scholarly journals Melanoma of the Iris, Ciliary Body and Choroid in a Dog’s Poodle

2016 ◽  
Vol 44 (1) ◽  
pp. 4
Author(s):  
Luis Felipe Dutra Corrêa ◽  
Rafael Oliveira Chaves ◽  
Marília Teresa De Oliveira ◽  
João Pedro Scusssel Feranti ◽  
Bruna Copat ◽  
...  
Keyword(s):  
Ciliary Body ◽  
Histopathological Examination ◽  
Safety Margin ◽  
Corneal Opacity ◽  
Orbital Exenteration ◽  
Intact Male ◽  
German Shepherd ◽  
Iris Melanoma ◽  
Ocular Ultrasound ◽  
The Right

 Background: Melanoma is a primary ocular neoplasm that may affect the iris, ciliary body, the choroid coat and others components of the eye. The ocular melanomas have a low metastatic level in dogs when compared to cats. Old animals are more affected than the young ones and there is no breed predilection. A complete eye examination and ocular ultrasound will lead to the diagnosis that will be further confirmed through histopathology. Current treatment of choice is based on the size and the structures involved by the tumor that can range from local resection to orbital exenteration. The objective of this study is to report a case of iris melanoma involving the ciliary body and the choroid coat of a Poodle, emphasizing its clinical manifestation, diagnosis and treatment.Case: This study reports a case of an intact male canine Poodle, 15 years old, weighing 5 kg that was referred for care to the Veterinary Teaching Hospital of the Federal University of Santa Maria, Brazil. The owner initially presented a history of a progressive increase dark-colored intraocular volume in the right eye iris of the dog. On the clinical examination, no abnormality was found. On the ophthalmic examination, the right eye possessed misshapen pupil, hyperemia ocular conjunctiva (+) and diffuse corneal opacity (+) with paracentral pigmentation between 7-10 hour. On biomicroscopic ex­amination, using a slit lamp, it was observed an iris distension that was protruding directly into the anterior chamber and a diffuse opacity of the lens. Intraocular pressure was eight mmHg. B-mode ultrasonography revealed a mass involving the iris, ciliary body and the choroid coat with perilesional retinal detachment, suggesting iris ciliary body and choroid mela­noma. Due to the bad prognosis of the affected eye, the patient underwent to orbital exenteration procedure. The extracted eyeball was placed in 10% formalin and sent for histopathological examination, which was later reported as showing an iris melanoma involving the ciliary body and the choroid coat. The patient was re-examined six months postoperatively and no neoplasm recurrence signs were observed.Discussion: The animal stated in this report showed an increased volume of the right eye and dark pigmentation involving the iris. As highlighted by the actual literature, the size of this kind of neoplasm can vary from small to larger nodules and it can causes relevant anatomical changes. The pigmentation in these cases may vary from dark colors (black or brown) to white, for example, the amelanotic melanomas. In this report it was observed a nodular staining quite blackened pig­mentation. This kind of cancer involves mainly not neutered male dogs, with breed predilection as the German shepherd dogs, Golden Retrievers, Labrador Retrievers and also Poodles, as reported in this case. The treatment suggested by the literature, can range from diode laser therapy to microsurgical resection with enucleation or exenteration, depending on the size of the affected region and structures involved. The treatment of choice in this patient was the orbital exenteration because of the capacity of this tumor to spread throughout the uvea and it was not sure whether scleral infiltration could already exist, although the enucleation could also be indicated. However, through the histopathological examination, it could be confirmed that the neoplasm was located only at iris, involving also the ciliary body and choroid coat without sclera leakage, so there would be no need for exenteration. The average age of the patients is around nine years old ac­cording to published reports, namely older animals as the patient here described. The orbital exenteration technique, with good safety margin resection, proved to be efficient for the surgical treatment of iris melanoma involving the ciliary body and the choroid coat.Keywords: ophthalmology, neoplasm, uvea.

scholarly journals Management of dislocated nucleus with corneal opacity by combined deep anterior lamellar keratoplasty, pars- plana vitrectomy and phaco-fragmentation

