka Nishikawa ◽  
Miyako Yoshida ◽  
...  
Keyword(s):  
Glutamic Acid ◽  
Taste Masking ◽  
Amlodipine Besylate ◽  
Preparation And Evaluation

New bone density report format influences patient compliance in filling prescriptions for osteoporosis

2002 ◽  
Vol 2 (1) ◽  
pp. 13-18 ◽  
Author(s):  
Blair Greenwald ◽  
Avelina Bardwell ◽  
James Malinak ◽  
Robert Rude ◽  
Stuart L. Silverman ◽  
...  
Keyword(s):  
Bone Density ◽  
Patient Compliance

Evaluation of serum triglyceride levels as a marker of long-term patient compliance in diabetes mellitus type

2011 ◽  
Vol 6 (S 01) ◽  
Author(s):  
A Stylianou ◽  
G Lavranos ◽  
A Hatziyianni ◽  
P Georgiou ◽  
G Olymbios
Keyword(s):  
Diabetes Mellitus ◽  
Patient Compliance ◽  
Serum Triglyceride ◽  
Diabetes Mellitus Type

Does Increased Platelet Release Normalize During Anti-Hypertensive Treatment?

1987 ◽  
Vol 58 (03) ◽  
pp. 834-838
Author(s):  
Knut Lande ◽  
Sverre Erik Kjeldsen ◽  
Ivar Eide ◽  
Paul Leren ◽  
Knut Gjesdal
Keyword(s):  
Platelet Function ◽  
Adrenergic Receptor ◽  
Blood Platelet ◽  
Placebo Treatment ◽  
Sampling Procedure ◽  
Β Blocker ◽  
Platelet Release ◽  
Hypertensive Drug ◽  
Second Period ◽  
Release Product

SummaryBlood platelet function was evaluated in 10 men, all 50 years old, with untreated, mild hypertension. Each patient was examined four times: At the beginning of the study, after 5 weeks on placebo treatment, after the following 5 weeks on propranolol 160 mg daily, and finally after a second period of 5 weeks on placebo. At baseline the plasma level of the platelet release product (β-thromboglobulin (BTG) was 41.6 (30.5-57.0) μg/l (median and 95% confidence interval). During the first placebo period BTG was normalized to 21.0 (14.1-25.9) μg/l. While systolic blood pressure and heart rate fell during β-adrenergic receptor blockade, BTG remained unchanged throughout the rest of the observation periods. Platelet size increased significantly during treatment with β-blocker. The present study indicates that the normalization of elevated platelet function which previously has been reported to occur during anti-hypertensive drug therapy, may be explained by patient adaptation to the blood sampling procedure.

The Preparation and Evaluation of a Standardized Fibrin Plate for the Assessment of Fibrinolytic Activity

1970 ◽  
Vol 23 (02) ◽  
pp. 202-210 ◽  
Author(s):  
R Bishop ◽  
H Ekert ◽  
G Gilchrist ◽  
E Shanbrom ◽  
L Fekete
Keyword(s):  
Test Specimen ◽  
Fibrinolytic Activity ◽  
Clinical Laboratory ◽  
Fibrin Clot ◽  
Fibrinolytic Enzyme ◽  
Agarose Gel ◽  
Fibrin Plate ◽  
Percent Concentration ◽  
Human Plasminogen ◽  
Preparation And Evaluation

SummaryA new fibrin plate technic for evaluating components of the fibrinolytic system has been developed. It provides quick, accurate, and easily interpreted results for the fibrinolytic profile. The standardized human plasminogen-free fibrin plates can be produced in bulk and stored for prolonged periods of time. A test specimen placed in a well punched in the buffered agarose gel diffuses into the agar and lyses the fibrin clot, forming a clear reaction zone. The zone diameter is directly proportional to the log of the percent concentration of available fibrinolytic enzyme in the specimen. The plates may be used to quantitate total plasminogen, and estimate available plasmin and active plasmin. A good correlation between results obtained using these fibrin plates and caseinolytic methods was found. Performance and interpretation of tests of fibrinolysis done on these new fibrin plates indicate that it may be the most sensitive technic available for clinical laboratory work.

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