2019 ◽  
Vol 12 (6) ◽  
pp. e229397
Author(s):  
Samendra Karkhur ◽  
Alok Sen ◽  
Gautam Parmar ◽  
Priyavrat Bhatia
Keyword(s):  
Ciliary Body ◽  
Surgical Intervention ◽  
Corneal Opacity ◽  
Ultrasound Biomicroscopy ◽  
Lamellar Keratoplasty ◽  
Deep Anterior Lamellar Keratoplasty ◽  
Anterior Lamellar Keratoplasty ◽  
Ciliary Processes ◽  
Pars Plana ◽  
The Right

A 32-year-old man presented with bilateral diminution of vision for 10 years. Visual acuity was light perception in both eyes with inaccurate projection in the oculus dextrus(OD) and accurate projection in the in oculus sinister (OS). Intraocular pressure was 6 and 12 mm Hg in the OD and OS, respectively. Slit-lamp examination revealed the presence of leucomatous corneal opacification with microcornea in oculus uterque (OU). Both eyes had a dislocated nucleus in the vitreous cavity on ultrasound B-scan with advanced cupping in the right eye. Ultrasound biomicroscopy revealed ciliary body atrophy in the OD and preserved ciliary processes (two quadrants) in the OS. In view of a partially preserved ciliary body function and a potential for gaining useful vision, we planned surgical intervention in the left eye. Deep anterior lamellar keratoplasty with pars planavitrectomy (PPV) and phacofragmentation of the nucleus was done. Donor lamellar graft was sutured after completion of PPV and nucleus fragmentation. The patient regained useful ambulatory vision postoperatively with clear corneal graft.

scholarly journals INTRAOCULAR TRANSMISSIBLE VENEREAL TUMOR IN A DOG

2001 ◽  
Vol 31 (1) ◽  
pp. 141-143 ◽  
Author(s):  
Geórgia Nadalini Rodrigues ◽  
Antonio Carlos Alessi ◽  
José Luiz Laus
Keyword(s):  
Lymph Nodes ◽  
Histopathological Examination ◽  
Intact Male ◽  
Susceptible Host ◽  
Cytologic Examination ◽  
Lymph Nodes Metastasis ◽  
Subcutaneous Nodules ◽  
Inguinal Area ◽  
History Of ◽  
The Right

Canine transmissible venereal tumor (TVT) is a round cell neoplasm occurring on the external genital mucosa of male and female dogs. Transmission is by cell implantation during coitus, licking, or other interaction between an affected dog and a susceptible host. Metastasis of the tumor rarely occurs. This report describes an unusual presentation of TVT with intraocular involvement and inguinal lymph nodes metastasis. The subject was a six-year-old, intact, male, Brazilian Terrier dog with a history of abnormal masses in the right eye, penis and several subcutaneous nodules in the inguinal area. Histopathological examination of the eye specimens as well as cytologic examination of penile mass and subcutaneous nodules revealed similar findings. The examination revealed round cells containing a large nuclei with prominent, central located nucleoli and a pale cytoplasm containing few small, clear round vacuoles. Histologically, the subcutaneous nodules in the inguinal area were lymph nodes. The diagnosis of TVT with intraocular involvement and lymph nodes metastasis was based on clinical, cytologic and histopathologic findings.

scholarly journals Two Late Recurrences of Conjunctival Melanoma

2018 ◽  
Vol 5 (4) ◽  
pp. 262-266 ◽  
Author(s):  
Niels J. Brouwer ◽  
Stijn W. Genders ◽  
Marina Marinkovic ◽  
Sjoerd G. van Duinen ◽  
Martine J. Jager ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Surgical Procedures ◽  
Histopathological Examination ◽  
Orbital Exenteration ◽  
Conjunctival Melanoma ◽  
Inferior Margin ◽  
Primary Acquired Melanosis ◽  
The Right ◽  
Additional Therapy

Purpose: To report a patient who developed two late recurrences of conjunctival melanoma (CoM), of which one occurred after orbital exenteration. Methods: We describe the case of a patient based on clinical and histopathological examination. Results: A 52-year-old patient was treated with local excision and cryotherapy for a CoM with primary acquired melanosis (PAM) near the limbus of the right eye. Twenty-one years later, a recurrence developed in the superior fornix of the same eye in an area with widespread PAM; an orbital exenteration was performed. After another 4 years, a painful nodule developed subcutaneously at the inferior margin of the right orbital socket. Pathology showed a recurrence of CoM with a BRAF V600K mutation, similar to both of the previous lesions (of 25 and 4 years earlier). The nodule was excised without additional therapy. No recurrences or metastases have been observed in the next 2.5 years. The proposed mechanism for the recurrence after surgery could be via dormant tumor cells that have spread prior to the procedure or via residual intraepithelial malignant melanocytes. Conclusion: Very late recurrences of CoM are rare but may occur. Our case illustrates the need for long-term awareness of doctors and patients, even after extensive surgical procedures such as orbital exenteration.

scholarly journals Pulmonary arteriovenous malformation in two adult alpacas (Vicugna pacos)

2011 ◽  
Vol 24 (1) ◽  
pp. 198-201 ◽  
Author(s):  
Susan Piripi ◽  
Jaime Hustace ◽  
Katelyn R. Carney ◽  
Jerry R. Heidel ◽  
Christiane V. Löhr
Keyword(s):  
Histopathological Examination ◽  
Vascular Anomaly ◽  
Extramedullary Hematopoiesis ◽  
Vascular Lesion ◽  
Intact Male ◽  
Lung Lobe ◽  
First Case ◽  
Vicugna Pacos ◽  
Severe Hemorrhage ◽  
The Right

Two cases of pulmonary vascular anomaly in unrelated adult alpacas ( Vicugna pacos) are described. In the first case, a 9-year-old intact male alpaca presented at Oregon State University Veterinary Teaching Hospital with bilateral epistaxis and died the subsequent day following severe hemorrhage from the mouth and nostrils. At necropsy, a tortuous vascular lesion was identified in the right cranial lung lobe, associated with hemorrhage into airways. In the second case, a 2-year-old female alpaca presented with postpartum anorexia, opisthotonus, and recumbency. In this second case, a similar vascular lesion was identified in the right cranial lung lobe but without associated hemorrhage. Histopathological examination of the lesion in both cases revealed numerous dilated, irregular blood vessels with marked variation in wall thickness within vessels, surrounded by foci of extramedullary hematopoiesis. Diagnoses of locally extensive pulmonary vascular anomalies (arteriovenous malformations) were made.

scholarly journals Bilateral Anophthalmia in Feline

2021 ◽  
Vol 49 ◽  
Author(s):  
Ana Claúdia De Souza Andrade ◽  
Laisa Marina Rosa Rey ◽  
Isabela Carvalho dos Santos ◽  
Lucas Lima Da Silva ◽  
Sarah Gabriella Delallo Charnovski ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Clinical Examination ◽  
Ultrasound Examination ◽  
Histopathological Examination ◽  
Cartilaginous Tissue ◽  
Histological Findings ◽  
Favorable Prognosis ◽  
Ocular Ultrasound ◽  
Congenital Anophthalmia ◽  
The Right

Background: Anophthalmia is a rare, congenital condition, defined as the complete absence of the eye bulb due to inadequate growth of the vesicle or optic dome. The malformation can be primary (in the absence of complete), secondary (in the presence of only residual tissue), or degenerative (in which the eye begins to form, but for some reason, it begins to degenerate). This condition is rare in dogs, cats, cattle, and sheep. Microscopic evaluation of orbital tissue for identification is always recommended. The aim of this study was to report a case of bilateral anophthalmia in a domestic cat.Case: A feline male, healthy, Maine Coon breed with 60 days of life was attended at the one veterinary private clinic. The cat, negative for FIV and FeLV, was born in a commercial cattery, belonging to his mother's third litter, healthy litter with the exception of this feline. He arrived with a complaint of not opening his eyelids, like the rest of the litter. In the clinical examination, it was found the normality of vital signs, absence of other visible anatomical abnormalities, only the ocular region was observed with closed eyelids. The initial suspicions were anophthalmia and microphthalmia. The patient was referred for an ocular ultrasound, which showed the complete absence of the right and left eye bulbs. The right and left orbital cavities had only a volume of soft, amorphous, and predominantly homogeneous tissue. After the ultrasound report, the patient underwent a surgical procedure to remove a fragment of tissue from the eye socket, which was sent for histopathological examination to confirm anophthalmia and discard the differential diagnosis of microphthalmia. Microscopy revealed immature, epithelial, and glandular tissue in the middle of discrete and moderate connective tissue, loosely arranged. In some fragments, cartilaginous tissue was also revealed. Thus, the histological findings are compatible with immature, pseudoformed tissues and without neoplastic characteristics. The diagnosis of secondary anophthalmia was reached with use of ultrasound and histological reports.Discussion: Congenital malformations in domestic cats are less frequent than in dogs, some of which are rare, and little reported. Secondary anophthalmia in the reported patient was confirmed by histological and ultrasound examination. Bilateral secondary anophthalmia is characterized by the absence of the eyeball, but with the presence of adjacent tissue. The animal was submitted to an ocular ultrasound examination and the complete absence of ocular bulbs was found. The differential diagnosis of microphthalmia was ruled out because there was no evidence of the eyeball. Microphthalmia is a common congenital ophthalmic disorder in veterinary medicine. Representative fragments were submitted to histopathological examination, where immature, epithelial tissue was found. In some fragments sent for analysis, cartilaginous tissue was observed. The histological findings are compatible with immature, pseudoformed tissues, thus verifying bilateral congenital anophthalmia in the reported animal. The clinical examination in these cases serves to ensure that the animal does not have any other congenital changes, allowing a favorable prognosis in puppies. Based on the information presented, the animal in this study has bilateral secondary congenital anophthalmia, with a favorable prognosis for the patient to live with certain normality, with quality and well-being.

scholarly journals Unusual presentation of ciliary body melanoma - a case report

2014 ◽  
Vol 11 (3) ◽  
pp. 287-289
Author(s):  
T Sarbajna ◽  
P Lavaju ◽  
M Agarwal ◽  
K Ahmad
Keyword(s):  
Case Report ◽  
Lacrimal Gland ◽  
Ciliary Body ◽  
Histopathological Examination ◽  
Temporal Region ◽  
Direct Extension ◽  
Tender Mass ◽  
Temporal Quadrant ◽  
The Right ◽  
Ciliary Body Melanoma

Background: Ciliary body melanoma rarely grows transclerally by direct extension and can metastasize locally into the orbit or conjunctiva. Objective: To report a case of ciliary body melanoma presenting clinically as a mass in the lacrimal gland region. Case: A 40-year-old female presented to the ophthalmic out-patient department with the complaint of a swelling in the right upper and outer lid region for 4 years. Ocular examination revealed a phthisical right eye. A firm, non-tender mass was palpable in the temporal quadrant of the right supraorbital region. Ultrasonography showed retinal detachment of the right eye. The CT-scan of the orbit was reportedly suggestive of a right lacrimal gland mass. Superolateral transperiosteal orbitotomy was planned for excision of the lacrimal gland mass. Intraoperatively, a well defined mass arising from the supero-temporal region of the right globe was noticed. The procedure was converted to enucleation of the right eye. Histopathological examination of the mass showed features of ciliary body melanoma. Conclusion: Extrascleral extension of ciliary body melanoma can present as a mass in the lacrimal gland region. DOI: http://dx.doi.org/10.3126/hren.v11i3.9657 Health Renaissance 2013;11(3):287-289

scholarly journals Radical management of aggressive lesions: a case report of recurrent ameloblastoma

2015 ◽  
Vol 63 (3) ◽  
pp. 327-330
Author(s):  
Carlos Henrique de CARVALHO E SOUZA ◽  
Jessyca Leal Moura FÉ ◽  
Lucas Lopes Araújo SOUSA ◽  
Márcia Socorro Da Costa BORBA ◽  
Simone Sousa Lobão Veras BARROS ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Safety Margin ◽  
Third Molar ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
Surrounding Tissue ◽  
En Bloc ◽  
High Local Recurrence Rate ◽  
Margin Of Safety ◽  
The Right

Ameloblastoma is an aggressive, benign odontogenic tumor of epithelial origin. Approximately 1-3% of all tumors and cysts of the maxillary bones are ameloblastomas. They grow at a slow but persistent rate and are mainly located in the ramus of the mandible. They are occasionally associated with the presence of an impacted third molar. Ameloblastomas are characterized by aggressive infiltration of the surrounding tissue. There may be a high local recurrence rate when the tumor is not properly removed, due to remaining tumor cells. This article reports a case of a multicystic ameloblastoma that had been previously treated with conservative therapy which failed and resulted in recurrence eight years later. Clinical examination showed extensive bone resorption in the right hemi-mandible region. Incisional biopsy and histopathological examination was carried out to confirm the diagnosis. The proposed treatment was total en bloc resection involving the right hemi-mandible, and the region of central and lateral left incisors with a two-centimeter safety margin. Radical surgical protocol with wide margin of safety must be adopted in order to prevent the recurrence of these aggressive tumors.

scholarly journals Ciliary body cysts associated with glaucoma in a Great Dane

2019 ◽  
Vol 70 (1) ◽  
pp. 1455
Author(s):  
E. PAPAVASILEIOU ◽  
P. DURIEUX
Keyword(s):  
High Resolution ◽  
Medical Treatment ◽  
Topical Treatment ◽  
Ciliary Body ◽  
Corneal Opacity ◽  
Applanation Tonometry ◽  
Initial Examination ◽  
Centre Hospitalier ◽  
The Right ◽  
Great Dane

An 8-year-old female Great Dane, was referred to the Ophthalmology Unit of the Centre Hospitalier Vétérinaire (CHV) des Cordeliers, for corneal opacity of the left eye that did not respond to topical treatment, administered by the referring vet. On initial examination, bilateral ciliary body cysts were noticed. Lens subluxation, pseudo-plateau iris and glaucoma were observed on the left eye. The diagnosis was confirmed by applanation tonometry and high resolution ocular ultrasonography. Medical treatment resulted in temporary clinical improvement of the left eye. No signs of glaucoma were observed on the right eye upon the last re-check examination.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

Safe Use of the Assimilative Capacity of the Marine Environment for Waste Disposal – Is It Feasible?

1986 ◽  
Vol 18 (4-5) ◽  
pp. 233-244 ◽  
Author(s):  
J. E. Portmann ◽  
R. Lloyd
Keyword(s):  
Marine Environment ◽  
Salt Marshes ◽  
Safety Margin ◽  
Assimilative Capacity ◽  
Anthropogenic Inputs ◽  
Upper Limit ◽  
Safe Limits ◽  
Control Authority ◽  
The Right ◽  
To Receive

For centuries the sea has absorbed a variety of inputs from rivers, streams, salt marshes and the atmosphere. It is generally accepted that additional limited inputs by man are unlikely to have a significant effect on the marine environment. Various control systems have been constructed to provide a framework within which the regulation of anthropogenic inputs can be achieved. These are briefly reviewed. With care, and in the light of past experience in both freshwater and marine environments, reasonable assumptions or estimations can be applied where uncertainties exist; safe limits can therefore be set for discharges. Case histories are used to illustrate the contention that it is possible to assess the assimilative capacity of a marine area to receive wastes. There is a major distinction to be drawn between contamination and pollution of the marine environment. Moreover, acknowledgement of the assimilative capacity concept in the marine environment does not automatically provide dischargers with the right to utilise that capacity either in part or to the upper limit. What it does is indicate the upper limit which must not be exceeded if pollution is to be avoided, and provide an indication to the control authority of the safety margin involved in the discharge limits they set accordingly.

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